Rapid estimation of the glycerol concentration of frozen-thawed red cells prepared by the agglomeration technique.

Abstract:

:The glycerol concentration of frozen-thawed red cells must be less than 2 percent to prevent hemolysis upon transfusion. Three methods were investigated for monitoring the glycerol concentration of frozen-thawed red cells prepared by the agglomeration technique. The supernatant osmolality and glycerol concentration were determined on 47 units of frozen-thawed red cells prepared by agglomeration, and were found to be linearly related (r = 0.83, p less than 0.001). The supernatant refractive index was determined on 29 of the same units. There also was a linear relationship between the refractive index and the glycerol concentration (r = 0.74, p less than 0.001). The relationships were different from those previously reported for red cells prepared by other methods. The simulated transfusion test was done on red cells from three units whose glycerol concentration had been artificially elevated. The simulated transfusion test was found to be sensitive to glycerol concentrations above 2 percent. All three of the methods evaluated can be used to estimate the glycerol concentration of frozen-thawed red cells prepared by the agglomeration technique.

journal_name

Transfusion

journal_title

Transfusion

authors

Bongiovanni MB,Hughlett MA,Wurzel HA

doi

10.1046/j.1537-2995.1983.23483276865.x

subject

Has Abstract

pub_date

1983-07-01 00:00:00

pages

313-5

issue

4

eissn

0041-1132

issn

1537-2995

journal_volume

23

pub_type

杂志文章
  • Predonation screening of blood donors with rapid tests: implementation and efficacy of a novel approach to blood safety in resource-poor settings.

    abstract:BACKGROUND:In sub-Saharan Africa, the percentage of screened blood is limited to approximately 75 percent for human immunodeficiency virus antibodies (anti-HIV), 50 percent for hepatitis B surface antigen, and 19 percent for hepatitis C virus antibodies (anti-HCV), mainly because of costs. STUDY DESIGN AND METHODS:In ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.04279.x

    authors: Owusu-Ofori S,Temple J,Sarkodie F,Anokwa M,Candotti D,Allain JP

    更新日期:2005-02-01 00:00:00

  • Multiple hemolytic transfusion reactions misinterpreted as severe vaso-occlusive crisis in a patient with sickle cell disease.

    abstract:BACKGROUND:Hemolytic transfusion reactions are a rare, yet serious complication of red blood cell (RBC) transfusion. Patients with sickle cell disease (SCD) are at an increased risk for such reactions, because they are prone to make alloantibodies against transfused RBCs, complicating this integral part of their diseas...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15010

    authors: Dean CL,Maier CL,Roback JD,Stowell SR

    更新日期:2019-02-01 00:00:00

  • A comprehensive assessment program to improve blood-administering practices using the FOCUS-PDCA model.

    abstract:BACKGROUND:The Joint Commission on the Accreditation of Healthcare Organizations requires that hospitals have a planned approach to systematically collect data on processes related to the use, ordering, and administering of blood components. This study describes how a comprehensive blood-administering assessment progra...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.03117.x

    authors: Saxena S,Ramer L,Shulman IA

    更新日期:2004-09-01 00:00:00

  • In vivo viability and functional integrity of filtered platelets.

    abstract::The in vivo viability and functional integrity of filtered platelets were compared with those of nonfiltered platelets in a controlled study. On two occasions, after template bleeding time, 14 healthy volunteers underwent plateletpheresis and received 600 mg of aspirin. Autologous 111In-labeled platelets were transfus...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1990.30891020332.x

    authors: Brecher ME,Pineda AA,Zylstra-Halling VW,Chowdhury S,Forstrom LA

    更新日期:1990-10-01 00:00:00

  • Immune-mediated pancytopenia induced by oxaliplatin: a case report.

    abstract:BACKGROUND:Drug-induced immune pancytopenia is considered an uncommon disorder. CASE REPORT:A 76-year-old woman with metastatic gastric adenocarcinoma received 15 cycles of FOLFOX-6 (oxaliplatin/folinic acid/fluorouracil) with a complete response. Upon disease progression, she was restarted on FOLFOX; during the seven...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02600.x

    authors: Fontão-Wendel R,Hoff PM,Lazar A,Freitas D,Novis Y,Patah P,Tsujita M,Balthazar A,Pierroti M,Wendel S

    更新日期:2010-07-01 00:00:00

  • Effects of Intercept pathogen reduction treatment on extended cold storage of apheresis platelets.

