Glucose-6-phosphate dehydrogenase activity decreases during storage of leukoreduced red blood cells.

abstract：BACKGROUND:Stress-enhanced platelet (PLT) storage lesions include increased glycolysis, discoid-to-sphere morphology change, and spontaneous PLT activation. It is not clear if reduction in glycolysis can alleviate storage lesion development. STUDY DESIGN AND METHODS:Apheresis PLT concentrates were exposed to 17.2 J/mL...

journal_title：Transfusion

authors： Li J,Goodrich L,Hansen E,Edrich R,Gampp D,Goodrich RP

更新日期：2005-11-01 00:00:00

abstract：:With an interval of eight weeks between collections, blood was drawn twice from 120 blood donors. At one of the donations, 0.25 ml of synthetic vasopressin, (DDAVP, 1300 micrograms/ml), was administered intranasally 60 minutes prior to collection of the blood. No drug was given at the other donation. The yield of fact...

journal_title：Transfusion

authors： Mikaelsson M,Nilsson IM,Vilhardt H,Wiechel B

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Donor white cells (WBCs) in blood transfusions are responsible for complications in recipients, including alloimmunization, graft-versus-host disease (GVHD), and virus transmission and reactivation. The recent use of sequence-specific polymerase chain reaction assays to monitor the kinetics of clearance of d...

journal_title：Transfusion

authors： Goodarzi MO,Lee TH,Pallavicini MG,Donegan EA,Busch MP

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to explore the molecular basis of the p phenotype by analysis of the recently cloned 4-alpha-galactosyltransferase gene responsible for synthesis of Pk (Gb3) antigen. STUDY DESIGN AND METHODS:Forty samples from individuals of eight different nationalities were investigated by s...

journal_title：Transfusion

authors： Hellberg A,Steffensen R,Yahalom V,Sojka BN,Heier HE,Levene C,Poole J,Olsson ML

更新日期：2003-07-01 00:00:00

abstract：:Three cases are presented in which the presence of sodium caprylate dependent albumin auto-agglutinins in the patients' sera resulted in erroneous Rh-hr phenotyping of their erythrocytes. In the initial testing, the albumin control was negative in each case. Since one of the cases was an Rh0(D) negative individual who...

journal_title：Transfusion

authors： Reid ME,Ellisor SS,Frank BA

更新日期：1975-09-01 00:00:00

abstract：:We observed complement (C) activation during intermittent flow apheresis procedures (Haemonetics model 30) in four subjects, two of whom developed adult respiratory distress syndrome (ARDS). Actual C3 conversion during apheresis was illustrated by the finding of significantly elevated C3d levels (p less than 0.05) and...

journal_title：Transfusion

authors： Boogaerts MA,Roelant C,Goossens W,Verwilghen RL

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Donor stimulation with granulocyte-colony-stimulating factor (G-CSF) has increased the number of neutrophils (PMNs) that can be collected for granulocyte transfusion therapy. Clinical utility, however, has been limited by the inability to store functional PMNs ex vivo. This study was conducted to determine w...

journal_title：Transfusion

authors： Hubel K,Rodger E,Gaviria JM,Price TH,Dale DC,Liles WC

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Ultrasound-facilitated delivery of topical anesthetics has been used to achieve effective anesthesia within 5 minutes for venipuncture and the insertion of intravenous access devices, but has never been studied for blood donation. STUDY DESIGN AND METHODS:This study was a single-center, prospective, randomi...

journal_title：Transfusion

authors： Stowell CP,Trieu MQ,Chuang H,Katz N,Quarrington C

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The clinical significance of alloimmunization to RBC antigens in sickle cell patients was analyzed by a retrospective review of the records of pediatric and adult sickle cell patients who received transfusions and who were followed over a 10-year period. STUDY DESIGN AND METHODS:Charts of pediatric and adul...

journal_title：Transfusion

authors： Aygun B,Padmanabhan S,Paley C,Chandrasekaran V

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Changes within the ABO system are regularly observed phenomena in allogeneic bone marrow transplantation (BMT) and peripheral blood progenitor cell transplantation (PBPCT). Major ABO mismatch can lead to different clinical problems including acute hemolysis after infusion of the allograft, delay of red blood...

