Issues in the quality of umbilical cord blood stem cells for transplantation.

abstract：:The potassium load of transfused blood must be minimized. We have compared the total plasma potassium content of units of CPD-preserved stored whole blood (SWB), stored packed cells (SPC), and packed cells prepared from stored whole blood (WB-PC). Plasma potassium concentrations, unit weights, and hematocrits of 20 un...

journal_title：Transfusion

authors： Michael JM,Dorner I,Bruns D,Ladenson JH,Sherman LA

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:When bacteria are found, after a platelet transfusion, in the recipient's blood as well as in the platelet concentrate (PC), a causal relationship is normally suspected, with the PC as the causative agent. The other alternative, that the patient has bacteremia and contaminated the PC, is less well documented...

journal_title：Transfusion

authors： Engstrand M,Engstrand L,Högman CF,Hambraeus A,Branth S

更新日期：1995-10-01 00:00:00

abstract：:Analysis of blood coagulation was done on samples of blood collected from ten donors undergoing combined platelet and leukapheresis using the Haemonetics Model 30 Blood Processor. Blood samples were obtained from the donors prior to, during, and following pheresis. Blood was also obtained from the blood-return line af...

journal_title：Transfusion

authors： Kisker CT,Strauss RG,Koepke JA,Maguire LC,Thompson JS

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:DNA testing has enabled the documenting of numerous variants of RHCE alleles, especially in individuals of African origin. The risk for production of clinically significant alloantibodies to Rh antigens of patients carrying variant RHCE alleles has led us to analyze the different RhCE variants investigated b...

journal_title：Transfusion

authors： Pham BN,Peyrard T,Juszczak G,Beolet M,Deram G,Martin-Blanc S,Dubeaux I,Roussel M,Kappler-Gratias S,Gien D,Poupel S,Rouger P,Le Pennec PY

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Improving apheresis technology may lead to an efficient and safe peripheral blood stem cell (PBSC) collection. Recently, the Spectra Optia (Optia, Terumo BCT) was introduced as an automated apheresis instrument, but comparisons with other instruments have been few. This is the first randomized multicenter an...

journal_title：Transfusion

authors： Ikeda K,Minakawa K,Muroi K,Fujiwara SI,Yamada-Fujiwara M,Fujimori Y,Tanosaki R,Ohto H,Study Group for Peripheral Blood Stem Cell Collection, Cell Therapy Committee, The Japan Society of Transfusion Medicine and Cell Therapy.

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Hypothermic storage transforms red blood cells (RBC) from smooth biconcave discocytes into increasingly spherical spiculated echinocytes and, ultimately, fragile spherocytes (S). Individual cells undergo this transformation at different rates, producing a heterogeneous mixture of RBCs at all stages of echino...

journal_title：Transfusion

authors： Lu M,Shevkoplyas SS

更新日期：2020-08-04 00:00:00

abstract：:Soft and hard-packed red blood cells in four different CPD anticoagulant-preservative solutions were stored with and without added glucose, adenine, and electrolytes. The hemoglobin-oxygen affinity of the red blood cell concentrates was tested over a six-week storage period. No single solution conferred better protect...

journal_title：Transfusion

authors： Wells RM,Hill RS,Woodfield DG

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:The greatest limiting factor in the use of umbilical cord blood (UCB) for transplantations is the number of stem cells available in any given collected unit. This study examines maternal, neonatal, and obstetric factors that influence the suitability for banking and transplantation of UCB units collected in ...

journal_title：Transfusion

authors： Keersmaekers CL,Mason BA,Keersmaekers J,Ponzini M,Mlynarek RA

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The AABB Clinical Transfusion Medicine Committee (CTMC) compiles an annual synopsis of the published literature covering important developments in the field of transfusion medicine (TM) for the board of director's review. This synopsis is now made available as a manuscript published in TRANSFUSION. STUDY DE...

journal_title：Transfusion

authors： Pagano MB,Allen ES,Chou ST,Dunbar NM,Gniadek T,Goel R,Harm SK,Hopkins CK,Jacobson J,Lokhandwala PM,Metcalf RA,Raval JS,Schwartz J,Shan H,Spinella PC,Storch E,Cohn CS

