Ultrastructural localization of glycoprotein IIIa (GPIIIa, beta 3 integrin) on placental syncytiotrophoblast microvilli: implications for platelet alloimmunization during pregnancy.

abstract：BACKGROUND:Routine HCV NAT of blood donors to detect persons in the preseroconversion phase of acute infection was introduced in Canada in October 1999. The source of virus exposure was investigated in the first, and to date only, blood donor found to be HCV NAT positive, anti-HCV negative in Canada. He was a regular d...

journal_title：Transfusion

authors： Larke B,Hu YW,Krajden M,Scalia V,Byrne SK,Boychuk LR,Klein J

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloantibodies to nonself antigens may develop after transfusion or pregnancy, leading to morbidity and mortality in the form of hemolytic transfusion reactions or hemolytic disease of the newborn. A better understanding of the mechanisms of RBC alloantibody induction, or strategies to m...

journal_title：Transfusion

authors： Stowell SR,Girard-Pierce KR,Smith NH,Henry KL,Arthur CM,Zimring JC,Hendrickson JE

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Eleven laboratories participated in a study investigating whether swirling can be used in monitoring platelet discoid morphology in platelet concentrates (PCs). STUDY DESIGN AND METHODS:In each laboratory, two readers observed the swirling pattern in 1- to 5-day-old PCs, in PCs containing spherical platelet...

journal_title：Transfusion

authors： Bertolini F,Murphy S

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:The von Willebrand factor (VWF)-cleaving protease, ADAMTS13, is often deficient in cases of thrombotic thrombocytopenic purpura (TTP). The primary treatment of TTP is therapeutic plasma exchange (TPE) utilizing a variety of plasma products that help restore ADAMTS13 activity. However, multiple replacement pr...

journal_title：Transfusion

authors： Scott EA,Puca KE,Pietz BC,Duchateau BK,Friedman KD

更新日期：2007-01-01 00:00:00

abstract：:Social and economic development, along with increased health care coverage, has caused a sharp increase in the clinical demand for blood in China. Whole blood collection has increased rapidly in the past decade but has failed to keep pace with the ever-increasing demand. Overall, the country's blood safety has been im...

journal_title：Transfusion

authors： Shi L,Wang JX,Stevens L,Ness P,Shan H

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Evaluation of hemostasis in bleeding patients requires both accuracy and speed. STUDY DESIGN AND METHODS:As an alternative to point-of-care testing, we developed an emergency hemorrhage panel (EHP: prothrombin time [PT], fibrinogen, platelet count, hematocrit) for use in making transfusion decisions on blee...

journal_title：Transfusion

authors： Chandler WL,Ferrell C,Trimble S,Moody S

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The survival of fresh and preserved platelets has been used primarily to determine their therapeutic effectiveness. The function of the fresh and preserved platelets has been difficult to assess. In stable thrombocytopenic patients, platelet function of fresh and preserved allogeneic platelets is evaluated b...

journal_title：Transfusion

authors： Valeri CR,MacGregor H,Giorgio A,Ragno G

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Platelet factor 4 (PF4) is a marker for in vitro and in vivo tests of platelet (PLT) activation and alpha-granule secretion. PF4 is also a major CXC cytokine released during storage. Cytokines released during PLT storage are a potential cause of nonhemolytic transfusion reactions. Quantitative measurement of...

journal_title：Transfusion

authors： Schraw T,Whiteheart S

更新日期：2005-05-01 00:00:00

abstract：:Sera from three unrelated persons whose red cells (RBC) had the common Scianna phenotype (Sc:1,-2) contained IgG alloantibodies directed against high-frequency RBC antigens. In each case, sera or eluates or both failed to react only with Scianna null (Sc:-1,-2) cells, although an eluate from one person was compatible ...

journal_title：Transfusion

authors： Devine P,Dawson FE,Motschman TL,Skradski KJ,Orsini L,Moulds JJ,Taswell HF

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Monitoring blood transfusion for overutilization is standard practice at most institutions. STUDY DESIGN AND METHODS:This study monitored for underutilization of blood transfusion over a 14-month period, by evaluating patients who had Hb levels that were reported to be <5 g per dL or platelet counts <10 x 1...

journal_title：Transfusion

authors： Saxena S,Wehrli G,Makarewicz K,Sartorelli J,Shulman IA

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:The RHD gene is flanked by two highly homologous DNA segments of approximately 9000 bp, the upstream and downstream Rhesus boxes. In haplotypes with an RHD deletion, the fusion of the two Rhesus boxes generates the single-hybrid Rhesus box, the detection of which has been applied for RHD zygosity determinati...

