The effect of adenine on platelet storage.

Abstract:

:Adenine is an approved additive to citrate-phosphate-dextrose anticoagulant for whole blood collection and extends the storage life of red blood cells. We used in vitro methods to investigate the effects of adenine on platelet function and viability during 72 hours of storage at 22 degrees C. Although the hypotonic shock response and aggregation were decreased, these effects were reversed following separation and resuspension in fresh adenine-free plasma. Serotonin uptake and release were not affected by adenine, however malonaldehyde formation was slightly enhanced. Glucose, pH and pO2 levels were lower, while lactate levels were slightly higher than in platelets stored without adenine. These results indicate little in vitro effect of adenine on platelets stored as platelet-rich plasma or platelet concentrate.

journal_name

Transfusion

journal_title

Transfusion

authors

Wong SC,Rock G

doi

10.1046/j.1537-2995.1982.22482251208.x

subject

Has Abstract

pub_date

1982-07-01 00:00:00

pages

283-7

issue

4

eissn

0041-1132

issn

1537-2995

journal_volume

22

pub_type

杂志文章
  • Impact of a policy to permit the return of donors repeat-reactive to the Abbott PRISM antibody to hepatitis B core antigen assay.

    abstract:BACKGROUND:The expected donor loss from recent implementation of antibody to hepatitis B core antigen (anti-HBc) testing in Canada was uncertain but potentially significant based on US experience. To reduce donor loss from false-reactive tests, repeat-reactive donors without other evidence of infection were eligible to...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01973.x

    authors: O'Brien SF,Yi QL,Fan W,Fearon MA,Scalia V,Goldman M

    更新日期:2009-02-01 00:00:00

  • Detecting failed WBC-reduction processes: computer simulations of intermittent and continuous process failure.

    abstract:BACKGROUND:By regulation, ongoing process control of WBC-reduced processes is performed on 1 percent of WBC-reduced components, typically four to five samples per month. However, prospective study of the power of this small sample has been difficult. Using computer-generated "residual WBC" distributions, sample size se...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2000.40121427.x

    authors: Adams MR,Fisher DM,Dumont LJ,Dzik WH,Heaton WA

    更新日期:2000-12-01 00:00:00

  • An apparent anti-Jka reacting only in the presence of methyl esters of hydroxybenzoic acid.

    abstract::An apparent anti-Jka, reacting only in the presence of methyl esters of hydroxybenzoic acid (HBA), was detected in an individual with Jk (a+) red blood cells. The antibody was first detected when a commercial low-ionic-strength-solution preparation containing the preservative methyl paraben (a methyl ester of hydroxyb...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22683068617.x

    authors: Halima D,Garratty G,Bueno R

    更新日期:1982-11-01 00:00:00

  • Effect of repeat transfusion exposure on plasma cytokine and markers of endothelial activation in the extremely preterm neonate.

    abstract:BACKGROUND:Very preterm newborns receive up to three to five red blood cell (RBC) transfusions, often early, after birth. Despite awareness of the association of transfusion with increases in cytokines and markers of endothelial activation, research has focused on single transfusions weeks after birth. With pathophysio...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15952

    authors: Crawford TM,Andersen CC,Stark MJ

    更新日期:2020-07-25 00:00:00

  • The crossmatch. A brief historical perspective.

    abstract::First described in 1907, the crossmatch has been in a constant state of modification since that time. Major milestones in the evolution of the test include demonstration of the relative importance of red blood cell typing and of the matching test, development of rapid techniques for the test, advent of high protein, a...

    journal_title:Transfusion

    pub_type: 历史文章,杂志文章

    doi:10.1046/j.1537-2995.1981.21682085750.x

    authors: Oberman HA

    更新日期:1981-11-01 00:00:00

  • Demonstration of gene dosage effects on antigens in the Duffy, Ss, and Rh systems using an enzyme-linked immunosorbent assay.

    abstract::Using a recently developed enzyme-linked immunosorbent assay, gene dosage effects were demonstrated for the Duffy, Ss, and Rh red blood cell antigen systems. We report a comparison by an antibody-binding assay of the relative amounts of Fya and Fyb antigens on FyaFya, FyaFyb, FybFyb, FyaFyx, and FyxFyx erthrocytes, an...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22683068606.x

    authors: Caren LD,Bellavance R,Grumet FC

    更新日期:1982-11-01 00:00:00

  • Comparison of human umbilical cord blood processing with or without hydroxyethyl starch.

