The RADAR repository: a resource for studies of infectious agents and their transmissibility by transfusion.

abstract：BACKGROUND:Bartonella spp. are neglected fastidious Gram-negative bacilli. We isolated Bartonella henselae from 1.2% of 500 studied blood donors and demonstrated that the bacteria remain viable in red blood cell units after 35 days of experimental infection. Now, we aim to evaluate the possibility of B. henselae transm...

journal_title：Transfusion

authors： Silva MN,Vieira-Damiani G,Ericson ME,Gupta K,Gilioli R,de Almeida AR,Drummond MR,Lania BG,de Almeida Lins K,Soares TC,Velho PE

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The temporal pattern of the biologic mechanism linking red blood cell (RBC) storage duration with clinical outcomes is yet unknown. This study investigates how such a temporal pattern can affect the power of randomized controlled trials (RCT) to detect a relevant clinical outcome mediated by the transfusion ...

journal_title：Transfusion

authors： Pereira A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The ABO system is of fundamental importance in the fields of transfusion and transplantation and has apparent associations with certain diseases, including cardiovascular disorders. ABO expression is reduced in the late phase of erythroid differentiation in vitro, whereas histone deacetylase inhibitors (HDAC...

journal_title：Transfusion

authors： Takahashi Y,Kubo R,Sano R,Nakajima T,Takahashi K,Kobayashi M,Handa H,Tsukada J,Kominato Y

更新日期：2017-03-01 00:00:00

abstract：:The authors describe a method for freezing large amounts of peripheral blood lymphocytes (PBL) in a 20 percent glycerol solution. Between 0.6 and 4.3 X 10(9) cells in autologous plasma were frozen in polyethylene freezing bags in a final volume of 50 ml. The recovery after thawing averaged 89 +/- 14 percent with a mea...

journal_title：Transfusion

authors： Areman EM,Simonis TB,Carter CS,Read EJ,Klein HG

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:The FDA requirement for sensitivity of viral NAT methods used in blood screening is a 95-percent detection limit of 100 copies per mL, whereas the NAT screening system should have a sensitivity of at least 5000 copies per mL per individual donation. According to the Common Technical Specifications of the Eur...

journal_title：Transfusion

authors： Lelie PN,van Drimmelen HA,Cuypers HT,Best SJ,Stramer SL,Hyland C,Allain JP,Moncharmont P,Defer C,Nübling M,Glauser A,da Silva Cardoso M,Viret JF,Lankinen MH,Grillner L,Wirthmüller U,Coste J,Schottstedt V,Masecar B,D

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Posttransfusion graft-versus-host disease (PT-GVHD) is underdiagnosed and underreported. Risk factors predisposing to PT-GVHD in newborn recipients, the clinical manifestations of the disease in newborns, and its mechanism are not well characterized. STUDY DESIGN AND METHODS:A literature review identified 2...

journal_title：Transfusion

authors： Ohto H,Anderson KC

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:To count extremely low levels of white cells (WBCs) in WBC-reduced blood components, a larger volume of sample must be processed. The goal was to develop an all-purpose method for concentrating the samples obtained from WBC-reduced red cells or platelets. The method was designed to be compatible with a varie...

journal_title：Transfusion

authors： Szuflad P,Dzik WH

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Epitopes of blood group A antigen can be enzymatically cleaved from red cells (RBCs), but the extent of cleavage required for normal survival in allogeneic blood transfusion recipients is unknown. Therefore, the cleavage rates were studied for A antigen epitope binding of 1) complement-activating anti-A, 2) ...

journal_title：Transfusion

authors： Hoskins LC,Larson G,Naff GB

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Bacterial contamination of blood components remains a major cause of sepsis in transfusion medicine. Between 2006 and 2010 in the 5 years before the introduction of bacterial screening of platelet (PLT) components by National Health Service Blood and Transplant (NHSBT), seven cases of PLT component-associate...

journal_title：Transfusion

authors： McDonald C,Allen J,Brailsford S,Roy A,Ball J,Moule R,Vasconcelos M,Morrison R,Pitt T

更新日期：2017-05-01 00:00:00

abstract：:Obstetric hemorrhage is a leading cause of maternal and perinatal mortality worldwide. Intraoperative blood salvage is common practice in many surgical specialties but its safety in obstetrics is questioned for concerns on the risks of contamination of recovered blood with amniotic fluid (AF) and of maternal-fetal all...

