Analysis of platelet-derived extracellular vesicles in plateletpheresis concentrates: a multicenter study.

abstract：BACKGROUND:Obstetric services depend on the transfusion service (TS) to provide diagnostic testing and blood component therapy for clinical care pathways. STUDY DESIGN AND METHODS:We describe three quality improvement (QI) initiatives implemented to improve TS support of obstetric services. RESULTS:We implemented a p...

journal_title：Transfusion

authors： Goodnough LT,Daniels K,Wong AE,Viele M,Fontaine MF,Butwick AJ

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:There is evidence that physicians lack adequate transfusion medicine knowledge. To design needs-based educational interventions to address this gap, a validated assessment tool is required. Previously published exams have not been created or validated using rigorous psychometric methods. STUDY DESIGN AND ME...

journal_title：Transfusion

authors： Haspel RL,Lin Y,Fisher P,Ali A,Parks E,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:A single injection of pegfilgrastim has been shown to be equivalent to daily filgrastim in enhancing neutrophil recovery after chemotherapy, whereas the experiences with pegfilgrastim in mobilization of peripheral blood progenitor cells (PBPCs) are limited. STUDY DESIGN AND METHODS:Forty unselected patients...

journal_title：Transfusion

authors： Kroschinsky F,Hölig K,Platzbecker U,Poppe-Thiede K,Ordemann R,Blechschmidt M,Oelschlaegel U,Schaich M,Hänel M,Bornhäuser M,Ehninger G

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) infections in very-low-birthweight infants can lead to serious clinical consequences. When CMV-related symptoms occur after transfusion, CMV transmission is often attributed to the transfusion products rather than to breast milk. However, it is sometimes difficult to distinguish between...

journal_title：Transfusion

authors： Yamagishi N,Furui Y,Koshinami S,Ichijo K,Shimizu Y,Hoshi Y,Gotanda Y,Miyakawa K,Uchida S,Tadokoro K,Nagai T,Satake M

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The use of blood-saving techniques in elective surgery can produce a favorable cost-benefit ratio only when there is a reasonable likelihood that transfusion will be required. To apply a targeted blood-sparing technique in lung cancer surgery, the patient's preoperative characteristics that predict the use o...

journal_title：Transfusion

authors： Cirasino L,Barosi G,Torre M,Crespi S,Colombo P,Belloni PA

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Deterioration in quality of platelet concentrates (PCs) during storage results from the appearance of storage lesions affecting the hemostatic functions and posttransfusion survival of platelets. These lesions depend on the preparation and pathogen inactivation methods used, duration of storage, and platelet...

journal_title：Transfusion

authors： Isola H,Ravanat C,Rudwill F,Pongerard A,Haas D,Eckly A,Gachet C,Hechler B

更新日期：2021-02-01 00:00:00

abstract：:A prospective double-blind study compared a manual hexadimethrine bromide (Polybrene) antiglobulin antibody detection test (P-AHG) and crossmatch with the albumin-antiglobulin antibody detection test and saline-antiglobulin crossmatch routinely used in our laboratory. A total of 10,084 pretransfusion blood samples fro...

journal_title：Transfusion

authors： Mintz PD,Anderson G

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:RBCs modified with cyanuric chloride activated methoxy-PEG (CmPEG; 5000 Da) are less immunogenic than untreated RBCs, and their use thus may reduce the risk of alloimmunization in chronically transfused patients. STUDY DESIGN AND METHODS:To further examine the potential utility of CmPEG-RBCs, the effects of...

journal_title：Transfusion

authors： Bradley AJ,Test ST,Murad KL,Mitsuyoshi J,Scott MD

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Although P1 and Xga are known to be associated with the A4GALT and XG genes, respectively, the genetic basis of antigen expression has been elusive. Recent reports link both P1 and Xga expression with nucleotide changes in the promotor regions and with antigen-negative phenotypes due to disruption of transcr...

journal_title：Transfusion

authors： Lane WJ,Aguad M,Smeland-Wagman R,Vege S,Mah HH,Joseph A,Blout CL,Nguyen TT,Lebo MS,Sidhu M,Lomas-Francis C,Kaufman RM,Green RC,Westhoff CM,MedSeq Project.

