Sickle Hb polymerization in RBC components from donors with sickle cell trait prevents effective WBC reduction by filtration.

abstract：BACKGROUND:Factor (F)XIII deficiency is a rare inherited bleeding disorder, but can also be acquired due to the development of inhibitors. CASE REPORT:A 17-year-old female with systemic lupus erythematosus and end-stage kidney disease secondary to Class IV lupus nephritis developed spontaneous subcutaneous and muscula...

journal_title：Transfusion

authors： Rabik CA,Atkinson MA,Sule S,Strouse JJ

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Passenger lymphocyte-mediated graft-versus-host disease (GVHD) in solid organ transplantation (SOT-GVHD) is considered a rare complication, particularly among recipients of lung allografts. The risk of transfusion-associated GVHD (TA-GVHD) in solid organ transplants is also considered rare. The suspicion of ...

journal_title：Transfusion

authors： Pavenski K,Kamel-Reid S,Wei C,Cserti-Gazdewich CM

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) product wastage in hospitals is reported to range from 0.1% to 6.7%. Wastage at our institution averaged 4.4% of 63,000 issued RBC products. Data indicated that approximately 87% of wasted RBC units were either individual units that were out of blood bank for more than 30 minutes (dispen...

journal_title：Transfusion

authors： Heitmiller ES,Hill RB,Marshall CE,Parsons BJ,Berkow LC,Barrasso CA,Zink EK,Ness PM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Donor WBCs are responsible for numerous transfusion complications, but little is known concerning the natural history of their clearance following transfusion or of their function in the recipient's circulation. A murine transfusion model was developed to investigate the effects of blood component characteri...

journal_title：Transfusion

authors： Lee TH,Reed W,Mangawang-Montalvo L,Watson J,Busch MP

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. These studies warrant the investigation of a possible association between the ABO blood group and ferritin levels. We aimed to explore if ABO blood group is associated with iron stores expressed as fe...

journal_title：Transfusion

authors： Rigas AS,Berkfors AA,Pedersen OB,Sørensen E,Nielsen KR,Larsen MH,Paarup HM,Wandall HH,Erikstrup C,Hjalgrim H,Ullum H

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The overall number of red blood cell (RBC) units distributed to hospitals throughout the world and in the United States has decreased lately. This study was performed to determine if the number of antigen-negative RBC units distributed to hospitals has followed this trend. STUDY DESIGN AND METHODS:Stratifie...

journal_title：Transfusion

authors： Yazer MH,Anani WQ,Denomme GA,Karafin MS,Sayers M,Shaz BH,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:To estimate the impact of RBC preparations on the status of postoperative immune activation, the soluble cytokine receptors of TNFalpha (sTNF-R) and IL-2 (sIL-2R), as well as neopterin and cell-mediated lympholysis (CML), were measured. STUDY DESIGN AND METHODS:Patients undergoing strictly standardized anes...

journal_title：Transfusion

authors： Innerhofer P,Tilz G,Fuchs D,Luz G,Hobisch-Hagen P,Schobersberger W,Nussbaumer W,Lochs A,Irschick E

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:A novel WBC-reduction in-line whole-blood (WB) filter that does not retain platelets was evaluated to assess the filtration performance and, after processing WB by the platelet-rich plasma (PRP) method, to analyze the storage quality of filtered platelet concentrate (PC) units. STUDY DESIGN AND METHODS:To a...

journal_title：Transfusion

authors： Lozano ML,Pérez-Ceballos E,Rivera J,Paunovic D,Candela MJ,Vicente V

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Parvovirus B19 (B19) is known to cause a variety of human diseases in susceptible individuals by close contact via the respiratory route or by transfusion of contaminated blood or blood products. In this study, whether a case of B19 transmission was causally related to the infusion of implicated lots of a so...

journal_title：Transfusion

authors： Wu CG,Mason B,Jong J,Erdman D,McKernan L,Oakley M,Soucie M,Evatt B,Yu MY

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Low-titer group O whole blood (LTOWB) is increasingly being used in the civilian trauma setting, although there is a risk of hemolysis. This study evaluated the impact on hemolytic markers following the transfusion of 4 or more units of uncrossmatched LTOWB. METHODS:Civilian adult trauma patients who receiv...

