The National Marrow Donor Program.

abstract：BACKGROUND:Hemoglobin (Hb)-based oxygen (O2 ) carriers (HBOCs) are being developed as alternatives to red blood cells and blood when these products are unavailable. Clinical trials of previous HBOC generations revealed side effects, including hypertension and vasoconstriction, that were not observed in preclinical stud...

journal_title：Transfusion

authors： Muller CR,Williams AT,Munoz CJ,Eaker AM,Breton AN,Palmer AF,Cabrales P

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND:Leukoreduction of platelet (PLT) concentrates (PCs) may be associated with hypotension in recipients, and a role for bradykinin (BK)-related peptides has been proposed for this side effect. STUDY DESIGN AND METHODS:The concentration of BK and one of its vasoactive metabolites, des-arginine(9)-BK (des-Arg(9)...

journal_title：Transfusion

authors： Moreau ME,Thibault L,Désormeaux A,Chagnon M,Lemieux R,Robillard P,Marceau F,Colman RW,Lepage Y,Rivard GE,Adam A

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:The performance of the recently launched Procleix Ultrio (Chiron/Gen-Probe) human immunodeficiency virus-1 (HIV-1), hepatitis C virus (HCV), and hepatitis B virus (HBV) blood screening assay was evaluated in a European multicenter study. STUDY DESIGN AND METHODS:Serial dilutions of reference materials were ...

journal_title：Transfusion

authors： Koppelman MH,Assal A,Chudy M,Torres P,de Villaescusa RG,Reesink HW,Lelie PN,Cuypers HT

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Ultrasound-facilitated delivery of topical anesthetics has been used to achieve effective anesthesia within 5 minutes for venipuncture and the insertion of intravenous access devices, but has never been studied for blood donation. STUDY DESIGN AND METHODS:This study was a single-center, prospective, randomi...

journal_title：Transfusion

authors： Stowell CP,Trieu MQ,Chuang H,Katz N,Quarrington C

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The objective was to investigate whether women who develop preeclampsia can be identified in a routine analysis when determining fetal RHD status at 25 weeks' gestation in combination with PAPP-A levels at the first-trimester combined risk assessment for Trisomy 21. STUDY DESIGN AND METHODS:D- women partici...

journal_title：Transfusion

authors： Jakobsen TR,Clausen FB,Rode L,Dziegiel MH,Tabor A

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Uncontrollable bleeding is the leading cause of death in traumatically injured patients. The extent to which direct factor Xa inhibitors interfere with the applied resuscitation measures is presently unknown. STUDY DESIGN AND METHODS:In this study, we investigated the effect of the resuscitation fluids sali...

journal_title：Transfusion

authors： Helin TA,Zuurveld M,Manninen M,Meijers JCM,Lassila R,Brinkman HJM

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate an iodine-based method of activating potentially harmful viruses that might be found in normal human plasma. STUDY DESIGN AND METHODS:A procedure has been developed for inactivating lipid-enveloped and non-lipid-enveloped model viruses in normal human plasma by usin...

journal_title：Transfusion

authors： Highsmith FA,Xue H,Caple M,Walthall B,Drohan WN,Shanbrom E

更新日期：1994-04-01 00:00:00

abstract：:Primers based on the nucleotide sequence of the virF gene in the pYV plasmid and the chromosomal ail gene were used in polymerase chain reaction (PCR) amplifications to directly identify Yersinia enterocolitica in blood. Approximately 500 bacteria seeded into 100 microL of blood can be extracted and amplified by PCR t...

journal_title：Transfusion

authors： Feng P,Keasler SP,Hill WE

更新日期：1992-11-01 00:00:00

abstract：:Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable. HTLV screening of blood donations became mandatory in different countries to improve the safety of blood suppl...

journal_title：Transfusion

authors： Marano G,Vaglio S,Pupella S,Facco G,Catalano L,Piccinini V,Liumbruno GM,Grazzini G

更新日期：2016-01-01 00:00:00

abstract：:The possible beneficial role of white cells (WBCs) in donor blood has been investigated with respect to their capacity to remove bacteria. Preparations of buffy coat and whole blood, containing as well as reduced of WBCs, were inoculated with Staphylococcus epidermidis, S. aureus, Escherichia coli, Pseudomonas aerugin...

journal_title：Transfusion

authors： Högman CF,Gong J,Eriksson L,Hambraeus A,Johansson CS

更新日期：1991-09-01 00:00:00

abstract：:The morphology of granulocytes collected by continuous-flow centrifugation (CFC), discontinuous-flow centrifugation (DFC), and continuous-flow filtration (CFF) was investigated in 18 healthy donors by means of light microscopy and transmission electron microscopy. Light microscopy study of semithin sections of granulo...