journal_title：Transfusion

authors： Liumbruno GM,Liumbruno C,Rafanelli D

更新日期：2011-10-01 00:00:00

abstract：:Most patients who need peripheral blood stem cell transplantation do not have peripheral venous access that would allow apheresis for stem cell collection. Subclavian apheresis catheters have an unacceptably high incidence of thrombosis-related access failure. A technique has been developed for translumbar placement o...

journal_title：Transfusion

authors： Haire WD,Lieberman RP,Lund GB,Wieczorek BM,Armitage JO,Kessinger A

更新日期：1990-07-01 00:00:00

abstract：:First described in 1907, the crossmatch has been in a constant state of modification since that time. Major milestones in the evolution of the test include demonstration of the relative importance of red blood cell typing and of the matching test, development of rapid techniques for the test, advent of high protein, a...

journal_title：Transfusion

authors： Oberman HA

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Alloimmunization against human platelet antigens (HPAs) during pregnancy is rare but can lead to severe bleeding disorders, such as fetal and neonatal alloimmune thrombocytopenia. STUDY DESIGN AND METHODS:In a cohort of 241 uncomplicated pregnancies, we investigated the immunogenicity of HPA mismatches and ...

journal_title：Transfusion

authors： Reiher VSA,Hönger G,Infanti L,Passweg JR,Hösli I,Frey BM,Gassner C,Meyer S,Buser AS,Holbro A,Schaub S

更新日期：2017-05-01 00:00:00

abstract：:Analysis of blood coagulation was done on samples of blood collected from ten donors undergoing combined platelet and leukapheresis using the Haemonetics Model 30 Blood Processor. Blood samples were obtained from the donors prior to, during, and following pheresis. Blood was also obtained from the blood-return line af...

journal_title：Transfusion

authors： Kisker CT,Strauss RG,Koepke JA,Maguire LC,Thompson JS

更新日期：1979-03-01 00:00:00

abstract：:The research process is a balance between the inherent risks of new discoveries and the risks of research participant safety. Conflicts of interest, inherent to the research process, as well as those introduced by emerging cellular therapies, have the potential to compromise safety. The relationship of trust between t...

journal_title：Transfusion

authors： Yim R

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Vitamin K is reported to begin reversing warfarin within 6 to 12 hours, but this may occur sooner. We sought to determine the rate of international normalized ratio (INR) reversal following vitamin K and relationships with dose, route, and baseline INR. METHODS:We evaluated adult patients receiving vitamin ...

journal_title：Transfusion

authors： Polito NB,Kanouse E,Jones CMC,McCann M,Refaai MA,Acquisto NM

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Conventional pretransfusion testing uses hemagglutination to ensure donor-recipient compatibility for ABO/D status and recipient alloantibodies. While screening large numbers of donor units for multiple antigens by hemagglutination is impractical, novel methods of DNA analysis permit the rapid determination ...

journal_title：Transfusion

authors： Klapper E,Zhang Y,Figueroa P,Ness P,Stubbs J,Abumuhor I,Bailey J,Epperson L,Tauscher C,Enriquez E,Hashmi G,Seul M

更新日期：2010-03-01 00:00:00

abstract：:Transfusion practices have changed dramatically in recent years as a result of the acquired immune deficiency syndrome crisis. The use of preoperative donation of autologous blood units has gained popularity. Healthy individuals tolerate phlebotomy well, experiencing a 2- to 5-percent incidence of vasovagal reactions....

journal_title：Transfusion

authors： Spiess BD,Sassetti R,McCarthy RJ,Narbone RF,Tuman KJ,Ivankovich AD

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:WBC reduction of cellular blood components has been introduced in many countries. Owing to concerns of residual WBCs in plasma, a new method to collect WBC-reduced plasma by apheresis was studied. STUDY DESIGN AND METHODS:An apheresis machine (PCS2, Haemonetics) was used, in combination with the "high-separ...

journal_title：Transfusion

authors： Vrielink H,van der Meer PF

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:This study evaluated the effect of routine, uncontrolled, Israeli field storage conditions on the stability and efficacy of Lyo-Plas N freeze-dried plasma (FDP). We evaluated clotting factors V, VIII, and XI; proteins S and C; fibrinogen; partial thromboplastin time (PTT); antithrombin III (ATIII); von Wille...

