Clinical and laboratory findings on two patients with naturally occurring anti-Kell agglutinins.

abstract：:As an adjunct to antibiotic therapy, granulocytes for infusion often are required within hours of the diagnosis of neonatal sepsis. The logistics of obtaining granulocytes by leukapheresis were evaluated in order to provide, at short notice, a low volume, highly concentrated product. An average of 4.0 X 10(9) granuloc...

journal_title：Transfusion

authors： Kalmin ND,Liles BA

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Development of de novo alloantibodies against recipient's red blood cell (RBC) antigens by engrafted donor's lymphocytes is a known phenomenon in the setting of allogeneic hematopoietic stem cell transplantation (HSCT). This situation is usually clinically insignificant. We report a case of early clinically ...

journal_title：Transfusion

authors： Bailén R,Kwon M,Pérez-Corral AM,Pascual C,Buño I,Balsalobre P,Serrano D,Gayoso J,Díez-Martín JL,Anguita J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) transfusions are essential for patients who are bleeding or have an increased risk of bleeding due to a decreased number or abnormal function of circulating PLTs. A shelf life of 5 days for PLT products presents an inventory management challenge. In 2006, greater than 10% of apheresis PLTs mad...

journal_title：Transfusion

authors： Fuller AK,Uglik KM,Braine HG,King KE

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Liberal transfusion strategy increases the risk of acute lung injury (ALI), but specific transfusion-related factors have not been characterized. We tested the hypotheses that storage age and specific type of blood products are associated with increased risk of ALI in mechanically ventilated patients. STUDY...

journal_title：Transfusion

authors： Gajic O,Rana R,Mendez JL,Rickman OB,Lymp JF,Hubmayr RD,Moore SB

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Radiation and filtration have achieved satisfactory results in inactivation or removal of tumor cells mixed in salvage blood, but some drawbacks remain. This study evaluated the inactivation on HCT116 cells mixed in simulative salvage blood by riboflavin photochemical treatment. METHODS:HCT116 cells were ad...

journal_title：Transfusion

authors： Yu Y,Yang L,He C,Tai S,Ma C,Yang T,Wang D

更新日期：2019-10-01 00:00:00

abstract：:Kell blood-group-active protein has been isolated by labeling red cell surface proteins with 125I, sensitizing intact cells with anti-K1, anti-K2, anti-K7, or anti-K22, solubilizing the cell membranes, isolating immune complexes, and separating their components by sodium dodecyl sulfate polyacrylamide gel electrophore...

journal_title：Transfusion

authors： Redman CM,Marsh WL,Mueller KA,Avellino GP,Johnson CL

更新日期：1984-03-01 00:00:00

abstract：:A non-diethylhexyl phthalate (DEHP)-plasticized blood bag for 5-day storage of random-donor platelet concentrates has been developed. The plastic bag is composed of polyvinylchloride plastic with a butyryl trihexyl citrate plasticizer. The suitability of this plastic for the storage of platelet concentrates for use in...

journal_title：Transfusion

authors： Snyder EL,Aster RH,Heaton A,Grode G,Napychank P,Kagen L,Jefferies LC,Hedberg S,Buchholz DH

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Hypothermic storage transforms red blood cells (RBC) from smooth biconcave discocytes into increasingly spherical spiculated echinocytes and, ultimately, fragile spherocytes (S). Individual cells undergo this transformation at different rates, producing a heterogeneous mixture of RBCs at all stages of echino...

journal_title：Transfusion

authors： Lu M,Shevkoplyas SS

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Clinical outcomes in transfused patients may be affected by the duration of blood storage, possibly due to red blood cell (RBC)-mediated disruption of nitric oxide (NO) signaling, a key regulator of vascular tone and blood flow. STUDY DESIGN AND METHODS:AS-1 RBC units stored up to 42 days were sampled at se...

journal_title：Transfusion

authors： Alexander JT,El-Ali AM,Newman JL,Karatela S,Predmore BL,Lefer DJ,Sutliff RL,Roback JD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The relationship between length of storage of red blood cell (RBC) units and biochemical changes has been well studied, but little is known about the progression of cellular immunomodulative properties in blood recipients. This study aims to quantify in vitro T-cell activation and cytokine release by white b...

journal_title：Transfusion

authors： Karam O,Tucci M,Toledano BJ,Robitaille N,Cousineau J,Thibault L,Lacroix J,Le Deist F

