Comparison of the recovery and half-life of a high-purity factor IX concentrate with those of a factor IX complex concentrate. Factor IX Study Group.

abstract：BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...

journal_title：Transfusion

authors： Bruhn R,Moreno E,Sabino EC,Ferreira NA,Carneiro-Proietti AB,Lopes ME,Sampaio D,Loureiro P,Custer B,Goncalez TT,National Heart, Lung and Blood Institute Retrovirus Epidemiology Donor Study-II (REDS-II) International Component.

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:WBC reduction of cellular blood components has been introduced in many countries. Owing to concerns of residual WBCs in plasma, a new method to collect WBC-reduced plasma by apheresis was studied. STUDY DESIGN AND METHODS:An apheresis machine (PCS2, Haemonetics) was used, in combination with the "high-separ...

journal_title：Transfusion

authors： Vrielink H,van der Meer PF

更新日期：2004-06-01 00:00:00

abstract：:A method is described which absorbs anti-Chido from serum without reducing the strength of other alloantibodies. Autologous red blood cells are coated with homologous C4 by a low-ionic-strength method and then used for the absorption. This is a practical method for removing anti-Chido from serum so that underlying all...

journal_title：Transfusion

authors： Ellisor SS,Shoemaker MM,Reid ME

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:At Canadian Blood Services, platelet concentrate (PC) shelf life was extended to 7 days with a large-volume, delayed-sampling bacterial screening algorithm. We present the development study and postimplementation results. STUDY DESIGN AND METHODS:In the development study, PCs inoculated with five bacteria (...

journal_title：Transfusion

authors： Ramirez-Arcos S,Evans S,McIntyre T,Pang C,Yi QL,DiFranco C,Goldman M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Platelet transfusion-associated sepsis is usually due to donor skin flora introduced into the unit during phlebotomy. An unusual case of a platelet component contaminated with methicillin-resistant Staphylococcus aureus (MRSA) is reported. CASE REPORT:A 54-year-old man, terminally ill with progressive non-H...

journal_title：Transfusion

authors： Sapatnekar S,Wood EM,Miller JP,Jacobs MR,Arduino MJ,McAllister SK,Kellum ME,Roth V,Yomtovian R

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Transfusion of the incorrect blood component is a frequent serious incident associated with transfusion and often involves misidentification of the patient and/or the unit of blood. The objective of this study was to assess the effect of a simple intervention designed to improve performance of the bedside ch...

journal_title：Transfusion

authors： Murphy MF,Casbard AC,Ballard S,Shulman IA,Heddle N,Aubuchon JP,Wendel S,Thomson A,Hervig T,Downes K,Carey PM,Dzik WH,BEST Research Collaborative.

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Effective risk communication in transfusion medicine is important for health-care consumers, but understanding the numerical magnitude of risks can be difficult. The objective of this study was to determine the effect of a visual risk communication tool on the knowledge and perception of transfusion risk. S...

journal_title：Transfusion

authors： Lee DH,Mehta MD

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:A quality monitoring program (QMP) for platelet concentrates (PCs) was implemented at Canadian Blood Services (CBS) to improve standards and to better understand platelet (PLT) products by supplementing routine quality control (QC). STUDY DESIGN AND METHODS:Annual surveys of PCs from CBS production sites we...

journal_title：Transfusion

authors： Levin E,Jenkins C,Culibrk B,Gyöngyössy-Issa MI,Serrano K,Devine DV

更新日期：2012-04-01 00:00:00

abstract：:Dextran 40 is the main component of the solution used to wash or dilute thawed cord blood unit (CBU) products for stem cell transplant. Dextran 40 became unavailable in the United States as of April 2014. Like many other cellular therapy laboratories in the United States, we found ourselves with limited dextran 40 inv...

journal_title：Transfusion

authors： Reich-Slotky R,Bachegowda LS,Ancharski M,Mendeleyeva L,Rubinstein P,Rennert H,Shore T,van Besien K,Cushing M

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The intrinsic properties of polypeptide blood group antigens that determine their relative immunogenicities are unknown. Because size, composition, charge, dose, and epitope glycosylation affect the immunogenicity of other polypeptides, we examined whether similar properties were related to the immunogenicit...

