A modified CD34+ hematopoietic stem and progenitor cell isolation strategy from cryopreserved human umbilical cord blood.

abstract：BACKGROUND:Although the risk of transmitting infectious agents by blood transfusion is dramatically reduced after donor selection, leukoreduction, and laboratory testing, some could still be present in donor's blood. A description of metagenomes in blood products eligible for transfusion represents relevant information...

journal_title：Transfusion

authors： Lau P,Cordey S,Brito F,Tirefort D,Petty TJ,Turin L,Guichebaron A,Docquier M,Zdobnov EM,Waldvogel-Abramowski S,Lecompte T,Kaiser L,Preynat-Seauve O

更新日期：2017-07-01 00:00:00

abstract：:The development of flexible plastic blood bags has permitted effective blood component production and therapy. However, the plasticizer di(2-ethylhexyl)phthalate (DEHP), whose toxicity in humans is still undefined, is known to leach from the plastic into stored blood. Despite the availability of bags made of plastics ...

journal_title：Transfusion

authors： Rock G,Tocchi M,Ganz PR,Tackaberry ES

更新日期：1984-11-01 00:00:00

abstract：:Standard packed red cell (PRC) units can be depleted of leukocytes and platelets if they are transfused through a blood administration set in which the usual 170-mu filter has been replaced by a leukocyte removal filter (Sepacell R-500). During a 6-month period, 1550 PRC units were transfused through this filter in 61...

journal_title：Transfusion

authors： Sirchia G,Rebulla P,Parravicini A,Carnelli V,Gianotti GA,Bertolini F

更新日期：1987-09-01 00:00:00

abstract：:An example of anti-Cob which caused an acute hemolytic transfusion reaction is reported. Immunohematologic studies showed this antibody to be an IgG immunoglobulin that weakly bound complement and reacted in the antiglobulin phase of the crossmatch. The unit of whole blood implicated in the hemolytic transfusion react...

journal_title：Transfusion

authors： Lee EL,Bennett C

更新日期：1982-03-01 00:00:00

abstract：:Four commercial test kits for detecting cytomegalovirus (CMV) antibodies (indirect hemagglutination assay, indirect fluorescent antibody technique, enzyme immunoassay, and passive latex agglutination technique) were compared according to their technical demand, hands-on time, turnaround time, concordance with other te...

journal_title：Transfusion

authors： Feng CS,Williams IB,Gohd RS,Causey AP

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Avoiding immunization with clinically important antibodies is a primary objective in transfusion medicine. Therefore, it is central to identify the extent of D antigens that escape routine RhD typing of blood donors and to improve methodology if necessary. STUDY DESIGN AND METHODS:We screened 5058 D- donors...

journal_title：Transfusion

authors： Krog GR,Clausen FB,Berkowicz A,Jørgensen L,Rieneck K,Nielsen LK,Dziegiel MH

更新日期：2011-11-01 00:00:00

abstract：:We observed complement (C) activation during intermittent flow apheresis procedures (Haemonetics model 30) in four subjects, two of whom developed adult respiratory distress syndrome (ARDS). Actual C3 conversion during apheresis was illustrated by the finding of significantly elevated C3d levels (p less than 0.05) and...

journal_title：Transfusion

authors： Boogaerts MA,Roelant C,Goossens W,Verwilghen RL

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Volume replacement could allow the safe collection of twice the normal amount of red cells in a standard donation. Studies in small numbers of donors have shown that a temporary decrease in red cell mass is well tolerated when donors give twice the usual amount (170-225 mL) of red cells in a standard 405- to...

journal_title：Transfusion

authors： Smith KJ,James DS,Hunt WC,McDonough W,Quintana R

更新日期：1996-08-01 00:00:00

abstract：:Ultraviolet B (UVB) irradiation of platelet concentrates (PCs) may prevent the development of posttransfusion HLA alloimmunization. As irradiation performed in a blood center or a hospital will probably be associated with a variable postirradiation delay before transfusion, the ability to store PCs after UVB irradiati...

journal_title：Transfusion

authors： Snyder EL,Beardsley DS,Smith BR,Horne W,Johnson R,Wooten T,Napychank PA,Male P,Buchholz DH

更新日期：1991-07-01 00:00:00

abstract：:Controversy exists about the suitability of blood from autologous donors for homologous use. We compared the infectious disease test results of 426 autologous donors, designated by donor history as suitable for homologous use, to those of 86,138 volunteer donations collected over the same 5 month period. Although dono...

