Transfusion of banked red blood cells and the effects on hemorrheology and microvascular hemodynamics in anemic hematology outpatients.

abstract：BACKGROUND:Storage age of red blood cells (RBCs) has been reported to be associated with increased mortality and morbidity. During storage, RBCs undergo changes in biochemical and functional properties. Stored RBCs may also contain white blood cells (WBCs), activated platelets (PLTs), cytokines, immunoglobulin, and oth...

journal_title：Transfusion

authors： Sowemimo-Coker SO

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Iron deficiency represents a risk to donor health and the blood supply. Efficacy trials indicate that postdonation iron replacement improves iron stores but they do not account for complexities of implementation in the routine collection context. We therefore conducted two prospective feasibility studies in ...

journal_title：Transfusion

authors： Pasricha SR,Marks DC,Salvin H,Brama T,Keller AJ,Pink J,Speedy J

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:In sub-Saharan Africa (SSA) confirmed viral marker prevalence between family donors (FDs) and first-time volunteer nonremunerated donors (VNRDs) is similar. In a blood service collecting 10 units/1000 inhabitants, a questionnaire examined FD donation conditions and willingness of becoming repeat VNRDs. STUD...

journal_title：Transfusion

authors： Asenso-Mensah K,Achina G,Appiah R,Owusu-Ofori S,Allain JP

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:An HIV-1 and HCV NAT blood screening assay (Procleix HIV-1/HCV, Gen-Probe, Inc.) simultaneously detecting HIV-1 and HCV RNA) has been implemented. Donor plasma samples reactive in the Procleix HIV-1/HCV assay are tested with the HIV-1 and HCV discriminatory assays to resolve whether HIV-1 RNA, HCV RNA, or bo...

journal_title：Transfusion

authors： Vargo J,Smith K,Knott C,Wang S,Fang C,McDonough S,Giachetti C,Caglioti S,Gammon R,Gilbert D,Jackson JB,Richards W,Stramer S,Mimms L

更新日期：2002-07-01 00:00:00

abstract：:Monitoring of platelet counts 1 hour after transfusion has become standard practice in most centers. In this study, platelet counts obtained 10 and 60 minutes after 48 platelet transfusions were compared. There was a close, linear relationship (r = 0.98) between these values over a wide range of posttransfusion counts...

journal_title：Transfusion

authors： O'Connell B,Lee EJ,Schiffer CA

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Screening of blood donations for antibodies against hepatitis B core antigen (anti-HBc) is an accepted method to prevent some transfusion-transmitted hepatitis B virus (HBV) infections. However, anti-HBc testing may result in donor loss due to unspecific results in the currently available anti-HBc tests. Alg...

journal_title：Transfusion

authors： Juhl D,Luhm J,Görg S,Ziemann M,Hennig H

更新日期：2011-07-01 00:00:00

abstract：:The development of flexible plastic blood bags has permitted effective blood component production and therapy. However, the plasticizer di(2-ethylhexyl)phthalate (DEHP), whose toxicity in humans is still undefined, is known to leach from the plastic into stored blood. Despite the availability of bags made of plastics ...

journal_title：Transfusion

authors： Rock G,Tocchi M,Ganz PR,Tackaberry ES

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Patients with acute myeloid leukemia (AML) with hyperleukocytosis of at least 100 x 10(9) per L are at high risk of early death due to pulmonary or cerebral leukostasis. Although the efficacy of leukapheresis in terms of prompt cytoreduction is generally accepted, published data regarding the clinical value ...

journal_title：Transfusion

authors： Bug G,Anargyrou K,Tonn T,Bialleck H,Seifried E,Hoelzer D,Ottmann OG

更新日期：2007-10-01 00:00:00

abstract：:The authors describe a prototype elution method employing chloroquine, a quinoline derivative, to elute IgG antibodies from the platelet surface. This chloroquine elution technique is relatively easy to perform and is effective in the removal of alloantibodies from the platelet surface. Eluted alloantibody was immunol...

journal_title：Transfusion

authors： Masel DS,Blumberg N,Heal JM

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Advances in the past two decades in dendritic cell (DC) biology paved the way to exploit them as a promising tool in cancer immunotherapy. The prerequisite for DC vaccine preparations is large-scale in vitro generations of homogeneous, mature, and functional DCs. Frequent improvements are being made in the e...