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Platelets (PLTs) contain purinergic receptors for ATP (P2X1) and ADP (P2Y1 and P2Y12) that rapidly desensitize upon stimulation with these nucleotides. In vivo, this is antagonized by ectonucleotidases on the surface of endothelial cells and white blood cells (WBCs). The receptor desensitization of ATP- and ...

journal_title：Transfusion

authors： Cauwenberghs S,Feijge MA,Hageman G,Hoylaerts M,Akkerman JW,Curvers J,Heemskerk JW

更新日期：2006-06-01 00:00:00

abstract：:Sterility of blood products is a cardinal contributor to patient safety. Bacteriologic controls of stable products comply with strict regulations, but legislation imposes only limited constraints in the case of perishable products, such as packed red cells (RBCs) or fresh-frozen plasma (FFP). Therefore, it is essentia...

journal_title：Transfusion

authors： Guéguen M,Durand F,Delamaire D,Beauplet A,Tardivel R,Genetet B,Chalumeau H,Balme MC

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Mild cases of hemolytic disease of the newborn were being studied when it was recognized that the propositi's red cells carried a novel antigen. STUDY DESIGN AND METHODS:Serologic and genetic studies of a new low-incidence antigen, LOCR (International Society of Blood Transfusion series number 700.53), were...

journal_title：Transfusion

authors： Coghlan G,McCreary J,Underwood V,Zelinski T

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Patients with autoimmune lymphoproliferative syndrome (ALPS) have an autosomal dominant genetic defect that affects lymphocyte apoptosis and is associated with chronic nonmalignant lymphadenopathy, splenomegaly, and autoimmunity, particularly affecting RBCs, WBCs, and platelets. STUDY DESIGN AND METHODS:DAT...

journal_title：Transfusion

authors： Stroncek DF,Carter LB,Procter JL,Dale JK,Straus SE

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Posttransfusion graft-versus-host disease (PT-GVHD) is underdiagnosed and underreported. Risk factors predisposing to PT-GVHD in newborn recipients, the clinical manifestations of the disease in newborns, and its mechanism are not well characterized. STUDY DESIGN AND METHODS:A literature review identified 2...

journal_title：Transfusion

authors： Ohto H,Anderson KC

更新日期：1996-02-01 00:00:00

abstract：:KEY IDEAS Chimeric antigen receptor (CAR) T-cell therapy has the potential to improve the dismal outcome of patients diagnosed with acute myeloid leukemia (AML). A major challenge for CAR T-cell therapy of AML patients is identifying leukemia-specific target antigens. Immune escape through down-regulation of target an...

journal_title：Transfusion

authors： Sauer T,Rooney CM

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Although prior studies support the use of a hemoglobin (Hb) transfusion trigger of 7 to 8 g/dL for most hospitalized adults, there are few studies in pediatric populations. We therefore investigated transfusion practices and Hb triggers in hospitalized children. STUDY DESIGN AND METHODS:We performed a histo...

journal_title：Transfusion

authors： Klaus SA,Frank SM,Salazar JH,Cooper S,Beard L,Abdullah F,Fackler JC,Heitmiller ES,Ness PM,Resar LM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Methods that detect a child's homozygosity by examination of allelic products are insensitive for diagnosing incest because, at a given locus, a homozygous state is expected with a frequency of only 0.25 when parents are first-degree relatives. Furthermore, these methods are not specific if the population co...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA,Houtz T

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:We present an analysis of the first 2 years of hepatitis B virus (HBV) nucleic acid testing (NAT) of the Australian donor population. STUDY DESIGN AND METHODS:Between July 5, 2010, and July 4, 2012, all blood donations were screened for HBV DNA and hepatitis B surface antigen (HBsAg). Donors who tested HBsA...

journal_title：Transfusion

authors： Kiely P,Margaritis AR,Seed CR,Yang H,Australian Red Cross Blood Service NAT Study Group.

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:All published reports have described methods for virus photoinactivation which significantly alter red cell (RBC) properties during storage. In order to improve virucidal activity and reduce damage to RBCs, a series of phenothiazine derivatives were either synthesized or purified and screened for bacteriopha...

journal_title：Transfusion

authors： Wagner SJ,Skripchenko A,Robinette D,Mallory DA,Cincotta L

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the potential yield of introducing nucleic acid amplification testing (NAT) in blood donation, according to the detection threshold and the pool size. STUDY DESIGN AND METHODS:A mathematical model of early HIV-1 population dynamics in blood has been developed and is used ...