journal_title：Transfusion

authors： Harrold IM,Seheult JN,Alarcon LH,Corcos A,Sperry JL,Triulzi DJ,Yazer MH

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The RHD gene is flanked by two highly homologous DNA segments of approximately 9000 bp, the upstream and downstream Rhesus boxes. In haplotypes with an RHD deletion, the fusion of the two Rhesus boxes generates the single-hybrid Rhesus box, the detection of which has been applied for RHD zygosity determinati...

journal_title：Transfusion

authors： Wagner FF,Moulds JM,Flegel WA

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Blood transfusions carry the risk of transmitting infections. This risk has been studied in detail in high-income countries but not in sub-Saharan Africa. This study estimates the risks of acquiring human immunodeficiency virus (HIV), hepatitis B virus (HBV), or hepatitis C virus (HCV) from a single unit of ...

journal_title：Transfusion

authors： Jayaraman S,Chalabi Z,Perel P,Guerriero C,Roberts I

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The diagnosis of immune thrombocytopenic purpura (ITP) is a diagnosis of exclusion, as stated by international guidelines. Nevertheless, the assessment of platelet (PLT) antibodies has been reported as helpful for the diagnosis and the follow-up of ITP patients. PLT antibodies are detected by highly speciali...

journal_title：Transfusion

authors： Hézard N,Simon G,Macé C,Jallu V,Kaplan C,Nguyen P

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:There has been controversy over whether HLA alloimmunization is a risk factor for platelet (PLT) transfusion refractoriness (PTR) in hematopoietic peripheral blood progenitor cell transplantation (HPBPCT). STUDY DESIGN AND METHODS:Reported here is a boy with relapsed leukemia who developed fatal PTR after a...

journal_title：Transfusion

authors： Nakazawa Y,Saito S,Hasegawa Y,Yanagisawa R,Sakashita K,Kamijo T,Miyazaki T,Sato S,Ikeda H,Ikebuchi K,Koike K

更新日期：2007-02-01 00:00:00

abstract：:White cells (WBCs) constitute a significant contaminant of platelet concentrates (PCs). Various technologies, including apheresis and filtration, are currently being developed to minimize the carryover of WBCs into platelets. The aim is to reduce contamination of less than 10(8) WBCs per platelet unit. As part of qual...

journal_title：Transfusion

authors： Marx G,Blankenfeld A,Gorodetsky R,BarShany S

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Chronic transfusion in sickle cell disease (SCD) remains the gold standard therapy for stroke prevention and for patients with severe disease despite adequate hydroxyurea treatment. The aim of our study was to assess the safety and efficacy of automated red blood cell exchange (aRBX) in patients with SCD pre...

journal_title：Transfusion

authors： Dedeken L,Lê PQ,Rozen L,El Kenz H,Huybrechts S,Devalck C,Diallo S,Heijmans C,Ferster A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:An ongoing issue in transfusion medicine is whether newly identified or emerging pathogens can be transmitted by transfusion. One method to study this question is through the use of a contemporary linked donor-recipient repository. STUDY DESIGN AND METHODS:The Retrovirus Epidemiology Donor Study Allogeneic ...

journal_title：Transfusion

authors： Kleinman SH,Glynn SA,Higgins MJ,Triulzi DJ,Smith JW,Nass CC,Garratty G,Murphy EL,LeParc GF,Schreiber GB,King MR,Chamberland ME,Nemo GJ

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) antigen and antibody combination assays have been launched as a cost-effective alternative to nucleic acid testing (NAT) for reducing the antibody-negative window period (WP). Later, a HCV antigen chemiluminescence immunoassay (CLIA) became available. STUDY DESIGN AND METHODS:A panel...

journal_title：Transfusion

authors： Laperche S,Nübling CM,Stramer SL,Brojer E,Grabarczyk P,Yoshizawa H,Kalibatas V,El Elkyabi M,Moftah F,Girault A,van Drimmelen H,Busch MP,Lelie N

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Successful hematopoietic stem cell transplantation using stored umbilical cord blood (CB) largely depends on cell dose and quality of CB units. The aim of this study was to assess the degree of early apoptosis, in addition to cell viability and hematopoietic potential, in umbilical CB units after storage. S...

journal_title：Transfusion

authors： Kim KM,Huh JY,Hong SS,Kang MS

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Adequate administration of Rh immune globulin requires an accurate determination of the number of D-positive cells in the circulation of D-negative women. Although several tests have been described for the detection of fetomaternal hemorrhage, there is still a need for a rapid, simple, and clinically relevan...