journal_title：Transfusion

authors： Scholl S,Klink A,Mügge LO,Schilling K,Höffken K,Sayer HG

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Brucellosis is a severe zoonotic disease that is increasingly prevalent in north China. A study evaluating Brucella infection in blood donors was conducted at Kashi central blood station, Xinjiang, China. STUDY DESIGN AND METHODS:Four serologic and two molecular methods of detection of Brucella infection we...

journal_title：Transfusion

authors： Wang W,Liao Q,Wu X,Hou S,Wang Y,Wu J,Shen C,Chen S,Allain JP,Li C

更新日期：2015-03-01 00:00:00

abstract：:A technique of platelet concentrate preparation and storage is presented which permits the maximum number of viable and functional platelets to be preserved for periods of 72 hours. Although the storage conditions must be followed precisely, the method is nevertheless simple to perform and does not require specialized...

journal_title：Transfusion

authors： Slichter SJ,Harker LA

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Hemoglobin (Hb)-based oxygen (O2 ) carriers (HBOCs) are being developed as alternatives to red blood cells and blood when these products are unavailable. Clinical trials of previous HBOC generations revealed side effects, including hypertension and vasoconstriction, that were not observed in preclinical stud...

journal_title：Transfusion

authors： Muller CR,Williams AT,Munoz CJ,Eaker AM,Breton AN,Palmer AF,Cabrales P

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND:When problems with compatibility beyond ABO and D arise, currently transfusion services search their inventories and perform time-consuming serologic testing to locate antigen-negative blood. These clinically important blood group antigens can be detected reliably by red cell genotyping, which is a technolog...

journal_title：Transfusion

authors： Flegel WA,Gottschall JL,Denomme GA

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Passive immunotherapy in human immunodeficiency virus (HIV) infection is based on transfusions of plasma that is rich in HIV antibodies. STUDY DESIGN AND METHODS:To verify whether the clearance of transfused antibodies will maintain an elevated titer of specific antibodies between biweekly transfusions of p...

journal_title：Transfusion

authors： Lefrère JJ,Roudot-Thoraval F,Vittecoq D,Heshmati F,Audat F,Lerable J,Reed D,Petit JC,Burghoffer B,Morand-Joubert L

更新日期：1996-08-01 00:00:00

abstract：:Anti-Emm, an antibody to a public red cell antigen, was found in the serums of four Emm-propositi and in the serum of the Emm-brother of one of them. Three of the propositi were men, and their antibodies, as well as that of the compatible brother, were believed to be "naturally occurring." Since there are two Emm-sibl...

journal_title：Transfusion

authors： Daniels GL,Taliano V,Klein MT,McCreary J

更新日期：1987-07-01 00:00:00

abstract：:The selection of platelet donors, according to HLA antigens, has been computerized using a method based on the calculation of incompatibilities and risk of immunization between donors and recipients. Since the risk that an antigen present in a donor will immunize an incompatible recipient of known HLA phenotype, an in...

journal_title：Transfusion

authors： Muller JY,Cartron JP,Trillot P,Halle L,Roquin H

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Radiation and filtration have achieved satisfactory results in inactivation or removal of tumor cells mixed in salvage blood, but some drawbacks remain. This study evaluated the inactivation on HCT116 cells mixed in simulative salvage blood by riboflavin photochemical treatment. METHODS:HCT116 cells were ad...

journal_title：Transfusion

authors： Yu Y,Yang L,He C,Tai S,Ma C,Yang T,Wang D

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Autoimmune hemolytic anemia (AIHA) is usually classified as either warm or cold type. During the past few decades, mixed types (Mxs) have also been described in a number of cases (6%-8% of AIHA), often without serologic data to support the diagnosis. In this study, we demonstrate that the incidence of Mx AIH...

journal_title：Transfusion

authors： Mayer B,Yürek S,Kiesewetter H,Salama A

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:In August 2016, the Food and Drug Administration advised US blood centers to screen all whole blood and apheresis donations for Zika virus (ZIKV) with an individual-donor nucleic acid test (ID-NAT) or to use approved pathogen reduction technology (PRT). The cost of implementing this guidance nationally has n...

journal_title：Transfusion

authors： Ellingson KD,Sapiano MRP,Haass KA,Savinkina AA,Baker ML,Henry RA,Berger JJ,Kuehnert MJ,Basavaraju SV

