Evaluation and comparison of coagulation factor activity in fresh-frozen plasma and 24-hour plasma at thaw and after 120 hours of 1 to 6°C storage.

Abstract:

BACKGROUND:Current transfusion-related acute lung injury reduction strategies include avoiding transfusion of plasma products collected from female donors or female donors that have been pregnant to reduce transfusion of plasma-containing HLA antibodies. Such a policy considerably decreases the number of donors available for generation of fresh-frozen plasma (FFP). To increase the supply of FFP, substitution of 24-hour plasma (FP24) and thawed plasma (TP) derived from either FFP or FP24 may be viable substitutes. To justify such a policy the coagulation factor content of FFP, FP24, and TP derived from both product types was assessed. STUDY DESIGN AND METHODS:Coagulation factor (F)II, FV, FVII, FVIII, F IX, and FX; protein C (PC) and protein S (PS); von Willebrand factor antigen and ristocetin cofactor; fibrinogen; and antithrombin activities were analyzed in nonpaired FFP and FP24 at the time of product thaw and again after 120 hours of 1 to 6°C storage. RESULTS:At thaw, mean FVIII and PC activities were lower in FP24 than FFP. Mean PC and PS activities were lower in FP24- than FFP-derived 120-hour-old TP. No other differences in mean activity reached significance. Activity levels were generally lower in TP; FVIII, FV, and FVII showed the largest changes. However, prestorage leukoreduction appears to improve the stability of FV. CONCLUSION:FFP, FP24, and the derived TP all contain adequate coagulation factor activities to maintain hemostatic activity. As FFP becomes less available, increased use of FP24 and TP are viable alternatives for most clinical situations.

journal_name

Transfusion

journal_title

Transfusion

authors

Scott E,Puca K,Heraly J,Gottschall J,Friedman K

doi

10.1111/j.1537-2995.2009.02198.x

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

1584-91

issue

8

eissn

0041-1132

issn

1537-2995

pii

TRF02198

journal_volume

49

pub_type

杂志文章
  • Single hospital experience of TRALI.

    abstract:BACKGROUND:TRALI is a serious adverse effect of blood transfusion. There is evidence that the condition is underrecognized and underreported. STUDY DESIGN AND METHODS:This study was an observational study carried out in a single hospital. RESULTS:Eleven cases of TRALI were recognized over 12 years. In 10 cases the im...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00466.x

    authors: Wallis JP,Lubenko A,Wells AW,Chapman CE

    更新日期:2003-08-01 00:00:00

  • Semiautomated data analysis of flow cytometric estimation of fetomaternal hemorrhage in D- women.

    abstract:BACKGROUND:Accurate and reliable measurement of the volume of fetal D+ cells in D- women is required for adequate anti-D prophylaxis. A semiautomated flow cytometry assay based on a standardized calibration curve that was created with simulated fetomatemal hemorrhage (FMH) mixtures was developed. STUDY DESIGN AND METH...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00159.x

    authors: Greiss MA,Armstrong-Isher SS,Perera WS,Brown PM,Urbaniak SJ

    更新日期:2002-08-01 00:00:00

  • Assessing transfusion competency in junior doctors: a retrospective cohort study.

    abstract:BACKGROUND:There is scope to further improve the safety of transfusion practice within the United Kingdom. This study aims to identify the current role of junior doctors in the transfusion process and to assess their competency to appropriately prescribe blood and blood products to patients. STUDY DESIGN AND METHODS:T...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12274

    authors: Graham J,Grant-Casey J,Alston R,Baker P,Pendry K

    更新日期:2014-01-01 00:00:00

  • Reliability of bedside ABO testing before transfusion.

    abstract:BACKGROUND:Previous studies of bedside transfusion compatibility tests have shown high rates of erroneous transfusion decision, due to defective techniques and poor user performance. An experimental study was conducted to evaluate the error rate obtained with a new ready-to-use device (Vu-Test, Medigis), in comparison ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00219.x

    authors: Migeot V,Ingrand I,Salmi LR,Ingrand P

    更新日期:2002-10-01 00:00:00

  • Red blood cell product utilization in patients undergoing allogeneic stem cell transplantation.

    abstract:BACKGROUND:The risk of transfusion reactions (TR) and the cost of blood has led to efforts to reduce blood use. We changed our practice to transfuse just one instead of two units of red blood cells (RBC) when hemoglobin ≤8 g/dL due to patient blood management (PBM) recommendations. METHODS AND MATERIALS:We compared RB...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15285

    authors: Gastecki K,Shanley R,Welbig J,Cohn C,Brunstein CG

    更新日期:2019-07-01 00:00:00

  • Immunologic changes after transfusion of autologous or allogeneic buffy coat-poor versus WBC-reduced blood transfusions in patients undergoing arthroplasty. II. Activation of T cells, macrophages, and cell-mediated lympholysis.