journal_title：Transfusion

authors： Howe JG,Stack G

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:Frozen plasma is superior to crystalloids for hemorrhage resuscitation but remains logistically challenging in austere environments because of specialized clinical equipment for on-demand thawing. This research examines some ad hoc thawing techniques that have been implemented by military medical personnel...

journal_title：Transfusion

authors： Meledeo MA,Peltier GC,McIntosh CS,Corley JB,Bynum JA,Cap AP

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Our blood bank is part of a large academic institution with an active sickle cell anemia program. We provide sickle patients with blood phenotypically matched for C/c, E/e, and K antigens. Since licensed reagents are available for phenotyping C/c, E/e, and K on an automated blood analyzer, we decided to eval...

journal_title：Transfusion

authors： Le N,Harach ME,Kay JK,Brown RP,Everetts JN,Herman JH

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Serious complications of blood donation are rare. Reported here is a significant vascular event that resulted from whole-blood phlebotomy and required surgical repair. CASE REPORT:A 49-year-old woman donated whole blood without incident in November 1992, but reported ecchymosis and tenderness in the antecub...

journal_title：Transfusion

authors： Popovsky MA,McCarthy S,Hawkins RE

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Stored red blood cells (RBCs) undergo progressive deleterious functional, biochemical, and structural changes. The mechanisms responsible for the adverse effects of transfusing stored RBCs remain incompletely elucidated. STUDY DESIGN AND METHODS:Awake wild-type (WT) mice, WT mice fed a high-fat diet (HFD-fe...

journal_title：Transfusion

authors： Yu B,Lei C,Baron DM,Steinbicker AU,Bloch KD,Zapol WM

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) is one of the most serious adverse events following transfusion, and there is no specific treatment in clinical practice. However, regulatory T cells (Tregs) have been suggested to play a potential role in the treatment of TRALI. This study investigated whether i...

journal_title：Transfusion

authors： He R,Li L,Kong Y,Tian L,Tian X,Fang P,Bian M,Liu Z

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The decision to transfuse red blood cells in surgical patients should be based on multiple clinical variables, rather than on isolated hemoglobin (Hb) measurements alone. An important but often unrecognized clinical variable is the postoperative downward drift in Hb concentration (Hb drift), but the etiology...

journal_title：Transfusion

authors： Grant MC,Whitman GJ,Savage WJ,Ness PM,Frank SM

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The usefulness of DNA genotyping for RBC antigens as a tool for the management of multiply-transfused patients with sickle cell disease (SCD) to overcome the limitations of hemagglutination assays was evaluated. STUDY DESIGN AND METHODS:Blood samples from 40 multiply-transfused SCD patients were studied by ...

journal_title：Transfusion

authors： Castilho L,Rios M,Bianco C,Pellegrino J Jr,Alberto FL,Saad ST,Costa FF

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Platelets for transfusion become senescent and dysfunctional during storage, resulting in a markedly short shelf life (5 days). We hypothesized that oxidative stress might account for this decline. STUDY DESIGN AND METHODS:Human platelets were treated with or without antioxidants before storage, and samples...

journal_title：Transfusion

authors： Wang L,Xie R,Fan Z,Yang J,Liang W,Wu Q,Wu MX,Wang Z,Lu Y

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Delayed hemolysis mediated by long-term production of pre-existing recipient-derived antibodies directed against donor RBC antigens after allogenic BMT is an unusual complication of hematopoietic transplantation. CASE REPORT:A 26-year-old man with aplastic anemia had pre-existing alloantibodies to E and c. ...

journal_title：Transfusion

authors： Izumi N,Fuse I,Furukawa T,Uesugi Y,Tsuchiyama J,Toba K,Togashi K,Yamada K,Ohtake S,Saitoh Y,Yanagisawa N,Aizawa Y

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:A simple and rapid slide Polybrene method (SP) for pretransfusion compatibility testing is described. SP is particularly suitable for use in developing countries where, due to limited resources, centrifuges and biologic reagents may not be readily available. STUDY DESIGN AND METHODS:The original manual Poly...

