Red blood cell minor antigen mismatches during chronic transfusion therapy for sickle cell anemia.

abstract：:A new blood pack system for the preparation of white cell-depleted red cells was studied. The system is a modified additive-solution quadruple-unit blood pack that incorporates a cellulose-acetate fiber depth filter in-line between the AS-3 additive bag and the CP2D collection bag. Mean +/- SD white cell removal from ...

journal_title：Transfusion

authors： Davey RJ,Carmen RA,Simon TL,Nelson EJ,Leng BS,Chong C,Garcez RB,Sohmer PR

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Previously, we evaluated the Mirasol pathogen reduction technology (PRT) system on platelet (PLT) function before resuspension. We now evaluated this system in the presence of PLT additive solution (PAS). STUDY DESIGN AND METHODS:Double-dose PLTs (n = 15) were generated using a commercially available aphere...

journal_title：Transfusion

authors： Picker SM,Tauszig ME,Gathof BS

更新日期：2012-03-01 00:00:00

abstract：:Twenty-five leukaphereses were done by the Haemonetics system using citrated Dextran 75 in normal saline as anticoagulant, and were compared with a much larger series using hydroxyethyl starch (HES) with and without steroid premedication. The granulocyte and platelet yields were only minimally different between the tw...

journal_title：Transfusion

authors： Huestis DW

更新日期：1977-03-01 00:00:00

abstract：:As the number of successful marrow transplants has increased, the lack of HLA-identical sibling donors for 60 to 70 percent of transplant candidates has become a serious problem. Pilot studies established that marrow transplantation between phenotypically HLA-identical, unrelated individuals can be accomplished succes...

journal_title：Transfusion

authors： Stroncek D,Bartsch G,Perkins HA,Randall BL,Hansen JA,McCullough J

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The proposal to assess the viability capabilities of platelets (PLTs) collected, treated, or stored in a developmental system against "fresh" PLTs from the same subject poses several important methodologic issues pertaining to the timing and manner of the collecting and separating the fresh PLTs. This study ...

journal_title：Transfusion

authors： AuBuchon JP,Herschel L,Roger J

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The use of fresh red blood cells (RBCs) is recommended for critically ill patients and patients undergoing surgery, although there is no conclusive evidence that this is beneficial. In this follow-up study, the short-term and the long-term recovery of irradiated, leukoreduced RBCs transfused after either a s...

journal_title：Transfusion

authors： Luten M,Roerdinkholder-Stoelwinder B,Schaap NP,de Grip WJ,Bos HJ,Bosman GJ

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:There is little knowledge how different hold times of hyperconcentrated platelet (PLT) suspensions (HPSs) before the addition of platelet additive solution (PAS) might affect PLT quality. We compared the in vitro quality of single-donor PLT concentrates (SDPs) with immediate or delayed PAS addition and studi...

journal_title：Transfusion

authors： Ringwald J,Tully S,Geier C,Hauck B,Weiss D,Callaert M,Eckstein R

更新日期：2012-06-01 00:00:00

abstract：:KEY IDEAS Chimeric antigen receptor (CAR) T-cell therapy has the potential to improve the dismal outcome of patients diagnosed with acute myeloid leukemia (AML). A major challenge for CAR T-cell therapy of AML patients is identifying leukemia-specific target antigens. Immune escape through down-regulation of target an...

journal_title：Transfusion

authors： Sauer T,Rooney CM

更新日期：2019-04-01 00:00:00

abstract：:The selection of platelet donors, according to HLA antigens, has been computerized using a method based on the calculation of incompatibilities and risk of immunization between donors and recipients. Since the risk that an antigen present in a donor will immunize an incompatible recipient of known HLA phenotype, an in...

journal_title：Transfusion

authors： Muller JY,Cartron JP,Trillot P,Halle L,Roquin H

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:In transfusion medicine, frozen red blood cells (RBCs) are an alternative for liquid-stored RBCs. Little is known about the rheologic properties (i.e., aggregability and deformability) of thawed RBCs. In this study the rheologic properties of high-glycerol frozen RBCs and postthaw stored in saline-adenine-gl...

