Semaphorin 3A alters endothelial cell immunogenicity by regulating Class II transactivator activity circuits.

abstract：:Prior studies have suggested that a high percentage of blood transfusions to hospital patients are unnecessary. If such transfusions can be reduced, more blood would be made available for those patients with legitimate blood requirements. In this study, blood transfusion of 401 nonoperated hospital patients with anemi...

journal_title：Transfusion

authors： Friedman BA

更新日期：1978-03-01 00:00:00

abstract：:A method is described which absorbs anti-Chido from serum without reducing the strength of other alloantibodies. Autologous red blood cells are coated with homologous C4 by a low-ionic-strength method and then used for the absorption. This is a practical method for removing anti-Chido from serum so that underlying all...

journal_title：Transfusion

authors： Ellisor SS,Shoemaker MM,Reid ME

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Standard plateletpheresis techniques and effects on platelet (PLT) donors were investigated to provide an informative basis for advancement of apheresis software. STUDY DESIGN AND METHODS:Three paired groups with 33 male and 22 female blood donors were prospectively investigated by analyzing blood counts of...

journal_title：Transfusion

authors： Strasser EF,Schuster M,Egler K,Bauer J,Weisbach V,Ringwald J,Zimmermann R,Zingsem J,Eckstein R

更新日期：2005-05-01 00:00:00

abstract：:Exchange transfusions using whole blood less than 24 hours old and deglycerolized red cells reconstituted with fresh-frozen plasma were performed in two premature infants for the treatment of hyperkalemia and cardiac arrhythmia. Improvement of their condition was immediate. ...

journal_title：Transfusion

authors： Lorch V,Jones FS,Hoersten IR

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Stress-enhanced platelet (PLT) storage lesions include increased glycolysis, discoid-to-sphere morphology change, and spontaneous PLT activation. It is not clear if reduction in glycolysis can alleviate storage lesion development. STUDY DESIGN AND METHODS:Apheresis PLT concentrates were exposed to 17.2 J/mL...

journal_title：Transfusion

authors： Li J,Goodrich L,Hansen E,Edrich R,Gampp D,Goodrich RP

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Blood conservation strategies have been shown to be effective in decreasing red blood cell (RBC) utilization in specific patient groups. However, few data exist describing the extent of RBC transfusion reduction or their impact on transfusion practice and mortality in a diverse inpatient population. STUDY D...

journal_title：Transfusion

authors： Roubinian NH,Escobar GJ,Liu V,Swain BE,Gardner MN,Kipnis P,Triulzi DJ,Gottschall JL,Wu Y,Carson JL,Kleinman SH,Murphy EL,NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III).

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:This study explored the effect of storing packed RBCs suspended in 200 mL of an alkaline, hypotonic, experimental additive solution (EAS 61). STUDY DESIGN AND METHODS:Packed RBC units prepared from RBCs collected from healthy donors in CPD were stored for 8 (n = 10) and 9 (n = 10) weeks under blood bank con...

journal_title：Transfusion

authors： Hess JR,Rugg N,Knapp AD,Gormas JF,Silberstein EB,Greenwalt TJ

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Babesia microti, the most frequently implicated pathogen in transfusion-transmitted babesiosis, is widely endemic in the Northeast and upper Midwestern United States. High seroprevalence in endemic areas limits antibody-based donor screening. A high-performance molecular test is needed to identify donors in ...

journal_title：Transfusion

authors： Bloch EM,Lee TH,Krause PJ,Telford SR 3rd,Montalvo L,Chafets D,Usmani-Brown S,Lepore TJ,Busch MP

更新日期：2013-10-01 00:00:00

abstract：:Current standards for the preparation of factor VIII (FVIII) concentrates from human plasma recommend separation of plasma from red cells (RBCs) within 6 hours of blood donation, thereby reducing the volume of plasma from donated whole blood available for processing to FVIII concentrate. The decay of FVIII clotting ac...

journal_title：Transfusion

authors： Hughes C,Thomas KB,Schiff P,Herrington RW,Polacsek EE,McGrath KM

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:The capability of holding whole blood (WB) units at ambient temperature, overnight, should help in platelet (PLT) concentrate preparation logistics. We summarize the results of a study conducted in the early 1990s that compared, in particular, PLT and red blood cell (RBC) in vivo viability properties followi...