journal_title：Transfusion

authors： Grossman BJ,Stewart NC,Grindon AJ

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Optimal skin disinfection ensures blood safety. In this study, efficacies of the two-step skin disinfection methods used at Canadian Blood Services (CBS) and two one-step methods produced by different manufacturers were compared. STUDY DESIGN AND METHODS:In each of the three phases of the study, two methods...

journal_title：Transfusion

authors： Ramirez-Arcos S,Goldman M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A system has been developed to inactivate a wide spectrum of blood-borne pathogens in red blood cells (RBCs) before transfusion. The system utilizes S-303 to target nucleic acids of pathogens and white blood cells. The safety of pathogen inactivated RBC was assessed using S-303-treated RBCs (S-303 RBCs) and ...

journal_title：Transfusion

authors： North A,Ciaravino V,Mufti N,Corash L

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The ABO blood group is a major determinant in living donor kidney transplantation since AB antigens are expressed on renal tissue. Little attention has been directed to the ABH-secretor status of the donor kidney. As renal tissue is capable of secreting soluble ABH antigens in secretors, we examined the infl...

journal_title：Transfusion

authors： Drexler B,Holbro A,Sigle J,Gassner C,Frey BM,Schaub S,Amico P,Plattner A,Infanti L,Menter T,Mihatsch MJ,Stern M,Buser A,Dickenmann M

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The objective was to investigate whether women who develop preeclampsia can be identified in a routine analysis when determining fetal RHD status at 25 weeks' gestation in combination with PAPP-A levels at the first-trimester combined risk assessment for Trisomy 21. STUDY DESIGN AND METHODS:D- women partici...

journal_title：Transfusion

authors： Jakobsen TR,Clausen FB,Rode L,Dziegiel MH,Tabor A

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:The relationship between length of storage of red blood cell (RBC) units and biochemical changes has been well studied, but little is known about the progression of cellular immunomodulative properties in blood recipients. This study aims to quantify in vitro T-cell activation and cytokine release by white b...

journal_title：Transfusion

authors： Karam O,Tucci M,Toledano BJ,Robitaille N,Cousineau J,Thibault L,Lacroix J,Le Deist F

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Dengue virus transmission by blood transfusion is a rarely reported event. CASE REPORT:During a dengue outbreak in São Paulo city, a regular plateletpheresis donor informed the blood bank of being diagnosed a few days after donation. The recipient was hospitalized and displayed symptoms and laboratory evide...

journal_title：Transfusion

authors： Levi JE,Nishiya A,Félix AC,Salles NA,Sampaio LR,Hangai F,Sabino EC,Mendrone A Jr

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Concerns have been raised that aging of the general population will increase the demand for blood products. Modeling can be applied to assess trends in blood demand and supply and predict how these will develop over time. STUDY DESIGN AND METHODS:We developed mathematical models to describe and predict the ...

journal_title：Transfusion

authors： Borkent-Raven BA,Janssen MP,Van Der Poel CL

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:In this study the applicability of a 16S rRNA real-time reverse transcriptase polymerase chain reaction (RT-PCR) and a Staphylococcus genus-specific PCR for screening of bacterial contamination in platelet concentrates (PCs) was determined. STUDY DESIGN AND METHODS:A total of 336 sample bags, from PCs that ...

journal_title：Transfusion

authors： Rood IG,Pettersson A,Savelkoul PH,de Korte D

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Anti-Tc(a) detects a high-incidence antigen in the Cromer blood group system. Cromer system antibodies have not usually been associated with hemolytic transfusion reactions or hemolytic disease of the newborn. CASE REPORT:Anti-Tc(a) (initially identified in the patient's serum in 1982) was not detected when...

journal_title：Transfusion

authors： Kowalski MA,Pierce SR,Edwards RL,Ethirajan S,Ryan K,Livergood MP

更新日期：1999-09-01 00:00:00

abstract：:Quality control to detect inadequately deglycerolized red blood cells can be easily and inexpensively accomplished by suspending the deglycerolized cells in either recipient serum or normal saline in the same way in which the routine crossmatch is performed. In vitro hemolysis is readily and consistently apparent when...