journal_title：Transfusion

authors： Wagner FF,Moulds JM,Flegel WA

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Borrelia miyamotoi, a recently discovered relapsing fever spirochete, occurs in hard-bodied ticks wherever Lyme disease is endemic. Human infection is associated with relapsing fever and can cause meningoencephalitis in immunocompromised patients. A few cases of transfusion transmission of other relapsing fe...

journal_title：Transfusion

authors： Krause PJ,Hendrickson JE,Steeves TK,Fish D

更新日期：2015-03-01 00:00:00

abstract：:With an interval of eight weeks between collections, blood was drawn twice from 120 blood donors. At one of the donations, 0.25 ml of synthetic vasopressin, (DDAVP, 1300 micrograms/ml), was administered intranasally 60 minutes prior to collection of the blood. No drug was given at the other donation. The yield of fact...

journal_title：Transfusion

authors： Mikaelsson M,Nilsson IM,Vilhardt H,Wiechel B

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Fc gamma RIIIb deficiency is a rare defect in which neutrophils do not express Fc gamma RIIIb and therefore the individuals with this defect have an NA null phenotype. Soluble Fc gamma RIII in plasma is severely decreased and almost undetectable. During pregnancy, Fc gamma RIIIb deficiency may cause the form...

journal_title：Transfusion

authors： Puig N,de Haas M,Kleijer M,Montoro JA,Pérez A,Villalba JV,Gomez I,von dem Borne AE

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Storage of blood units (for 35-42 days, depending on the preservative solution) has been reported to induce changes (e.g., reduction of sialic acid level) in red cells that are expected to alter their aggregability. STUDY DESIGN AND METHODS:The aggregability of stored red cells was monitored in their autolo...

journal_title：Transfusion

authors： Hovav T,Yedgar S,Manny N,Barshtein G

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Pulmonary transfusion reactions are important complications of blood transfusion, yet differentiating these clinical syndromes is diagnostically challenging. We hypothesized that biologic markers of inflammation could be used in conjunction with clinical predictors to distinguish transfusion-related acute lu...

journal_title：Transfusion

authors： Roubinian NH,Looney MR,Kor DJ,Lowell CA,Gajic O,Hubmayr RD,Gropper MA,Koenigsberg M,Wilson GA,Matthay MA,Toy P,Murphy EL,TRALI Study Group.

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Intracellular glutathione declines progressively in platelet concentrates stored for transfusion, but little is known about the nature of this process. STUDY DESIGN AND METHODS:Acivicin, an irreversible inhibitor of gamma-glutamyl transpeptidase, was used to determine the fate of glutathione lost from plate...

journal_title：Transfusion

authors： Burch PT,Aman M,Burch JW

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Patients presenting with acute episodes of thrombotic microangiopathies (TMAs) require urgent access to plasma exchange (PEX). OctaplasLG, a solvent/detergent fresh-frozen plasma product that has undergone viral inactivation and prion reduction step, has been used in our institution since 2013, replacing Oct...

journal_title：Transfusion

authors： Vendramin C,McGuckin S,Alwan F,Westwood JP,Thomas M,Scully M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Platelets (PLTs) contain purinergic receptors for ATP (P2X1) and ADP (P2Y1 and P2Y12) that rapidly desensitize upon stimulation with these nucleotides. In vivo, this is antagonized by ectonucleotidases on the surface of endothelial cells and white blood cells (WBCs). The receptor desensitization of ATP- and ...

journal_title：Transfusion

authors： Cauwenberghs S,Feijge MA,Hageman G,Hoylaerts M,Akkerman JW,Curvers J,Heemskerk JW

更新日期：2006-06-01 00:00:00

abstract：:Anti-Emm, an antibody to a public red cell antigen, was found in the serums of four Emm-propositi and in the serum of the Emm-brother of one of them. Three of the propositi were men, and their antibodies, as well as that of the compatible brother, were believed to be "naturally occurring." Since there are two Emm-sibl...

journal_title：Transfusion

authors： Daniels GL,Taliano V,Klein MT,McCreary J

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:The high-prevalence antigen Jr(a) is carried on the ATP-binding cassette transporter ABCG2. The ABCG2 gene consists of 16 exons and its translation start codon is located on the second exon. Although the occurrence of the Jr(a-) phenotype is rare, several ABCG2 null alleles have been reported. We report a ne...

