Prolonged platelet preservation by transient metabolic suppression.

abstract：BACKGROUND:Mobilized blood progenitor cells rapidly reconstitute hematopoiesis in patients after dose-intensive chemotherapy. However, optimal timing and methods of mobilized blood progenitor cell collection have yet to be fully defined. STUDY DESIGN AND METHODS:The utility of large-volume leukapheresis (LVL; > 15 L b...

journal_title：Transfusion

authors： Comenzo RL,Vosburgh E,Weintraub LR,Tansan S,Arkin CF,Wright DG

更新日期：1995-06-01 00:00:00

abstract：:Donation willingness is generally high but registering with donor centers lags behind. We need to understand why and when during the life course which groups of individuals are motivated to donate. With this knowledge, we can design targeted recruitment and retention strategies and improve evidence-based donor managem...

journal_title：Transfusion

authors： Piersma TW,Merz EM

更新日期：2019-06-01 00:00:00

abstract：:Anti-D sensitized red cells were converted to stroma, either by digitonin or hypotonic lysis, and eluates prepared by the modified rapid acid-stromal method. SDS-PAGE and both rocket- and crossed-immunoelectrophoresis showed that, of the total protein content of the eluates, 11 to 25 percent was IgG, 18 to 45 percent ...

journal_title：Transfusion

authors： Rearden A,Chiu P,Elmajian D

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:The majority of reports on transfusion reactions address adult patients. Less is known about the types, incidence, and other clinical details of transfusion reactions in pediatric populations. Furthermore, to our knowledge, there have been no previous reports directly comparing these aspects between adults a...

journal_title：Transfusion

authors： Oakley FD,Woods M,Arnold S,Young PP

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The incidence of bloodborne AIDS and the total incidence of AIDS in various areas of the United States are strongly correlated. STUDY DESIGN AND METHODS:To determine whether the same held true for Western Europe, data for 1985 through 1993 from the World Health Organization's European Non-Aggregate AIDS Dat...

journal_title：Transfusion

authors： Dal Maso L,Franceschi S,Lo Re A,De Angelis V,La Vecchia C

更新日期：1997-02-01 00:00:00

abstract：:Newly prepared platelet concentrates (PC) and platelet poor plasma (PPP) stored at either room temperature (RT) or 4 C were analyzed for ammonia content initially, and after storage at 24, 48, and 72 hours. These studies demonstrate that ammonia rapidly accumulates in PC stored at RT. This accumulation appears to be t...

journal_title：Transfusion

authors： Ukrainski CT,Goldfinger D,Pomerance JJ,Lee HC,Farber S,Sanchez R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Methods that detect a child's homozygosity by examination of allelic products are insensitive for diagnosing incest because, at a given locus, a homozygous state is expected with a frequency of only 0.25 when parents are first-degree relatives. Furthermore, these methods are not specific if the population co...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA,Houtz T

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Safe, accurate methods permitting simultaneous and/or repeated measurement of red blood cell (RBC) survival (RCS) are important to investigate pathophysiology and therapy of anemia. Methods using chromium 51 ((51) Cr)-labeled RBCs are unacceptable for infants, children, and pregnant women. We report RCS meas...

journal_title：Transfusion

authors： Mock DM,Matthews NI,Zhu S,Strauss RG,Schmidt RL,Nalbant D,Cress GA,Widness JA

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Photodynamic virus inactivation of plasma with methylene blue significantly decreases the recovery of fibrinogen and coagulation factors V and VIII. Because an adequate supply of fibrinogen is essential for the therapeutic efficacy of transfused plasma in many clinical settings, it was plausible that transfu...

journal_title：Transfusion

authors： Atance R,Pereira A,Ramírez B

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:It is not known whether increasing the dose of filgrastim after mobilizing chemotherapy improves collection of peripheral blood progenitor cells (PBPC) and leads to faster hematopoietic engraftment after autologous transplantation. STUDY DESIGN AND METHODS:A randomized, open-label, multicenter trial was car...

journal_title：Transfusion

authors： André M,Baudoux E,Bron D,Canon JL,D'Hondt V,Fassotte MF,D'Hondt L,Fillet G,Humblet Y,Jerusalem G,Vermeulen P,Symann M,Beguin Y

