Can family or replacement blood donors become regular volunteer donors?

Abstract:

BACKGROUND:In sub-Saharan Africa (SSA) confirmed viral marker prevalence between family donors (FDs) and first-time volunteer nonremunerated donors (VNRDs) is similar. In a blood service collecting 10 units/1000 inhabitants, a questionnaire examined FD donation conditions and willingness of becoming repeat VNRDs. STUDY DESIGN AND METHODS:Four areas were explored: circumstances of visit to hospital, external pressure, experience of donating, and potential repeat donation. After donation and consent, research assistants administered 25 questions and, according to literacy, helped with translation and completion. RESULTS:Of 513 FDs, three-fourths were males (median age, 27 years). Only 1.3% were unemployed and more than 50% were students or teachers. Ties with hospitalized patient were family (76%), friends (13%), colleagues, or sharing place of worship (10%). Donating blood was the reason for visiting in 16.8% and 20.9% had previously donated blood probably as FDs. In one-third of FDs, the family asked for donation of which 10% was pressured by the unjustified reason that not donating was endangering the patient's life. For two-thirds of FDs, donation was given "because individuals were asked." Donation was a positive experience for 77% of donors, 62% being interested in predonation testing. Repeating donation was acceptable for 99% of 79% FDs answering. DISCUSSION:FDs are active in the population, are willing to donate blood if asked, are submitted to little pressure, do not receive incentives, and accept repeat donation. Except for circumstances of donation, FDs are not different from VNRDs and more directly motivated. They constitute a legitimate and important source to improve the blood supply in SSA.

journal_name

Transfusion

journal_title

Transfusion

authors

Asenso-Mensah K,Achina G,Appiah R,Owusu-Ofori S,Allain JP

doi

10.1111/trf.12216

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

797-804

issue

3 Pt 2

eissn

0041-1132

issn

1537-2995

journal_volume

54

pub_type

杂志文章
  • Barriers to blood donation in African communities in Australia: the role of home and host country culture and experience.

    abstract:BACKGROUND:An influx of African migrants and refugees can strain a host country's blood services, because often migrants have unique blood needs that cannot be sourced from local donors. To increase blood donation by the new migrants, host country blood services need to understand how blood and blood donations are view...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.03053.x

    authors: Polonsky MJ,Renzaho AM,Brijnath B

    更新日期:2011-08-01 00:00:00

  • A general method for concentrating blood samples in preparation for counting very low numbers of white cells.

    abstract:BACKGROUND:To count extremely low levels of white cells (WBCs) in WBC-reduced blood components, a larger volume of sample must be processed. The goal was to develop an all-purpose method for concentrating the samples obtained from WBC-reduced red cells or platelets. The method was designed to be compatible with a varie...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1997.37397240209.x

    authors: Szuflad P,Dzik WH

    更新日期:1997-03-01 00:00:00

  • Granulocyte-colony-stimulatory factor: a strong inhibitor of natural killer cell function.

    abstract:BACKGROUND:The human cytokine granulocyte-colony stimulatory factor (G-CSF) has found widespread application in the medical treatment of neutropenia and to mobilize hematopoietic stem cells used for transplantation. So far, the effect of G-CSF on natural killer (NK) cells has not been fully investigated. STUDY DESIGN ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02820.x

    authors: Schlahsa L,Jaimes Y,Blasczyk R,Figueiredo C

    更新日期:2011-02-01 00:00:00

  • Hematopoietic cell infusion-related adverse events in pediatric/small recipients in a prospective/multicenter study.

    abstract:BACKGROUND:Hematopoietic cell infusion-related adverse events (HCI-AEs) in hematopoietic stem cell transplantations (HSCTs) have been largely attributed to toxicity of dimethyl sulfoxide (DMSO) for cryopreservation, but HSC products also contain various cells and plasma components. Our recent prospective study of 1125 ...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/trf.15786

    authors: Ikeda K,Ohto H,Yamada-Fujiwara M,Okuyama Y,Fujiwara SI,Muroi K,Mori T,Kasama K,Kanamori H,Iseki T,Nagamura-Inoue T,Kameda K,Kanda J,Nagai K,Fujii N,Ashida T,Hirose A,Takahashi T,Minakawa K,Tanosaki R

    更新日期:2020-05-01 00:00:00

  • Comprehensive proteomic analysis of protein changes during platelet storage requires complementary proteomic approaches.

    abstract:BACKGROUND:Proteomics methods may be used to analyze changes occurring in stored blood products. These data sets can identify processes leading to storage-associated losses of blood component quality such as the platelet (PLT) storage lesion (PSL). The optimal strategy to perform such analyses to obtain the most inform...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01546.x

    authors: Thon JN,Schubert P,Duguay M,Serrano K,Lin S,Kast J,Devine DV

    更新日期:2008-03-01 00:00:00

  • Erythrocytapheresis for chronic transfusion therapy in sickle cell disease: survey of current practices and review of the literature.

