Abstract:
:The anti-A response in a group B patient accidentally given 1 unit transfusion of A1 blood is described. The antibody response is characterized both with conventional agglutination techniques and with radioimmunoassay using pure group A antigens with different core saccharide structures (type 1, 2, and 4 chains) and class-specific second antibodies. The anti-A titer rose to a maximum Days 11 to 14 after the incompatible transfusion. The antibodies involved were mainly of the IgG and IgA types, while the IgM response was moderate. The IgA antibodies seemed to be nonselective with respect to group A antigen type, while the IgG antibodies showed a specificity against type 2 chain group A antigens.
journal_name
Transfusionjournal_title
Transfusionauthors
Rydberg L,Breimer ME,Samuelsson BEdoi
10.1046/j.1537-2995.1988.28588337343.xsubject
Has Abstractpub_date
1988-09-01 00:00:00pages
483-8issue
5eissn
0041-1132issn
1537-2995journal_volume
28pub_type
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