Factor VIII concentrate prepared from blood donors stimulated by intranasal administration of a vasopressin analogue.

abstract：BACKGROUND:The RhD blood group antigen is extremely polymorphic and the DEL phenotype represents one such class of polymorphisms. The DEL phenotype prevalent in East Asian populations arises from a synonymous substitution defined as RHD*1227A. However, initially, based on genomic and cDNA studies, the genetic basis for...

journal_title：Transfusion

authors： Lopez GH,Turner RM,McGowan EC,Schoeman EM,Scott SA,O'Brien H,Millard GM,Roulis EV,Allen AJ,Liew YW,Flower RL,Hyland CA

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:In 1999, NAT of blood donations was implemented to detect "window-period" infections. Blood donors who have confirmed NAT results positive for the presence of HCV in the absence of anti-HCV are likely to have been recently infected. Of over 26.8 million donations tested between March 3, 1999, and March 31, 2...

journal_title：Transfusion

authors： Orton SL,Stramer SL,Dodd RY,Alter MJ

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Recently, long-standing elevations of soluble growth factors released from platelets (PLTs) after contact with artificial surfaces during dialysis were described. They could be jointly responsible for the high frequency of death from cardiovascular diseases in dialysis patients. There are no comparable data ...

journal_title：Transfusion

authors： Zimmermann R,Loew D,Weisbach V,Strasser E,Ringwald J,Zingsem J,Eckstein R

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Blood components are often given prophylactically before the placement of invasive lines in patients with coagulation defects. Little, however, is known about the epidemiology of defects in these patients. The purpose of this study is to ascertain what proportion of intensive care patients who receive invasi...

journal_title：Transfusion

authors： DeLoughery TG,Liebler JM,Simonds V,Goodnight SH

更新日期：1996-09-01 00:00:00

abstract：:Most patients who need peripheral blood stem cell transplantation do not have peripheral venous access that would allow apheresis for stem cell collection. Subclavian apheresis catheters have an unacceptably high incidence of thrombosis-related access failure. A technique has been developed for translumbar placement o...

journal_title：Transfusion

authors： Haire WD,Lieberman RP,Lund GB,Wieczorek BM,Armitage JO,Kessinger A

更新日期：1990-07-01 00:00:00

abstract：:The in vivo viability and functional integrity of filtered platelets were compared with those of nonfiltered platelets in a controlled study. On two occasions, after template bleeding time, 14 healthy volunteers underwent plateletpheresis and received 600 mg of aspirin. Autologous 111In-labeled platelets were transfus...

journal_title：Transfusion

authors： Brecher ME,Pineda AA,Zylstra-Halling VW,Chowdhury S,Forstrom LA

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Studies analyzing motivation factors that lead to blood donation have found altruism to be the primary motivation factor; however, social capital has not been analyzed in this context. Our study examines the association between motivation factors (altruism, self-interest, and response to direct appeal) and s...

journal_title：Transfusion

authors： Gonçalez TT,Di Lorenzo Oliveira C,Carneiro-Proietti AB,Moreno EC,Miranda C,Larsen N,Wright D,Leão S,Loureiro P,de Almeida-Neto C,Lopes MI,Proietti FA,Custer B,Sabino E,NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), I

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:At Canadian Blood Services, platelet concentrate (PC) shelf life was extended to 7 days with a large-volume, delayed-sampling bacterial screening algorithm. We present the development study and postimplementation results. STUDY DESIGN AND METHODS:In the development study, PCs inoculated with five bacteria (...

journal_title：Transfusion

authors： Ramirez-Arcos S,Evans S,McIntyre T,Pang C,Yi QL,DiFranco C,Goldman M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Dengue fever and hemorrhagic disease are caused by four dengue virus (DENV) serotypes (DENV-1 to -4), mosquito-borne flaviviruses with increasing incidence, and expanding global distributions. Documented transfusion transmission of West Nile virus raised concern regarding transfusion-transmitted DENV. METHO...

journal_title：Transfusion

authors： Linnen JM,Vinelli E,Sabino EC,Tobler LH,Hyland C,Lee TH,Kolk DP,Broulik AS,Collins CS,Lanciotti RS,Busch MP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:In cases of warm autoimmune hemolytic anemia (WAIHA), crossmatch incompatible RBCs are most often used for transfusion. The determination of the in vivo survival of transfused and autologous RBCs in WAIHA is helpful in the assessment of the efficacy of transfusion and other therapeutic interventions. CASE R...

