Red cell autoantibodies in patients with acquired immune deficiency syndrome.

Abstract:

:Mild-to-profound anemia, thrombocytopenia, and rarely neutropenia have been observed in patients with the acquired immune deficiency syndrome (AIDS). To investigate a possible immune mechanism, blood samples from 28 hospitalized AIDS patients, four asymptomatic homosexual men, four homosexual men with the AIDS-related lymphadenopathy syndrome, 30 hospitalized patients with diseases other than AIDS, and 60 blood donors were tested for the presence of atypical red cell antibodies. Eighteen AIDS patients (64%) had anti-i, nine (32%) had autoanti-U, and 12 (43%) had a positive direct antiglobulin test. One asymptomatic homosexual man and three homosexual men with lymphadenopathy also had anti-i. In contrast, of the 30 patients with diseases other than AIDS and 60 donors, none had anti-U or a positive direct antiglobulin test. One patient with sickle cell disease had anti-i. The mean hemoglobin level of AIDS patients with anti-i or anti-U was significantly lower than the mean hemoglobin level of patients who did not have those antibodies.

journal_name

Transfusion

journal_title

Transfusion

authors

McGinniss MH,Macher AM,Rook AH,Alter HJ

doi

10.1046/j.1537-2995.1986.26587020112.x

subject

Has Abstract

pub_date

1986-09-01 00:00:00

pages

405-9

issue

5

eissn

0041-1132

issn

1537-2995

journal_volume

26

pub_type

杂志文章
  • Evaluation of a new polyacrolein microsphere (acrobead) protein A column: an in vitro study using the blood of patients with immune thrombocytopenia or malignancies.

    abstract::The present study describes the use of a new polyacrolein microsphere (acrobead) protein A column. This method enables immunomodulation by the perfusion of whole blood. The efficacy of the column and its adverse effects following perfusion of blood of patients with immune thrombocytopenic purpura (ITP) or malignancies...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1992.32392213802.x

    authors: Dvilansky A,Aharon M,Riesenfeld G,Nathan I

    更新日期:1992-03-01 00:00:00

  • In vivo and in vitro characteristics of double units of RBCs collected by apheresis with a single in-line WBC-reduction filter.

    abstract:BACKGROUND:A novel apheresis procedure for a blood separator (MCS+, Haemonetics) enables the collection of 2 WBC-reduced RBC units in a single donation by using one disposable set with one in-line WBC-reduction filter (RC2H, Pall Corp.). The objective of this study was to evaluate the filtration performance in connecti...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41111373.x

    authors: Bandarenko N,Rose M,Kowalsky RJ,Baston RK,Brecher ME,Elfath MD,Whitley P,Heminway M,Holme S

    更新日期:2001-11-01 00:00:00

  • Improvement of platelet storage conditions by using new polyolefin containers.

    abstract:BACKGROUND:Storage of pooled platelet concentrates (PCs) with yields above 3.0 x 10(11) platelets per unit in a 1-L PL-732 polyolefin container for 5 days often results in a drop in pH to below 6.0. Recently, new oxygen-permeable platelet containers (1-L PL-2410, 1-L and 1.5-L Compoflex) have been developed. The maxima...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1997.37597293876.x

    authors: de Wildt-Eggen J,Schrijver JG,Bouter-Valk HJ,Fijnheer R,Bins M,van Prooijen HC

    更新日期:1997-05-01 00:00:00

  • Trends in antigen-negative red blood cell distributions by racial or ethnic groups in the United States.

    abstract:BACKGROUND:The overall number of red blood cell (RBC) units distributed to hospitals throughout the world and in the United States has decreased lately. This study was performed to determine if the number of antigen-negative RBC units distributed to hospitals has followed this trend. STUDY DESIGN AND METHODS:Stratifie...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14376

    authors: Yazer MH,Anani WQ,Denomme GA,Karafin MS,Sayers M,Shaz BH,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

