Automatic depletion with Spectra Optia allows a safe 16% reduction of red blood cell pack consumption in exchanged sickle cell anemia patients.

abstract：:Baboons were bled one-third of their blood volume and then transfused with an equivalent volume of compatible donor red blood cells with 160 per cent of normal 2,3-diphosphoglycerate (2,3-DPG) levels and improved capacity to release oxygen to tissue. The mixture of baboon donor-recipient red blood cells in the circula...

journal_title：Transfusion

authors： Zaroulis CG,Pivacek LE,Lowrie GB,Valeri CR

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate an iodine-based method of activating potentially harmful viruses that might be found in normal human plasma. STUDY DESIGN AND METHODS:A procedure has been developed for inactivating lipid-enveloped and non-lipid-enveloped model viruses in normal human plasma by usin...

journal_title：Transfusion

authors： Highsmith FA,Xue H,Caple M,Walthall B,Drohan WN,Shanbrom E

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Transfusion-associated Chagas' disease (TA-CD) is a worldwide problem. Measures adopted to prevent TA-CD include the clinical and serologic screening of blood donors and/or the inactivation of Trypanosoma cruzi present in collected blood, using gentian violet as the trypanocidal agent. This study investigate...

journal_title：Transfusion

authors： Moraes-Souza H,Bordin JO,Bardossy L,MacPherson DW,Blajchman MA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Iron overload is a common complication of patients with β-thalassemia major (TM). Despite the availability of three iron chelators, deferoxamine (DFO), deferiprone (DFP), and deferasirox (DFX), some patients fail to respond adequately to monotherapy with any of them. We report a case of TM who had refractory...

journal_title：Transfusion

authors： Voskaridou E,Komninaka V,Karavas A,Terpos E,Akianidis V,Christoulas D

更新日期：2014-03-01 00:00:00

abstract：:During a 22-month period, 78,000 blood donors were screened for human T-lymphotropic virus types I and II (HTLV-I/II) at Belle Bonfils Memorial Blood Center (Denver, Colorado). Positive donors and the living recipients of their previously donated blood components were evaluated for risk factors and symptoms related to...

journal_title：Transfusion

authors： Herr V,Ambruso D,Fairfax M,Neumann A,Swanson P,Lee H

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Patients with severe combined immunodeficiency (SCID) treated with allogeneic bone marrow transplantation often receive a milder conditioning regimen than patients who undergo transplantation for hematologic malignancy, and they regularly retain circulating white cells of host origin. The origin of circulati...

journal_title：Transfusion

authors： Brady KA,Cowan MJ,Leavitt AD

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:A new generation of assays for the detection of human T-lymphotropic virus types I and II (HTLV-I/II) antibodies has been released. These assays incorporate HTLV-I- and HTLV-II-specific antigens, and some are based on new assay principles. Comparative evaluation data that include these new as well as previou...

journal_title：Transfusion

authors： Andersson S,Thorstensson R,Ramirez KG,Krook A,von Sydow M,Dias F,Biberfeld G

更新日期：1999-08-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), BRIC 66 (IgM) and BRIC 111 (IgG1), were produced by immunizing mice with ovarian cyst blood group A1 glycoprotein and Tn red cells (RBCs), respectively. Their specificities were determined by inhibitions using Tn sialoglycoproteins (SGPs), mucins (armadillo [ASG] and ovine [OSG] subm...

journal_title：Transfusion

authors： King MJ,Parsons SF,Wu AM,Jones N

更新日期：1991-02-01 00:00:00

abstract：:The transfusion of red cells (RBCs) was analyzed over a 4-year period (1984-1987), during which 9596 cesarean deliveries were performed. A total of 336 patients were identified as receiving RBC transfusions during or after cesarean delivery; 747 units of RBCs were administered. The overall incidence of transfusion in ...

journal_title：Transfusion

authors： Camann WR,Datta S

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:We assessed donor return rates, donation frequency, and factors related to the evolution of ferritin levels 2 years after entering donors into a large operational study of ferritin testing. STUDY DESIGN AND METHODS:Ferritin testing was done on donors from representative clinics (n = 12,595). Low-ferritin do...

journal_title：Transfusion

authors： Goldman M,Uzicanin S,Osmond L,Yi QL,Scalia V,O'Brien SF

更新日期：2018-12-01 00:00:00

abstract：:KEY IDEAS Chimeric antigen receptor (CAR) T-cell therapy has the potential to improve the dismal outcome of patients diagnosed with acute myeloid leukemia (AML). A major challenge for CAR T-cell therapy of AML patients is identifying leukemia-specific target antigens. Immune escape through down-regulation of target an...