journal_title：Transfusion

authors： Balan S,Kale VP,Limaye LS

更新日期：2010-11-01 00:00:00

abstract：:Evidence supporting the existence of two agents of human non-A, non-B hepatitis was obtained by the inoculation of chimpanzees sequentially with serum from a chronically infected human (Inoculum I) and with fibrinogen prepared from pooled plasma (Inoculum IV), each of which had transmitted non-A, non-B hepatitis to hu...

journal_title：Transfusion

authors： Tabor E,Snoy P,Jackson DR,Schaff Z,Blatt PM,Gerety RJ

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:With the coronavirus disease 2019 (COVID-19) pandemic continuing to accelerate and blood collection agencies (BCAs) warning of shortages, it is critical to identify the current determinants of donor behavior for donors and nondonors. STUDY DESIGN AND METHODS:In May and June 2020, Australian residents who be...

journal_title：Transfusion

authors： Masser BM,Hyde MK,Ferguson E

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) transfusions are essential for patients who are bleeding or have an increased risk of bleeding due to a decreased number or abnormal function of circulating PLTs. A shelf life of 5 days for PLT products presents an inventory management challenge. In 2006, greater than 10% of apheresis PLTs mad...

journal_title：Transfusion

authors： Fuller AK,Uglik KM,Braine HG,King KE

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Treating hemorrhage with blood transfusions in subjects previously hemodiluted with different colloidal plasma expanders, using fresh autologous blood or blood that has been stored for 2 weeks, allows identifying the interaction between type of plasma expander and differences in blood storage. STUDY DESIGN ...

journal_title：Transfusion

authors： Hightower CM,Salazar Vázquez BY,Cabrales P,Tsai AG,Acharya SA,Intaglietta M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:We assessed donor return rates, donation frequency, and factors related to the evolution of ferritin levels 2 years after entering donors into a large operational study of ferritin testing. STUDY DESIGN AND METHODS:Ferritin testing was done on donors from representative clinics (n = 12,595). Low-ferritin do...

journal_title：Transfusion

authors： Goldman M,Uzicanin S,Osmond L,Yi QL,Scalia V,O'Brien SF

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Human herpesvirus 8 (HHV-8) seroprevalence ranges between less than 5% in Europe and North America and 50% to 70% in sub-Saharan Africa. Evidence of HHV-8 transfusion transmission is only indirect. We conducted a serologic (anti-HHV-8) and molecular (HHV-8 DNA) study of samples from paired donor-immunocompet...

journal_title：Transfusion

authors： Gobbini F,Owusu-Ofori S,Marcelin AG,Candotti D,Allain JP

更新日期：2012-11-01 00:00:00

abstract：:An example is presented of an IgG1, anti-Lu6, that reacted by indirect antiglobulin test and was capable of destroying antigen-positive red cells in vivo. Two methods for the measurement of red cell survival, 51Cr labeling and flow cytometry, gave the same result: 20 percent of the test dose of Lu:6 red cells was dest...

journal_title：Transfusion

authors： Issitt PD,Valinsky JE,Marsh WL,DiNapoli J,Gutgsell NS

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Hemolysis at the time of graft infusion is one of the immediate complications in major ABO-incompatible allogeneic hematopoietic stem cell transplants (HSCTs). We conducted a retrospective analysis to evaluate the efficacy of donor-type fresh frozen plasma (FFP) in reducing isohemagglutinin titer and prevent...

journal_title：Transfusion

authors： Quek J,Lee JJ,Lim FL,Diong C,Goh YT,Gopalakrishnan S,Ho A,Hwang W,Koh M,Loh Y,Linn YC

更新日期：2019-01-01 00:00:00

abstract：:Intravenous iron-dextran therapy can cause a red-brown discoloration of the plasma, simulating a hemolytic transfusion reaction. A rapid and simple test to differentiate between true hemolysis and plasma discoloration due to circulating iron-dextran complexes is described. ...

journal_title：Transfusion

authors： Simon SD,Kuriyan MA,Kim HC

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:The temporal pattern of the biologic mechanism linking red blood cell (RBC) storage duration with clinical outcomes is yet unknown. This study investigates how such a temporal pattern can affect the power of randomized controlled trials (RCT) to detect a relevant clinical outcome mediated by the transfusion ...

