Abstract:
:Controversy exists about the suitability of blood from autologous donors for homologous use. We compared the infectious disease test results of 426 autologous donors, designated by donor history as suitable for homologous use, to those of 86,138 volunteer donations collected over the same 5 month period. Although donor characteristics differed, the relative risk of a positive test for anti-HBc in the autologous group was 2.09. When 413 autologous donors were compared to 413 volunteer donors matched for age, sex, and zip code, the relative risk of a positive test for anti-HBc in the autologous group was 3.2. If anti-HBc is a marker for non-A, non-B hepatitis transmissibility, then our autologous group is not as safe as our volunteer donors. We recommend that autologous blood, even when designated by donor history and laboratory screening results as suitable for homologous transfusion, not be used for other than the intended autologous recipient.
journal_name
Transfusionjournal_title
Transfusionauthors
Grossman BJ,Stewart NC,Grindon AJdoi
10.1046/j.1537-2995.1988.28388219162.xsubject
Has Abstractpub_date
1988-05-01 00:00:00pages
283-5issue
3eissn
0041-1132issn
1537-2995journal_volume
28pub_type
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