Red blood cell hemolysis during blood bank storage: using national quality management data to answer basic scientific questions.

abstract：BACKGROUND:Donor granulocyte concentrates are routinely administered to patients with granulocyte function defects or transient neutropenia and (risk of) bacterial or fungal exacerbations, despite lack of definitive clinical proof for patient-relevant outcome improvement. Granulocytes are collected by apheresis from he...

journal_title：Transfusion

authors： Thorausch K,Schulz M,Bialleck H,Luxembourg B,Seifried E,Bonig H

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:In spite of interventions, approximately 1000 per 1,000,000 platelet (PLT) collections are contaminated with bacteria at collection. The current prestorage culture procedure at some blood centers is to inoculate a fixed volume from the collection bag (4-8 mL) regardless of collection volume. The sensitivity ...

journal_title：Transfusion

authors： Tomasulo PA,Wagner SJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:A novel apheresis procedure for a blood separator (MCS+, Haemonetics) enables the collection of 2 WBC-reduced RBC units in a single donation by using one disposable set with one in-line WBC-reduction filter (RC2H, Pall Corp.). The objective of this study was to evaluate the filtration performance in connecti...

journal_title：Transfusion

authors： Bandarenko N,Rose M,Kowalsky RJ,Baston RK,Brecher ME,Elfath MD,Whitley P,Heminway M,Holme S

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Hypoxia is a major cause of painful vaso-occlusive crisis in sickle cell disease (SCD). Simple transfusion and red blood cell (RBC) exchange are commonly used as preventive therapies whose aim is to dilute hemoglobin (Hb)S-containing RBCs (SS-RBCs) with normal RBCs (AA-RBCs) to prevent sickling. We hypothesi...

journal_title：Transfusion

authors： Bourgeaux V,Hequet O,Campion Y,Delcambre G,Chevrier AM,Rigal D,Godfrin Y

更新日期：2010-10-01 00:00:00

abstract：:Prospective-concurrent audits and medical consultation were associated with a 56 percent decrease in the use of platelet concentrates at a tertiary care medical center. This study documents that mandatory pretransfusion review of component requests can alter hospital transfusion practices. ...

journal_title：Transfusion

authors： Simpson MB

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Platelet concentrates (PCs) are the most common blood components eliciting nonhemolytic transfusion reactions (NHTRs), such as allergic transfusion reactions and febrile reactions. However, the precise mechanisms of NHTRs in PC transfusion remain largely unknown. Previous studies reported that mitochondria-d...

journal_title：Transfusion

authors： Yasui K,Matsuyama N,Kuroishi A,Tani Y,Furuta RA,Hirayama F

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Because the frequency of umbilical cord blood (UCB) stem cell transplantation has increased, the quality of UCB available in banks is an important part of the success of UCB stem cell transplants. STUDY DESIGN AND METHODS:A quality assurance monitoring system was used to evaluate 268 UCB units provided to u...

journal_title：Transfusion

authors： McCullough J,McKenna D,Kadidlo D,Schierman T,Wagner J

更新日期：2005-06-01 00:00:00

abstract：:Each of 20 donors underwent plateletapheresis on both the CS-3000 (Fenwal) and the 2997 (IBM) blood cell separators. The same operator performed both procedures and conducted all product studies for each donor. Platelet collection efficiency was significantly greater with the 2997 (81%) than the CS-3000 (60%) (p less ...

journal_title：Transfusion

authors： Mintz PD

更新日期：1985-07-01 00:00:00

abstract：:Analysis of blood coagulation was done on samples of blood collected from ten donors undergoing combined platelet and leukapheresis using the Haemonetics Model 30 Blood Processor. Blood samples were obtained from the donors prior to, during, and following pheresis. Blood was also obtained from the blood-return line af...

journal_title：Transfusion

authors： Kisker CT,Strauss RG,Koepke JA,Maguire LC,Thompson JS

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:Photochemical treatment (PCT) with amotosalen HCl with ultraviolet A illumination inactivates pathogens and white blood cells in platelet (PLT) concentrates. STUDY DESIGN AND METHODS:In a Phase II crossover study, 32 patients with thrombocytopenia received one transfusion of PCT and/or one transfusion of un...