journal_title：Transfusion

authors： Zeiler T,Müller JT,Hasse C,Kullmer J,Kretschmer V

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Health history questions are introduced into the predonation interview to identify blood donors believed to pose a higher risk of infectious diseases to recipients. This study assesses the current impact of some of those questions. STUDY DESIGN AND METHODS:Donor deferral and donation data were extracted fro...

journal_title：Transfusion

authors： Zou S,Musavi F,Notari EP 4th,Fujii KE,Dodd RY,ARCNET Study Group.

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Human T-cell lymphoma/leukemia viruses types I and II (HTLV-I and HTLV-II) are related exogenous human retroviruses. The former is definitely pathogenic while disease association with the latter is unclear. There are two subtypes of HTLV-II, A and B. Currently, enzyme-linked immunosorbent assays (ELISAs) bas...

journal_title：Transfusion

authors： Poiesz BJ,Dube S,Jones B,Bryz-Gornia V,Dean MT,Spicer T,Hengst J,Sayre K,Esteban E,Ferrer JF

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:With changing demographics of the United States population and the continuous need to recruit new donors, it is important to monitor the demographic profile of first-time donors and to evaluate changes in the donor pool to improve recruitment targeting. STUDY DESIGN AND METHODS:First-time whole blood (n = 9...

journal_title：Transfusion

authors： Wu Y,Glynn SA,Schreiber GB,Wright DJ,Lo A,Murphy EL,Kleinman SH,Garratty G,Retrovirus Epidemiology Donor Study (REDS) Group.

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:In February 2007, a 63-year-old man underwent surgery. Retrospective testing with nucleic acid testing (NAT) showed that the patient was human immunodeficiency virus Type 1 (HIV-1) positive 10 days after transfusion. The transfusion-transmitted infection had been identified by a donor-related lookback starte...

journal_title：Transfusion

authors： Schmidt M,Korn K,Nübling CM,Chudy M,Kress J,Horst HA,Geusendam G,Hennig H,Sireis W,Rabenau HF,Doerr HW,Berger A,Hourfar MK,Gubbe K,Karl A,Fickenscher H,Tischer BK,Babiel R,Seifried E,Gürtler L

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Allogeneic transfusion can result in alloimmunization, leading to platelet (PLT) refractoriness and rejection of solid organ transplants. Previously we demonstrated that pathogen reduction using UV light and riboflavin (UV + R) eliminates the immunogenicity of white blood cells (WBCs) in vitro, blocks alloim...

journal_title：Transfusion

authors： Muench MO,Heitman JW,Inglis H,Fomin ME,Marschner S,Goodrich RP,Norris PJ,Jackman RP

更新日期：2016-06-01 00:00:00

abstract：:The initial uptake of adenine from plasma by human red blood cells was measured at 0, 10, and 20 C. Initial uptake is completed in several minutes as distribution equilibrium is reached; however, total uptake requires several weeks at 4 C. Adenine inside the red blood cell was shown to egress to the plasma if the equi...

journal_title：Transfusion

authors： Moore GL,Ledford ME

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:The effects of transfusion of HLA antibodies to patients with corresponding antigens are not well known. STUDY DESIGN AND METHODS:Records of patients who received blood from previous donations of a donor implicated in a case of transfusion-related acute lung injury (TRALI) were examined. The donor had multi...

journal_title：Transfusion

authors： Toy P,Hollis-Perry KM,Jun J,Nakagawa M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:In this study whether metabolic suppression can be used to preserve platelet (PLT) function during prolonged storage was investigated. STUDY DESIGN AND METHODS:Washed human PLTs were incubated without glucose and with antimycin A to block energy generation. Metabolic suppressed PLTs (MSPs) were stored for 7...

journal_title：Transfusion

authors： Badlou BA,Ijseldijk MJ,Smid WM,Akkerman JW

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Reported hepatitis E virus (HEV) antibody assay performance characteristics are variable. Using a subset of surplus US blood donation samples, we compared assays for detecting anti-HEV immunoglobulin M (Ig)M and IgG or total anti-HEV antibodies. STUDY DESIGN AND METHODS:Samples from 5040 random blood donati...