    更新日期:2018-01-01 00:00:00

  • Inositol hexaphosphate-loaded red blood cells prevent in vitro sickling.

    abstract:BACKGROUND:Hypoxia is a major cause of painful vaso-occlusive crisis in sickle cell disease (SCD). Simple transfusion and red blood cell (RBC) exchange are commonly used as preventive therapies whose aim is to dilute hemoglobin (Hb)S-containing RBCs (SS-RBCs) with normal RBCs (AA-RBCs) to prevent sickling. We hypothesi...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02663.x

    authors: Bourgeaux V,Hequet O,Campion Y,Delcambre G,Chevrier AM,Rigal D,Godfrin Y

    更新日期:2010-10-01 00:00:00

  • Platelet crossmatches of single-donor platelet concentrates using a latex agglutination assay.

    abstract::A latex agglutination assay was evaluated for the purpose of identifying compatible platelet donors for alloimmunized recipients. Assay reagents were prepared by adsorbing detergent-solubilized, donor-specific platelets to polystyrene latex beads. Semiquantitative results for up to 30 donors can be completed in less t...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1993.33893342745.x

    authors: Ogden DM,Asfour A,Koller C,Lichtiger B

    更新日期:1993-08-01 00:00:00

  • Trend in ABO-incompatible RBC transfusion-related fatalities reported to the FDA, 2000-2019.

    abstract:BACKGROUND:ABO-incompatible red blood cell (RBC) transfusions and acute hemolytic reactions occur infrequently, yet resultant fatalities are reported to the US Food and Drug Administration (FDA) every year. We describe a 20-year retrospective study of reported mistransfusion cases to identify temporal trends, common ca...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.16121

    authors: Storch EK,Rogerson B,Eder AF

    更新日期:2020-12-01 00:00:00

  • Sterility and quality of blood dispensed in syringes for infants.

    abstract::A unit-dose system was designed to dispense precise quantities of blood in a form ready for immediate transfusion into neonatal patients. The principles were similar to those used by pharmacies to dispense individual doses of drugs. In the blood center, the precise volume of blood ordered for a neonatal patient was as...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1986.26286152907.x

    authors: Strauss RG,Crawford GF,Elbert C,Floss AM,Liesch M

    更新日期:1986-03-01 00:00:00

  • Recruitment of unrelated persons as bone marrow donors. A preliminary experience.

    abstract::Seven hundred and sixty-three blood donors previously typed for HLA-A and B antigens were asked to consider donating bone marrow to unrelated patients for whom no HLA-matched sibling was available. Eighty-eight percent (668) indicated willingness to donate marrow, and of these, 615 (81%) participated in testing and 53...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1986.26486262736.x

    authors: McElligott MC,Menitove JE,Aster RH

    更新日期:1986-07-01 00:00:00

  • Automatic depletion with Spectra Optia allows a safe 16% reduction of red blood cell pack consumption in exchanged sickle cell anemia patients.

    abstract:BACKGROUND:Chronic red blood cell exchanges (RBCXs) are frequently used to prevent complications in patients with sickle cell anemia, but the scarcity of matched red blood cell packs (RBCPs) is a serious concern. The main goal of this study was to compare the number of RBCPs used during RBCXs between the Spectra Optia ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15188

    authors: Hequet O,Poutrel S,Connes P,Revesz D,Chelghoum Y,Kebaili K,Cannas G,Gauthier A,Guironnet-Paquet A,Vocanson M,Nicolas JF,Renoux C,Raba M,Cognasse F,Bertrand Y,Hot A,Joly P

    更新日期:2019-05-01 00:00:00

  • Toward extended phenotype matching: a new operational paradigm for the transfusion service.

