Bulk cryopreservation of lymphocytes in glycerol.

abstract：BACKGROUND:Specific subsets of peripheral blood WBCs are reservoirs for infectious agents, such as CMV and EBV, and can serve as vectors for transfusion transmission of these agents. While filter WBC reduction has been used to prevent transfusion transmission of infections, its effectiveness has not been documented for...

journal_title：Transfusion

authors： Roback JD,Bray RA,Hillyer CD

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:There is little evidence to guide management of patients with acute leukemia and intracranial hemorrhage (ICH). Predictors of long-term outcome following ICH are unknown. STUDY DESIGN AND METHODS:This study included adult patients with acute leukemia and ICH over an 8-year period. The primary outcome was da...

journal_title：Transfusion

authors： Nixon S,Lieberman L,Atenafu EG,Doherty M,Murray C,Wolfe A,Brandys D,Rowland S,Kwan BY,Yu E,Lechner B,Maze D

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) storage at 0 to 4 degrees C suppresses bacterial multiplication, but induces clusters of glycoprotein (GP) Ibalpha that trigger their phagocytosis by macrophages and reduce their survival after transfusion. A method was sought that detects cold-induced changes in GPIbalpha involved in phagocyt...

journal_title：Transfusion

authors： Badlou BA,Spierenburg G,Ulrichts H,Deckmyn H,Smid WM,Akkerman JW

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Since their description in the 1970s, anti-Hr(B) (antibody against a high-prevalence Rh antigen) and anti-hr(B) (anti-e-like antibody) are still a subject of debate about representing two aspects of a global immune response or being two independent antibodies. STUDY DESIGN AND METHODS:The aim of this study ...

journal_title：Transfusion

authors： Pham BN,Peyrard T,Tourret S,Beolet M,Many H,Juszczak G,Roussel M,Kappler-Gratias S,Rouger P,Le Pennec PY

更新日期：2009-11-01 00:00:00

abstract：:The growth of Yersinia enterocolitica in AS-1 red cells was investigated so as to study the organism's proliferation kinetics and to evaluate the effect of prestorage white cell (WBC) reduction on bacterial multiplication. Twenty-four 2-unit pools of ABO-compatible whole blood were prepared and inoculated with Y. ente...

journal_title：Transfusion

authors： Buchholz DH,AuBuchon JP,Snyder EL,Kandler R,Edberg S,Piscitelli V,Pickard C,Napychank P

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Recent retrospective studies suggest myelodysplastic syndromes (MDSs) are more common than previously recognized and patients who develop transfusional dependence may be at risk for increased comorbid complications. STUDY DESIGN AND METHODS:A retrospective review was undertaken of Medicare claims focusing o...

journal_title：Transfusion

authors： Goldberg SL,Chen E,Sasane M,Paley C,Guo A,Laouri M

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:This study compared the likelihood of return to donate and donation rate ratio by age of donors at their first donation when followed up to 12 years. STUDY DESIGN AND METHODS:Donation history of two cohorts of first-time donors (those donating in 2007 and 2013) was extracted until March 2019 from Australian...

journal_title：Transfusion

authors： Priyono A,Masser BM,Dyda A,Davison TE,Irving DO,Karki S

更新日期：2020-11-12 00:00:00

abstract：:This study evaluated various algorithms for the generation of a red cell antibody identification panel by computer. The algorithms depended on schemes that optimized Fisher's exact p value for each specificity in the panel rather than using predetermined formulations of desired phenotypic combinations. Panels produced...

journal_title：Transfusion

authors： AuBuchon JP,Roberts GC

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:The RhD blood group antigen is extremely polymorphic and the DEL phenotype represents one such class of polymorphisms. The DEL phenotype prevalent in East Asian populations arises from a synonymous substitution defined as RHD*1227A. However, initially, based on genomic and cDNA studies, the genetic basis for...

journal_title：Transfusion

authors： Lopez GH,Turner RM,McGowan EC,Schoeman EM,Scott SA,O'Brien H,Millard GM,Roulis EV,Allen AJ,Liew YW,Flower RL,Hyland CA

更新日期：2018-03-01 00:00:00

abstract：:Preoperative autologous blood donation for elective surgery patients at university hospitals was underused in the past. More recently, national educational efforts have been made. To test the impact of local surgeon interviews and education, in 1988 the same local educational program was instituted at three university...

