Translumbar inferior vena cava catheters: safety and efficacy in peripheral blood stem cell transplantation.

Abstract:

:Most patients who need peripheral blood stem cell transplantation do not have peripheral venous access that would allow apheresis for stem cell collection. Subclavian apheresis catheters have an unacceptably high incidence of thrombosis-related access failure. A technique has been developed for translumbar placement of permanent, subcutaneously tunneled, silicone rubber apheresis catheters into the inferior vena cava, and 40 of these catheters have been placed in 36 patients for stem cell collection. Twenty-six catheters have been left in place for venous access during the transplantation procedure. These catheters had a very low rate (2.3%) of apheresis-related related complications. Access failure was attributed to thrombosis in 10 catheters (25%) and to mechanical complications in another 9 (22%), but access was regained in all but 4 of these cases. The catheters functioned well as venous access devices during transplantation, only rarely developing complications during that time. Venograms performed at the time of removal of 16 catheters showed no case of caval occlusion. A residual fibrin sheath was found around 14 catheters. There was no clinical or computed tomographic scan evidence of bleeding after placement or removal of the catheters. Percutaneously placed, translumbar inferior vena cava apheresis catheters provide a safe and effective route for the collection of peripheral blood stem cells for transplantation, and they can be left in place for venous access during transplantation.

journal_name

Transfusion

journal_title

Transfusion

authors

Haire WD,Lieberman RP,Lund GB,Wieczorek BM,Armitage JO,Kessinger A

doi

10.1046/j.1537-2995.1990.30690333481.x

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

511-5

issue

6

eissn

0041-1132

issn

1537-2995

journal_volume

30

pub_type

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