更新日期：2003-01-01 00:00:00

abstract：:ALX148, a novel CD47 blocking agent, is in clinical development for the treatment of advanced solid tumors and lymphoma. Because CD47 is highly expressed on red blood cells (RBCs), its therapeutic blockade can potentially interfere with pretransfusion compatibility testing. This study describes the interference of ALX...

journal_title：Transfusion

authors： Kim TY,Yoon MS,Hustinx H,Sim J,Wan HI,Kim H

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:Human parvovirus B19 is a common human pathogen that causes a variety of diseases with outcomes ranging from asymptomatic to severe, especially in immunocompromised patients. The B19 virus can be transmitted via blood and/or blood products and its resistance to common viral inactivation and/or removal method...

journal_title：Transfusion

authors： Ke L,He M,Li C,Liu Y,Gao L,Yao F,Li J,Bi X,Lv Y,Wang J,Hirsch ML,Li W

更新日期：2011-09-01 00:00:00

abstract：:Three examples of an antibody defining a 'new' high frequency red blood cell antigen, Era, are described. Family studies show Era to be inherited, but the mode of inheritance may not be straightforward. ...

journal_title：Transfusion

authors： Daniels GL,Judd WJ,Moore BP,Neitzer G,Ouellet P,Plantos M,Verrette S

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:The need for blood products is constant and unremitting, yet only a small percentage of eligible individuals answer the appeal to donate. Further, most new donors never return to provide a repeat donation. The ongoing need to attract and retain new donors has led to the examination of psychosocial factors th...

journal_title：Transfusion

authors： France JL,France CR,Himawan LK

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Nucleic acid testing (NAT) for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) was introduced for blood donation screening in the United States in 1999. This study analyzes temporal trends of these two infections since NAT introduction. STUDY DESIGN AND METHODS:Donation data from 1999 to 2008...

journal_title：Transfusion

authors： Zou S,Dorsey KA,Notari EP,Foster GA,Krysztof DE,Musavi F,Dodd RY,Stramer SL

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:An ongoing issue in transfusion medicine is whether newly identified or emerging pathogens can be transmitted by transfusion. One method to study this question is through the use of a contemporary linked donor-recipient repository. STUDY DESIGN AND METHODS:The Retrovirus Epidemiology Donor Study Allogeneic ...

journal_title：Transfusion

authors： Kleinman SH,Glynn SA,Higgins MJ,Triulzi DJ,Smith JW,Nass CC,Garratty G,Murphy EL,LeParc GF,Schreiber GB,King MR,Chamberland ME,Nemo GJ

更新日期：2005-07-01 00:00:00

abstract：:Anti-PP1Pk is found in the serum of individuals of phenotype p. Recurrent first trimester miscarriages have been reported in nearly 50 percent of mothers with the p phenotype. A comparative serologic study of three p phenotype mothers is reported. The proposita had three miscarriages while her two identical twin siste...

journal_title：Transfusion

authors： Cantin G,Lyonnais J

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Full siblings were compared with half-siblings to observe how well the two relationships could be distinguished by informative tests. STUDY AND DESIGN METHODS: Parentage analysis ascertained 25 pairs of full siblings and 25 pairs of half-siblings. The pairs were then examined for the sharing of alleles at th...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA

更新日期：2000-01-01 00:00:00

abstract：:Social and economic development, along with increased health care coverage, has caused a sharp increase in the clinical demand for blood in China. Whole blood collection has increased rapidly in the past decade but has failed to keep pace with the ever-increasing demand. Overall, the country's blood safety has been im...

journal_title：Transfusion

authors： Shi L,Wang JX,Stevens L,Ness P,Shan H

更新日期：2014-02-01 00:00:00

abstract：:A prospective double-blind study compared a manual hexadimethrine bromide (Polybrene) antiglobulin antibody detection test (P-AHG) and crossmatch with the albumin-antiglobulin antibody detection test and saline-antiglobulin crossmatch routinely used in our laboratory. A total of 10,084 pretransfusion blood samples fro...

journal_title：Transfusion

authors： Mintz PD,Anderson G

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:JMH is a high-frequency red cell blood group antigen that resides on a 76- to 80-kDa glycosylphosphatidylinositol-linked protein also known as CDw108. Antibodies with JMH specificity are often autoimmune and are usually, if not always, clinically benign. Some individuals with JMH-variant antigen produce allo...