journal_title：Transfusion

authors： Slichter SJ,Raife TJ,Davis K,Rheinschmidt M,Buchholz DH,Corash L,Conlan MG

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The safety of fibrin tissue adhesives has been a concern since they entered wide clinical application. Most commercially available kits contain the proteolytic inhibitor, aprotinin, to stabilize the fibrin clot. A bovine protein, this substance has an allergenic potency. CASE REPORT:This case report present...

journal_title：Transfusion

authors： Beierlein W,Scheule AM,Antoniadis G,Braun C,Schosser R

更新日期：2000-03-01 00:00:00

abstract：:A technique of platelet concentrate preparation and storage is presented which permits the maximum number of viable and functional platelets to be preserved for periods of 72 hours. Although the storage conditions must be followed precisely, the method is nevertheless simple to perform and does not require specialized...

journal_title：Transfusion

authors： Slichter SJ,Harker LA

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:There is little knowledge how different hold times of hyperconcentrated platelet (PLT) suspensions (HPSs) before the addition of platelet additive solution (PAS) might affect PLT quality. We compared the in vitro quality of single-donor PLT concentrates (SDPs) with immediate or delayed PAS addition and studi...

journal_title：Transfusion

authors： Ringwald J,Tully S,Geier C,Hauck B,Weiss D,Callaert M,Eckstein R

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:A new generation of assays for the detection of human T-lymphotropic virus types I and II (HTLV-I/II) antibodies has been released. These assays incorporate HTLV-I- and HTLV-II-specific antigens, and some are based on new assay principles. Comparative evaluation data that include these new as well as previou...

journal_title：Transfusion

authors： Andersson S,Thorstensson R,Ramirez KG,Krook A,von Sydow M,Dias F,Biberfeld G

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Effective risk communication in transfusion medicine is important for health-care consumers, but understanding the numerical magnitude of risks can be difficult. The objective of this study was to determine the effect of a visual risk communication tool on the knowledge and perception of transfusion risk. S...

journal_title：Transfusion

authors： Lee DH,Mehta MD

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The quality of platelets (PLTs) stored in PLT additive solution (PAS) is dependent on the type and proportion of the used PAS. No data are available as to whether a different hold time before the addition of PAS to hyperconcentrated PLT suspensions has an impact on PLT quality. The in vitro quality between s...

journal_title：Transfusion

authors： Ringwald J,Haager B,Krex D,Zimmermann R,Strasser E,Antoon M,De Schrijver E,Eckstein R

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The characterization of microchimerism (MC) by gene amplification has been limited by few allogeneic markers, ascertainment bias, and assay analytic performance. To address this, a panel of 12 MC assays based on insertion-deletion (InDel) polymorphisms had been optimized. STUDY DESIGN AND METHODS:The InDel ...

journal_title：Transfusion

authors： Lee TH,Chafets DM,Reed W,Wen L,Yang Y,Chen J,Utter GH,Owings JT,Busch MP

更新日期：2006-11-01 00:00:00

abstract：:Adenine is an approved additive to citrate-phosphate-dextrose anticoagulant for whole blood collection and extends the storage life of red blood cells. We used in vitro methods to investigate the effects of adenine on platelet function and viability during 72 hours of storage at 22 degrees C. Although the hypotonic sh...

journal_title：Transfusion

authors： Wong SC,Rock G

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:The hemoglobin-based oxygen carrier (HBOC-201) resuscitation fluid improves outcome in hemorrhagic shock swine models with minimal coagulopathy. Herein, coagulation parameters were evaluated after resuscitation with HBOC-201 after severe bleeding and prolonged delay to definitive care. STUDY DESIGN AND METH...

journal_title：Transfusion

authors： Arnaud F,Fasipe D,Philbin N,Rice J,Flournoy WS,Ahlers S,McCarron R,Freilich D

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:A size-exclusion filter (Viresolve 180, Millipore Corp.) was tested for its ability to remove transmissible spongiform encephalopathies prion protein from an immune globulin preparation during ultrafiltration. STUDY DESIGN AND METHODS:Hamster-adapted 263K scrapie brain homogenate (SBH) was spiked into Rh0(D...