journal_title：Transfusion

authors： Pereira A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Drug-induced immune thrombocytopenia (DITP) is a serious, life-threatening clinical syndrome, the diagnosis of which is consistently difficult. In this report, we present a case of DITP caused by meropenem that was confirmed by laboratory tests. CASE REPORT:A 59-year-old male patient developed severe thromb...

journal_title：Transfusion

authors： Huang R,Cai GQ,Zhang JH,Liu FX,Ma JQ,Liu H,Nie XM,Gui R

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Immunomodulatory effects of UV light have increasingly become a focus in transfusion medicine, BMT and transplantation immunology. In the transplant setting, the use of UVB radiation may reduce or abolish T-cell activation without compromising either bone marrow (BM) engraftment or graft-versus-leukemia effe...

journal_title：Transfusion

authors： Lankford KV,Mosunjac M,Hillyer CD

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:This study reports the incidence of Wr(a) antigen and anti-Wr(a) in Valencia, Spain. STUDY DESIGN AND METHODS:The incidence of the Wr(a) antigen in 110,000 healthy blood donors was estimated. Likewise, the incidence of anti-Wr(a) was analyzed in a population consisting of 730 healthy blood donors, 356 pregn...

journal_title：Transfusion

authors： Arriaga F,Llopis F,de la Rubia J,Carpio N,Moscardó J,Marty ML

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:The history of the development and implementation of the Brazilian nucleic acid testing (NAT) platform to detect and discriminate among human immunodeficiency virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) infections in blood donors is described here. The results for the sensitivity, repro...

journal_title：Transfusion

authors： Rocha D,Andrade E,Godoy DT,Fontana-Maurell M,Costa E,Ribeiro M,Ferreira AGP,Brindeiro R,Tanuri A,Alvarez P

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The successful mobilization and collection of hematopoietic stem cells are dependent on a number of clinical factors such as previous chemotherapy and disease stage. The aim of this retrospective study was to determine whether the effectiveness of mobilization and collection is an independent prognostic fact...

journal_title：Transfusion

authors： Wang S,Nademanee A,Qian D,Dagis A,Park HS,Fridey J,Smith E,Snyder D,Somlo G,Stein A,Rosenthal J,Falk P,Kogut N,Palmer J,Gaal K,Kim Y,Bhatia R,Yuan S,Kay C,Weiss L,Forman S

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Antibodies produced against the D antigen make use of IGHV genes restricted to the IGHV3 superfamily. These findings are based on the IGHV gene analysis in anti-D-producing B cells from hyperimmunized donors, however, and therefore the restriction might be due to the hyperimmunization. In this study the IGHV...

journal_title：Transfusion

authors： Dohmen SE,Verhagen OJ,Muit J,Ligthart PC,van der Schoot CE

更新日期：2006-12-01 00:00:00

abstract：:The anti-A response in a group B patient accidentally given 1 unit transfusion of A1 blood is described. The antibody response is characterized both with conventional agglutination techniques and with radioimmunoassay using pure group A antigens with different core saccharide structures (type 1, 2, and 4 chains) and c...

journal_title：Transfusion

authors： Rydberg L,Breimer ME,Samuelsson BE

更新日期：1988-09-01 00:00:00

abstract：:The whole blood electrical conductivity method for predonation hematocrit determinations was studied. Forty capillary and venous blood samples were tested concurrently with electrical conductivity and centrifugation methods. The electrical conductivity method demonstrated acceptable accuracy but was less precise than ...

journal_title：Transfusion

authors： Schifman RB,Rivers SL,Delduca M

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Clinical outcomes in transfused patients may be affected by the duration of blood storage, possibly due to red blood cell (RBC)-mediated disruption of nitric oxide (NO) signaling, a key regulator of vascular tone and blood flow. STUDY DESIGN AND METHODS:AS-1 RBC units stored up to 42 days were sampled at se...

journal_title：Transfusion

authors： Alexander JT,El-Ali AM,Newman JL,Karatela S,Predmore BL,Lefer DJ,Sutliff RL,Roback JD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Patients presenting with acute episodes of thrombotic microangiopathies (TMAs) require urgent access to plasma exchange (PEX). OctaplasLG, a solvent/detergent fresh-frozen plasma product that has undergone viral inactivation and prion reduction step, has been used in our institution since 2013, replacing Oct...

journal_title：Transfusion

authors： Vendramin C,McGuckin S,Alwan F,Westwood JP,Thomas M,Scully M

更新日期：2017-01-01 00:00:00