    abstract:BACKGROUND:To estimate the impact of RBC preparations on the status of postoperative immune activation, the soluble cytokine receptors of TNFalpha (sTNF-R) and IL-2 (sIL-2R), as well as neopterin and cell-mediated lympholysis (CML), were measured. STUDY DESIGN AND METHODS:Patients undergoing strictly standardized anes...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1537-2995.2000.40070821.x

    authors: Innerhofer P,Tilz G,Fuchs D,Luz G,Hobisch-Hagen P,Schobersberger W,Nussbaumer W,Lochs A,Irschick E

    更新日期:2000-07-01 00:00:00

  • Increasing the economic efficacy of peripheral blood progenitor cell collections by monitoring peripheral blood CD34+ concentrations.

    abstract:BACKGROUND:After mobilization, the collection of peripheral blood progenitor cells (PBPCs) can either be started a fixed number of days after having passed the white blood cell nadir (fixed-day scheme) or be based on monitoring of CD34+ cells. This study was conducted to compare both approaches and to assess possible f...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02466.x

    authors: Gutensohn K,Magens MM,Kuehnl P,Zeller W

    更新日期:2010-03-01 00:00:00

  • Dimethyl sulfoxide: effects on function of fresh platelets and on the viability of platelets in storage.

    abstract::Dimethyl sulfoxide (DMSO) is used as a cryoprotective agent when platelets are frozen. We examined the effect of DMSO (0.1 to 10%) on platelet aggregation, release, and prostaglandin synthesis (as indicated by malondialdehyde formation) in response to thrombin, collagen, arachidonic acid and calcium ionophore. Inhibit...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1983.23283172844.x

    authors: Fratantoni JC,Poindexter BJ

    更新日期:1983-03-01 00:00:00

  • A correlation between growth rate, apoptosis, and tumor necrosis factor-α in umbilical cord blood cells infected with two strains of Mycobacterium tuberculosis.

    abstract:BACKGROUND:Using umbilical cord blood (UCB) cells, it was demonstrated that three virulent isolates, two highly transmissible clinical isolates and the virulent laboratory strain, demonstrated rapid growth in the UCB cells, which was significantly faster than the growth rate observed for a unique isolate. There was als...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02187.x

    authors: Theus JW,Justus RS,Theus SA

    更新日期:2009-08-01 00:00:00

  • Spleen enlargement in healthy donors during G-CSF mobilization of PBPCs.

    abstract:BACKGROUND:Recombinant human G-CSF is widely used to mobilize PBPCs in healthy donors for allogeneic transplantation. There have been concerns about donor safety because of splenic ruptures during G-CSF application. To address this problem, changes in splenic size in 91 healthy donors during G-CSF mobilization of allog...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41020184.x

    authors: Platzbecker U,Prange-Krex G,Bornhäuser M,Koch R,Soucek S,Aikele P,Haack A,Haag C,Schuler U,Berndt A,Rutt C,Ehninger G,Hölig K

    更新日期:2001-02-01 00:00:00

  • Cell quality of apheresis-derived platelets treated with riboflavin-ultraviolet light after resuspension in platelet additive solution.

    abstract:BACKGROUND:Previously, we evaluated the Mirasol pathogen reduction technology (PRT) system on platelet (PLT) function before resuspension. We now evaluated this system in the presence of PLT additive solution (PAS). STUDY DESIGN AND METHODS:Double-dose PLTs (n = 15) were generated using a commercially available aphere...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03323.x

    authors: Picker SM,Tauszig ME,Gathof BS

    更新日期:2012-03-01 00:00:00

  • The effect of hydroxyethyl starch on in vitro platelet and granulocyte function.

    abstract::The effect of hydroxyethyl starch (HES) on granulocyte and platelet functions was assessed. No alteration of granulocyte viability, morphology, phagocytic ability, or bactericidal capacity was detected after incubation with 6 per cent HES at 25 C for two hours. Platelet morphology, size distribution, aggregation, nucl...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1975.15576082223.x

    authors: Schiffer CA,Aisner J,Schmukler M,Whitaker CL,Wolff JH

    更新日期:1975-09-01 00:00:00

  • A prospective study of blood donations in healthy elderly persons.

    abstract::Iron stores were observed in 57 healthy elderly volunteers, between 63 and 77 years of age, who donated 5 units of blood over approximately 1 year. An equal number of nondonors who contributed approximately 7 mL of blood at each visit for iron status measurements only were seen at the same frequency as the donor popul...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1991.31892023491.x

    authors: Garry PJ,VanderJagt DJ,Wayne SJ,Koehler KH,Rhyne RL,Simon TL

    更新日期:1991-10-01 00:00:00

  • Factor VIII concentrate prepared from blood donors stimulated by intranasal administration of a vasopressin analogue.