    abstract:BACKGROUND:Umbilical cord blood (UCB) processing with hydroxyethyl starch (HES) is the most common protocol in the cord blood banks. The quality of UCB volume reduction was guaranteed by minimum manipulation of cord blood samples in the closed system. This study aimed to analyze and compare cell recovery and viability ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14290

    authors: Souri M,Nikougoftar Zarif M,Rasouli M,Golzadeh K,Nakhlestani Hagh M,Ezzati N,Atarodi K

    更新日期:2017-11-01 00:00:00

  • The effects of combined platelet and leukapheresis on the blood coagulation system.

    abstract::Analysis of blood coagulation was done on samples of blood collected from ten donors undergoing combined platelet and leukapheresis using the Haemonetics Model 30 Blood Processor. Blood samples were obtained from the donors prior to, during, and following pheresis. Blood was also obtained from the blood-return line af...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1979.19279160288.x

    authors: Kisker CT,Strauss RG,Koepke JA,Maguire LC,Thompson JS

    更新日期:1979-03-01 00:00:00

  • Red blood cell alloimmunization in transfused patients with bone marrow failure syndromes.

    abstract:BACKGROUND:Red blood cell (RBC) alloimmunization is a concern for patients who receive multiple or chronic transfusions. Alloimmunization prevalence in transfused patients with bone marrow failure syndrome (BMFS) is unknown. This study aimed to determine physician practice for RBC antigen matching, immunization rates, ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13608

    authors: Cohen D,Hartung H,Evans P,Friedman DF,Chou ST

    更新日期:2016-06-01 00:00:00

  • Noninvasive determination of fetal RHD status by examination of cell-free DNA in maternal plasma.

    abstract:BACKGROUND:Cell-free fetal DNA in maternal plasma opens the way for routine risk-free diagnosis of fetal D status of D- mothers. The focus was on accuracy of RHD typing and confirmation of fetal DNA in maternal plasma while RHD was not detected. STUDY DESIGN AND METHODS:Plasma DNA was extracted (by manual and/or autom...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.00559.x

    authors: Brojer E,Zupanska B,Guz K,Orziñska A,Kaliñska A

    更新日期:2005-09-01 00:00:00

  • Resolution of a serum sample mix-up through the use of short tandem repeat DNA typing.

    abstract:BACKGROUND:A sample mix-up occurred in a tissue procurement laboratory in which aliquots of serum from two tissue donors were accidentally mislabeled. The clues to the apparent mixup involved discrepant Hepatitis C test results. In an attempt to resolve the apparent mix up, DNA typing was performed using serum samples ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.0041-1132.2004.04212.x

    authors: Allen RW,Pritchard JK

    更新日期:2004-12-01 00:00:00

  • Inactivation of Japanese encephalitis virus in plasma by methylene blue combined with visible light and in platelet concentrates by ultraviolet C light.

    abstract::Japanese encephalitis virus (JEV) is endemic to tropical areas in Asia and the Western Pacific. It can cause fatal encephalitis, although most infected individuals are asymptomatic. JEV is mainly transmitted to humans through the bite of an infected mosquito, but can also be transmitted through blood transfusion. To m...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.16021

    authors: Rustanti L,Hobson-Peters J,Colmant AMG,Hall RA,Young PR,Reichenberg S,Tolksdorf F,Sumian C,Gravemann U,Seltsam A,Marks DC,Faddy HM

    更新日期:2020-11-01 00:00:00

  • Epitope mapping of antibodies directed against the human neutrophil alloantigen 3a.

    abstract:BACKGROUND:Severe transfusion-related acute lung injury is often caused by antibodies directed against the human neutrophil alloantigen (HNA)-3a. HNA-3a results from an amino acid exchange (Arg154Gln) in the first extracellular loop of the choline transporter-like protein 2 (CTL2). The characteristics of the binding do...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03115.x

    authors: Berthold T,Wesche J,Kuhnert K,Fürll B,Hippe H,Hoppen J,Reil A,Muschter S,Bux J,Greinacher A

    更新日期:2011-10-01 00:00:00

  • Inositol hexaphosphate-loaded red blood cells prevent in vitro sickling.

    abstract:BACKGROUND:Hypoxia is a major cause of painful vaso-occlusive crisis in sickle cell disease (SCD). Simple transfusion and red blood cell (RBC) exchange are commonly used as preventive therapies whose aim is to dilute hemoglobin (Hb)S-containing RBCs (SS-RBCs) with normal RBCs (AA-RBCs) to prevent sickling. We hypothesi...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02663.x

    authors: Bourgeaux V,Hequet O,Campion Y,Delcambre G,Chevrier AM,Rigal D,Godfrin Y

    更新日期:2010-10-01 00:00:00

  • Persistence of cefotetan on red blood cells.