journal_title：Transfusion

authors： Zafrullah M,Zhang X,Tran C,Nguyen M,Kamili S,Purdy MA,Stramer SL

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Though a number of studies have elegantly characterized platelet activation during storage, less attention has been paid to the initial activation caused by different collection procedures. STUDY DESIGN AND METHODS:The effects of two blood cell separators on the initial activation of platelets were measured...

journal_title：Transfusion

authors： Stohlawetz P,Hergovich N,Stiegler G,Eichler HG,Höcker P,Kapiotis S,Jilma B

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The 2016 Food and Drug Administration draft guidance describes the use of a rapid test (RT) to enhance platelet transfusion safety and availability. This study reports a 113-month experience of screening of apheresis platelets (APs) by RT. STUDY DESIGN AND METHODS:From July 2008 to October 2015, all APs und...

journal_title：Transfusion

authors： Ruby KN,Thomasson RR,Szczepiorkowski ZM,Dunbar NM

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The greatest limiting factor in the use of umbilical cord blood (UCB) for transplantations is the number of stem cells available in any given collected unit. This study examines maternal, neonatal, and obstetric factors that influence the suitability for banking and transplantation of UCB units collected in ...

journal_title：Transfusion

authors： Keersmaekers CL,Mason BA,Keersmaekers J,Ponzini M,Mlynarek RA

更新日期：2014-03-01 00:00:00

abstract：:Platelet concentrates were prepared by plateletpheresis using discontinuous flow centrifugation. Platelet units were stored in PL-146 bags of 300 ml and 2,000 ml capacity, and in vitro measures helpful in predicting platelet viability were compared. Storage in bags of 300 ml capacity led to significant fall in pH, dec...

journal_title：Transfusion

authors： Katz A,Houx J,Ewald L

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Information on the probability of survival of transfused patients is needed for policy making, but there is a paucity of empirical research into this question. A Swedish population-based study reported that the 40-month posttransfusion probability of survival was 51 percent in all patients and 41 percent in ...

journal_title：Transfusion

authors： Vamvakas EC,Goldstein R

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Concerns have been raised that aging of the general population will increase the demand for blood products. Modeling can be applied to assess trends in blood demand and supply and predict how these will develop over time. STUDY DESIGN AND METHODS:We developed mathematical models to describe and predict the ...

journal_title：Transfusion

authors： Borkent-Raven BA,Janssen MP,Van Der Poel CL

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Platelets (PLTs) stored in additive solutions (PASs) may reduce the risk of several plasma-associated adverse transfusion reactions such as allergic reactions and potentially transfusion-associated lung injury. The objective of this study was to determine the in vitro characteristics and the in vivo radiolab...

journal_title：Transfusion

authors： Dumont LJ,Cancelas JA,Graminske S,Friedman KD,Vassallo RR,Whitley PH,Rugg N,Dumont DF,Herschel L,Siegal AH,Szczepiorkowski ZM,Fender L,Razatos A

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Safe, accurate methods permitting simultaneous and/or repeated measurement of red blood cell (RBC) survival (RCS) are important to investigate pathophysiology and therapy of anemia. Methods using chromium 51 ((51) Cr)-labeled RBCs are unacceptable for infants, children, and pregnant women. We report RCS meas...

journal_title：Transfusion

authors： Mock DM,Matthews NI,Zhu S,Strauss RG,Schmidt RL,Nalbant D,Cress GA,Widness JA

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions. The purpose of this study was to prospectively compare the risk of transfusion reactions in hematology/oncology patients who receive acetaminophen with diphenhydramine or placebo before transfu...

journal_title：Transfusion

authors： Kennedy LD,Case LD,Hurd DD,Cruz JM,Pomper GJ

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Improving apheresis technology may lead to an efficient and safe peripheral blood stem cell (PBSC) collection. Recently, the Spectra Optia (Optia, Terumo BCT) was introduced as an automated apheresis instrument, but comparisons with other instruments have been few. This is the first randomized multicenter an...

journal_title：Transfusion

authors： Ikeda K,Minakawa K,Muroi K,Fujiwara SI,Yamada-Fujiwara M,Fujimori Y,Tanosaki R,Ohto H,Study Group for Peripheral Blood Stem Cell Collection, Cell Therapy Committee, The Japan Society of Transfusion Medicine and Cell Therapy.

更新日期：2016-11-01 00:00:00