Lung transplantation complicated by graft-versus-host disease and confounded by incidental transfusion-associated macrochimerism.

abstract：:Blood Centers of California, Inc. (BCC) is a consortium of 19 independent blood centers that collectively draw approximately 800,000 units of whole blood each year. Over the past several years, a committee of BCC, composed primarily of medical and nursing directors at member institutions, developed a Uniform Donor Med...

journal_title：Transfusion

authors： Kolins J,Silvergleid AJ

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Donor white cells (WBCs) in blood transfusions are responsible for complications in recipients, including alloimmunization, graft-versus-host disease (GVHD), and virus transmission and reactivation. The recent use of sequence-specific polymerase chain reaction assays to monitor the kinetics of clearance of d...

journal_title：Transfusion

authors： Goodarzi MO,Lee TH,Pallavicini MG,Donegan EA,Busch MP

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Overproduction of beta-chemokines and genetic variations in chemokine receptors have been correlated with protection against infection by HIV-1 or slow progression to AIDS in infected individuals. STUDY DESIGN AND METHODS:The protective role of chemokines and their receptors was evaluated in a group of seve...

journal_title：Transfusion

authors： Barretina J,Blanco J,Gutiérrez A,Puig L,Altisent C,Espanol T,Caragol I,Clotet B,Esté JA

更新日期：2000-04-01 00:00:00

abstract：:Lyophilized factor VIII concentrates, because of their convenience, are the most commonly used products for providing antihemophilic factor to patients with hemophilia A. Heightened concerns about associated complications indicate that cryoprecipitate usage will increase in the immediate future. We present a protocol ...

journal_title：Transfusion

authors： Menitove JE,Spero JA,Richards WA,Lewis JH,Montgomery RR,Gill JC,Hasiba U,Wheeler DV,Sherwin JA,Russell-Vaskov S,Marlar RA,Maxwell NG,Aster RH

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:The usefulness of DNA genotyping for RBC antigens as a tool for the management of multiply-transfused patients with sickle cell disease (SCD) to overcome the limitations of hemagglutination assays was evaluated. STUDY DESIGN AND METHODS:Blood samples from 40 multiply-transfused SCD patients were studied by ...

journal_title：Transfusion

authors： Castilho L,Rios M,Bianco C,Pellegrino J Jr,Alberto FL,Saad ST,Costa FF

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Patients with autoimmune lymphoproliferative syndrome (ALPS) have an autosomal dominant genetic defect that affects lymphocyte apoptosis and is associated with chronic nonmalignant lymphadenopathy, splenomegaly, and autoimmunity, particularly affecting RBCs, WBCs, and platelets. STUDY DESIGN AND METHODS:DAT...

journal_title：Transfusion

authors： Stroncek DF,Carter LB,Procter JL,Dale JK,Straus SE

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Blood donor parvovirus B19 DNA prevalence with sensitive nucleic acid test assays has recently been demonstrated to be higher than that found with assays designed to detect high viral titers in the plasma manufacturing sector. STUDY DESIGN AND METHODS:Stored plasma aliquots from 5020 donations collected bet...

journal_title：Transfusion

authors： Kleinman SH,Glynn SA,Lee TH,Tobler L,Montalvo L,Todd D,Kiss JE,Shyamala V,Busch MP,National Heart, Lung, Blood Institute Retrovirus Epidemiology Donor Study (REDS-II).

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The RBC injury that occurs during collection of the first few milliliters of blood into the pH 5.0 ACD (NIH, Formula A) is referred to as the lesion of collection. The RBC injury was evaluated by labeling the ACD RBCs with (51)Cr and measuring the 24-hour posttransfusion survival. The effect of the acidifica...

journal_title：Transfusion

authors： Valeri CR,Pivacek LE,Cassidy GP,Ragno G

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Determination of the white cell (WBC) count in WBC-reduced platelet components requires methods that have a detection limit in the range of approximately 5.0 x 10(2) to 5.0 x 10(4) per mL. STUDY DESIGN AND METHODS:With a 50-microL Nageotte hemocytometer and bright-field microscopy (200x magnification), stud...

journal_title：Transfusion

authors： Moroff G,Eich J,Dabay M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Obstetric services depend on the transfusion service (TS) to provide diagnostic testing and blood component therapy for clinical care pathways. STUDY DESIGN AND METHODS:We describe three quality improvement (QI) initiatives implemented to improve TS support of obstetric services. RESULTS:We implemented a p...