journal_title：Transfusion

authors： Moroff G,AuBuchon JP,Pickard C,Whitley PH,Heaton WA,Holme S

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Surgical patients receive platelet concentrates (PCs) for a variety of indications. However, there is limited evidence for efficacy or dosing of PCs. STUDY DESIGN AND METHODS:We performed a retrospective cohort study of surgical patients receiving isolated PC transfusion at a single academic tertiary medica...

journal_title：Transfusion

authors： Anders M,Rock P,Cartron A,Chow J,Henderson R,Martz D,Tanaka K,Mazzeffi M

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that can be transmitted by transfusion. The diagnosis of chronic T. cruzi infection is generally made by detecting specific antibodies that bind to parasite antigens. The aim of this study was to assess the sensitivity and specificity of a n...

journal_title：Transfusion

authors： Chang CD,Cheng KY,Jiang LX,Salbilla VA,Haller AS,Yem AW,Bryant JD,Kirchhoff LV,Leiby DA,Schochetman G,Shah DO

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Transplant-associated thrombotic microangiopathy (TA-TMA) is a multifactorial disorder, which occurs as a result of treatment-related endothelial injury and underlying disease process after hematopoietic stem cell transplantation (HSCT). The reported incidence of TA-TMA after HSCT is 0% to 74% and has shown ...

journal_title：Transfusion

authors： Kim SS,Patel M,Yum K,Keyzner A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Though a number of studies have elegantly characterized platelet activation during storage, less attention has been paid to the initial activation caused by different collection procedures. STUDY DESIGN AND METHODS:The effects of two blood cell separators on the initial activation of platelets were measured...

journal_title：Transfusion

authors： Stohlawetz P,Hergovich N,Stiegler G,Eichler HG,Höcker P,Kapiotis S,Jilma B

更新日期：1998-01-01 00:00:00

abstract：:Fatal postoperative erythroderma (POE) developed in a 52-year-old woman with gallstones who underwent elective cholecystectomy. During surgery, she was transfused with 3 units of unirradiated packed red cells stored in the liquid state for at least 4 days after collection. The POE is believed to have been the result o...

journal_title：Transfusion

authors： Otsuka S,Kunieda K,Hirose M,Takeuchi H,Mizutani Y,Nagaya M,Sato G,Kasuya S,Matsutomo K,Noma A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Nucleic acid testing (NAT) for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) was introduced for blood donation screening in the United States in 1999. This study analyzes temporal trends of these two infections since NAT introduction. STUDY DESIGN AND METHODS:Donation data from 1999 to 2008...

journal_title：Transfusion

authors： Zou S,Dorsey KA,Notari EP,Foster GA,Krysztof DE,Musavi F,Dodd RY,Stramer SL

更新日期：2010-07-01 00:00:00

abstract：:Immune-deficient patients depend on the antibodies in pooled human immunoglobulin G (IgG) preparations to remain free from serious infections. The potency of IgG preparations is therefore an ongoing concern. The use of pooled IgG to prevent infection is based on the concept that healthy adults have recovered from infe...

journal_title：Transfusion

authors： Berger M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) is an uncommon but serious transfusion reaction. Studies have shown that the transfusion of HLA and HNA antibodies in donor plasma can lead to TRALI. Female donors are more likely to have such antibodies due to alloantigen exposure during pregnancy. Many blood su...

journal_title：Transfusion

authors： Arinsburg SA,Skerrett DL,Karp JK,Ness PM,Jhang J,Padmanabhan A,Gibble J,Schwartz J,King KE,Cushing MM

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:There has been increased worldwide emphasis on the many benefits of human immunodeficiency virus (HIV) serostatus awareness for both infection prevention and improved treatment outcomes. Previous studies indicate that donors may use blood donation to be tested; the objectives of this analysis were to assess,...

journal_title：Transfusion

authors： Bruhn R,Moreno E,Sabino EC,Ferreira NA,Carneiro-Proietti AB,Lopes ME,Sampaio D,Loureiro P,Custer B,Goncalez TT,National Heart, Lung and Blood Institute Retrovirus Epidemiology Donor Study-II (REDS-II) International Component.