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:When problems with compatibility beyond ABO and D arise, currently transfusion services search their inventories and perform time-consuming serologic testing to locate antigen-negative blood. These clinically important blood group antigens can be detected reliably by red cell genotyping, which is a technolog...

journal_title：Transfusion

authors： Flegel WA,Gottschall JL,Denomme GA

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The disappearance of anti-HCV antibodies over time, after a self-limited infection, also referenced seroreversion, has been observed. The frequency of this phenomenon remains controversial, especially in immunocompetent subjects. However, it has important implications in the context of transfusion inquiries,...

journal_title：Transfusion

authors： Lefrère JJ,Girot R,Lefrère F,Guillaume N,Lerable J,Le Marrec N,Bouchardeau F,Laperche S

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Cord blood (CB) is a widely accepted stem cell source and its clinical utilization depends, to a great extent, on its cell content. Birth-to-clamping (BTC) time of umbilical cord determines placental transfusion to the newborn, and the remaining blood that can be collected and banked. The 2017 Committee Opin...

journal_title：Transfusion

authors： Ciubotariu R,Scaradavou A,Ciubotariu I,Tarnawski M,Lloyd S,Albano M,Dobrila L,Rubinstein P,Grunebaum A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Deterioration in quality of platelet concentrates (PCs) during storage results from the appearance of storage lesions affecting the hemostatic functions and posttransfusion survival of platelets. These lesions depend on the preparation and pathogen inactivation methods used, duration of storage, and platelet...

journal_title：Transfusion

authors： Isola H,Ravanat C,Rudwill F,Pongerard A,Haas D,Eckly A,Gachet C,Hechler B

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Blood component irradiation is an accepted method of preventing transfusion-associated GVHD. Previous publications have largely focused on the technical aspects of the irradiation process itself, but relatively little attention has been paid to the details associated with the implementation of a blood irradi...

journal_title：Transfusion

authors： Patton GA,Skowronski MG

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:The correlation between signal-to-cutoff (S/CO) ratios of a second-generation hepatitis C virus (HCV) enzyme immunoassay (EIA; Abbott) and a third-generation HCV enzyme-linked immunosorbent assay (ELISA; Ortho) and confirmed HCV infection has been reported. The utility of the values for the Chinese anti-HCV ...

journal_title：Transfusion

authors： Ren FR,Lv QS,Zhuang H,Li JJ,Gong XY,Gao GJ,Liu CL,Wang JX,Yao FZ,Zheng YR,Zhu FM,Tiemuer MH,Bai XH,Shan H

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Current blood transfusion standards in Canada and the United States permit transfusion of ABO-nonidentical platelets when ABO-identical platelets are not available. This practice increases the availability of platelets, a component in chronic shortage in Ontario, Canada because of the 5-day shelf-life. The i...

journal_title：Transfusion

authors： Lin Y,Callum JL,Coovadia AS,Murphy PM

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Intraoperative and postoperative red blood cell (RBC) transfusions are relatively frequent events tracked in the American College of Surgeons' National Surgical Quality Improvement Program-Pediatric (ACS-NSQIP-P). This study sought to quantify variation in RBC transfusion practices among hospitals. STUDY DE...

journal_title：Transfusion

authors： Stey AM,Vinocur CD,Moss RL,Hall BL,Cohen ME,Kraemer K,Ko CY,Kenney BD

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Intracellular glutathione declines progressively in platelet concentrates stored for transfusion, but little is known about the nature of this process. STUDY DESIGN AND METHODS:Acivicin, an irreversible inhibitor of gamma-glutamyl transpeptidase, was used to determine the fate of glutathione lost from plate...

journal_title：Transfusion

authors： Burch PT,Aman M,Burch JW

更新日期：1994-05-01 00:00:00

abstract：:The enzyme-linked antiglobulin test was used to determine the percentage of antibody removed from sensitized red cells by five elution methods: Rubin ether, xylene, digitonin-acid, glycine, and heat. Antibodies examined in the study included anti-D, -c, -E, and -K. With two examples of anti-D, more antibody was eluted...

journal_title：Transfusion

authors： Gibble JW,Salamon JL,Ness PM

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Unexpected neonatal alloimmune thrombocytopenia (NAIT) may have devastating consequences and its management is challenging. To design future trials, evidence from the literature and existing best practice need review. STUDY DESIGN AND METHODS:This study was a cross-sectional survey of neonatal units in Germ...