journal_title：Transfusion

authors： Salama A,David M,Wittmann G,Stelzer A,Dudenhausen JW

更新日期：1998-02-01 00:00:00

abstract：:Obstetric hemorrhage is a leading cause of maternal and perinatal mortality worldwide. Intraoperative blood salvage is common practice in many surgical specialties but its safety in obstetrics is questioned for concerns on the risks of contamination of recovered blood with amniotic fluid (AF) and of maternal-fetal all...

journal_title：Transfusion

authors： Liumbruno GM,Liumbruno C,Rafanelli D

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:A total of 517,072 and 399,326 consecutive donations were screened for hepatitis B virus (HBV) by individual-donation nucleic acid testing (ID-NAT) using Ultrio and Ultrio Plus assays (Novartis Diagnostics), respectively. The impact of more sensitive HBV detection by the latter assay version was established ...

journal_title：Transfusion

authors： Tsoi WC,Lelie N,Lin CK

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:A pilot study was conducted to determine the safety and feasibility of intravenous administration of autologous umbilical cord blood (CB) in young children with acquired neurologic disorders. Most CB units (CBUs) were electively stored in private CB banks. Unlike public banks, which utilize specific criteria...

journal_title：Transfusion

authors： Sun J,Allison J,McLaughlin C,Sledge L,Waters-Pick B,Wease S,Kurtzberg J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The proposal to assess the viability capabilities of platelets (PLTs) collected, treated, or stored in a developmental system against "fresh" PLTs from the same subject poses several important methodologic issues pertaining to the timing and manner of the collecting and separating the fresh PLTs. This study ...

journal_title：Transfusion

authors： AuBuchon JP,Herschel L,Roger J

更新日期：2005-07-01 00:00:00

abstract：:A stable mouse hybridoma line secreting monoclonal anti-C3d antibody (NBTS/BRIC 8) was produced. Ascitic fluid containing BRIC 8 can be used at a final dilution of 1 to 5000 to provide an excellent antiglobulin reagent when mixed with a conventional polyclonal rabbit anti-human IgG serum. ...

journal_title：Transfusion

authors： Holt PD,Donaldson C,Judson PA,Johnson P,Parsons SF,Anstee DJ

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:The quality of platelets (PLTs) stored in PLT additive solution (PAS) is dependent on the type and proportion of the used PAS. No data are available as to whether a different hold time before the addition of PAS to hyperconcentrated PLT suspensions has an impact on PLT quality. The in vitro quality between s...

journal_title：Transfusion

authors： Ringwald J,Haager B,Krex D,Zimmermann R,Strasser E,Antoon M,De Schrijver E,Eckstein R

更新日期：2006-06-01 00:00:00

abstract：:Many strains of Escherichia coli possess an antigen that reacts with naturally occurring antibodies to human red cell B antigens. The authors tested the hypothesis that the presence of naturally occurring anti-B isoagglutinins afford protection against the development of E. coli septicemia. The blood groups found in 1...

journal_title：Transfusion

authors： Wittels EG,Lichtman HC

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Allogeneic blood cell transplantation is a new alternative to bone marrow transplantation. Preliminary data suggest that granulocyte-colony-stimulating factor (G-CSF)-mobilized peripheral blood progenitor cells from normal donors can provide rapid hematopoietic engraftment without significant increases in tr...

journal_title：Transfusion

authors： Weinthal JA,Nemunaitis JJ,Aston S,Magsamen MJ,Rosenfeld CS

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Hemorrhage is the leading cause of death on the battlefield. Damage control resuscitation guidelines in the US military recommend whole blood as the preferred resuscitation product. The Armed Services Blood Program (ASBP) has initiated low-titer group O whole blood (LTOWB) production and predeployment donor ...

journal_title：Transfusion

authors： Taylor AL,Corley JB,Swingholm MT,Sloan MA,McDonald H Jr,Quesada JF,Evans CL,Ceballos WA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a severe disorder affecting the microcirculation of multiple organs due to a systemic endothelial cell injury secondary to a deficiency in ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13) activity. TTP is a rare complication...

journal_title：Transfusion

authors： Gasparri ML,Bellati F,Brunelli R,Perrone G,Pecorini F,Papadia A,Meloni G,Trisolini SM,Gozzer M,Domenici L,Lecce F,Benedetti Panici P

更新日期：2015-10-01 00:00:00