    abstract::With an interval of eight weeks between collections, blood was drawn twice from 120 blood donors. At one of the donations, 0.25 ml of synthetic vasopressin, (DDAVP, 1300 micrograms/ml), was administered intranasally 60 minutes prior to collection of the blood. No drug was given at the other donation. The yield of fact...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22382224947.x

    authors: Mikaelsson M,Nilsson IM,Vilhardt H,Wiechel B

    更新日期:1982-05-01 00:00:00

  • Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation.

    abstract:BACKGROUND:Almost 2 percent of murine blood red blood cells (RBCs) are destroyed each day and are replaced by fresh RBCs generated through the process of erythropoiesis. RBCs to be destroyed are phagocytosed by macrophages in the reticuloendothelial system, especially in the spleen. CD47 molecules on RBCs may regulate ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01348.x

    authors: Khandelwal S,van Rooijen N,Saxena RK

    更新日期:2007-09-01 00:00:00

  • Granulocyte collections: comparison of two apheresis systems.

    abstract:BACKGROUND:Donor granulocyte concentrates are routinely administered to patients with granulocyte function defects or transient neutropenia and (risk of) bacterial or fungal exacerbations, despite lack of definitive clinical proof for patient-relevant outcome improvement. Granulocytes are collected by apheresis from he...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12197

    authors: Thorausch K,Schulz M,Bialleck H,Luxembourg B,Seifried E,Bonig H

    更新日期:2013-12-01 00:00:00

  • Ranking the effectiveness of autologous blood conservation measures through validated modeling of independent clinical data.

    abstract:BACKGROUND:Future supply with allogeneic blood transfusions faces several crucial challenges that warrant thorough (re-)evaluation of existing alternatives. Meta-analyses have indicated a significant potential for autologous blood conservation (ABC) measures to reduce the need for allogeneic blood transfusions. The qua...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12233

    authors: Singbartl G,Held AL,Singbartl K

    更新日期:2013-12-01 00:00:00

  • Etoricoxib-induced immune hemolytic anemia: first case presenting acute kidney failure.

    abstract:BACKGROUND:Etoricoxib is a selective inhibitor of cyclooxygenase 2 used mainly to treat osteoarticular pain. Here, we report the case of a patient who developed acute kidney failure and immune hemolytic anemia after the use of etoricoxib. STUDY DESIGN AND METHODS:An 83-year-old female patient developed immune hemolyti...

    journal_title:Transfusion

    pub_type:

    doi:10.1111/trf.15226

    authors: Burgos Pratx L,Santoro D,Coca Mogro B,Valiente VL,Camino P,Scordo W,Salamone H

    更新日期:2019-05-01 00:00:00

  • The effect of adenine on platelet storage.

    abstract::Adenine is an approved additive to citrate-phosphate-dextrose anticoagulant for whole blood collection and extends the storage life of red blood cells. We used in vitro methods to investigate the effects of adenine on platelet function and viability during 72 hours of storage at 22 degrees C. Although the hypotonic sh...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22482251208.x

    authors: Wong SC,Rock G

    更新日期:1982-07-01 00:00:00

  • Current challenges for CAR T-cell therapy of acute myeloid leukemia.

    abstract::KEY IDEAS Chimeric antigen receptor (CAR) T-cell therapy has the potential to improve the dismal outcome of patients diagnosed with acute myeloid leukemia (AML). A major challenge for CAR T-cell therapy of AML patients is identifying leukemia-specific target antigens. Immune escape through down-regulation of target an...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.15199

    authors: Sauer T,Rooney CM

    更新日期:2019-04-01 00:00:00

  • Establishment of an unrelated umbilical cord blood bank qualification program: ensuring quality while meeting Food and Drug Administration vendor qualification requirements.

    abstract:BACKGROUND:Qualification of a cord blood bank (CBB) is a complex process that includes evaluation of multiple aspects of donor screening and testing, processing, accreditation and approval by professional cell therapy groups, and results of received cord blood units. The University of Minnesota Medical Center Cell Ther...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12085

    authors: Rabe F,Kadidlo D,Van Orsow L,McKenna D

    更新日期:2013-10-01 00:00:00

  • Impact of cytomegalovirus (CMV) antibody reflex testing in the transfusion service on management of CMV-seronegative blood inventory.

