Abstract:
:Acute trauma with severe bleeding caused the unavoidable transfusion of Rh-positive red cells (RBCs) to a young, childless, Rh-negative woman during surgery. Of the 10 units of RBCs given, 6 were Rh positive. An alternative treatment for large-volume exposure involves the removal of some of the Rh-positive cells transfused at a time when the patient's condition could not be jeopardized by the shortage of Rh-negative RBCs. It is believed that the combination of erythrocytapheresis followed by Rh immune globulin treatment was successful, when immunoprophylaxis alone might not have been. It is strongly recommended that partial RBC exchange for the removal of the unwanted RBCs be considered in addition to Rh immune globulin treatment in cases of large-volume exposure such as the one presented.
journal_name
Transfusionjournal_title
Transfusionauthors
Werch J,Todd Cdoi
10.1046/j.1537-2995.1993.33693296819.xsubject
Has Abstractpub_date
1993-06-01 00:00:00pages
530-2issue
6eissn
0041-1132issn
1537-2995journal_volume
33pub_type
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