journal_title：Transfusion

authors： Sauer T,Rooney CM

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Unexpected neonatal alloimmune thrombocytopenia (NAIT) may have devastating consequences and its management is challenging. To design future trials, evidence from the literature and existing best practice need review. STUDY DESIGN AND METHODS:This study was a cross-sectional survey of neonatal units in Germ...

journal_title：Transfusion

authors： Bassler D,Greinacher A,Okascharoen C,Klenner A,Ditomasso J,Kiefel V,Chan A,Paes B

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Recently, long-standing elevations of soluble growth factors released from platelets (PLTs) after contact with artificial surfaces during dialysis were described. They could be jointly responsible for the high frequency of death from cardiovascular diseases in dialysis patients. There are no comparable data ...

journal_title：Transfusion

authors： Zimmermann R,Loew D,Weisbach V,Strasser E,Ringwald J,Zingsem J,Eckstein R

更新日期：2005-03-01 00:00:00

abstract：:HLA and granulocyte-specific antibodies have been implicated in the production of transfusion-related acute lung injury (TRALI). Reported here is a case that suggests that the patient's preexisting condition may play an important role in determining whether TRALI develops upon transfusion of blood products containing ...

journal_title：Transfusion

authors： Van Buren NL,Stroncek DF,Clay ME,McCullough J,Dalmasso AP

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:An ongoing issue in transfusion medicine is whether newly identified or emerging pathogens can be transmitted by transfusion. One method to study this question is through the use of a contemporary linked donor-recipient repository. STUDY DESIGN AND METHODS:The Retrovirus Epidemiology Donor Study Allogeneic ...

journal_title：Transfusion

authors： Kleinman SH,Glynn SA,Higgins MJ,Triulzi DJ,Smith JW,Nass CC,Garratty G,Murphy EL,LeParc GF,Schreiber GB,King MR,Chamberland ME,Nemo GJ

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The severity of hemolytic disease of the newborn (HDN) due to Diego(b) (Di(b)) mismatch ranges from no symptoms to severe jaundice that requires exchange transfusion (ET). The clinical significance of anti-Di(b) is incompletely recognized. CASE REPORT:A male newborn, referred with jaundice, was revealed to ...

journal_title：Transfusion

authors： Mochizuki K,Ohto H,Hirai S,Ujiie N,Amanuma F,Kikuta A,Miura S,Yasuda H,Ishijima A,Suzuki H

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Thrombocytopenia is a serious side effect following high-dose chemotherapy or whole-body irradiation. For many patients, a hematopoietic stem cell (HSC) transplant is required as part of the treatment or to restore the integrity of the hematopoietic system. In this article, we first review the origin of thro...

journal_title：Transfusion

authors： Pineault N,Boyer L

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Allogeneic blood cell transplantation is a new alternative to bone marrow transplantation. Preliminary data suggest that granulocyte-colony-stimulating factor (G-CSF)-mobilized peripheral blood progenitor cells from normal donors can provide rapid hematopoietic engraftment without significant increases in tr...

journal_title：Transfusion

authors： Weinthal JA,Nemunaitis JJ,Aston S,Magsamen MJ,Rosenfeld CS

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Anti-IH is usually a clinically insignificant antibody that may complicate a serologic workup. However, it can occasionally cause hemolysis. We report a rare case of acute hemolysis caused by anti-IH. CASE REPORT:A 60-year-old man with a long history of chronic myelomonocytic leukemia and anemia, blood grou...

journal_title：Transfusion

authors： Irani MS,Richards C

更新日期：2011-12-01 00:00:00

abstract：:Sera from three unrelated persons whose red cells (RBC) had the common Scianna phenotype (Sc:1,-2) contained IgG alloantibodies directed against high-frequency RBC antigens. In each case, sera or eluates or both failed to react only with Scianna null (Sc:-1,-2) cells, although an eluate from one person was compatible ...

journal_title：Transfusion

authors： Devine P,Dawson FE,Motschman TL,Skradski KJ,Orsini L,Moulds JJ,Taswell HF