    abstract:BACKGROUND:Our goal is to minimize unnecessary cytomegalovirus (CMV)-seronegative blood transfusion to preserve the CMV-seronegative blood inventory for patients who are identified as CMV seronegative. STUDY DESIGN AND METHODS:We implemented a CMV antibody reflex testing protocol for patients who require CMV-compatibl...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02643.x

    authors: Fontaine MJ,Jurado C,Miller E,Viele M,Goodnough LT

    更新日期:2010-08-01 00:00:00

  • Comparison of a manual hexadimethrine bromide-antiglobulin test with saline- and albumin-antiglobulin tests for pretransfusion testing.

    abstract::A prospective double-blind study compared a manual hexadimethrine bromide (Polybrene) antiglobulin antibody detection test (P-AHG) and crossmatch with the albumin-antiglobulin antibody detection test and saline-antiglobulin crossmatch routinely used in our laboratory. A total of 10,084 pretransfusion blood samples fro...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27287150183.x

    authors: Mintz PD,Anderson G

    更新日期:1987-03-01 00:00:00

  • Economic impact on US Medicare of a new diagnosis of myelodysplastic syndromes and the incremental costs associated with blood transfusion need.

    abstract:BACKGROUND:Recent retrospective studies suggest myelodysplastic syndromes (MDSs) are more common than previously recognized and patients who develop transfusional dependence may be at risk for increased comorbid complications. STUDY DESIGN AND METHODS:A retrospective review was undertaken of Medicare claims focusing o...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03626.x

    authors: Goldberg SL,Chen E,Sasane M,Paley C,Guo A,Laouri M

    更新日期:2012-10-01 00:00:00

  • Prevalence and infectivity of hepatitis G virus and its strain variant, the GB agent, in volunteer blood donors in Taiwan.

    abstract:BACKGROUND:The prevalence of hepatitis G virus (HGV) and its strain variant, the GB agent (GBV-C) is high in non-virus-inactivated plasma products, but, persistent infection in recipients is relatively low. STUDY DESIGN AND METHODS:Stored samples from transfusion donors and recipients in a prospective study of posttra...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1998.38398222874.x

    authors: Wang JT,Chen PJ,Liu DP,Sheu JC,Wang TH,Chen DS

    更新日期:1998-03-01 00:00:00

  • Clinical effects of reverting from leukoreduced to nonleukoreduced blood in cardiac surgery.

    abstract:BACKGROUND:A reduction in postoperative length of stay (PLOS) was recently demonstrated with the use of leukoreduced (LR) blood in cardiac surgery patients compared to a historical cohort who received non-LR blood. Follow-up data are now presented in a similar population after a 12-month period in which LR blood was no...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2006.00733.x

    authors: Fung MK,Moore K,Ridenour M,Mook W,Triulzi DJ

    更新日期:2006-03-01 00:00:00

  • Intraoperative cell salvage in obstetrics: is it a real therapeutic option?

    abstract::Obstetric hemorrhage is a leading cause of maternal and perinatal mortality worldwide. Intraoperative blood salvage is common practice in many surgical specialties but its safety in obstetrics is questioned for concerns on the risks of contamination of recovered blood with amniotic fluid (AF) and of maternal-fetal all...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2011.03116.x

    authors: Liumbruno GM,Liumbruno C,Rafanelli D

    更新日期:2011-10-01 00:00:00

  • Estimated risk of Chikungunya viremic blood donation during an epidemic on Reunion Island in the Indian Ocean, 2005 to 2007.

    abstract:BACKGROUND:Between 2005 and 2007, Chikungunya virus (CHIKV) caused a massive epidemic on Reunion Island with a major peak in the number of cases in February 2006. Blood donation was interrupted on the island in January 2006. STUDY DESIGN AND METHODS:Estimates of the mean risk of viremic blood donation on Reunion Islan...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2008.01646.x

    authors: Brouard C,Bernillon P,Quatresous I,Pillonel J,Assal A,De Valk H,Desenclos JC,workgroup \Quantitative Estimation of the Risk of Blood Donation Contamination by Infectious Agents\.

    更新日期:2008-07-01 00:00:00

  • Donor and nondonor motivations.

    abstract::In an attempt to gain insight into the motivations of blood donors and nondonors, two paper and pencil questionnaires were developed and mailed to approximately 7,000 individuals. In response, 1,429 nondonors and 200 donors completed and returned usable questionnaires. Among donors, awareness of the need for blood, al...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1976.16276155116.x

    authors: Leibrecht BC,Hogan JM,Luz GA,Tobias KI

    更新日期:1976-03-01 00:00:00

  • A 'new' high frequency antigen Era.

    abstract::Three examples of an antibody defining a 'new' high frequency red blood cell antigen, Era, are described. Family studies show Era to be inherited, but the mode of inheritance may not be straightforward. ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22382224938.x

    authors: Daniels GL,Judd WJ,Moore BP,Neitzer G,Ouellet P,Plantos M,Verrette S

    更新日期:1982-05-01 00:00:00