    abstract:BACKGROUND:Conventional pretransfusion testing uses hemagglutination to ensure donor-recipient compatibility for ABO/D status and recipient alloantibodies. While screening large numbers of donor units for multiple antigens by hemagglutination is impractical, novel methods of DNA analysis permit the rapid determination ...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1537-2995.2009.02462.x

    authors: Klapper E,Zhang Y,Figueroa P,Ness P,Stubbs J,Abumuhor I,Bailey J,Epperson L,Tauscher C,Enriquez E,Hashmi G,Seul M

    更新日期:2010-03-01 00:00:00

  • Role of neutralizing antibodies in controlling simian foamy virus transmission and infection.

    abstract:BACKGROUND:Human infections with simian foamy viruses (SFVs) have been reported after occupational and nonoccupational exposure to infected animals and their tissues, blood, and body fluids, although there is no evidence for human-to-human transmission. We previously demonstrated SFV transmission in monkeys by blood tr...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02372.x

    authors: Williams DK,Khan AS

    更新日期:2010-01-01 00:00:00

  • Epitope mapping of antibodies directed against the human neutrophil alloantigen 3a.

    abstract:BACKGROUND:Severe transfusion-related acute lung injury is often caused by antibodies directed against the human neutrophil alloantigen (HNA)-3a. HNA-3a results from an amino acid exchange (Arg154Gln) in the first extracellular loop of the choline transporter-like protein 2 (CTL2). The characteristics of the binding do...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03115.x

    authors: Berthold T,Wesche J,Kuhnert K,Fürll B,Hippe H,Hoppen J,Reil A,Muschter S,Bux J,Greinacher A

    更新日期:2011-10-01 00:00:00

  • Neonatal alloimmune thrombocytopenia associated with maternal-fetal incompatibility for blood group B.

    abstract:BACKGROUND:Blood group A and B antigens are expressed only weakly on platelets (PLTs) of most individuals but are very strongly expressed on PLTs from approximately 1 percent of normal subjects (Type II high expressers). The implications of this trait for transfusion medicine are undefined. STUDY DESIGN AND METHODS:A ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01531.x

    authors: Curtis BR,Fick A,Lochowicz AJ,McFarland JG,Ball RH,Peterson J,Aster RH

    更新日期:2008-02-01 00:00:00

  • Demographic changes and predicting blood supply and demand in the Netherlands.

    abstract:BACKGROUND:Concerns have been raised that aging of the general population will increase the demand for blood products. Modeling can be applied to assess trends in blood demand and supply and predict how these will develop over time. STUDY DESIGN AND METHODS:We developed mathematical models to describe and predict the ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02716.x

    authors: Borkent-Raven BA,Janssen MP,Van Der Poel CL

    更新日期:2010-11-01 00:00:00

  • Primary structure of human neutrophil antigens 1a and 1b.

    abstract:BACKGROUND:Neutrophil specific Fcγ receptor IIIb (CD16b) is a low-affinity IgG receptor. Its polymorphic variants are associated with human neutrophil antigens (HNA). HNA-1a and HNA-1b differ in four amino acids. Immunization can lead to the production of alloantibodies. The exact contribution of four amino acid exchan...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15707

    authors: Sachs UJ,Radke C,Bein G,Grabowski C,Simtong P,Bux J,Bayat B,Reil A

    更新日期:2020-04-01 00:00:00

  • Large scale preparation of leukocyte concentrates and further purification of lymphocytes and granulocytes with the IBM 2991 cell processor.

    abstract::A procedure is described for the large-scale production of pure suspensions of human lymphocytes and granulocytes. Platelet-poor buffy-coats, obtained by centrifugation of six units of ABO-compatible ACD blood, were pooled and centrifuged again, resulting in a crude leukocyte concentrate containing approximately 60 pe...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1977.17578014593.x

    authors: de la Rivière AB,Verhoef-Karssen PR,de Wit JJ,Loos JA,Prins HK

    更新日期:1977-09-01 00:00:00

  • Generation of kinins during preparation and storage of whole blood-derived platelet concentrates.