journal_title：Transfusion

authors： Van Holten RW,Autenrieth S,Boose JA,Hsieh WT,Dolan S

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization is a concern for patients who receive multiple or chronic transfusions. Alloimmunization prevalence in transfused patients with bone marrow failure syndrome (BMFS) is unknown. This study aimed to determine physician practice for RBC antigen matching, immunization rates, ...

journal_title：Transfusion

authors： Cohen D,Hartung H,Evans P,Friedman DF,Chou ST

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:It is important to compare the incidence of bacterial contamination of components collected from the peripheral blood or bone marrow (BM), as well as of components processed with or without cell selection or depletion, and to evaluate the sequelae of such contamination. STUDY DESIGN AND METHODS:Bacterial co...

journal_title：Transfusion

authors： Webb IJ,Coral FS,Andersen JW,Elias AD,Finberg RW,Nadler LM,Ritz J,Anderson KC

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Human parvovirus B19 is a common human pathogen that causes a variety of diseases with outcomes ranging from asymptomatic to severe, especially in immunocompromised patients. The B19 virus can be transmitted via blood and/or blood products and its resistance to common viral inactivation and/or removal method...

journal_title：Transfusion

authors： Ke L,He M,Li C,Liu Y,Gao L,Yao F,Li J,Bi X,Lv Y,Wang J,Hirsch ML,Li W

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Proposed testing of large plasma pools with genome amplification technology (GAT) for detection of transfusion-transmissible viruses may have unanticipated complications not associated with individual unit testing. One such potential complication, the effect of dilution resulting from pool formation, was the...

journal_title：Transfusion

authors： Kemper M,Witt D,Madsen T,Kuramoto K,Holland P

更新日期：1998-05-01 00:00:00

abstract：:The accumulation of the plasticizer di-2-ethylhexylphthalate (DEHP) in blood and blood components has been of considerable concern for some time. We have followed the accumulation of DEHP and one of its major metabolities, mono-2-ethylhexylphthalate (MEHP) during storage of whole blood, platelet-rich plasma, platelet ...

journal_title：Transfusion

authors： Rock G,Secours VE,Franklin CA,Chu I,Villeneuve DC

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is due to maternal alloimmunization against fetal platelet (PLT) antigens. Antenatal management strategies have been developed to avoid complications such as intracranial hemorrhage. The aim of this study was to set up two reliable, noninvasive fetal gen...

journal_title：Transfusion

authors： Le Toriellec E,Chenet C,Kaplan C

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization occurs at a high frequency in sickle cell anemia (SCA) despite serologic matching for Rh (C/c, E/e) and K antigens. RBC minor antigen genotyping allows for prediction of antigens and RH variants that may lead to alloimmunization. STUDY DESIGN AND METHODS:RBC antigen gen...

journal_title：Transfusion

authors： Yee MEM,Josephson CD,Winkler AM,Webb J,Luban NLC,Leong T,Stowell SR,Fasano RM

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The anti-CD20 monoclonal antibody rituximab has immune-modulatory effects similar to intravenous immunoglobulin (IVIG). We performed a systematic review and meta-analysis to determine the efficacy and safety of rituximab in autoimmune diseases that are also treated with IVIG. STUDY DESIGN AND METHODS:The mo...

journal_title：Transfusion

authors： MacIsaac J,Siddiqui R,Jamula E,Li N,Baker S,Webert KE,Evanovitch D,Heddle NM,Arnold DM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Historically, paid blood donors were found to transmit hepatitis at higher rates than volunteers. In those older studies, paid donors frequently were recruited from prisons or slum areas--a finding consistent with the belief that monetary payment in itself did not necessarily lead to the high-risk status of ...

journal_title：Transfusion

authors： Strauss RG,Ludwig GA,Smith MV,Villhauer PJ,Randels MJ,Smith-Floss A,Koerner TA

更新日期：1994-02-01 00:00:00

abstract：:First described in 1907, the crossmatch has been in a constant state of modification since that time. Major milestones in the evolution of the test include demonstration of the relative importance of red blood cell typing and of the matching test, development of rapid techniques for the test, advent of high protein, a...

journal_title：Transfusion

authors： Oberman HA

更新日期：1981-11-01 00:00:00