更新日期：2020-07-01 00:00:00

abstract：:Quality control to detect inadequately deglycerolized red blood cells can be easily and inexpensively accomplished by suspending the deglycerolized cells in either recipient serum or normal saline in the same way in which the routine crossmatch is performed. In vitro hemolysis is readily and consistently apparent when...

journal_title：Transfusion

authors： Silver H,Umlas J,Kenney P,Anderson J,Pina B,Cross D

更新日期：1982-05-01 00:00:00

abstract：:A prospective study of newborn infants who required exchange transfusion was undertaken to evaluate the risk of transmission of cytomegalovirus (CMV). Buffy coat-, urine- and saliva-saturated throat swabs for viral cultures and serum specimens for CMV complement-fixing (CF) antibody were obtained from 45 infant-mother...

journal_title：Transfusion

authors： Kumar A,Nankervis GA,Cooper AR,Gold E,Kumar ML

更新日期：1980-05-01 00:00:00

abstract：:Transfusion practices have changed dramatically in recent years as a result of the acquired immune deficiency syndrome crisis. The use of preoperative donation of autologous blood units has gained popularity. Healthy individuals tolerate phlebotomy well, experiencing a 2- to 5-percent incidence of vasovagal reactions....

journal_title：Transfusion

authors： Spiess BD,Sassetti R,McCarthy RJ,Narbone RF,Tuman KJ,Ivankovich AD

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Detection of viral nucleic acids might increase blood transfusion safety through the detection of recently infected blood donors during the preseroconversion window period. Individual screening is difficult to apply, because of technical and financial constraints. STUDY DESIGN AND METHODS:A polymerase chain...

journal_title：Transfusion

authors： Yerly S,Pedrocchi M,Perrin L

更新日期：1998-10-01 00:00:00

abstract：:The vasodilative effects associated with the use of sodium acetate have been reported in the literature. Preparations of plasma protein fraction (PPF) substantially free of this vasodilator were developed. This paper presents and discusses experimental work on the improved product. ...

journal_title：Transfusion

authors： Ng PK,Fournel MA,Lundblad JL

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:A pilot study was conducted to determine the safety and feasibility of intravenous administration of autologous umbilical cord blood (CB) in young children with acquired neurologic disorders. Most CB units (CBUs) were electively stored in private CB banks. Unlike public banks, which utilize specific criteria...

journal_title：Transfusion

authors： Sun J,Allison J,McLaughlin C,Sledge L,Waters-Pick B,Wease S,Kurtzberg J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Mathematical models predict that, in Spain, a significant number of blood units will be obtained during the window period of the hepatitis B virus (HBV) infection. Routine nucleic acid testing (NAT) on individual blood units may provide experimental data to evaluate such a theoretical risk. STUDY DESIGN AND...

journal_title：Transfusion

authors： González R,Echevarria JM,Avellón A,Barea L,Castro E

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Blood centers and hospital transfusion services are challenged with maintaining an adequate platelet (PLT) inventory to minimize the number of outdated units without risking a major shortage. A novel approach to inventory management was established at our institution through a collaboration between the Stanf...

journal_title：Transfusion

authors： Fontaine MJ,Chung YT,Rogers WM,Sussmann HD,Quach P,Galel SA,Goodnough LT,Erhun F

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:In experimental pneumonia we found that transfused older blood increased mortality and lung injury that was associated with increased in vivo hemolysis and elevated plasma cell-free hemoglobin (CFH), non-transferrin-bound iron (NTBI), and plasma labile iron (PLI) levels. In this study, we additionally analyz...

journal_title：Transfusion

authors： Wang D,Cortés-Puch I,Sun J,Solomon SB,Kanias T,Remy KE,Feng J,Alimchandani M,Quezado M,Helms C,Perlegas A,Gladwin MT,Kim-Shapiro DB,Klein HG,Natanson C

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Donor WBCs are responsible for numerous transfusion complications, but little is known concerning the natural history of their clearance following transfusion or of their function in the recipient's circulation. A murine transfusion model was developed to investigate the effects of blood component characteri...