更新日期：2016-11-01 00:00:00

abstract：:The two-stage method of Pool and Robinson was used in determining plasma Factor VIII activity following contact with four commercially available plastic blood and pooling bag films. Employing a two-arm double plasmapheresis technique, it was shown that Factor VIII activity in whole blood initially drawn into BB-69 and...

journal_title：Transfusion

authors： Mishler JM,Nicora RW,Hamilton JE,Caster G,Kasper CK

更新日期：1975-07-01 00:00:00

abstract：:Donation willingness is generally high but registering with donor centers lags behind. We need to understand why and when during the life course which groups of individuals are motivated to donate. With this knowledge, we can design targeted recruitment and retention strategies and improve evidence-based donor managem...

journal_title：Transfusion

authors： Piersma TW,Merz EM

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Immune thrombocytopenic purpura and secondary thrombocytopenia patients treated with Rh(o)(D) immune globulin intravenous (human; anti-D IGIV) have experienced acute hemolysis, which is inconsistent with the typical presentation of extravascular hemolysis -- the presumed mechanism of action of anti-D IGIV. A...

journal_title：Transfusion

authors： Gaines AR,Lee-Stroka H,Byrne K,Scott DE,Uhl L,Lazarus E,Stroncek DF

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The introduction of prestorage white cell (WBC) reduction in random-donor platelet concentrates in Canada has increased the occurrence of particulate material in PCs. The effects of filtration on platelet activation state and the activation of plasma enzyme systems were assessed. STUDY DESIGN AND METHODS:Pa...

journal_title：Transfusion

authors： Devine DV,Bradley AJ,Maurer E,Levin E,Chahal S,Serrano K,Gyongyossy-Issa MI

更新日期：1999-07-01 00:00:00

abstract：:A female patient developed serious hemolysis in association with the injection of a radiographic contrast medium (RCM). Serologic investigation of her serum suggested complement-mediated hemolysis, induced by an RCM-dependent IgM antibody in her serum. The antibody was of high titer and low avidity. The antibody showe...

journal_title：Transfusion

authors： Nordhagen R,Vik H,Wolthuis K,Bøhn HP,Urdahl P,Michaelsen TE

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Successful hematopoietic stem cell transplantation using stored umbilical cord blood (CB) largely depends on cell dose and quality of CB units. The aim of this study was to assess the degree of early apoptosis, in addition to cell viability and hematopoietic potential, in umbilical CB units after storage. S...

journal_title：Transfusion

authors： Kim KM,Huh JY,Hong SS,Kang MS

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:The residual blood left in the placenta, previously considered a biologic waste, contains sufficient hematopoietic stem and progenitor cells to consistently engraft at least a small recipient. Over the past several years, more than 500 HLA-matched, related and unrelated, allogeneic cord blood transplants hav...

journal_title：Transfusion

authors： Reems JA,Fujita D,Tyler T,Moldwin R,Smith SD

更新日期：1999-04-01 00:00:00

abstract：:Sera from three unrelated persons whose red cells (RBC) had the common Scianna phenotype (Sc:1,-2) contained IgG alloantibodies directed against high-frequency RBC antigens. In each case, sera or eluates or both failed to react only with Scianna null (Sc:-1,-2) cells, although an eluate from one person was compatible ...

journal_title：Transfusion

authors： Devine P,Dawson FE,Motschman TL,Skradski KJ,Orsini L,Moulds JJ,Taswell HF

更新日期：1988-07-01 00:00:00

abstract：:This review considers the various methods currently in use, or under investigation, for the storage of platelets intended for use in the treatment of active hemorrhage. The current standard practice of storing platelets at room temperature (RT) (20°C-24°C) optimizes circulating time, but at the expense of hemostatic f...

journal_title：Transfusion

authors： Milford EM,Reade MC

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Recently, a more accurate and reliable screening test has been investigated for noninvasive prenatal fetal RHD genotyping from D- women. The objective of this study was to perform the new method of noninvasive fetal RHD genotyping with maternal plasma from D- women by use of capillary electrophoresis. STUDY...

journal_title：Transfusion

authors： Kimura M,Sato C,Hara M,Ishihara O,Ikebuchi K

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Our blood bank is part of a large academic institution with an active sickle cell anemia program. We provide sickle patients with blood phenotypically matched for C/c, E/e, and K antigens. Since licensed reagents are available for phenotyping C/c, E/e, and K on an automated blood analyzer, we decided to eval...

journal_title：Transfusion

authors： Le N,Harach ME,Kay JK,Brown RP,Everetts JN,Herman JH

更新日期：2014-02-01 00:00:00