journal_title：Transfusion

authors： Feliu E,Woessner S,Matutes E,Cardellach F,Grañena A,Marin P,Puig L,Vives-Corrons JL,Montserrat E,Rozman C

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Recently, a quasi-lipid-enveloped (LE) form of the traditionally nonlipid-enveloped (NLE) hepatitis A virus (HAV) was described in human serum and cell culture-derived HAV stocks. This discovery challenges the understanding of HAV reduction in virus clearance studies of plasma products, which were performed ...

journal_title：Transfusion

authors： Kapsch AM,Farcet MR,Antoine G,Kreil TR

更新日期：2017-06-01 00:00:00

abstract：:Donor deferral rates in regional blood centers vary from 5 to 24 per cent, reducing by more than 1,250,000 the number of units of volunteer blood available for transfusion in the nation each year. Those criteria for donor deferral which are intended to exclude donors likely to suffer a "donor reaction" are based parti...

journal_title：Transfusion

authors： Tomasulo PA,Anderson AJ,Paluso MB,Gutschenritter MA,Aster RH

更新日期：1980-09-01 00:00:00

abstract：:An antibody found in the serum of a Japanese blood donor detects a new high-frequency red cell antigen named UMC. UMC is absent from Inab phenotype cells, weakly expressed on Dr(a-) cells, and destroyed by alpha-chymotrypsin but not trypsin treatment of red cells. UMC is, therefore, a Cromer-related antigen. Immunoblo...

journal_title：Transfusion

authors： Daniels GL,Okubo Y,Yamaguchi H,Seno T,Ikuta M

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Changes within the ABO system are regularly observed phenomena in allogeneic bone marrow transplantation (BMT) and peripheral blood progenitor cell transplantation (PBPCT). Major ABO mismatch can lead to different clinical problems including acute hemolysis after infusion of the allograft, delay of red blood...

journal_title：Transfusion

authors： Scholl S,Klink A,Mügge LO,Schilling K,Höffken K,Sayer HG

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Understanding the donor base, infectious disease prevalence, and donation loss at various blood donation sites will help maximize blood collection efforts and blood availability. STUDY DESIGN AND METHODS:Using donation data collected at five US blood centers, the prevalence of HIV, HTLV, HBsAg, and HCV in f...

journal_title：Transfusion

authors： Wang B,Schreiber GB,Glynn SA,Nass CC,Smith JW,Higgins MJ,Hutching ST,Wright DJ,McEntire RL,Murphy EL,Retrovirus Epidemiology Donor Study.

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Hematopoietic cell infusion-related adverse events (HCI-AEs) in hematopoietic stem cell transplantations (HSCTs) have been largely attributed to toxicity of dimethyl sulfoxide (DMSO) for cryopreservation, but HSC products also contain various cells and plasma components. Our recent prospective study of 1125 ...

journal_title：Transfusion

authors： Ikeda K,Ohto H,Yamada-Fujiwara M,Okuyama Y,Fujiwara SI,Muroi K,Mori T,Kasama K,Kanamori H,Iseki T,Nagamura-Inoue T,Kameda K,Kanda J,Nagai K,Fujii N,Ashida T,Hirose A,Takahashi T,Minakawa K,Tanosaki R

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Autoimmune hemolytic anemia (AIHA) is usually classified as either warm or cold type. During the past few decades, mixed types (Mxs) have also been described in a number of cases (6%-8% of AIHA), often without serologic data to support the diagnosis. In this study, we demonstrate that the incidence of Mx AIH...

journal_title：Transfusion

authors： Mayer B,Yürek S,Kiesewetter H,Salama A

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Diclofenac has frequently been implicated as the cause of immune hemolytic anemias and less frequently of immune thrombocytopenia. The presence of the causative antibodies has only been demonstrated in patients with immune hemolytic anemia, but not yet in patients with thrombocytopenia. The cases of two pati...

journal_title：Transfusion

authors： Meyer O,Hoffmann T,Aslan T,Ahrens N,Kiesewetter H,Salama A

更新日期：2003-03-01 00:00:00

abstract：:A study was made of the metabolism by the rabbit of adenine administered intravenously at a dose of 35 mg/kg with 100 micronCi of 8-14C-adenine. The infused adenine was removed from the blood in two phases, first by diffusion into the tissues and second by metabolic reactions throughout the body. The adenine equilibra...