journal_title：Transfusion

authors： Goodnough LT,Daniels K,Wong AE,Viele M,Fontaine MF,Butwick AJ

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Dengue fever and hemorrhagic disease are caused by four dengue virus (DENV) serotypes (DENV-1 to -4), mosquito-borne flaviviruses with increasing incidence, and expanding global distributions. Documented transfusion transmission of West Nile virus raised concern regarding transfusion-transmitted DENV. METHO...

journal_title：Transfusion

authors： Linnen JM,Vinelli E,Sabino EC,Tobler LH,Hyland C,Lee TH,Kolk DP,Broulik AS,Collins CS,Lanciotti RS,Busch MP

更新日期：2008-07-01 00:00:00

abstract：:Cell pheresis was employed in the initial management of a pregnant patient with chronic myelocytic leukemia (CML). Reduction in circulating leukocyte and platelet counts was evident after two weeks of therapy. This technique is an effective mode of management of the pregnant patient with CML and may play an important ...

journal_title：Transfusion

authors： Caplan SN,Coco FV,Berkman EM

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:National guidance recommends planning for future blood shortages, but few studies have evaluated how reduced demand could be achieved acutely. STUDY DESIGN AND METHODS:A trained observer collected data concerning red blood cell (RBC) transfusion events outside the operating theater during 68 hours of blood ...

journal_title：Transfusion

authors： Joseph BG,Hendry C,Walsh TS

更新日期：2009-10-01 00:00:00

abstract：:The hemostat, sealant, and adhesive components of the surgical toolbox continue to evolve and enter clinical practice at a rapid rate. The goal of this comprehensive, sequential review is to update these components to include those now available (February 2012) as well as to explore cost and regulatory factors that im...

journal_title：Transfusion

authors： Spotnitz WD,Burks S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:A case of donor cell leukemia (DCL) is reported. A 42-year-old female developed acute myeloid leukemia (AML) of donor cell origin 18 months after a bone marrow transplant (BMT) from her brother. At the time DCL presented, the donor-brother was also diagnosed with AML showing identical cytogenetic abnormaliti...

journal_title：Transfusion

authors： Glasser L,Meloni-Ehrig A,Greaves W,Demel KC,Butera J

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Hemolytic disease of the fetus and newborn (HDFN) is a severe disease, resulting from maternal red cell (RBC) alloantibodies directed against fetal RBCs. The effect of a first-trimester antibody screening program on the timely detection of HDFN caused by antibodies other than anti-D was evaluated. STUDY DES...

journal_title：Transfusion

authors： Koelewijn JM,Vrijkotte TG,van der Schoot CE,Bonsel GJ,de Haas M

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:In August 2016, the Food and Drug Administration advised US blood centers to screen all whole blood and apheresis donations for Zika virus (ZIKV) with an individual-donor nucleic acid test (ID-NAT) or to use approved pathogen reduction technology (PRT). The cost of implementing this guidance nationally has n...

journal_title：Transfusion

authors： Ellingson KD,Sapiano MRP,Haass KA,Savinkina AA,Baker ML,Henry RA,Berger JJ,Kuehnert MJ,Basavaraju SV

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Successful hematopoietic stem cell transplantation using stored umbilical cord blood (CB) largely depends on cell dose and quality of CB units. The aim of this study was to assess the degree of early apoptosis, in addition to cell viability and hematopoietic potential, in umbilical CB units after storage. S...

journal_title：Transfusion

authors： Kim KM,Huh JY,Hong SS,Kang MS

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:CD34 flow cytometry is the gold standard for stem cell enumeration in peripheral blood at the mobilization stage and in the final apheresis product. The new stem cell mode of the Sysmex XN Series analyzer enumerates an immature cell population in the white progenitor and pathological cell (WPC) channel, base...

journal_title：Transfusion

authors： Grommé M,Russcher H,Braakman E,Klinkspoor JH,Dobber JA,de Greef I,de Wit NCJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Hypoxia is a major cause of painful vaso-occlusive crisis in sickle cell disease (SCD). Simple transfusion and red blood cell (RBC) exchange are commonly used as preventive therapies whose aim is to dilute hemoglobin (Hb)S-containing RBCs (SS-RBCs) with normal RBCs (AA-RBCs) to prevent sickling. We hypothesi...

