A new ABCG2 null allele with a 27-kb deletion including the promoter region causing the Jr(a-) phenotype.

abstract：BACKGROUND:The incidence of bloodborne AIDS and the total incidence of AIDS in various areas of the United States are strongly correlated. STUDY DESIGN AND METHODS:To determine whether the same held true for Western Europe, data for 1985 through 1993 from the World Health Organization's European Non-Aggregate AIDS Dat...

journal_title：Transfusion

authors： Dal Maso L,Franceschi S,Lo Re A,De Angelis V,La Vecchia C

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:To prevent donor loss and improve retention, it is important to understand the major deterrents to blood donation and to identify factors that can be effectively addressed by blood centers. STUDY DESIGN AND METHODS:A 30-item self-administered questionnaire was completed in 2003 by 1705 first-time and 2437 r...

journal_title：Transfusion

authors： Schreiber GB,Schlumpf KS,Glynn SA,Wright DJ,Tu Y,King MR,Higgins MJ,Kessler D,Gilcher R,Nass CC,Guiltinan AM,National Heart, Lung, Blood Institute Retrovirus Epidemiology Donor Study.

更新日期：2006-04-01 00:00:00

abstract：:Interest has been renewed in CPD-adenine as a long-term liquid blood preservative. The question of whether the metabolic product of adenine, 2,8-dioxyadenine was toxic to humans has apparently been resolved by extensive animal and human studies in favor of there being no potential toxicity in the amounts used in blood...

journal_title：Transfusion

authors： Dawson RB,Ellis TJ,Hershey RT

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Beriplex P/N/Kcentra/Coaplex/Confidex is a four-factor human prothrombin complex concentrate (PCC). Here, we describe the pathogen safety profile and biochemical characteristics of an improved manufacturing process that further enhances the virus safety of Beriplex P/N. STUDY DESIGN AND METHODS:Samples of p...

journal_title：Transfusion

authors： Nowak T,Popp B,Gröner A,Schäfer W,Kalina U,Enssle K,Roth NJ

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:The 2016 Food and Drug Administration draft guidance describes the use of a rapid test (RT) to enhance platelet transfusion safety and availability. This study reports a 113-month experience of screening of apheresis platelets (APs) by RT. STUDY DESIGN AND METHODS:From July 2008 to October 2015, all APs und...

journal_title：Transfusion

authors： Ruby KN,Thomasson RR,Szczepiorkowski ZM,Dunbar NM

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Although the standard classification system for acute transfusion reactions adequately describes the general features associated with the various types of reactions, it was not designed to provide strict criteria for diagnosis and classification. Consequently, its use to classify individual reactions can res...

journal_title：Transfusion

authors： Sanders RP,Geiger TL,Heddle N,Pui CH,Howard SC

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Although the risk of transmitting infectious agents by blood transfusion is dramatically reduced after donor selection, leukoreduction, and laboratory testing, some could still be present in donor's blood. A description of metagenomes in blood products eligible for transfusion represents relevant information...

journal_title：Transfusion

authors： Lau P,Cordey S,Brito F,Tirefort D,Petty TJ,Turin L,Guichebaron A,Docquier M,Zdobnov EM,Waldvogel-Abramowski S,Lecompte T,Kaiser L,Preynat-Seauve O

更新日期：2017-07-01 00:00:00

abstract：:Sera from three unrelated persons whose red cells (RBC) had the common Scianna phenotype (Sc:1,-2) contained IgG alloantibodies directed against high-frequency RBC antigens. In each case, sera or eluates or both failed to react only with Scianna null (Sc:-1,-2) cells, although an eluate from one person was compatible ...

journal_title：Transfusion

authors： Devine P,Dawson FE,Motschman TL,Skradski KJ,Orsini L,Moulds JJ,Taswell HF

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:In this study the applicability of a 16S rRNA real-time reverse transcriptase polymerase chain reaction (RT-PCR) and a Staphylococcus genus-specific PCR for screening of bacterial contamination in platelet concentrates (PCs) was determined. STUDY DESIGN AND METHODS:A total of 336 sample bags, from PCs that ...

journal_title：Transfusion

authors： Rood IG,Pettersson A,Savelkoul PH,de Korte D

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Some countries impose an upper age limit on whole blood and double RBC donation while others do not. We evaluated the safety of blood donation in older individuals (≥71 years), and their contribution to the blood supply of five countries. STUDY DESIGN AND METHODS:Twelve blood center members of the Biomedica...

journal_title：Transfusion

authors： Goldman M,Germain M,Grégoire Y,Vassallo RR,Kamel H,Bravo M,Irving DO,Di Angelantonio E,Steele WR,O'Brien SF,Biomedical Excellence for Safer Transfusion Collaborative (BEST) Investigators.