    abstract:BACKGROUND:Chronic red blood cell (RBC) transfusion therapy (CTT) is an integral component of the management of severe sickle cell disease (SCD) and can prevent complications, such as stroke. RBC units can be administered via simple transfusion or exchange transfusion, and erythrocytapheresis (automated RBC exchange tr...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.13800

    authors: Kelly S,Quirolo K,Marsh A,Neumayr L,Garcia A,Custer B

    更新日期:2016-11-01 00:00:00

  • Efficacy of single-dose pegfilgrastim after chemotherapy for the mobilization of autologous peripheral blood stem cells in patients with malignant lymphoma or multiple myeloma.

    abstract:BACKGROUND:A single injection of pegfilgrastim has been shown to be equivalent to daily filgrastim in enhancing neutrophil recovery after chemotherapy, whereas the experiences with pegfilgrastim in mobilization of peripheral blood progenitor cells (PBPCs) are limited. STUDY DESIGN AND METHODS:Forty unselected patients...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1537-2995.2006.00911.x

    authors: Kroschinsky F,Hölig K,Platzbecker U,Poppe-Thiede K,Ordemann R,Blechschmidt M,Oelschlaegel U,Schaich M,Hänel M,Bornhäuser M,Ehninger G

    更新日期:2006-08-01 00:00:00

  • Influence of climate on donor deferrals.

    abstract::The purpose of this study was to ascertain the cause for seasonal variations of donor deferral. Deferred donors and monthly temperatures from 1981 to 1984 were tallied and analyzed. Temperatures were categorized at 10-degree intervals from 15 degrees F to 75 degrees F. Donors failing the hemoglobin screening then unde...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1988.28689059031.x

    authors: Lau P,Hansen M,Sererat M

    更新日期:1988-11-01 00:00:00

  • RhCE protein variants in Southwestern Germany detected by serologic routine testing.

    abstract:BACKGROUND:Variant RHCE alleles with diminished expression of C, c, E, and e antigens have been described and indicate the genetic diversity of this gene locus in several populations. In this study the molecular background of variant RhCE antigens identified by standard serologic routine testing in German blood donors ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02220.x

    authors: Bugert P,Scharberg EA,Geisen C,von Zabern I,Flegel WA

    更新日期:2009-09-01 00:00:00

  • Exchange transfusion in sickle cell disease using a continuous-flow blood cell separator.

    abstract::An exchange transfusion was performed preoperatively on a patient with sickle cell disease using a continuous-flow blood cell separator. An exchange of 2,825 ml red blood cells achieved a hemoglobin A level of 90.8 per cent. The continuous-flow blood cell separator appears to offer a safe and effective method of excha...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1977.17377196364.x

    authors: Kernoff LM,Botha MC,Jacobs P

    更新日期:1977-05-01 00:00:00

  • Comparative morphology of granulocytes collected by three methods of leukapheresis. A light microscopy and transmission electron microscopy study.

    abstract::The morphology of granulocytes collected by continuous-flow centrifugation (CFC), discontinuous-flow centrifugation (DFC), and continuous-flow filtration (CFF) was investigated in 18 healthy donors by means of light microscopy and transmission electron microscopy. Light microscopy study of semithin sections of granulo...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1981.21582040813.x

    authors: Feliu E,Woessner S,Matutes E,Cardellach F,Grañena A,Marin P,Puig L,Vives-Corrons JL,Montserrat E,Rozman C

    更新日期:1981-09-01 00:00:00

  • Impact of donor ABH-secretor status in ABO-mismatched living donor kidney transplantation.

    abstract:BACKGROUND:The ABO blood group is a major determinant in living donor kidney transplantation since AB antigens are expressed on renal tissue. Little attention has been directed to the ABH-secretor status of the donor kidney. As renal tissue is capable of secreting soluble ABH antigens in secretors, we examined the infl...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13711

    authors: Drexler B,Holbro A,Sigle J,Gassner C,Frey BM,Schaub S,Amico P,Plattner A,Infanti L,Menter T,Mihatsch MJ,Stern M,Buser A,Dickenmann M

    更新日期:2016-09-01 00:00:00

  • A new method for monitoring the sterility of blood donation.

    abstract::Sterility of blood products is a cardinal contributor to patient safety. Bacteriologic controls of stable products comply with strict regulations, but legislation imposes only limited constraints in the case of perishable products, such as packed red cells (RBCs) or fresh-frozen plasma (FFP). Therefore, it is essentia...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1986.26386209392.x

    authors: Guéguen M,Durand F,Delamaire D,Beauplet A,Tardivel R,Genetet B,Chalumeau H,Balme MC