journal_title：Transfusion

authors： Bartlett GR

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Increased zinc protoporphyrin (ZPP) levels can indicate iron deficiency and may be predictive for low hemoglobin (Hb) deferral in blood donors. Prediction models for Hb deferral in whole blood donors have already been developed. In this study, we examined if addition of ZPP to these prediction models improve...

journal_title：Transfusion

authors： Baart AM,de Kort WL,Moons KG,Atsma F,Vergouwe Y

更新日期：2013-08-01 00:00:00

abstract：:Red cells from a Mexican blood donor had depressed H, IF, ID, i, Sda, Sdx, D, LW, Dib, Vel and JMH antigens. A wide range of other blood group antigens had normal activity. The unusual red cell phenotype may be caused by a membrane anomaly that alters orientation of certain cell surface components. The specificities o...

journal_title：Transfusion

authors： Biro V,Garratty G,Johnson CL,Marsh WL

更新日期：1983-01-01 00:00:00

abstract：:Cryoprecipitate is used infrequently in home therapy for patients with hemophilia A since freezer storage is required and resuspension and pooling of thawed cryoprecipitate is cumbersome. We evaluated procedures for preparation of cryoprecipitate in an "open system" so that four to six bags of cryoprecipitate could be...

journal_title：Transfusion

authors： Smith KJ,Hodges PA

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Stress-enhanced platelet (PLT) storage lesions include increased glycolysis, discoid-to-sphere morphology change, and spontaneous PLT activation. It is not clear if reduction in glycolysis can alleviate storage lesion development. STUDY DESIGN AND METHODS:Apheresis PLT concentrates were exposed to 17.2 J/mL...

journal_title：Transfusion

authors： Li J,Goodrich L,Hansen E,Edrich R,Gampp D,Goodrich RP

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Since screening for antibody to hepatitis C virus (HCV) was introduced in 1990, posttransfusion hepatitis has been reduced to nearly background levels. This has led to reconsideration of the value of testing donated blood for elevated alanine aminotransferase (ALT). The contribution of ALT testing in detecti...

journal_title：Transfusion

authors： Sankary TM,Yang G,Romeo JM,Ulrich PP,Busch MP,Rawal BD,Vyas GN

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Cryopreserved umbilical cord blood (CB) is increasingly used as a cell source to reconstitute marrow in hematopoietic stem cell transplant patients. Delays in cryopreservation may adversely affect cell viability, thereby reducing their potential for engraftment after transplantation. STUDY DESIGN AND METHOD...

journal_title：Transfusion

authors： Guttridge MG,Soh TG,Belfield H,Sidders C,Watt SM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Several drugs can cause immune hemolytic anemia. Here a patient who developed hemolytic anemia after treatment with teicoplanin is described. CASE REPORT:Owing to a two-vessel disease, a 68-year-old white man underwent coronary artery bypass grafting. He was readmitted for superficial sternal wound infectio...

journal_title：Transfusion

authors： Coluccio E,Villa MA,Villa E,Morelati F,Revelli N,Paccapelo C,Garratty G,Rebulla P

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Blood conservation strategies have been shown to be effective in decreasing red blood cell (RBC) utilization in specific patient groups. However, few data exist describing the extent of RBC transfusion reduction or their impact on transfusion practice and mortality in a diverse inpatient population. STUDY D...

journal_title：Transfusion

authors： Roubinian NH,Escobar GJ,Liu V,Swain BE,Gardner MN,Kipnis P,Triulzi DJ,Gottschall JL,Wu Y,Carson JL,Kleinman SH,Murphy EL,NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III).

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Umbilical cord blood (UCB) is a source of hematopoietic stem cells for transplantation, offering an alternative for patients unable to find a matched adult donor. UCB is also a versatile source of hematopoietic stem and progenitor cells (hCD34 + HSPCs) for research into hematologic diseases, in vitro expansi...

journal_title：Transfusion

authors： Mata MF,Hernandez D,Rologi E,Grandolfo D,Hassan E,Hua P,Kallmeier R,Hirani S,Heuts F,Tittrea V,Choo Y,Baradez MO,Watt SM,Tarunina M

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The need for blood products is constant and unremitting, yet only a small percentage of eligible individuals answer the appeal to donate. Further, most new donors never return to provide a repeat donation. The ongoing need to attract and retain new donors has led to the examination of psychosocial factors th...

journal_title：Transfusion

authors： France JL,France CR,Himawan LK

更新日期：2007-06-01 00:00:00