更新日期：2019-04-01 00:00:00

abstract：:White cells (WBCs) constitute a significant contaminant of platelet concentrates (PCs). Various technologies, including apheresis and filtration, are currently being developed to minimize the carryover of WBCs into platelets. The aim is to reduce contamination of less than 10(8) WBCs per platelet unit. As part of qual...

journal_title：Transfusion

authors： Marx G,Blankenfeld A,Gorodetsky R,BarShany S

更新日期：1991-10-01 00:00:00

abstract：INTRODUCTION:Frozen plasma is superior to crystalloids for hemorrhage resuscitation but remains logistically challenging in austere environments because of specialized clinical equipment for on-demand thawing. This research examines some ad hoc thawing techniques that have been implemented by military medical personnel...

journal_title：Transfusion

authors： Meledeo MA,Peltier GC,McIntosh CS,Corley JB,Bynum JA,Cap AP

更新日期：2020-06-01 00:00:00

abstract：:To determine whether chloroquine can specifically elute HLA antigens and beta 2-microglobulin (beta 2-M) from the platelet surface, quantitative immunofluorescence flow cytometry and monoclonal antibodies were used to show that HLA antigens and beta 2-M were proportionally eluted from the platelet surface without affe...

journal_title：Transfusion

authors： Kao KJ

更新日期：1988-01-01 00:00:00

abstract：:Clinical and serological data on 1435 Italian thalassemia major patients were collected during a cooperative study involving 19 centers in 10 regions. The main findings were as follows: 18 percent of the patients were under 6 years of age, 63 percent between 6 and 15, and 19 percent over 15. Forty-one percent had unde...

journal_title：Transfusion

authors： Sirchia G,Zanella A,Parravicini A,Morelati F,Rebulla P,Masera G

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Future supply with allogeneic blood transfusions faces several crucial challenges that warrant thorough (re-)evaluation of existing alternatives. Meta-analyses have indicated a significant potential for autologous blood conservation (ABC) measures to reduce the need for allogeneic blood transfusions. The qua...

journal_title：Transfusion

authors： Singbartl G,Held AL,Singbartl K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Transfusion of bacterially contaminated platelet concentrates (PCs) can result in serious health consequences for the affected patient. Before being released from blood banking facilities, PCs are routinely screened for bacterial contamination by culture-based tests. However, culture-based PC screening metho...

journal_title：Transfusion

authors： Zweitzig DR,Riccardello NM,Pester JM,Jeanmonod R,Kopnitsky MJ,O'Hara SM

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The potential hemostatic effect of infusible platelet membranes (IPM; Cyplex, Cypress Bioscience) prepared from outdated human platelets is investigated. STUDY DESIGN AND METHODS:Increasing concentrations of IPM were added to blood samples anticoagulated with low-molecular-weight heparin, in which platelets...

journal_title：Transfusion

authors： Galán AM,Bozzo J,Hernández MR,Pino M,Reverter JC,Mazzara R,Escolar G,Ordinas A

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:In spite of interventions, approximately 1000 per 1,000,000 platelet (PLT) collections are contaminated with bacteria at collection. The current prestorage culture procedure at some blood centers is to inoculate a fixed volume from the collection bag (4-8 mL) regardless of collection volume. The sensitivity ...

journal_title：Transfusion

authors： Tomasulo PA,Wagner SJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:There is growing interest in radio frequency identification (RFID) technology application for tracking blood products to achieve higher productivity and safety in the transfusion medicine supply chain. We have conducted a limited study to assess the temperature and biological effects of 13.56 MHz RF radiatio...

journal_title：Transfusion

authors： Davis R,Gottschall J,Gutierrez A,Hohberger C,Veeramani D,Holcombe J

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Unexpected neonatal alloimmune thrombocytopenia (NAIT) may have devastating consequences and its management is challenging. To design future trials, evidence from the literature and existing best practice need review. STUDY DESIGN AND METHODS:This study was a cross-sectional survey of neonatal units in Germ...

