Abstract:
:Three cases of IgA kappa cold agglutinins (CAs) were studied. One had anti-Pr1 specificity, one had anti-Pra, and one had anti-Sa. The CAs recognize O-glycans of glycophorins. The findings supplement previous data on anti-Pr1 specificities of four IgA kappa CAs. Because all IgA kappa CAs described recognize O-glycans of glycophorins, a close association between the CA IgA isotype and specificities for O-glycans becomes apparent. It is unlikely, however, that the striking association reflects interrelations between IgA CA structure and specificity, because anti-Sa specificity and all anti-Pr subspecificities were originally defined with IgM CAs.
journal_name
Transfusionjournal_title
Transfusionauthors
Roelcke D,Hack H,Kreft H,MacDonald B,Pereira A,Habibi Bdoi
10.1046/j.1537-2995.1993.33693296808.xsubject
Has Abstractpub_date
1993-06-01 00:00:00pages
472-5issue
6eissn
0041-1132issn
1537-2995journal_volume
33pub_type
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