journal_title：Transfusion

authors： Henkelman S,Lagerberg JW,Graaff R,Rakhorst G,Van Oeveren W

更新日期：2010-11-01 00:00:00

abstract：:Iron stores were observed in 57 healthy elderly volunteers, between 63 and 77 years of age, who donated 5 units of blood over approximately 1 year. An equal number of nondonors who contributed approximately 7 mL of blood at each visit for iron status measurements only were seen at the same frequency as the donor popul...

journal_title：Transfusion

authors： Garry PJ,VanderJagt DJ,Wayne SJ,Koehler KH,Rhyne RL,Simon TL

更新日期：1991-10-01 00:00:00

abstract：:In Taiwan, the prevalence of circulating anti-HCV is 2 percent among first-time voluntary Chinese blood donors, 10 percent among donors with elevated ALT levels (greater than 45 IU/L), and higher among older men. The carrier rate for HBsAg was 18.6 percent and the frequency of positive HBV marker(s) (HBsAg, anti-HBc, ...

journal_title：Transfusion

authors： Lin-Chu M,Tsai SJ,Watanabe J,Nishioka K

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Cord blood (CB) is a widely accepted stem cell source and its clinical utilization depends, to a great extent, on its cell content. Birth-to-clamping (BTC) time of umbilical cord determines placental transfusion to the newborn, and the remaining blood that can be collected and banked. The 2017 Committee Opin...

journal_title：Transfusion

authors： Ciubotariu R,Scaradavou A,Ciubotariu I,Tarnawski M,Lloyd S,Albano M,Dobrila L,Rubinstein P,Grunebaum A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Increased zinc protoporphyrin (ZPP) levels can indicate iron deficiency and may be predictive for low hemoglobin (Hb) deferral in blood donors. Prediction models for Hb deferral in whole blood donors have already been developed. In this study, we examined if addition of ZPP to these prediction models improve...

journal_title：Transfusion

authors： Baart AM,de Kort WL,Moons KG,Atsma F,Vergouwe Y

更新日期：2013-08-01 00:00:00

abstract：:Controversy exists about the suitability of blood from autologous donors for homologous use. We compared the infectious disease test results of 426 autologous donors, designated by donor history as suitable for homologous use, to those of 86,138 volunteer donations collected over the same 5 month period. Although dono...

journal_title：Transfusion

authors： Grossman BJ,Stewart NC,Grindon AJ

更新日期：1988-05-01 00:00:00

abstract：:Transfusion medicine (TM) physicians provide medical services that benefit all patients such as providing 24-hour laboratory coverage, advising health care providers on test interpretation and selection, validating new methods, and supervising technical personnel. These services ensure delivery of accurate, reliable, ...

journal_title：Transfusion

authors： Jhang JS,Francis RO,Winkler A,Tormey C

更新日期：2017-10-01 00:00:00

abstract：:Three patients with leukemia were treated for acute leukostasis using the continuous-flow cell separator. The first patient, treated with a standard procedure sustained only a 14 per cent decrease in leukocyte count even though 50 X 10(10) leukocytes were removed. A more aggressive approach was taken with the second t...

journal_title：Transfusion

authors： Lane TA

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:Invariant natural killer T cells (iNKT cells) may suppress graft-versus-host disease (GVHD) after allogeneic transplantation. The purpose of this study was to investigate the therapeutic potential of iNKT cells from major histocompatibility complex (MHC)-mismatched donors for preventing GVHD after allogeneic...

journal_title：Transfusion

authors： Yang J,Gao L,Liu Y,Ren Y,Xie R,Fan H,Qian K

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:There is evidence that physicians lack adequate transfusion medicine knowledge. To design needs-based educational interventions to address this gap, a validated assessment tool is required. Previously published exams have not been created or validated using rigorous psychometric methods. STUDY DESIGN AND ME...

journal_title：Transfusion

authors： Haspel RL,Lin Y,Fisher P,Ali A,Parks E,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Accurate and reliable measurement of the volume of fetal D+ cells in D- women is required for adequate anti-D prophylaxis. A semiautomated flow cytometry assay based on a standardized calibration curve that was created with simulated fetomatemal hemorrhage (FMH) mixtures was developed. STUDY DESIGN AND METH...