journal_title：Transfusion

authors： Toy PT,McVay PA,Strauss RG,Stehling LC,Ahn DK

更新日期：1992-07-01 00:00:00

abstract：:Each of 20 donors underwent plateletapheresis on both the CS-3000 (Fenwal) and the 2997 (IBM) blood cell separators. The same operator performed both procedures and conducted all product studies for each donor. Platelet collection efficiency was significantly greater with the 2997 (81%) than the CS-3000 (60%) (p less ...

journal_title：Transfusion

authors： Mintz PD

更新日期：1985-07-01 00:00:00

abstract：:Lyophilized factor VIII concentrates, because of their convenience, are the most commonly used products for providing antihemophilic factor to patients with hemophilia A. Heightened concerns about associated complications indicate that cryoprecipitate usage will increase in the immediate future. We present a protocol ...

journal_title：Transfusion

authors： Menitove JE,Spero JA,Richards WA,Lewis JH,Montgomery RR,Gill JC,Hasiba U,Wheeler DV,Sherwin JA,Russell-Vaskov S,Marlar RA,Maxwell NG,Aster RH

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:The FUT2 gene regulates the expression of ABH antigens in body secretions and hence controls the secretor status. It is highly polymorphic. STUDY DESIGN AND METHODS:Healthy Chinese (n = 79) and Caucasian (n = 20) subjects were recruited for this study. Lewis blood group and secretor status were determined. ...

journal_title：Transfusion

authors： Yip SP,Lai SK,Wong ML

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:The anti-CD20 monoclonal antibody rituximab has immune-modulatory effects similar to intravenous immunoglobulin (IVIG). We performed a systematic review and meta-analysis to determine the efficacy and safety of rituximab in autoimmune diseases that are also treated with IVIG. STUDY DESIGN AND METHODS:The mo...

journal_title：Transfusion

authors： MacIsaac J,Siddiqui R,Jamula E,Li N,Baker S,Webert KE,Evanovitch D,Heddle NM,Arnold DM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Standard plateletpheresis techniques and effects on platelet (PLT) donors were investigated to provide an informative basis for advancement of apheresis software. STUDY DESIGN AND METHODS:Three paired groups with 33 male and 22 female blood donors were prospectively investigated by analyzing blood counts of...

journal_title：Transfusion

authors： Strasser EF,Schuster M,Egler K,Bauer J,Weisbach V,Ringwald J,Zimmermann R,Zingsem J,Eckstein R

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Deferral for travel to malaria-endemic areas excludes many blood donors in the United States. Most transfusion-transmitted malaria is associated with lengthy residence in malaria-endemic areas rather than routine travel. This study compares the impact of existing deferral requirements to the risk that a pres...

journal_title：Transfusion

authors： Spencer B,Steele W,Custer B,Kleinman S,Cable R,Wilkinson S,Wright D

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Hemovigilance has shown that bacteria cause more fatalities than other infections together. Surveillance for detection of bacteria in platelets (PLTs) was initiated. Concomitantly, the storage period for PLTs was extended from 5 to 7 days to reduce cost. STUDY DESIGN AND METHODS:Analysis was performed of al...

journal_title：Transfusion

authors： Munksgaard L,Albjerg L,Lillevang ST,Gahrn-Hansen B,Georgsen J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:When xenotropic murine leukemia virus-related virus (XMRV) was first reported in association with chronic fatigue syndrome, it was suggested that it might offer a risk to blood safety. Thus, the prevalence of the virus among blood donors and, if present, its transmissibility by transfusion need to be defined...

journal_title：Transfusion

authors： Dodd RY,Hackett J Jr,Linnen JM,Dorsey K,Wu Y,Zou S,Qiu X,Swanson P,Schochetman G,Gao K,Carrick JM,Krysztof DE,Stramer SL

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:TRALI is a serious adverse effect of blood transfusion. There is evidence that the condition is underrecognized and underreported. STUDY DESIGN AND METHODS:This study was an observational study carried out in a single hospital. RESULTS:Eleven cases of TRALI were recognized over 12 years. In 10 cases the im...