    abstract:BACKGROUND:Cefotetan can cause severe immune hemolytic anemia that may persist long after the drug is discontinued. To study the binding of cefotetan to RBCs, patients who received cefotetan were followed and tested for the presence of antibody to cefotetan. STUDY DESIGN AND METHODS:Patients receiving cefotetan were i...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.03360.x

    authors: Davenport RD,Judd WJ,Dake LR

    更新日期:2004-06-01 00:00:00

  • Quantity, quality, and functionality of peripheral blood cells derived from residual blood of different apheresis kits.

    abstract:BACKGROUND:Research with primary human white blood cell (WBC) subpopulations requires high quantity, quality, and functionality of peripheral blood mononuclear cells (PBMCs) as a source to further characterize cellular subpopulations such as T and B lymphocytes, monocytes, or natural killer cells. Apart from buffy coat...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14616

    authors: Knörck A,Marx S,Friedmann KS,Zöphel S,Lieblang L,Hässig C,Müller I,Pilch J,Sester U,Hoth M,Eichler H,Sester M,Schwarz EC

    更新日期:2018-06-01 00:00:00

  • Routine bacterial screening of apheresis platelets on Day 4 using a rapid test: a 4-year single-center experience.

    abstract:BACKGROUND:The platelet (PLT) Pan Genera Detection test (PGD) is a rapid bacterial detection system used to screen PLTs for bacterial contamination. We report a single center 46-month experience with secondary screening of apheresis PLTs by PGD testing. STUDY DESIGN AND METHODS:Existing testing records of apheresis PL...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12083

    authors: Dunbar NM,Kreuter JD,Marx-Wood CR,Dumont LJ,Szczepiorkowski ZM

    更新日期:2013-10-01 00:00:00

  • Hematopoietic cell infusion-related adverse events in pediatric/small recipients in a prospective/multicenter study.

    abstract:BACKGROUND:Hematopoietic cell infusion-related adverse events (HCI-AEs) in hematopoietic stem cell transplantations (HSCTs) have been largely attributed to toxicity of dimethyl sulfoxide (DMSO) for cryopreservation, but HSC products also contain various cells and plasma components. Our recent prospective study of 1125 ...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/trf.15786

    authors: Ikeda K,Ohto H,Yamada-Fujiwara M,Okuyama Y,Fujiwara SI,Muroi K,Mori T,Kasama K,Kanamori H,Iseki T,Nagamura-Inoue T,Kameda K,Kanda J,Nagai K,Fujii N,Ashida T,Hirose A,Takahashi T,Minakawa K,Tanosaki R

    更新日期:2020-05-01 00:00:00

  • Incidence of breakage of human RBCs frozen with 40-percent wt/vol glycerol using two different methods for storage at -80 degrees C.

    abstract:BACKGROUND:We reported previously that the incidence of breakage was 34.2 percent when human RBCs were frozen with 40-percent wt/vol glycerol in polyolefin plastic bags stored in aluminum containers at -80 degrees C and subjected to transportation. When human RBCs were frozen with 40-percent wt/vol glycerol at -80 degr...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00317.x

    authors: Valeri CR,Lane JP,Srey R,Ragno G

    更新日期:2003-03-01 00:00:00

  • The role of the paternal health history in cord blood banking.

    abstract:BACKGROUND:Umbilical cord blood (UCB) transplantation is becoming more widely used, yet ethical and policy issues regarding consent and health history persist. Whereas most UCB banks do not require paternal consent or paternal health history (PHH), both are obtained at this institution whenever possible. This study ass...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00188.x

    authors: Askari S,Miller J,Clay M,Moran S,Chrysler G,McCullough J

    更新日期:2002-10-01 00:00:00

  • Effective use of a strategy using assigned red cell units to limit donor exposure for neonatal patients.

    abstract::Critically ill neonatal infants receive frequent small-volume red cell (RBC) transfusions for replacement of blood drawn for laboratory analysis or for treatment of symptomatic anemia secondary to underlying medical conditions and/or a relative bleeding diathesis. Retrospective review of transfusion practice in a hosp...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1993.33593255596.x

    authors: Cook S,Gunter J,Wissel M

    更新日期:1993-05-01 00:00:00

  • Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS-III-Omics.

    abstract:BACKGROUND:Biological and technical variability has been increasingly appreciated as a key factor impacting red blood cell (RBC) storability and, potentially, transfusion outcomes. Here, we performed metabolomics analyses to investigate the impact of factors other than storage duration on the metabolic phenotypes of st...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14979

    authors: D'Alessandro A,Culp-Hill R,Reisz JA,Anderson M,Fu X,Nemkov T,Gehrke S,Zheng C,Kanias T,Guo Y,Page G,Gladwin MT,Kleinman S,Lanteri M,Stone M,Busch M,Zimring JC,Recipient Epidemiology and Donor Evaluation Study-III (REDS-