journal_title：Transfusion

authors： Greiss MA,Armstrong-Isher SS,Perera WS,Brown PM,Urbaniak SJ

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Life-threatening situations requiring blood transfusion under extreme conditions or in remote and austere locations, such as the battlefield or in traffic accidents, would benefit from reliable blood typing practices that are easily understood by a nonscientist or nonlaboratory technician and provide quick r...

journal_title：Transfusion

authors： Clavier B,Pouget T,Sailliol A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Stored red blood cells (RBCs) undergo progressive deleterious functional, biochemical, and structural changes. The mechanisms responsible for the adverse effects of transfusing stored RBCs remain incompletely elucidated. STUDY DESIGN AND METHODS:Awake wild-type (WT) mice, WT mice fed a high-fat diet (HFD-fe...

journal_title：Transfusion

authors： Yu B,Lei C,Baron DM,Steinbicker AU,Bloch KD,Zapol WM

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Surgical patients receive platelet concentrates (PCs) for a variety of indications. However, there is limited evidence for efficacy or dosing of PCs. STUDY DESIGN AND METHODS:We performed a retrospective cohort study of surgical patients receiving isolated PC transfusion at a single academic tertiary medica...

journal_title：Transfusion

authors： Anders M,Rock P,Cartron A,Chow J,Henderson R,Martz D,Tanaka K,Mazzeffi M

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Recovery and half-life estimations were carried out to compare a high-purity factor IX concentrate with an established factor IX complex concentrate. STUDY DESIGN AND METHODS:Two high-purity factor IX concentrates, which are identical except for the presence or absence of heparin (Immuninehep-plus and Immun...

journal_title：Transfusion

authors： Poon MC,Aledort LM,Anderle K,Kunschak M,Morfini M

更新日期：1995-04-01 00:00:00

abstract：:The supernatant plasma which remains after cryoprecipitation is a useful component for transfusion therapy. However, from prior studies it was unclear how well plasma clotting factors were preserved following cryoprecipitation. Coagulation factor assays were performed on fresh plasma, supematant plasma after removal o...

journal_title：Transfusion

authors： Roth GJ,Tobias KI

更新日期：1974-03-01 00:00:00

abstract：BACKGROUND:Plasma is commonly used for vitamin K antagonist (VKA) reversal, but observational studies suggest that it is associated with transfusion-related adverse reactions (e.g., volume overload). However, this issue has not previously been addressed in a randomized controlled trial (RCT). STUDY DESIGN AND METHODS:...

journal_title：Transfusion

authors： Refaai MA,Goldstein JN,Lee ML,Durn BL,Milling TJ Jr,Sarode R

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The use of blood-saving techniques in elective surgery can produce a favorable cost-benefit ratio only when there is a reasonable likelihood that transfusion will be required. To apply a targeted blood-sparing technique in lung cancer surgery, the patient's preoperative characteristics that predict the use o...

journal_title：Transfusion

authors： Cirasino L,Barosi G,Torre M,Crespi S,Colombo P,Belloni PA

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:The overall risk of hemolytic transfusion reactions (HTRs) from plasma (minor)-incompatible platelet (PLT) transfusions and the role of a critical anti-A or anti-B titer in predicting and preventing these reactions has not been clearly established. STUDY DESIGN AND METHODS:We evaluated all apheresis PLT (AP...

journal_title：Transfusion

authors： Karafin MS,Blagg L,Tobian AA,King KE,Ness PM,Savage WJ

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Platelet-derived biologic response modifiers (BRMs) including RANTES and transforming growth factor (TGF)-beta1 accumulate in platelet components during storage because of platelet activation, and they may play a causative role in nonhemolytic febrile transfusion reactions. The majority of PCs with high unit...

journal_title：Transfusion

authors： Fujihara M,Ikebuchi K,Wakamoto S,Sekiguchi S

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Data on red blood cell (RBC) transfusion in the United States show variation in practice and overprescribing or overdosing is considered to be prevalent. Education or restrictive interventions could modify practice. STUDY DESIGN AND METHODS:RBC transfusion and mortality rates were recorded in a single insti...

journal_title：Transfusion

authors： Tavares MM,Diquattro PJ,Sweeney JD

更新日期：2014-10-01 00:00:00