journal_title：Transfusion

authors： Lin M

更新日期：2004-03-01 00:00:00

abstract：:Blood centrifugation, with a continuous-flow or semicontinuous-flow system, was used in the treatment of 17 patients with various hematologic disorders. Total plasma exchange (TPE) controlled symptoms of hyperviscosity and arrested bleeding in three patients. In two patients, TPE made is possible to perform urgent sur...

journal_title：Transfusion

authors： Pineda AA,Brzica SM Jr,Taswell HF

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Deferasirox (DFRA) is a new approved oral iron chelator. Its advantages are that it is convenient and better tolerated and adhered to due to "once-daily" oral dosage. However, its use in the field is limited and it is yet to be subjected to postmarketing surveillance. CASE REPORT:A 18.75-year-old male with ...

journal_title：Transfusion

authors： Wei HY,Yang CP,Cheng CH,Lo FS

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The safety of fibrin tissue adhesives has been a concern since they entered wide clinical application. Most commercially available kits contain the proteolytic inhibitor, aprotinin, to stabilize the fibrin clot. A bovine protein, this substance has an allergenic potency. CASE REPORT:This case report present...

journal_title：Transfusion

authors： Beierlein W,Scheule AM,Antoniadis G,Braun C,Schosser R

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Most patients with severe aplastic anemia (sAA) respond to immunosuppression, but a significant number relapse or develop clonal abnormalities such as paroxysmal nocturnal hemoglobinuria, myelodysplasia, or leukemia. In principle, patients without matched sibling donors and older patients might benefit from ...

journal_title：Transfusion

authors： Sloand EM,Read EJ,Scheinberg P,Tang Y,More K,Leitman SF,Maciejewski J,Young NS

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) is the most common cause of death from blood transfusion and red blood cells (RBCs) now account for approximately 50% of these fatalities. RBCs from female donors have been implicated in large series and HLA Class II antibodies to cognate recipient antigens ident...

journal_title：Transfusion

authors： Weber LL,Roberts LD,Sweeney JD

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Platelet factor 4 (PF4) is a marker for in vitro and in vivo tests of platelet (PLT) activation and alpha-granule secretion. PF4 is also a major CXC cytokine released during storage. Cytokines released during PLT storage are a potential cause of nonhemolytic transfusion reactions. Quantitative measurement of...

journal_title：Transfusion

authors： Schraw T,Whiteheart S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Because the frequency of umbilical cord blood (UCB) stem cell transplantation has increased, the quality of UCB available in banks is an important part of the success of UCB stem cell transplants. STUDY DESIGN AND METHODS:A quality assurance monitoring system was used to evaluate 268 UCB units provided to u...

journal_title：Transfusion

authors： McCullough J,McKenna D,Kadidlo D,Schierman T,Wagner J

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The survival of fresh and preserved platelets has been used primarily to determine their therapeutic effectiveness. The function of the fresh and preserved platelets has been difficult to assess. In stable thrombocytopenic patients, platelet function of fresh and preserved allogeneic platelets is evaluated b...

journal_title：Transfusion

authors： Valeri CR,MacGregor H,Giorgio A,Ragno G

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Evaluation of hemostasis in bleeding patients requires both accuracy and speed. STUDY DESIGN AND METHODS:As an alternative to point-of-care testing, we developed an emergency hemorrhage panel (EHP: prothrombin time [PT], fibrinogen, platelet count, hematocrit) for use in making transfusion decisions on blee...

journal_title：Transfusion

authors： Chandler WL,Ferrell C,Trimble S,Moody S

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Photochemical pathogen inactivation treatment (PCT) of plasma components with amotosalen and UVA has been implemented in Europe. To establish a postapproval safety database, an active hemovigilance (HV) program utilizing an electronic data capture system (EDCS) was initiated. STUDY DESIGN AND METHODS:The re...

journal_title：Transfusion

authors： Cazenave JP,Waller C,Kientz D,Mendel I,Lin L,Jacquet M,Propst M,Liu W,Corash L,Sundin D,Defoin L,Messe N,Osselaer JC

更新日期：2010-06-01 00:00:00