The effect of hydroxyethyl starch on in vitro platelet and granulocyte function.

Abstract:

:The effect of hydroxyethyl starch (HES) on granulocyte and platelet functions was assessed. No alteration of granulocyte viability, morphology, phagocytic ability, or bactericidal capacity was detected after incubation with 6 per cent HES at 25 C for two hours. Platelet morphology, size distribution, aggregation, nucleotide and serotonin release, and platelet factor-3 availability were also unchanged after exposure to HES. It is concluded that HES has no adverse effect on cell function and appears to be a suitable adjuvant agent for blood cell component collection.

journal_name

Transfusion

journal_title

Transfusion

authors

Schiffer CA,Aisner J,Schmukler M,Whitaker CL,Wolff JH

doi

10.1046/j.1537-2995.1975.15576082223.x

subject

Has Abstract

pub_date

1975-09-01 00:00:00

pages

473-5

issue

5

eissn

0041-1132

issn

1537-2995

journal_volume

15

pub_type

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