    更新日期:2019-01-01 00:00:00

  • Acute lung injury after blood transfusion in mechanically ventilated patients.

    abstract:BACKGROUND:Liberal transfusion strategy increases the risk of acute lung injury (ALI), but specific transfusion-related factors have not been characterized. We tested the hypotheses that storage age and specific type of blood products are associated with increased risk of ALI in mechanically ventilated patients. STUDY...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.04053.x

    authors: Gajic O,Rana R,Mendez JL,Rickman OB,Lymp JF,Hubmayr RD,Moore SB

    更新日期:2004-10-01 00:00:00

  • Platelet preservation. IV. Preparation and cryopreservation of platelet concentrates from fresh and overnight-stored human blood.

    abstract::Two methods were used for the preparation of platelet concentrates from fresh and overnight-stored human ACD blood. In a two-step method prostoglandin E1 was added to platelet rich plasma and the mixture was centrifuged to obtain platelet concentrate. The IBM 2991 Blood Cell Processor was used in a one-step method. Th...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1978.18178118562.x

    authors: Odink J,de Wit JJ,Janssen CL,Prins HK

    更新日期:1978-01-01 00:00:00

  • Uneventful administration of plasma products in a recipient with T-activated red cells.

    abstract::A patient with T-polyagglutinable red cells and a severe coagulopathy provided an opportunity to observe the results of plasma transfusion in the face of T-activation. The patient was a 52-year-old Navajo Indian with a perforated gall bladder and related sepsis due to Clostridium perfringens. The gall bladder was remo...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1986.26286152912.x

    authors: Eversole M,Nonemaker B,Zurek K,South S,Simon T

    更新日期:1986-03-01 00:00:00

  • Lengths of hepatitis B viremia and antigenemia in blood donors: preliminary evidence of occult (hepatitis B surface antigen-negative) infection in the acute stage.

    abstract:BACKGROUND:The Japanese Red Cross (JRC) implemented a fully automated pooling and nucleic acid amplification test (NAT) system for testing seronegative donations. The JRC sample repository and repeat blood donations allowed for lookback and follow-up studies of hepatitis B virus (HBV) DNA-positive donors, who tested ne...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01234.x

    authors: Yoshikawa A,Gotanda Y,Minegishi K,Taira R,Hino S,Tadokoro K,Ohnuma H,Miyakawa K,Tachibana K,Mizoguchi H,Japanese Red Cross NAT Screening Research Group.

    更新日期:2007-07-01 00:00:00

  • Alteration of red cell aggregability and shape during blood storage.

    abstract:BACKGROUND:Storage of blood units (for 35-42 days, depending on the preservative solution) has been reported to induce changes (e.g., reduction of sialic acid level) in red cells that are expected to alter their aggregability. STUDY DESIGN AND METHODS:The aggregability of stored red cells was monitored in their autolo...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1999.39399219284.x

    authors: Hovav T,Yedgar S,Manny N,Barshtein G

    更新日期:1999-03-01 00:00:00

  • A comparative study of reducing the extracellular potassium concentration in red blood cells by washing and by reduction of additive solution.

    abstract:BACKGROUND:Extracellular potassium concentration (K(+)) increases in the supernatant of whole and packed red blood cell units (pRBCs) with duration of refrigerated storage in citrate-phosphate-dextrose-adenine (CPDA-1) and additive solution (AS). Studies have shown that to avoid hyperkalemia, washed pRBCs are preferred...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01095.x

    authors: Bansal I,Calhoun BW,Joseph C,Pothiawala M,Baron BW

    更新日期:2007-02-01 00:00:00

  • Transfusion-induced serum sickness.

    abstract:BACKGROUND:Transfusion-induced serum sickness reactions are rarely reported in the literature. The Type III hypersensitivity reaction to heterologous proteins involves deposition of complement and immune complexes in small vessel walls resulting in a leukocytoclastic vasculitis. A case of a multiply transfused patient ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01956.x

    authors: Saegeman V,Wynendaele W,Kerre S,Dedeurwaerdere F,Van den Driessche M,Moerman J

    更新日期:2009-02-01 00:00:00

  • A novel A allele with 664G>A mutation identified in a family with the Am phenotype.

    abstract:BACKGROUND:The Am phenotype has been characterized as a weak expression of the A antigen on red blood cells but the presence of a normal quantity of the A antigen in saliva. This study describes a molecular genetic analysis of members of an Am family. STUDY DESIGN AND METHODS:The eight exon regions of the ABO genes of...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.04132.x

    authors: Lin M,Hou MJ,Twu YC,Yu LC

    更新日期:2005-01-01 00:00:00