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Patients with autoimmune lymphoproliferative syndrome (ALPS) have an autosomal dominant genetic defect that affects lymphocyte apoptosis and is associated with chronic nonmalignant lymphadenopathy, splenomegaly, and autoimmunity, particularly affecting RBCs, WBCs, and platelets. STUDY DESIGN AND METHODS:DAT...

journal_title：Transfusion

authors： Stroncek DF,Carter LB,Procter JL,Dale JK,Straus SE

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:The safety of fibrin tissue adhesives has been a concern since they entered wide clinical application. Most commercially available kits contain the proteolytic inhibitor, aprotinin, to stabilize the fibrin clot. A bovine protein, this substance has an allergenic potency. CASE REPORT:This case report present...

journal_title：Transfusion

authors： Beierlein W,Scheule AM,Antoniadis G,Braun C,Schosser R

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by maternal alloantibodies against fetal human platelet antigens (HPAs), mostly caused by anti-HPA-1a. Population-based screening for FNAIT is still a topic of debate. Logistically and financially, the major challenge for implementation is the ...

journal_title：Transfusion

authors： Winkelhorst D,Porcelijn L,Muizelaar E,Oldert G,Huiskes E,van der Schoot CE

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The von Willebrand factor (VWF)-cleaving protease, ADAMTS13, is often deficient in cases of thrombotic thrombocytopenic purpura (TTP). The primary treatment of TTP is therapeutic plasma exchange (TPE) utilizing a variety of plasma products that help restore ADAMTS13 activity. However, multiple replacement pr...

journal_title：Transfusion

authors： Scott EA,Puca KE,Pietz BC,Duchateau BK,Friedman KD

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Human immunodeficiency virus type 1 (HIV-1) subtype O infections are not reliably detected by commonly used anti-HIV-1/2 screening assays. Therefore, anti-HIV-1/2 assays have been modified to increase their sensitivity in detecting antibodies to HIV-1 subtype O. STUDY DESIGN AND METHODS:Two new anti-HIV-1/2...

journal_title：Transfusion

authors： Jongerius JM,van der Poel CL,van Loon AM,van den Akker R,Schaasberg W,van Leeuwen EF

更新日期：1997-08-01 00:00:00

abstract：:Female blood donors with low hematocrit levels detected by copper sulfate screening were selected randomly to receive either 75 mg of iron per day, as ferrous gluconate, or a calcium phosphate placebo. Their ferritin, serum iron, total iron-binding capacity, zinc protoporphyrin, and hemoglobin values, as well as their...

journal_title：Transfusion

authors： Cable RG,Morse EE,Keltonic J,Kakaiya R,Kiraly T

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:A new citrate-acetate-NaCl platelet additive solution, identified as PAS 2, was developed to prepare platelet concentrates (PCs) from pooled 0.5 CPD buffy coats (BCs). STUDY DESIGN AND METHODS:A study was undertaken to evaluate PAS 2 in vitro (n = 8) and in vivo (n = 9) against a commercially available solu...

journal_title：Transfusion

authors： van Rhenen DJ,Vermeij H,Kappers-Klunne M,Payrat JM

更新日期：1995-01-01 00:00:00

abstract：:A fluorometric assay is described for the detection of red blood cell antibodies. The assay reveals as little as 600 molecules of bound, fluoresceinated rabbit anti-human IgG antibodies per erythrocyte. Eleven patients with possible autoimmune erythrocyte disorder and negative direct antiglobulin test were studied by ...

journal_title：Transfusion

authors： Schreiber AB,Lambermont M,Strosberg AD,Wybran J

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Photochemical pathogen inactivation treatment (PCT) of plasma components with amotosalen and UVA has been implemented in Europe. To establish a postapproval safety database, an active hemovigilance (HV) program utilizing an electronic data capture system (EDCS) was initiated. STUDY DESIGN AND METHODS:The re...

journal_title：Transfusion

authors： Cazenave JP,Waller C,Kientz D,Mendel I,Lin L,Jacquet M,Propst M,Liu W,Corash L,Sundin D,Defoin L,Messe N,Osselaer JC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Sickle cell disease (SCD) is associated with hematologic complications including delayed hemolytic transfusion reactions (DHTRs) and pregnancy-related morbidity and mortality. Hyperhemolysis syndrome (HS) is the most severe form of DHTR in patients with SCD, in which both transfused and native red blood cell...

journal_title：Transfusion

authors： Vasanthamohan L,Choo S,Marshall T,Symons YT,Matsui D,Eastabrook G,Solh Z

更新日期：2020-08-26 00:00:00