journal_title：Transfusion

authors： Lee TH,Reed W,Mangawang-Montalvo L,Watson J,Busch MP

更新日期：2001-05-01 00:00:00

abstract：:Newly prepared platelet concentrates (PC) and platelet poor plasma (PPP) stored at either room temperature (RT) or 4 C were analyzed for ammonia content initially, and after storage at 24, 48, and 72 hours. These studies demonstrate that ammonia rapidly accumulates in PC stored at RT. This accumulation appears to be t...

journal_title：Transfusion

authors： Ukrainski CT,Goldfinger D,Pomerance JJ,Lee HC,Farber S,Sanchez R

更新日期：1981-01-01 00:00:00

abstract：:Our computer system currently stores donor blood types for seven years and checks typing of all repeat donors against these files. In a recent three-month period (42,500 units), five discrepancies were found--two representing current error. Retrospective analysis of 18 errors made over the last three years showed that...

journal_title：Transfusion

authors： Grindon AJ,Liles BA

更新日期：1981-03-01 00:00:00

abstract：:Several blood transfusion filters designed to remove microemboli were evaluated for filtration and flow characteristics, as well as for hemolysis and for release of particulate debris from the filter. The Dacron wool filter, a depth filter, was superior at removing microemboli measured with an electronic particle size...

journal_title：Transfusion

authors： Kennedy PS,Solis RT,Scott MA,Wilson RK

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Storage age of red blood cells (RBCs) has been reported to be associated with increased mortality and morbidity. During storage, RBCs undergo changes in biochemical and functional properties. Stored RBCs may also contain white blood cells (WBCs), activated platelets (PLTs), cytokines, immunoglobulin, and oth...

journal_title：Transfusion

authors： Sowemimo-Coker SO

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Surgical patients receive platelet concentrates (PCs) for a variety of indications. However, there is limited evidence for efficacy or dosing of PCs. STUDY DESIGN AND METHODS:We performed a retrospective cohort study of surgical patients receiving isolated PC transfusion at a single academic tertiary medica...

journal_title：Transfusion

authors： Anders M,Rock P,Cartron A,Chow J,Henderson R,Martz D,Tanaka K,Mazzeffi M

更新日期：2019-05-01 00:00:00

abstract：:Blood centrifugation, with a continuous-flow or semicontinuous-flow system, was used in the treatment of 17 patients with various hematologic disorders. Total plasma exchange (TPE) controlled symptoms of hyperviscosity and arrested bleeding in three patients. In two patients, TPE made is possible to perform urgent sur...

journal_title：Transfusion

authors： Pineda AA,Brzica SM Jr,Taswell HF

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Whole blood donors may experience post-donation symptoms such as fatigue, dizziness, or headache after blood donation, which could influence donor retention. We aimed to examine post-donation symptoms during 1 week after whole blood donation, investigate donor characteristics associated with symptoms, and ev...

journal_title：Transfusion

authors： Sweegers MG,Twisk JWR,Quee FA,Ferguson E,van den Hurk K

更新日期：2021-01-23 00:00:00

abstract：:A study was made of the metabolism by the rabbit of adenine administered intravenously at a dose of 35 mg/kg with 100 micronCi of 8-14C-adenine. The infused adenine was removed from the blood in two phases, first by diffusion into the tissues and second by metabolic reactions throughout the body. The adenine equilibra...

journal_title：Transfusion

authors： Bartlett GR

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV) viruses are of concern due to the potential of transfusion transmission in blood, especially in regions such as Southeast Asia where the viruses are endemic. The recent availability of nucleic acid testing (NAT) to screen blood donations on an automated pla...

journal_title：Transfusion

authors： Stanley J,Chongkolwatana V,Duong PT,Kitpoka P,Stramer SL,Dung NTT,Grimm KE,Pojanasingchod A,Suksomboonvong P,Galel SA

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:The 1000 Genomes Project provides a database of genomic variants from whole genome sequencing of 2504 individuals across five continental superpopulations. This database can enrich our background knowledge of worldwide blood group variant geographic distribution and identify novel variants of potential clini...

journal_title：Transfusion

authors： Montemayor-Garcia C,Karagianni P,Stiles DA,Reese EM,Smellie DA,Loy DA,Levy KY,Nwokocha M,Bueno MU,Miller JL,Klein HG

更新日期：2018-11-01 00:00:00