journal_title：Transfusion

authors： Ogasawara K,Osabe T,Suzuki Y,Tsuneyama H,Isa K,Kawai M,Obara K,Ogiyama Y,Ito S,Uchikawa M,Satake M,Tadokoro K

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Some low-incidence antigens in the Rh blood group system (e.g., VS, Rh32, FPTT) are expressed by more than one Rh complex. We describe a new low-incidence antigen that is present on RBCs with the partial D phenotypes, DIIIa or DOL, on RN RBCs and on one example of STEM+S RBCs. STUDY DESIGN AND METHODS:Stand...

journal_title：Transfusion

authors： Reid ME,Storry JR,Sausais L,Tossas E,Rios M,Hue-Roye K,Gloster ES,Miller ST,Wolf C,Lomas-Francis C

更新日期：2003-10-01 00:00:00

abstract：:The US Food and Drug Administration (FDA) held a workshop on red blood cell (RBC) product regulatory science on October 6 and 7, 2016, at the Natcher Conference Center on the National Institutes of Health (NIH) Campus in Bethesda, Maryland. The workshop was supported by the National Heart, Lung, and Blood Institute, N...

journal_title：Transfusion

authors： Vostal JG,Buehler PW,Gelderman MP,Alayash AI,Doctor A,Zimring JC,Glynn SA,Hess JR,Klein H,Acker JP,Spinella PC,D'Alessandro A,Palsson B,Raife TJ,Busch MP,McMahon TJ,Intaglietta M,Swartz HM,Dubick MA,Cardin S,Patel

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) is a rare but serious adverse transfusion reaction and is known to be related to anti-human leukocyte antigen (HLA) or anti-human neutrophil antigen (HNA) antibodies in donor plasma. In 2016, four of eight reported TRALI cases could not be explained by donor anti...

journal_title：Transfusion

authors： De Clippel D,Emonds MP,Compernolle V

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Recovery and half-life estimations were carried out to compare a high-purity factor IX concentrate with an established factor IX complex concentrate. STUDY DESIGN AND METHODS:Two high-purity factor IX concentrates, which are identical except for the presence or absence of heparin (Immuninehep-plus and Immun...

journal_title：Transfusion

authors： Poon MC,Aledort LM,Anderle K,Kunschak M,Morfini M

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Extracellular potassium concentration (K(+)) increases in the supernatant of whole and packed red blood cell units (pRBCs) with duration of refrigerated storage in citrate-phosphate-dextrose-adenine (CPDA-1) and additive solution (AS). Studies have shown that to avoid hyperkalemia, washed pRBCs are preferred...

journal_title：Transfusion

authors： Bansal I,Calhoun BW,Joseph C,Pothiawala M,Baron BW

更新日期：2007-02-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), BRIC 66 (IgM) and BRIC 111 (IgG1), were produced by immunizing mice with ovarian cyst blood group A1 glycoprotein and Tn red cells (RBCs), respectively. Their specificities were determined by inhibitions using Tn sialoglycoproteins (SGPs), mucins (armadillo [ASG] and ovine [OSG] subm...

journal_title：Transfusion

authors： King MJ,Parsons SF,Wu AM,Jones N

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Viral contamination of platelet (PLT) concentrates can result in transfusion-transmitted diseases. A photochemical treatment (PCT) process with amotosalen-HCl and long-wavelength ultraviolet light (UVA), which cross-links nucleic acids, was developed to inactivate viruses and other pathogens in PLT concentra...

journal_title：Transfusion

authors： Lin L,Hanson CV,Alter HJ,Jauvin V,Bernard KA,Murthy KK,Metzel P,Corash L

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:We assessed donor return rates, donation frequency, and factors related to the evolution of ferritin levels 2 years after entering donors into a large operational study of ferritin testing. STUDY DESIGN AND METHODS:Ferritin testing was done on donors from representative clinics (n = 12,595). Low-ferritin do...

journal_title：Transfusion

authors： Goldman M,Uzicanin S,Osmond L,Yi QL,Scalia V,O'Brien SF

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Several drugs can cause immune hemolytic anemia. Here a patient who developed hemolytic anemia after treatment with teicoplanin is described. CASE REPORT:Owing to a two-vessel disease, a 68-year-old white man underwent coronary artery bypass grafting. He was readmitted for superficial sternal wound infectio...

journal_title：Transfusion

authors： Coluccio E,Villa MA,Villa E,Morelati F,Revelli N,Paccapelo C,Garratty G,Rebulla P

更新日期：2004-01-01 00:00:00