journal_title：Transfusion

authors： Silver H,Umlas J,Kenney P,Anderson J,Pina B,Cross D

更新日期：1982-05-01 00:00:00

abstract：:Red blood cells stored in saline solution for two weeks at 12 C lose some of their Fya, Fyb, and Fy3 antigenicity. At the same time substances with specific inhibitory activity against appropriate Duffy antibodies appear in the saline. Similar changes could not be recognized in time-expired commercial reagent red bloo...

journal_title：Transfusion

authors： Williams D,Johnson CL,Marsh WL

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:This study explored the effect of storing packed RBCs suspended in 200 mL of an alkaline, hypotonic, experimental additive solution (EAS 61). STUDY DESIGN AND METHODS:Packed RBC units prepared from RBCs collected from healthy donors in CPD were stored for 8 (n = 10) and 9 (n = 10) weeks under blood bank con...

journal_title：Transfusion

authors： Hess JR,Rugg N,Knapp AD,Gormas JF,Silberstein EB,Greenwalt TJ

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:For patients with thrombocytopenia without bleeding risk factors, a platelet transfusion trigger of 10 × 10(9) /L is recommended. No studies have evaluated the clinicians' decision-making process leading to trigger changes. STUDY DESIGN AND METHODS:We report on the evaluation of trigger changes and the rela...

journal_title：Transfusion

authors： Rioux-Massé B,Laroche V,Bowman RJ,Lindgren BR,Cohn CS,Pulkrabek SM,McCullough J

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Blood has been imbued with powerful connotations through history and across cultures. Currently bestowed with scientific meaning, blood nevertheless carries symbolic resonance. This study examines these representations among practitioners and sheds light on the clinical and nonclinical factors that guide blo...

journal_title：Transfusion

authors： Fortin S,Cardona LG,Latreille M,Tucci M,Lacroix J

更新日期：2016-01-01 00:00:00

abstract：:The glycerol concentration of frozen-thawed red cells must be less than 2 percent to prevent hemolysis upon transfusion. Three methods were investigated for monitoring the glycerol concentration of frozen-thawed red cells prepared by the agglomeration technique. The supernatant osmolality and glycerol concentration we...

journal_title：Transfusion

authors： Bongiovanni MB,Hughlett MA,Wurzel HA

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:TRALI is a serious adverse effect of blood transfusion. There is evidence that the condition is underrecognized and underreported. STUDY DESIGN AND METHODS:This study was an observational study carried out in a single hospital. RESULTS:Eleven cases of TRALI were recognized over 12 years. In 10 cases the im...

journal_title：Transfusion

authors： Wallis JP,Lubenko A,Wells AW,Chapman CE

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Autologous umbilical cord blood (AutoUCB) has historically been cryopreserved for potential use in hematopoietic transplantation. Increasingly, private AutoUCB banking is performed for therapies unavailable today. A Phase I trial using AutoUCB treatment for early pediatric Type 1 diabetes afforded us an oppo...

journal_title：Transfusion

authors： Rosenau EH,Sugrue MW,Haller M,Fisk D,Kelly SS,Chang M,Hou W,Eldjerou L,Slayton W,Cogle CR,Wingard JR

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Information on the probability of survival of transfused patients is needed for policy making, but there is a paucity of empirical research into this question. A Swedish population-based study reported that the 40-month posttransfusion probability of survival was 51 percent in all patients and 41 percent in ...

journal_title：Transfusion

authors： Vamvakas EC,Goldstein R

更新日期：2002-06-01 00:00:00

abstract：INTRODUCTION:There is an increasing awareness to integrate patient blood management (PBM) within routine surgical care. Limited information about the implementation of PBM in colorectal cancer surgery is available. This is curious, as preoperative anemia, associated with increased morbidity, is highly prevalent in colo...

journal_title：Transfusion

authors： Wilson MJ,Koopman-van Gemert AWMM,Harlaar JJ,Jeekel J,Zwaginga JJ,Schipperus M

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Platelet-derived biologic response modifiers (BRMs) including RANTES and transforming growth factor (TGF)-beta1 accumulate in platelet components during storage because of platelet activation, and they may play a causative role in nonhemolytic febrile transfusion reactions. The majority of PCs with high unit...

journal_title：Transfusion

authors： Fujihara M,Ikebuchi K,Wakamoto S,Sekiguchi S

更新日期：1999-05-01 00:00:00