journal_title：Transfusion

authors： Mudad R,Rao N,Issitt PD,Roy RB,Combs MR,Telen MJ

更新日期：1995-11-01 00:00:00

abstract：:Autologous blood donors (ABDs) have been reported to have favorable attitudes toward returning as homologous blood donors (HBDs), but the frequency of return has not been well documented. ABDs eligible by history to be HBDs were followed at one blood center: 255 donating for elective surgery and 234 donating during pr...

journal_title：Transfusion

authors： McVay PA,Fung HC,Toy PT

更新日期：1991-02-01 00:00:00

abstract：:We observed complement (C) activation during intermittent flow apheresis procedures (Haemonetics model 30) in four subjects, two of whom developed adult respiratory distress syndrome (ARDS). Actual C3 conversion during apheresis was illustrated by the finding of significantly elevated C3d levels (p less than 0.05) and...

journal_title：Transfusion

authors： Boogaerts MA,Roelant C,Goossens W,Verwilghen RL

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:In Africa, RHD alleles have not been fully characterized. The purpose of this study was to identify inactive and active RHD alleles at the molecular level in Congolese cohorts. STUDY DESIGN AND METHODS:Blood samples were collected from people living in central Congo populated by Teke ethnic group. A total o...

journal_title：Transfusion

authors： Touinssi M,Chapel-Fernandes S,Granier T,Bokilo A,Bailly P,Chiaroni J

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Access to a safe, adequate blood supply has proven challenging in sub-Saharan Africa, where systemic deficiencies spanning policy, collections, testing, and posttransfusion surveillance have long been recognized. Progress in transfusion safety in the early 2000s was in large part due to intervention by the W...

journal_title：Transfusion

authors： Weimer A,Tagny CT,Tapko JB,Gouws C,Tobian AAR,Ness PM,Bloch EM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Viral contamination of platelet (PLT) concentrates can result in transfusion-transmitted diseases. A photochemical treatment (PCT) process with amotosalen-HCl and long-wavelength ultraviolet light (UVA), which cross-links nucleic acids, was developed to inactivate viruses and other pathogens in PLT concentra...

journal_title：Transfusion

authors： Lin L,Hanson CV,Alter HJ,Jauvin V,Bernard KA,Murthy KK,Metzel P,Corash L

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The prevalence of hepatitis G virus (HGV) and its strain variant, the GB agent (GBV-C) is high in non-virus-inactivated plasma products, but, persistent infection in recipients is relatively low. STUDY DESIGN AND METHODS:Stored samples from transfusion donors and recipients in a prospective study of posttra...

journal_title：Transfusion

authors： Wang JT,Chen PJ,Liu DP,Sheu JC,Wang TH,Chen DS

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Thrombotic thrombocytopenic purpura (TTP) is a severe disorder affecting the microcirculation of multiple organs due to a systemic endothelial cell injury secondary to a deficiency in ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13) activity. TTP is a rare complication...

journal_title：Transfusion

authors： Gasparri ML,Bellati F,Brunelli R,Perrone G,Pecorini F,Papadia A,Meloni G,Trisolini SM,Gozzer M,Domenici L,Lecce F,Benedetti Panici P

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Our blood bank is part of a large academic institution with an active sickle cell anemia program. We provide sickle patients with blood phenotypically matched for C/c, E/e, and K antigens. Since licensed reagents are available for phenotyping C/c, E/e, and K on an automated blood analyzer, we decided to eval...

journal_title：Transfusion

authors： Le N,Harach ME,Kay JK,Brown RP,Everetts JN,Herman JH

更新日期：2014-02-01 00:00:00

abstract：:Pyruvate was placed in experimental CPD-adenine (0.25 mM) blood preservative mixtures in four concentrations ranging from 40 to 320 mM. In the 320 mM pyruvate preservative, 2,3-DPG levels were elevated above normal for six weeks of whole blood storage at 4 C. The lower pyruvate concentrations maintained elevated or no...

journal_title：Transfusion

authors： Dawson RB,Hershey RT,Myers CS

更新日期：1980-03-01 00:00:00