journal_title：Transfusion

authors： Bourgeaux V,Hequet O,Campion Y,Delcambre G,Chevrier AM,Rigal D,Godfrin Y

更新日期：2010-10-01 00:00:00

abstract：:ALX148, a novel CD47 blocking agent, is in clinical development for the treatment of advanced solid tumors and lymphoma. Because CD47 is highly expressed on red blood cells (RBCs), its therapeutic blockade can potentially interfere with pretransfusion compatibility testing. This study describes the interference of ALX...

journal_title：Transfusion

authors： Kim TY,Yoon MS,Hustinx H,Sim J,Wan HI,Kim H

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) storage lesions and RBCs from females transfused into male recipients may have adverse effects on transfusion recipients' survival. We hypothesized that the effect of donor sex and the effect of age of blood on mortality would be most apparent in cardiac surgery patients. STUDY DESIGN A...

journal_title：Transfusion

authors： Desmarets M,Bardiaux L,Benzenine E,Dussaucy A,Binda D,Tiberghien P,Quantin C,Monnet E

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:A sample mix-up occurred in a tissue procurement laboratory in which aliquots of serum from two tissue donors were accidentally mislabeled. The clues to the apparent mixup involved discrepant Hepatitis C test results. In an attempt to resolve the apparent mix up, DNA typing was performed using serum samples ...

journal_title：Transfusion

authors： Allen RW,Pritchard JK

更新日期：2004-12-01 00:00:00

abstract：:Red cells (RBCs) prepared by a new system using centrifugation to produce neocyte enrichment were studied in two laboratories. The system used a blood bag with a geometric configuration such that younger, less dense cells could be separated from older, denser cells. Phthalate ester density gradient curves determined t...

journal_title：Transfusion

authors： Simon TL,Sohmer P,Nelson EJ

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Although the need for whole blood is declining, so too are the number of first-time and repeat blood donors. To develop new recruitment and retention strategies, therefore, we need to draw on as wide a variation in blood donor motivations as possible. The primary aim of this study is to draw on a large surve...

journal_title：Transfusion

authors： Ferguson E,Hill A,Lam M,Reynolds C,Davison K,Lawrence C,Brailsford SR

更新日期：2020-09-01 00:00:00

abstract：:The ability to store platelets beyond 24 hours requires a functionally closed system. This study tested the ability of a cell separator bowl seal system to resist penetration of microbial contamination under normal running conditions and under extreme environmental stress. Three test organisms, Micrococcus luteus, Ser...

journal_title：Transfusion

authors： Jacobson MS,Kevy SV,Thorne GM,Goldmann DA,Blasetti L,Smith JW,Schaefer H

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the potential yield of introducing nucleic acid amplification testing (NAT) in blood donation, according to the detection threshold and the pool size. STUDY DESIGN AND METHODS:A mathematical model of early HIV-1 population dynamics in blood has been developed and is used ...

journal_title：Transfusion

authors： Le Corfec E,Le Pont F,Tuckwell HC,Rouzioux C,Costagliola D

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Mathematical models predict that, in Spain, a significant number of blood units will be obtained during the window period of the hepatitis B virus (HBV) infection. Routine nucleic acid testing (NAT) on individual blood units may provide experimental data to evaluate such a theoretical risk. STUDY DESIGN AND...

journal_title：Transfusion

authors： González R,Echevarria JM,Avellón A,Barea L,Castro E

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Variant RHCE alleles with diminished expression of C, c, E, and e antigens have been described and indicate the genetic diversity of this gene locus in several populations. In this study the molecular background of variant RhCE antigens identified by standard serologic routine testing in German blood donors ...

journal_title：Transfusion

authors： Bugert P,Scharberg EA,Geisen C,von Zabern I,Flegel WA

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Platelets for transfusion become senescent and dysfunctional during storage, resulting in a markedly short shelf life (5 days). We hypothesized that oxidative stress might account for this decline. STUDY DESIGN AND METHODS:Human platelets were treated with or without antioxidants before storage, and samples...

journal_title：Transfusion

authors： Wang L,Xie R,Fan Z,Yang J,Liang W,Wu Q,Wu MX,Wang Z,Lu Y

更新日期：2019-07-01 00:00:00