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:The FUT2 gene regulates the expression of ABH antigens in body secretions and hence controls the secretor status. It is highly polymorphic. STUDY DESIGN AND METHODS:Healthy Chinese (n = 79) and Caucasian (n = 20) subjects were recruited for this study. Lewis blood group and secretor status were determined. ...

journal_title：Transfusion

authors： Yip SP,Lai SK,Wong ML

更新日期：2007-08-01 00:00:00

abstract：:Intravenous iron-dextran therapy can cause a red-brown discoloration of the plasma, simulating a hemolytic transfusion reaction. A rapid and simple test to differentiate between true hemolysis and plasma discoloration due to circulating iron-dextran complexes is described. ...

journal_title：Transfusion

authors： Simon SD,Kuriyan MA,Kim HC

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Hypoxia is a major cause of painful vaso-occlusive crisis in sickle cell disease (SCD). Simple transfusion and red blood cell (RBC) exchange are commonly used as preventive therapies whose aim is to dilute hemoglobin (Hb)S-containing RBCs (SS-RBCs) with normal RBCs (AA-RBCs) to prevent sickling. We hypothesi...

journal_title：Transfusion

authors： Bourgeaux V,Hequet O,Campion Y,Delcambre G,Chevrier AM,Rigal D,Godfrin Y

更新日期：2010-10-01 00:00:00

abstract：:After immunization with native human red cells and red cells infected with Plasmodium falciparum, mouse splenocytes were fused with a myeloma cell line to obtain hybridomas. Among the antibodies specific for blood group antigens, four antibodies (iB3C4, F12, MR432, and iB4) directed against epitopes related to the Rh ...

journal_title：Transfusion

authors： Rouger P,Edelman L

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Human natural killer (NK) cells are thought to play a role in antiviral response and tumor immune surveillance. The molecular mechanisms of down regulation of NK-cell activity observed after red blood cell (RBC) transfusion is still undefined. STUDY DESIGN AND METHODS:Both effects of blood transfusion (ex v...

journal_title：Transfusion

authors： Ghio M,Contini P,Negrini S,Mazzei C,Zocchi MR,Poggi A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Cellular blood components are irradiated to prevent graft-versus-host disease in transfusion recipients at risk for this syndrome. Because gamma radiation can result in the production of reactive oxygen species, the role of reactive oxygen species was investigated in radiation-induced red cell damage. STUDY...

journal_title：Transfusion

authors： Anand AJ,Dzik WH,Imam A,Sadrzadeh SM

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:At most US blood centers, patients may still opt to choose specific donors to give blood for their anticipated transfusion needs. However, there is little evidence of improved safety with directed donation when compared to volunteer donation. STUDY DESIGN AND METHODS:The percentage of directed donations mad...

journal_title：Transfusion

authors： Dorsey KA,Moritz ED,Steele WR,Eder AF,Stramer SL

更新日期：2013-06-01 00:00:00

abstract：:Sterility of blood products is a cardinal contributor to patient safety. Bacteriologic controls of stable products comply with strict regulations, but legislation imposes only limited constraints in the case of perishable products, such as packed red cells (RBCs) or fresh-frozen plasma (FFP). Therefore, it is essentia...

journal_title：Transfusion

authors： Guéguen M,Durand F,Delamaire D,Beauplet A,Tardivel R,Genetet B,Chalumeau H,Balme MC

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:The outcome of peripheral blood stem cell (PBSC) harvest depends on mobilization and leukapheresis. Some poor harvests might not be directly related to poor mobilizations. STUDY DESIGN AND METHODS:We retrospectively analyzed the results of 793 consecutive healthy donors who underwent PBSC donation to evalua...

journal_title：Transfusion

authors： Wang TF,Chen SH,Yang SH,Su YC,Chu SC,Li DK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Travelers returning to the United States from malaria-endemic areas are at increased risk of a potentially fatal infection from Plasmodium falciparum, which requires prompt and aggressive treatment. STUDY DESIGN AND METHODS:Described is a case of a 7-year-old boy who was infected by P. falciparum while in A...

journal_title：Transfusion

authors： Shelat SG,Lott JP,Braga MS

更新日期：2010-04-01 00:00:00