    abstract:BACKGROUND:Leukoreduction of platelet (PLT) concentrates (PCs) may be associated with hypotension in recipients, and a role for bradykinin (BK)-related peptides has been proposed for this side effect. STUDY DESIGN AND METHODS:The concentration of BK and one of its vasoactive metabolites, des-arginine(9)-BK (des-Arg(9)...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01097.x

    authors: Moreau ME,Thibault L,Désormeaux A,Chagnon M,Lemieux R,Robillard P,Marceau F,Colman RW,Lepage Y,Rivard GE,Adam A

    更新日期:2007-03-01 00:00:00

  • Hematopoietic cell infusion-related adverse events in pediatric/small recipients in a prospective/multicenter study.

    abstract:BACKGROUND:Hematopoietic cell infusion-related adverse events (HCI-AEs) in hematopoietic stem cell transplantations (HSCTs) have been largely attributed to toxicity of dimethyl sulfoxide (DMSO) for cryopreservation, but HSC products also contain various cells and plasma components. Our recent prospective study of 1125 ...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/trf.15786

    authors: Ikeda K,Ohto H,Yamada-Fujiwara M,Okuyama Y,Fujiwara SI,Muroi K,Mori T,Kasama K,Kanamori H,Iseki T,Nagamura-Inoue T,Kameda K,Kanda J,Nagai K,Fujii N,Ashida T,Hirose A,Takahashi T,Minakawa K,Tanosaki R

    更新日期:2020-05-01 00:00:00

  • Parvovirus B19 transmission by a high-purity factor VIII concentrate.

    abstract:BACKGROUND:Parvovirus B19 (B19) is known to cause a variety of human diseases in susceptible individuals by close contact via the respiratory route or by transfusion of contaminated blood or blood products. In this study, whether a case of B19 transmission was causally related to the infusion of implicated lots of a so...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.04387.x

    authors: Wu CG,Mason B,Jong J,Erdman D,McKernan L,Oakley M,Soucie M,Evatt B,Yu MY

    更新日期:2005-06-01 00:00:00

  • Barriers to blood donation in African communities in Australia: the role of home and host country culture and experience.

    abstract:BACKGROUND:An influx of African migrants and refugees can strain a host country's blood services, because often migrants have unique blood needs that cannot be sourced from local donors. To increase blood donation by the new migrants, host country blood services need to understand how blood and blood donations are view...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.03053.x

    authors: Polonsky MJ,Renzaho AM,Brijnath B

    更新日期:2011-08-01 00:00:00

  • Intravenous administration of tranexamic acid effectively reduces blood loss in primary total knee arthroplasty in a 610-patient consecutive case series.

    abstract:BACKGROUND:Tranexamic acid (TXA) has been reported to demonstrate efficacy in reducing blood loss during arthroplasty procedures. STUDY DESIGN AND METHODS:This study examines the effectiveness of TXA as a central element of a patient blood management program (PBMP) by evaluating blood loss and transfusion of red blood...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13354

    authors: Pitta M,Zawadsky M,Verstraete R,Rubinstein A

    更新日期:2016-02-01 00:00:00

  • Longitudinal monitoring of WBC subsets in packed RBC units after filtration: implications for transfusion transmission of infections.

    abstract:BACKGROUND:Specific subsets of peripheral blood WBCs are reservoirs for infectious agents, such as CMV and EBV, and can serve as vectors for transfusion transmission of these agents. While filter WBC reduction has been used to prevent transfusion transmission of infections, its effectiveness has not been documented for...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40050500.x

    authors: Roback JD,Bray RA,Hillyer CD

    更新日期:2000-05-01 00:00:00

  • HPC viability measurement: trypan blue versus acridine orange and propidium iodide.