    abstract:BACKGROUND:Platelets pose the greatest transfusion-transmitted infectious risk among blood products. Refrigeration of platelets can mitigate bacterial contamination and extend platelet shelf life. Implementation of pathogen reduction technologies (PRTs) at blood banks has become increasingly popular to protect against ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.16096

    authors: Agey A,Reddoch-Cardenas K,McIntosh C,Sharma U,Cantu C,Cap A,Bynum J

    更新日期:2020-12-08 00:00:00

  • Investigation of whether the acute hemolysis associated with Rh(o)(D) immune globulin intravenous (human) administration for treatment of immune thrombocytopenic purpura is consistent with the acute hemolytic transfusion reaction model.

    abstract:BACKGROUND:Immune thrombocytopenic purpura and secondary thrombocytopenia patients treated with Rh(o)(D) immune globulin intravenous (human; anti-D IGIV) have experienced acute hemolysis, which is inconsistent with the typical presentation of extravascular hemolysis -- the presumed mechanism of action of anti-D IGIV. A...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.02083.x

    authors: Gaines AR,Lee-Stroka H,Byrne K,Scott DE,Uhl L,Lazarus E,Stroncek DF

    更新日期:2009-06-01 00:00:00

  • Storage of platelet concentrates after high-dose ultraviolet B irradiation.

    abstract::Ultraviolet B (UVB) irradiation of platelet concentrates (PCs) may prevent the development of posttransfusion HLA alloimmunization. As irradiation performed in a blood center or a hospital will probably be associated with a variable postirradiation delay before transfusion, the ability to store PCs after UVB irradiati...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1991.31691306243.x

    authors: Snyder EL,Beardsley DS,Smith BR,Horne W,Johnson R,Wooten T,Napychank PA,Male P,Buchholz DH

    更新日期:1991-07-01 00:00:00

  • Skin disinfection methods: prospective evaluation and postimplementation results.

    abstract:BACKGROUND:Optimal skin disinfection ensures blood safety. In this study, efficacies of the two-step skin disinfection methods used at Canadian Blood Services (CBS) and two one-step methods produced by different manufacturers were compared. STUDY DESIGN AND METHODS:In each of the three phases of the study, two methods...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1537-2995.2009.02434.x

    authors: Ramirez-Arcos S,Goldman M

    更新日期:2010-01-01 00:00:00

  • Can the interval between antibody identifications be increased for alloimmunized patients?

    abstract:BACKGROUND:New alloantibody formation is unpredictable in patients who have been previously alloimmunized. Pretransfusion testing is designed to detect these antibodies while antibody identification (ABI) techniques are designed to identify the specificity of the antibody. Pretransfusion testing intervals are prescribe...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13380

    authors: Goss C,Avecilla ST,Garbaini J,Degtyaryova D,Lo D,Chang DY,Cushing M

    更新日期:2016-02-01 00:00:00

  • Factor VIII concentrate prepared from blood donors stimulated by intranasal administration of a vasopressin analogue.

    abstract::With an interval of eight weeks between collections, blood was drawn twice from 120 blood donors. At one of the donations, 0.25 ml of synthetic vasopressin, (DDAVP, 1300 micrograms/ml), was administered intranasally 60 minutes prior to collection of the blood. No drug was given at the other donation. The yield of fact...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22382224947.x

    authors: Mikaelsson M,Nilsson IM,Vilhardt H,Wiechel B

    更新日期:1982-05-01 00:00:00

  • High-throughput HBV DNA and HCV RNA detection system using a nucleic acid purification robot and real-time detection PCR: its application to analysis of posttransfusion hepatitis.

    abstract:BACKGROUND:A high-throughput detection system was developed for HBV DNA and HCV RNA. METHODS:A combination of real-time detection PCR using an automated system (PRISM 7700, PE Biosystems, Foster City, CA) and automatic viral nucleic acid extraction (BioRobot 9604, Qiagen, Hilden, Germany) was used as the high-throughp...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00024.x

    authors: Mitsunaga S,Fujimura K,Matsumoto C,Shiozawa R,Hirakawa S,Nakajima K,Tadokoro K,Juji T

    更新日期:2002-01-01 00:00:00

  • Effects of rejuvenation and frozen storage on 42-day-old AS-3 RBCs.

    abstract:BACKGROUND:A storage period of 42 days has been approved by the FDA for RBCs stored in NUTRICEL (AS-3). This study was undertaken to provide data to the FDA about the feasibility of salvaging AS-3 RBCs at the end of their storage period by rejuvenation and freezing, and to evaluate the effect of rejuvenation on indicat...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00551.x

    authors: Lockwood WB,Hudgens RW,Szymanski IO,Teno RA,Gray AD

    更新日期:2003-11-01 00:00:00

  • The impact of universal leukodepletion of the blood supply on hemovigilance reports of posttransfusion purpura and transfusion-associated graft-versus-host disease.