journal_title：Transfusion

authors： Wallis JP,Lubenko A,Wells AW,Chapman CE

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Access to a safe, adequate blood supply has proven challenging in sub-Saharan Africa, where systemic deficiencies spanning policy, collections, testing, and posttransfusion surveillance have long been recognized. Progress in transfusion safety in the early 2000s was in large part due to intervention by the W...

journal_title：Transfusion

authors： Weimer A,Tagny CT,Tapko JB,Gouws C,Tobian AAR,Ness PM,Bloch EM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The usefulness of DNA genotyping for RBC antigens as a tool for the management of multiply-transfused patients with sickle cell disease (SCD) to overcome the limitations of hemagglutination assays was evaluated. STUDY DESIGN AND METHODS:Blood samples from 40 multiply-transfused SCD patients were studied by ...

journal_title：Transfusion

authors： Castilho L,Rios M,Bianco C,Pellegrino J Jr,Alberto FL,Saad ST,Costa FF

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Platelet-derived biologic response modifiers (BRMs) including RANTES and transforming growth factor (TGF)-beta1 accumulate in platelet components during storage because of platelet activation, and they may play a causative role in nonhemolytic febrile transfusion reactions. The majority of PCs with high unit...

journal_title：Transfusion

authors： Fujihara M,Ikebuchi K,Wakamoto S,Sekiguchi S

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Autoimmune hemolytic anemia (AIHA) is usually classified as either warm or cold type. During the past few decades, mixed types (Mxs) have also been described in a number of cases (6%-8% of AIHA), often without serologic data to support the diagnosis. In this study, we demonstrate that the incidence of Mx AIH...

journal_title：Transfusion

authors： Mayer B,Yürek S,Kiesewetter H,Salama A

更新日期：2008-10-01 00:00:00

abstract：:The development of a synthetic medium for platelet storage is an important goal in transfusion medicine. Its use would make large volumes of plasma available for fractionation and might improve the quality of platelets after storage. Several investigators have described successful storage in media containing acetate. ...

journal_title：Transfusion

authors： Shimizu T,Murphy S

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Used leuko-depletion filters (LDFs), containing billions of white blood cells (WBCs), are discarded. Because the steady-state blood contains low quantities of stem and progenitor cells that are retained in LDFs, the viability and the functional properties of mononuclear cells (MNCs) and CD 34+ cells recovere...

journal_title：Transfusion

authors： Ivanovic Z,Duchez P,Morgan DA,Hermitte F,Lafarge X,Chevaleyre J,Praloran V,Dazey B,Vezon G,Boiron JM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The characterization of microchimerism (MC) by gene amplification has been limited by few allogeneic markers, ascertainment bias, and assay analytic performance. To address this, a panel of 12 MC assays based on insertion-deletion (InDel) polymorphisms had been optimized. STUDY DESIGN AND METHODS:The InDel ...

journal_title：Transfusion

authors： Lee TH,Chafets DM,Reed W,Wen L,Yang Y,Chen J,Utter GH,Owings JT,Busch MP

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Human natural killer (NK) cells are thought to play a role in antiviral response and tumor immune surveillance. The molecular mechanisms of down regulation of NK-cell activity observed after red blood cell (RBC) transfusion is still undefined. STUDY DESIGN AND METHODS:Both effects of blood transfusion (ex v...

journal_title：Transfusion

authors： Ghio M,Contini P,Negrini S,Mazzei C,Zocchi MR,Poggi A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The safety of fibrin tissue adhesives has been a concern since they entered wide clinical application. Most commercially available kits contain the proteolytic inhibitor, aprotinin, to stabilize the fibrin clot. A bovine protein, this substance has an allergenic potency. CASE REPORT:This case report present...

journal_title：Transfusion

authors： Beierlein W,Scheule AM,Antoniadis G,Braun C,Schosser R

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Umbilical cord blood (UCB) can be used as hematopoietic stem cell source for transplantation. The success of a transplantation is highly correlated with the number of total nucleated cells (TNCs) and CD34+ cells in the UCB. Certain obstetric factors increase the yield of stem cells in the UCB. It is necessar...

journal_title：Transfusion

authors： Manegold G,Meyer-Monard S,Tichelli A,Pauli D,Holzgreve W,Troeger C

更新日期：2008-05-01 00:00:00