    更新日期:1986-05-01 00:00:00

  • Multicenter study to evaluate a new enumeration method for hematopoietic stem cell collection management.

    abstract:BACKGROUND:CD34 flow cytometry is the gold standard for stem cell enumeration in peripheral blood at the mobilization stage and in the final apheresis product. The new stem cell mode of the Sysmex XN Series analyzer enumerates an immature cell population in the white progenitor and pathological cell (WPC) channel, base...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究

    doi:10.1111/trf.14183

    authors: Grommé M,Russcher H,Braakman E,Klinkspoor JH,Dobber JA,de Greef I,de Wit NCJ

    更新日期:2017-08-01 00:00:00

  • Surveillance for Creutzfeldt-Jakob disease among persons with hemophilia.

    abstract:BACKGROUND:Although Creutzfeldt-Jakob disease (CJD) has been shown to be transmissible through blood components in rodent models, no human blood-to-blood transmission has been documented. If blood transmission were possible in humans, persons with hemophilia in the United States would be at higher risk of contracting C...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1998.38998409000.x

    authors: Evatt B,Austin H,Barnhart E,Schonberger L,Sharer L,Jones R,DeArmond S

    更新日期:1998-09-01 00:00:00

  • Adoption trends of point of issue Verax PGD rapid test for bacterial screening of platelets between 2013 and 2018 among hospitals supplied by the American Red Cross and impact on platelet availability.

    abstract:BACKGROUND:Point-of-issue tests, such as the Verax Pan Genera Detection (PGD) test, can be used to mitigate the occurrence of septic reactions. Little is known about how widespread the adoption of the PGD test is across US hospitals. STUDY DESIGN/METHODS:The Red Cross hemovigilance database was used to determine the n...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15817

    authors: Rios J,Westra J,Dy B,Young PP

    更新日期:2020-07-01 00:00:00

  • Bacterial screening of platelet components by National Health Service Blood and Transplant, an effective risk reduction measure.

    abstract:BACKGROUND:Bacterial contamination of blood components remains a major cause of sepsis in transfusion medicine. Between 2006 and 2010 in the 5 years before the introduction of bacterial screening of platelet (PLT) components by National Health Service Blood and Transplant (NHSBT), seven cases of PLT component-associate...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14085

    authors: McDonald C,Allen J,Brailsford S,Roy A,Ball J,Moule R,Vasconcelos M,Morrison R,Pitt T

    更新日期:2017-05-01 00:00:00

  • Iron supplementation by blood donors: demographics, patterns of use, and motivation.

    abstract:BACKGROUND:Iron supplements reduce the risk of iron depletion in blood donors. Recent initiatives have sought to increase use of donor iron supplementation (IS), but a baseline description of blood donor supplement practices is needed. STUDY DESIGN AND METHODS:Presenting blood donors received a questionnaire inquiring...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15407

    authors: Cable RG,Spencer BR

    更新日期:2019-09-01 00:00:00

  • A delayed transfusion reaction caused by anti-K6.

    abstract::This case report documents the demonstration of anti-K6 as the single antibody responsible for a delayed transfusion reaction. A 42-year-old white woman received three units of red blood cells for an episode of gastrointestinal bleeding from a duodenal ulcer. Twenty-three days following transfusion, laboratory and cli...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22182154223.x

    authors: Taddie SJ,Barrasso C,Ness PM

    更新日期:1982-01-01 00:00:00

  • Packed blood cells stored in AS-5 become proinflammatory during storage.

    abstract:BACKGROUND:Studies have shown that packed blood cells (PBCs) stored in AS-1 (Adsol, Baxter) and AS-3 (Nutricel, Medsep Corp.) accumulate proinflammatory substances, which may contribute to increased complications from allogeneic blood transfusion. This study assessed whether supernates from PBCs stored in AS-5 (Optisol...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02158.x

    authors: McFaul SJ,Corley JB,Mester CW,Nath J

    更新日期:2009-07-01 00:00:00

  • Risk of chikungunya virus transmission associated with European travelers returning from southern Thailand (2008-2015).

    abstract:BACKGROUND:The impact of the spread of chikungunya virus (CHIKV) by autochthonous transmission and blood transfusion in nonendemic areas via travelers returning from CHIKV-affected locations is a concern. METHODS:We analyzed the risks of potential CHIKV importation and transfusion transmission from Thailand to Europe ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15401

    authors: Appassakij H,Khuntikij P,Silpapojakul K,Promwong C,Rujirojindakul P,Suddeaugrai O,Chullasara A

    更新日期:2019-08-01 00:00:00

  • Acute hepatitis B virus window-period blood donations detected by individual-donation nucleic acid testing: a report on the first two cases found and interdicted in Spain.