    abstract:BACKGROUND:The pathogenesis of posttransfusion purpura (PTP) and transfusion-associated graft-versus-host disease (TA-GVHD) involves patient exposure to donor platelets (PLTs) and T lymphocytes, respectively, which are removed during blood component leukodepletion (LD). STUDY DESIGN AND METHODS:Reports of PTP and TA-G...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01281.x

    authors: Williamson LM,Stainsby D,Jones H,Love E,Chapman CE,Navarrete C,Lucas G,Beatty C,Casbard A,Cohen H

    更新日期:2007-08-01 00:00:00

  • Impact of a policy to permit the return of donors repeat-reactive to the Abbott PRISM antibody to hepatitis B core antigen assay.

    abstract:BACKGROUND:The expected donor loss from recent implementation of antibody to hepatitis B core antigen (anti-HBc) testing in Canada was uncertain but potentially significant based on US experience. To reduce donor loss from false-reactive tests, repeat-reactive donors without other evidence of infection were eligible to...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01973.x

    authors: O'Brien SF,Yi QL,Fan W,Fearon MA,Scalia V,Goldman M

    更新日期:2009-02-01 00:00:00

  • In vivo recovery of human platelets in severe combined immunodeficient mice as a measure of platelet damage.

    abstract:BACKGROUND:Clinical performance of human platelet (PLT) products processed or stored under novel conditions is difficult to predict based on in vitro studies alone. Recovery and survival of radiolabeled PLTs in human subjects are used as surrogate markers for PLT efficacy in development of new products. Such experiment...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01295.x

    authors: Piper JT,Gelderman MP,Vostal JG

    更新日期:2007-08-01 00:00:00

  • Identification of new KLF1 and LU alleles during the resolution of Lutheran typing discrepancies.

    abstract:BACKGROUND:The Lu(b) antigen is expressed on red blood cells (RBCs) of the majority of individuals in all populations. Its absence in transfused patients may lead to alloantibody production and mild-to-moderate transfusion reactions, and in pregnancies to mild hemolytic disease of the fetus and newborn. This report des...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13556

    authors: Garcia-Sanchez F,Pardi C,Kupatawintu P,Thornton N,Rodriguez MA,Lucea I,Sood C,Ochoa-Garay G

    更新日期:2016-06-01 00:00:00

  • A correlation between growth rate, apoptosis, and tumor necrosis factor-α in umbilical cord blood cells infected with two strains of Mycobacterium tuberculosis.

    abstract:BACKGROUND:Using umbilical cord blood (UCB) cells, it was demonstrated that three virulent isolates, two highly transmissible clinical isolates and the virulent laboratory strain, demonstrated rapid growth in the UCB cells, which was significantly faster than the growth rate observed for a unique isolate. There was als...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02187.x

    authors: Theus JW,Justus RS,Theus SA

    更新日期:2009-08-01 00:00:00

  • Comprehensive review of platelet storage methods for use in the treatment of active hemorrhage.

    abstract::This review considers the various methods currently in use, or under investigation, for the storage of platelets intended for use in the treatment of active hemorrhage. The current standard practice of storing platelets at room temperature (RT) (20°C-24°C) optimizes circulating time, but at the expense of hemostatic f...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.13504

    authors: Milford EM,Reade MC

    更新日期:2016-04-01 00:00:00

  • A comprehensive program to minimize platelet outdating.

    abstract:BACKGROUND:Platelet (PLT) transfusions are essential for patients who are bleeding or have an increased risk of bleeding due to a decreased number or abnormal function of circulating PLTs. A shelf life of 5 days for PLT products presents an inventory management challenge. In 2006, greater than 10% of apheresis PLTs mad...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.03039.x

    authors: Fuller AK,Uglik KM,Braine HG,King KE

    更新日期:2011-07-01 00:00:00

  • Evaluation of a new polyacrolein microsphere (acrobead) protein A column: an in vitro study using the blood of patients with immune thrombocytopenia or malignancies.

    abstract::The present study describes the use of a new polyacrolein microsphere (acrobead) protein A column. This method enables immunomodulation by the perfusion of whole blood. The efficacy of the column and its adverse effects following perfusion of blood of patients with immune thrombocytopenic purpura (ITP) or malignancies...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1992.32392213802.x

    authors: Dvilansky A,Aharon M,Riesenfeld G,Nathan I

    更新日期:1992-03-01 00:00:00

  • Bartonella henselae transmission by blood transfusion in mice.

    abstract:BACKGROUND:Bartonella spp. are neglected fastidious Gram-negative bacilli. We isolated Bartonella henselae from 1.2% of 500 studied blood donors and demonstrated that the bacteria remain viable in red blood cell units after 35 days of experimental infection. Now, we aim to evaluate the possibility of B. henselae transm...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13545

    authors: Silva MN,Vieira-Damiani G,Ericson ME,Gupta K,Gilioli R,de Almeida AR,Drummond MR,Lania BG,de Almeida Lins K,Soares TC,Velho PE