journal_title：Transfusion

authors： Bassler D,Greinacher A,Okascharoen C,Klenner A,Ditomasso J,Kiefel V,Chan A,Paes B

更新日期：2008-01-01 00:00:00

abstract：:A patient with T-polyagglutinable red cells and a severe coagulopathy provided an opportunity to observe the results of plasma transfusion in the face of T-activation. The patient was a 52-year-old Navajo Indian with a perforated gall bladder and related sepsis due to Clostridium perfringens. The gall bladder was remo...

journal_title：Transfusion

authors： Eversole M,Nonemaker B,Zurek K,South S,Simon T

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Effective donor skin disinfection is essential in preventing bacterial contamination of blood components with skin flora bacteria like Staphylococcus epidermidis. Cell aggregates of S. epidermidis (biofilms) are found on the skin and are resistant to the commonly used donor skin disinfectants chlorhexidine-g...

journal_title：Transfusion

authors： Alabdullatif M,Boujezza I,Mekni M,Taha M,Kumaran D,Yi QL,Landoulsi A,Ramirez-Arcos S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Patients with acute myeloid leukemia (AML) with hyperleukocytosis of at least 100 x 10(9) per L are at high risk of early death due to pulmonary or cerebral leukostasis. Although the efficacy of leukapheresis in terms of prompt cytoreduction is generally accepted, published data regarding the clinical value ...

journal_title：Transfusion

authors： Bug G,Anargyrou K,Tonn T,Bialleck H,Seifried E,Hoelzer D,Ottmann OG

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The absence of hybrid Rhesus boxes denotes an RHD homozygous status and helps to detect the presence of Dce haplotypes instead of dce. RHCE exon 1 C48, characteristic of RHC alleles, and RHCE exon 5 G733, responsible for VS antigenicity, have been noted in many RHce alleles but it was not clearly established...

journal_title：Transfusion

authors： Cotorruelo CM,Munini GM,García Borrás SE,Racca LL,Biondi CS,Racca AL

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:This study investigated the effects of a 6-month deferral due to low hemoglobin (Hb) on the subsequent donation patterns of Australian whole blood donors. STUDY DESIGN AND METHODS:The study was a retrospective cohort study of the donation patterns of all whole blood donors deferred for low Hb during a 2-mon...

journal_title：Transfusion

authors： Hillgrove T,Moore V,Doherty K,Ryan P

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Hemolysis of red blood cells (RBCs) during blood bank storage is the most obvious manifestation of RBC storage system failure. However, its analysis is made difficult because the largest source of interunit difference is donor specific. Availability of data from national blood systems on large numbers of RBC...

journal_title：Transfusion

authors： Hess JR,Sparrow RL,van der Meer PF,Acker JP,Cardigan RA,Devine DV

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:After multiple transfusions, the serologic typing of autologous blood group phenotypes is difficult, because of mixed RBC populations. The genotyping of ABO, Rh, Kell, Kidd, and Duffy systems could be used to determine autologous blood group antigen status. STUDY DESIGN AND METHODS:Blood samples from patien...

journal_title：Transfusion

authors： Rozman P,Dovc T,Gassner C

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Alloimmunization against human platelet antigens (HPAs) during pregnancy is rare but can lead to severe bleeding disorders, such as fetal and neonatal alloimmune thrombocytopenia. STUDY DESIGN AND METHODS:In a cohort of 241 uncomplicated pregnancies, we investigated the immunogenicity of HPA mismatches and ...

journal_title：Transfusion

authors： Reiher VSA,Hönger G,Infanti L,Passweg JR,Hösli I,Frey BM,Gassner C,Meyer S,Buser AS,Holbro A,Schaub S

更新日期：2017-05-01 00:00:00

abstract：:Leukapheresis by continuous flow centrifugation (CFC) or filtration (FL) were compared in untreated and corticosteroid-treated donors. The administration of prednisone 60 mg orally 10 to 12 hours before leukapheresis increased significantly both the donor's prepheresis WBC counts and the total granulocyte yields by CF...

journal_title：Transfusion

authors： MacPherson JL,Nusbacher J,Bennett JM

更新日期：1976-05-01 00:00:00