journal_title：Transfusion

authors： Le Corfec E,Le Pont F,Tuckwell HC,Rouzioux C,Costagliola D

更新日期：1999-10-01 00:00:00

abstract：:Quality control to detect inadequately deglycerolized red blood cells can be easily and inexpensively accomplished by suspending the deglycerolized cells in either recipient serum or normal saline in the same way in which the routine crossmatch is performed. In vitro hemolysis is readily and consistently apparent when...

journal_title：Transfusion

authors： Silver H,Umlas J,Kenney P,Anderson J,Pina B,Cross D

更新日期：1982-05-01 00:00:00

abstract：:Pyruvate was placed in experimental CPD-adenine (0.25 mM) blood preservative mixtures in four concentrations ranging from 40 to 320 mM. In the 320 mM pyruvate preservative, 2,3-DPG levels were elevated above normal for six weeks of whole blood storage at 4 C. The lower pyruvate concentrations maintained elevated or no...

journal_title：Transfusion

authors： Dawson RB,Hershey RT,Myers CS

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:A sample mix-up occurred in a tissue procurement laboratory in which aliquots of serum from two tissue donors were accidentally mislabeled. The clues to the apparent mixup involved discrepant Hepatitis C test results. In an attempt to resolve the apparent mix up, DNA typing was performed using serum samples ...

journal_title：Transfusion

authors： Allen RW,Pritchard JK

更新日期：2004-12-01 00:00:00

abstract：:Acute trauma with severe bleeding caused the unavoidable transfusion of Rh-positive red cells (RBCs) to a young, childless, Rh-negative woman during surgery. Of the 10 units of RBCs given, 6 were Rh positive. An alternative treatment for large-volume exposure involves the removal of some of the Rh-positive cells trans...

journal_title：Transfusion

authors： Werch J,Todd C

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:As clinical diagnosis of heparin-associated thrombocytopenia (HAT) is often difficult, confirmation by sensitive laboratory assays is desirable. STUDY DESIGN AND METHODS:The sensitivity of the heparin-induced platelet activation (HIPA) test and the platelet aggregation test (PAT) was prospectively compared ...

journal_title：Transfusion

authors： Greinacher A,Amiral J,Dummel V,Vissac A,Kiefel V,Mueller-Eckhardt C

更新日期：1994-05-01 00:00:00

abstract：:Th activation of red cells is characterized by agglutination with the peanut lectin from Arachis hypogaea and is diminished by treatment with proteolytic enzymes. The first cases of Th activation were associated with bacterial infections. More recently, a high incidence of Th activation in congenital hypoplastic anemi...

journal_title：Transfusion

authors： Wahl CM,Herman JH,Shirey RS,Kickler TS,Ness PM

更新日期：1989-09-01 00:00:00

abstract：:Bone marrow was harvested for the purpose of autologous bone marrow transplantation (ABMT) in 21 patients previously treated with chemotherapy and in complete remission from acute leukemia or non-Hodgkin's lymphoma. The volume required to obtain 2 x 10(8) nucleated cells per kg was less than 15 mL per kg in 13 patient...

journal_title：Transfusion

authors： Sonneveld P,de Leeuw CA,Schipperus M,Lindemans J,Abels J

更新日期：1990-05-01 00:00:00

abstract：:We investigated the possibility that the functional impairment in neutrophil (PMN) chemotaxis which occurs during granulocyte concentrate storage might be due to autotoxicity from the release of neutrophil granule contents during storage. Preliminary experiments confirmed that the exposure of fresh PMNs to the intrace...

journal_title：Transfusion

authors： Lane TA,Lamkin GE

更新日期：1985-03-01 00:00:00

abstract：:The present study describes the use of a new polyacrolein microsphere (acrobead) protein A column. This method enables immunomodulation by the perfusion of whole blood. The efficacy of the column and its adverse effects following perfusion of blood of patients with immune thrombocytopenic purpura (ITP) or malignancies...

journal_title：Transfusion

authors： Dvilansky A,Aharon M,Riesenfeld G,Nathan I

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:The history of the development and implementation of the Brazilian nucleic acid testing (NAT) platform to detect and discriminate among human immunodeficiency virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) infections in blood donors is described here. The results for the sensitivity, repro...

journal_title：Transfusion

authors： Rocha D,Andrade E,Godoy DT,Fontana-Maurell M,Costa E,Ribeiro M,Ferreira AGP,Brindeiro R,Tanuri A,Alvarez P

更新日期：2018-04-01 00:00:00