    更新日期:2016-06-01 00:00:00

  • Systematic sequence analysis of the human fucosyltransferase 2 (FUT2) gene identifies novel sequence variations and alleles.

    abstract:BACKGROUND:The FUT2 gene regulates the expression of ABH antigens in body secretions and hence controls the secretor status. It is highly polymorphic. STUDY DESIGN AND METHODS:Healthy Chinese (n = 79) and Caucasian (n = 20) subjects were recruited for this study. Lewis blood group and secretor status were determined. ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01280.x

    authors: Yip SP,Lai SK,Wong ML

    更新日期:2007-08-01 00:00:00

  • Adoptive therapy by transfusing expanded donor murine natural killer T cells can suppress acute graft-versus-host disease in allogeneic bone marrow transplantation.

    abstract:BACKGROUND:Invariant natural killer T cells (iNKT cells) may suppress graft-versus-host disease (GVHD) after allogeneic transplantation. The purpose of this study was to investigate the therapeutic potential of iNKT cells from major histocompatibility complex (MHC)-mismatched donors for preventing GVHD after allogeneic...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02395.x

    authors: Yang J,Gao L,Liu Y,Ren Y,Xie R,Fan H,Qian K

    更新日期:2010-02-01 00:00:00

  • A study of criteria for blood donor deferral.

    abstract::Donor deferral rates in regional blood centers vary from 5 to 24 per cent, reducing by more than 1,250,000 the number of units of volunteer blood available for transfusion in the nation each year. Those criteria for donor deferral which are intended to exclude donors likely to suffer a "donor reaction" are based parti...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1980.20581034503.x

    authors: Tomasulo PA,Anderson AJ,Paluso MB,Gutschenritter MA,Aster RH

    更新日期:1980-09-01 00:00:00

  • Preventing murine transfusion-related acute lung injury by expansion of CD4+ CD25+ FoxP3+ Tregs using IL-2/anti-IL-2 complexes.

    abstract:BACKGROUND:Transfusion-related acute lung injury (TRALI) is one of the most serious adverse events following transfusion, and there is no specific treatment in clinical practice. However, regulatory T cells (Tregs) have been suggested to play a potential role in the treatment of TRALI. This study investigated whether i...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15064

    authors: He R,Li L,Kong Y,Tian L,Tian X,Fang P,Bian M,Liu Z

    更新日期:2019-02-01 00:00:00

  • Demographic changes and predicting blood supply and demand in the Netherlands.

    abstract:BACKGROUND:Concerns have been raised that aging of the general population will increase the demand for blood products. Modeling can be applied to assess trends in blood demand and supply and predict how these will develop over time. STUDY DESIGN AND METHODS:We developed mathematical models to describe and predict the ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02716.x

    authors: Borkent-Raven BA,Janssen MP,Van Der Poel CL

    更新日期:2010-11-01 00:00:00

  • The value of transfusion of phenotyped blood units for thalassemia and sickle cell anemia patients at an academic center.

    abstract:BACKGROUND:Blood transfusion is the first-line treatment for patients with thalassemia and many sickle cell patients. However, cases of unregulated blood transfusion are shown to carry a high risk of alloimmunization to red blood cells (RBCs), which can lead to a hemolytic transfusion reaction and be fatal to patients....

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15682

    authors: Hindawi S,Badawi M,Elfayoumi R,Elgemmezi T,Al Hassani A,Raml M,Alamoudi S,Gholam K

    更新日期:2020-02-01 00:00:00

  • "Naturally-occurring" anti-K1: possible association with mycobacterium infection.

    abstract::We report a case of "naturally-occurring" (nonred blood cell stimulated) anti-K1. The patient had never received a blood transfusion. Red blood cell antibody screening panels showed agglutination with K:1 red blood cells at room temperature and not in the anti-globulin test. Testing with 2-mercaptoethanol showed the a...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1978.18478251244.x

    authors: Kanel GC,Davis I,Bowman JE

    更新日期:1978-07-01 00:00:00

  • Multicenter study to evaluate a new enumeration method for hematopoietic stem cell collection management.

    abstract:BACKGROUND:CD34 flow cytometry is the gold standard for stem cell enumeration in peripheral blood at the mobilization stage and in the final apheresis product. The new stem cell mode of the Sysmex XN Series analyzer enumerates an immature cell population in the white progenitor and pathological cell (WPC) channel, base...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究

    doi:10.1111/trf.14183

    authors: Grommé M,Russcher H,Braakman E,Klinkspoor JH,Dobber JA,de Greef I,de Wit NCJ

    更新日期:2017-08-01 00:00:00