    abstract:BACKGROUND:Mathematical models predict that, in Spain, a significant number of blood units will be obtained during the window period of the hepatitis B virus (HBV) infection. Routine nucleic acid testing (NAT) on individual blood units may provide experimental data to evaluate such a theoretical risk. STUDY DESIGN AND...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2006.00863.x

    authors: González R,Echevarria JM,Avellón A,Barea L,Castro E

    更新日期:2006-07-01 00:00:00

  • Improvement in appropriate autologous donations with local education: 1987 to 1989.

    abstract::Preoperative autologous blood donation for elective surgery patients at university hospitals was underused in the past. More recently, national educational efforts have been made. To test the impact of local surgeon interviews and education, in 1988 the same local educational program was instituted at three university...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1992.32692367202.x

    authors: Toy PT,McVay PA,Strauss RG,Stehling LC,Ahn DK

    更新日期:1992-07-01 00:00:00

  • Bloodless medicine: current strategies and emerging treatment paradigms.

    abstract:BACKGROUND:Advances in our understanding of the risks associated with allogeneic blood transfusions (ABTs) and the growing number of patients who wish to avoid ABTs have led to the emergence of new treatment paradigms for "bloodless" medicine and surgery. STUDY DESIGN AND METHODS:Here, we review prior studies and summ...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.13736

    authors: Resar LM,Wick EC,Almasri TN,Dackiw EA,Ness PM,Frank SM

    更新日期:2016-10-01 00:00:00

  • Blood donation on posters: a worldwide review.

    abstract::Originally pasted on walls and on locations reserved specially for that purpose, the poster is a medium for advertising and promotion to be seen on the streets and in public places. More recently, it has spread, in a smaller format, on dedicated indoor sites: billboards, columns, street furniture, and so forth. For tr...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2011.03422.x

    authors: Lefrère JJ,Danic B

    更新日期:2012-06-01 00:00:00

  • Additional red blood cell alloantibodies after blood transfusions in a nonhematologic alloimmunized patient cohort: is it time to take precautionary measures?

    abstract:BACKGROUND:Red blood cell (RBC) alloimmunization is common in transfused patients. Most studies report on the rate of alloimmunization in chronically transfused patients, which can be as high as 60 percent. Less is known on the incidence of clinically relevant antibodies in accidentally transfused patients. Because the...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1537-2995.2006.00764.x

    authors: Schonewille H,van de Watering LM,Brand A

    更新日期:2006-04-01 00:00:00

  • First report of using low-titer cold-stored type O whole blood in massive postpartum hemorrhage.

    abstract:BACKGROUND:In cases of massive hemorrhage in the US military, improved outcomes have been reported with the use of warm, fresh whole blood transfusions. Cold-stored low-titer type O whole blood (LTOWB) has become the preferred product for resuscitation of severe bleeding in deployed surgical units. Reports of LTOWB use...

    journal_title:Transfusion

    pub_type:

    doi:10.1111/trf.15492

    authors: Bahr TM,DuPont TL,Morris DS,Pierson SE,Esplin MS,Brown SM,O'Brien EA,Ilstrup SJ,Christensen RD

    更新日期:2019-10-01 00:00:00

  • Blood screening nucleic acid amplification tests for human immunodeficiency virus Type 1 may require two different amplification targets.

    abstract:BACKGROUND:Five cases of human immunodeficiency virus Type 1 (HIV-1) RNA-positive blood donations are described that escaped detection by three different CE-marked nucleic acid amplification technique (NAT) screening assays. These events were associated with two HIV-1 transmissions to recipients of blood components. Th...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03281.x

    authors: Chudy M,Weber-Schehl M,Pichl L,Jork C,Kress J,Heiden M,Funk MB,Nübling CM

    更新日期:2012-02-01 00:00:00

  • The effect of recombinant human erythropoietin on the efficacy of autologous blood donation in patients with low hematocrits: a multicenter, randomized, double-blind, controlled trial.

    abstract:BACKGROUND:This randomized controlled study was undertaken to determine the effect of recombinant human erythropoietin (rHuEPO) on erythropoiesis, autologous blood collection, and allogeneic transfusion risk in elective surgery patients with low baseline hematocrits. STUDY DESIGN AND METHODS:Patients (n = 204) with lo...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1046/j.1537-2995.1996.36196190512.x

    authors: Price TH,Goodnough LT,Vogler WR,Sacher RA,Hellman RM,Johnston MF,Bolgiano DC,Abels RI

    更新日期:1996-01-01 00:00:00

  • Coagulopathy after traumatic brain injury: incidence, pathogenesis, and treatment options.

    abstract::Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful predictor related to outcome and prognosis. The complex pathophysiological mechanisms of the coagulopathy of TBI are multifactorial and remain still undefined. The nature of the coagulation abnormalities differs between severe TBI an...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.12033

    authors: Maegele M

    更新日期:2013-01-01 00:00:00