journal_title：Transfusion

authors： Bassler D,Greinacher A,Okascharoen C,Klenner A,Ditomasso J,Kiefel V,Chan A,Paes B

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The risk of transferring blood-borne infections during transfusion is continually increasing because of newly emerging and reemerging viruses. Development of a rapid screening method for emerging viruses that might be transmitted by transfusion is required to eliminate such pathogens during blood donor scree...

journal_title：Transfusion

authors： Takizawa K,Nakashima T,Mizukami T,Kuramitsu M,Endoh D,Kawauchi S,Sasaki K,Momose H,Kiba Y,Mizutani T,Furuta RA,Yamaguchi K,Hamaguchi I

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Absolute counts of CD4+ T-lymphocytes are used in the management of patients with human immunodeficiency virus infection. Low absolute counts of CD3+CD4+ cells have also been observed in healthy people--a phenomenon called idiopathic CD4 lymphocytopenia. It is common practice for normal ranges for lymphocyte...

journal_title：Transfusion

authors： Bryant JA,Wylie BR,Yuan FF,Ribeiro A,Thomson AR,Cooley MA,Fletcher A

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Drug-dependent antibodies have been associated with approximately 10% of acquired immune hemolytic anemia cases. These antibodies are a rare cause of interference in pretransfusion red blood cell (RBC) serologic testing. The aim of this work was to report three cases of subjects developing antibodies against...

journal_title：Transfusion

authors： Pham BN,Gien D,Bensaad F,Babinet J,Dubeaux I,Rouger P,Le Pennec PY

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) storage solutions work in a narrow pH range between 7.2 and 6.4. While keeping RBC within that pH range, ATP production can be increased by buffering or dilution. STUDY DESIGN AND METHODS:In the first study, 12 units of packed CP2D RBCs were pooled in groups of four, re-aliquoted, and a...

journal_title：Transfusion

authors： Hess JR,Rugg N,Joines AD,Gormas JF,Pratt PG,Silberstein EB,Greenwalt TJ

更新日期：2006-01-01 00:00:00

abstract：:Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful predictor related to outcome and prognosis. The complex pathophysiological mechanisms of the coagulopathy of TBI are multifactorial and remain still undefined. The nature of the coagulation abnormalities differs between severe TBI an...

journal_title：Transfusion

authors： Maegele M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:A novel nonenveloped single-stranded circular DNA virus (TTV) was recently identified. The prevalence of TTV in blood donors in the United States is, however, still unclear. STUDY DESIGN AND METHODS:Viral DNA was detected in US blood donors from five cities by using two sets of TTV primers: NG059/NG061/NG06...

journal_title：Transfusion

authors： Handa A,Dickstein B,Young NS,Brown KE

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Previously, we evaluated the Mirasol pathogen reduction technology (PRT) system on platelet (PLT) function before resuspension. We now evaluated this system in the presence of PLT additive solution (PAS). STUDY DESIGN AND METHODS:Double-dose PLTs (n = 15) were generated using a commercially available aphere...

journal_title：Transfusion

authors： Picker SM,Tauszig ME,Gathof BS

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:RBC components collected from donors with sickle cell trait frequently occlude WBC-reduction filters. In vitro, sickle trait RBCs have the potential for sickle Hb (Hb S) polymerization at low oxygen saturations and high Hb concentrations. STUDY DESIGN AND METHOD:To determine if the low pH and high osmolarit...

journal_title：Transfusion

authors： Stroncek DF,Rainer T,Sharon V,Byrne KM,Noguchi CT,Klein HG,Schechter AN,Leitman SF

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Presyncopal reactions are among the most common systemic reactions experienced by blood donors, occur most frequently in novice donors, and can serve as a deterrent to future donation regardless of donation experience. This report describes the validation of a presyncopal reactions scale that can be used to ...

journal_title：Transfusion

authors： France CR,Ditto B,France JL,Himawan LK

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Cryobiologic variables responsible for cell injuries and freezing techniques applicable in medical cryopractice should be revised and/or reengineered for minimizing cryoinjuries and maximizing cell recovery. In this study, the efficacy of different cryopreservation protocols based on platelet (PLT) recovery ...

journal_title：Transfusion

authors： Balint B,Paunovic D,Vucetic D,Vojvodic D,Petakov M,Trkuljic M,Stojanovic N

更新日期：2006-02-01 00:00:00