    abstract:BACKGROUND:A reliable, validated method for rapidly determining HPC viability is essential for clinical cell engineering. STUDY DESIGN AND METHODS:A fluorometric cell viability assay using acridine orange and propidium iodide (AO/PI) was compared to the current standard, trypan blue (TB) exclusion. Viable cells staine...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40060693.x

    authors: Mascotti K,McCullough J,Burger SR

    更新日期:2000-06-01 00:00:00

  • Effect of storage time and donor sex of transfused red blood cells on 1-year survival in patients undergoing cardiac surgery: an observational study.

    abstract:BACKGROUND:Red blood cell (RBC) storage lesions and RBCs from females transfused into male recipients may have adverse effects on transfusion recipients' survival. We hypothesized that the effect of donor sex and the effect of age of blood on mortality would be most apparent in cardiac surgery patients. STUDY DESIGN A...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究

    doi:10.1111/trf.13537

    authors: Desmarets M,Bardiaux L,Benzenine E,Dussaucy A,Binda D,Tiberghien P,Quantin C,Monnet E

    更新日期:2016-05-01 00:00:00

  • Prolonged platelet preservation by transient metabolic suppression.

    abstract:BACKGROUND:In this study whether metabolic suppression can be used to preserve platelet (PLT) function during prolonged storage was investigated. STUDY DESIGN AND METHODS:Washed human PLTs were incubated without glucose and with antimycin A to block energy generation. Metabolic suppressed PLTs (MSPs) were stored for 7...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.04022.x

    authors: Badlou BA,Ijseldijk MJ,Smid WM,Akkerman JW

    更新日期:2005-02-01 00:00:00

  • NBTS/BRIC 8. A monoclonal anti-C3d antibody.

    abstract::A stable mouse hybridoma line secreting monoclonal anti-C3d antibody (NBTS/BRIC 8) was produced. Ascitic fluid containing BRIC 8 can be used at a final dilution of 1 to 5000 to provide an excellent antiglobulin reagent when mixed with a conventional polyclonal rabbit anti-human IgG serum. ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1985.25385219912.x

    authors: Holt PD,Donaldson C,Judson PA,Johnson P,Parsons SF,Anstee DJ

    更新日期:1985-05-01 00:00:00

  • Evidence of acute primary occult hepatitis B virus infection in an Italian repeat blood donor.

    abstract:BACKGROUND:Preliminary evidence of cases of acute occult hepatitis B virus (HBV) infection (OBI) has been recently reported in the literature. Furthermore, OBI definition has been the object of an international consensus conference. STUDY DESIGN AND METHODS:A case of acute primary OBI was identified and followed up in...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.02041.x

    authors: Manzini P,Abate ML,Valpreda C,Milanesi P,Curti F,Rizzetto M,Smedile A

    更新日期:2009-04-01 00:00:00

  • NAT screening of blood donors for severe acute respiratory syndrome coronavirus can potentially prevent transfusion associated transmissions.

    abstract:BACKGROUND:The severe acute respiratory syndrome (SARS) was first described in February 2003. Close contact with symptomatic patients appears to be the main route of transmission, whereas blood transfusion transmission could not be ruled out. STUDY DESIGN AND METHODS:A SARS coronavirus (SARS-CoV) detection kit develop...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.03269.x

    authors: Schmidt M,Brixner V,Ruster B,Hourfar MK,Drosten C,Preiser W,Seifried E,Roth WK

    更新日期:2004-04-01 00:00:00

  • Granulocyte transfusion kinetics measured by chemiluminescence, nitroblue tetrazolium reduction, and recovery of indium-111-labeled granulocytes.

    abstract::A 20-year-old man with chronic granulomatous disease (CGD) and who was receiving granulocyte transfusions for a refractory liver abscess was studied to compare the kinetics of 111In-labeled granulocytes with those of two functional granulocyte assays, nitroblue tetrazolium reduction and chemiluminescence. Transfused g...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27187121467.x

    authors: Elliott GR,Clay ME,Mills EL,Abramson JS,McCullough J,Quie PG

    更新日期:1987-01-01 00:00:00