journal_title：Transfusion

authors： Zur M,Glassberg E,Gorenbein P,Epstein E,Eisenkraft A,Misgav M,Avramovich E

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Diclofenac has frequently been implicated as the cause of immune hemolytic anemias and less frequently of immune thrombocytopenia. The presence of the causative antibodies has only been demonstrated in patients with immune hemolytic anemia, but not yet in patients with thrombocytopenia. The cases of two pati...

journal_title：Transfusion

authors： Meyer O,Hoffmann T,Aslan T,Ahrens N,Kiesewetter H,Salama A

更新日期：2003-03-01 00:00:00

abstract：:The present study describes the use of a new polyacrolein microsphere (acrobead) protein A column. This method enables immunomodulation by the perfusion of whole blood. The efficacy of the column and its adverse effects following perfusion of blood of patients with immune thrombocytopenic purpura (ITP) or malignancies...

journal_title：Transfusion

authors： Dvilansky A,Aharon M,Riesenfeld G,Nathan I

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:We reported previously that the incidence of breakage was 34.2 percent when human RBCs were frozen with 40-percent wt/vol glycerol in polyolefin plastic bags stored in aluminum containers at -80 degrees C and subjected to transportation. When human RBCs were frozen with 40-percent wt/vol glycerol at -80 degr...

journal_title：Transfusion

authors： Valeri CR,Lane JP,Srey R,Ragno G

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:In this study the applicability of a 16S rRNA real-time reverse transcriptase polymerase chain reaction (RT-PCR) and a Staphylococcus genus-specific PCR for screening of bacterial contamination in platelet concentrates (PCs) was determined. STUDY DESIGN AND METHODS:A total of 336 sample bags, from PCs that ...

journal_title：Transfusion

authors： Rood IG,Pettersson A,Savelkoul PH,de Korte D

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:We sought to determine whether publication of blood conservation guidelines by the Society of Thoracic Surgeons in 2007 influenced transfusion rates and to understand how patient- and hospital-level factors influenced blood product usage. STUDY DESIGN AND METHODS:We identified 4,465,016 patients in the Nati...

journal_title：Transfusion

authors： Robich MP,Koch CG,Johnston DR,Schiltz N,Chandran Pillai A,Hussain ST,Soltesz EG

更新日期：2015-04-01 00:00:00

abstract：:Attention to the accurate and precise measurement of the white cell (WBC) content of transfused products has risen in response to awareness of the potential benefits of WBC-depleted components and the development of technical capabilities to produce these components. The techniques thus far reported have focused on th...

journal_title：Transfusion

authors： Dumont LJ

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:The quality of platelets (PLTs) stored in PLT additive solution (PAS) is dependent on the type and proportion of the used PAS. No data are available as to whether a different hold time before the addition of PAS to hyperconcentrated PLT suspensions has an impact on PLT quality. The in vitro quality between s...

journal_title：Transfusion

authors： Ringwald J,Haager B,Krex D,Zimmermann R,Strasser E,Antoon M,De Schrijver E,Eckstein R

更新日期：2006-06-01 00:00:00

abstract：:This paper presents recent data from quantitative and thermodynamic investigations on A and B erythrocyte antigens. In regard to weak A phenotypes on the basis of quantitative data, practically no gap is observed from the weakest Aend to the strongest A3. Weak B phenotypes give a similar distribution. However, a more ...

journal_title：Transfusion

authors： Salmon C,Lopez M,Cartron JP,Bouguerra A

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Hypoxia is a major cause of painful vaso-occlusive crisis in sickle cell disease (SCD). Simple transfusion and red blood cell (RBC) exchange are commonly used as preventive therapies whose aim is to dilute hemoglobin (Hb)S-containing RBCs (SS-RBCs) with normal RBCs (AA-RBCs) to prevent sickling. We hypothesi...

journal_title：Transfusion

authors： Bourgeaux V,Hequet O,Campion Y,Delcambre G,Chevrier AM,Rigal D,Godfrin Y

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:In 1996, the Danish National Board of Health recommended hepatitis C virus (HCV) lookback to identify recipients of blood components from donors found to be positive since the implementation of anti-HCV screening in 1991. STUDY DESIGN AND METHODS:The aim was to accumulate results of the lookback at a nation...

journal_title：Transfusion

authors： Christensen PB,Groenbaek K,Krarup HB

更新日期：1999-02-01 00:00:00