A statistical model for estimating donor postdonation platelet counts after plateletpheresis.

Abstract:

BACKGROUND:To avoid the need, in serial apheresis donors, either to delay plateletpheresis until a predonation platelet count is completed or to obtain a postdonation count after each procedure, a statistical model has been developed to predict the postdonation platelet count from the donor predonation platelet count, weight, and hematocrit. STUDY DESIGN AND METHODS:Predonation and postdonation platelet counts were measured in two groups of approximately 100 consecutive donors (Group A to test the model and Group B to validate it), and the postdonation counts were calculated with the model. Using stepwise multiple linear regression from donor data, estimated postdonation platelet counts were found to be comparable to the postdonation platelet counts actually measured. RESULTS:Estimated postdonation platelet counts x 10(9) per L (mean +/- SD) for each group, respectively, were Group A, 195 +/- 35, versus actual platelet counts of 195 +/- 39 (p = 0.43), and Group B, 183 +/- 36, versus actual platelet counts of 189 +/- 34 (p = 0.14). Sensitivity and specificity, respectively, were Group A, 57 and 99 percent and Group B, 62 and 99 percent. CONCLUSION:For most serial apheresis donors, application of this predictor model should preclude the need to obtain an extra postdonation platelet count.

journal_name

Transfusion

journal_title

Transfusion

authors

Cabezudo I,Winegarden DK,Randels MJ,Strauss RG

doi

10.1046/j.1537-2995.1994.34194098605.x

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

54-7

issue

1

eissn

0041-1132

issn

1537-2995

journal_volume

34

pub_type

杂志文章
  • Comparison of a manual hexadimethrine bromide-antiglobulin test with saline- and albumin-antiglobulin tests for pretransfusion testing.

    abstract::A prospective double-blind study compared a manual hexadimethrine bromide (Polybrene) antiglobulin antibody detection test (P-AHG) and crossmatch with the albumin-antiglobulin antibody detection test and saline-antiglobulin crossmatch routinely used in our laboratory. A total of 10,084 pretransfusion blood samples fro...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27287150183.x

    authors: Mintz PD,Anderson G

    更新日期:1987-03-01 00:00:00

  • Evaluation of two instruments for noninvasive platelet concentrate quality assessment.

    abstract::The Platelet Monitoring System (PMS) and the Non-invasive Assessment of Platelet Shape and Concentration (NAPSAC) instruments which relate light scattering characteristics of platelet concentrates (PC) to platelet concentration and shape, were evaluated to determine their accuracy in assessing platelet quality during ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1989.29389162737.x

    authors: George V,Holme S,Moroff G

    更新日期:1989-03-01 00:00:00

  • Metabolic phenotypes of standard and cold-stored platelets.

    abstract:BACKGROUND:Conventional platelet (PLT) storage at room temperature under continuous agitation results in a limited shelf life (5 days) and an increased risk of bacterial contamination. However, both of these aspects can be ameliorated by cold storage. Preliminary work has suggested that PLTs can be cold stored for up t...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15651

    authors: D'Alessandro A,Thomas KA,Stefanoni D,Gamboni F,Shea SM,Reisz JA,Spinella PC

    更新日期:2020-06-01 00:00:00

  • Metabolic impact of red blood cell exchange with rejuvenated red blood cells in sickle cell patients.

    abstract:BACKGROUND:Red blood cell exchange (RCE) transfusions are a mainstay in the treatment of sickle cell anemia (SCA), and allow a temporary restoration of physiological parameters with respect to erythrocyte oxygen carrying capacity and systems metabolism. Recently, we noted that 1) RCE significantly impacts recipients' m...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15467

    authors: Gehrke S,Shah N,Gamboni F,Kamyszek R,Srinivasan AJ,Gray A,Landrigan M,Welsby I,D'Alessandro A

    更新日期:2019-10-01 00:00:00

  • Poor harvest of peripheral blood stem cell in donors with microcytic red blood cells.

    abstract:BACKGROUND:The outcome of peripheral blood stem cell (PBSC) harvest depends on mobilization and leukapheresis. Some poor harvests might not be directly related to poor mobilizations. STUDY DESIGN AND METHODS:We retrospectively analyzed the results of 793 consecutive healthy donors who underwent PBSC donation to evalua...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03751.x

    authors: Wang TF,Chen SH,Yang SH,Su YC,Chu SC,Li DK

    更新日期:2013-01-01 00:00:00

  • Transfusing methylene blue-photoinactivated plasma instead of FFP is associated with an increased demand for plasma and cryoprecipitate.

    abstract:BACKGROUND:Photodynamic virus inactivation of plasma with methylene blue significantly decreases the recovery of fibrinogen and coagulation factors V and VIII. Because an adequate supply of fibrinogen is essential for the therapeutic efficacy of transfused plasma in many clinical settings, it was plausible that transfu...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41121548.x

    authors: Atance R,Pereira A,Ramírez B

    更新日期:2001-12-01 00:00:00

  • Preparation of white cell-depleted red cells for 42-day storage using an integral in-line filter.

    abstract::A new blood pack system for the preparation of white cell-depleted red cells was studied. The system is a modified additive-solution quadruple-unit blood pack that incorporates a cellulose-acetate fiber depth filter in-line between the AS-3 additive bag and the CP2D collection bag. Mean +/- SD white cell removal from ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1989.29689318446.x

    authors: Davey RJ,Carmen RA,Simon TL,Nelson EJ,Leng BS,Chong C,Garcez RB,Sohmer PR

    更新日期:1989-07-01 00:00:00

  • Incidence of breakage of human RBCs frozen with 40-percent wt/vol glycerol using two different methods for storage at -80 degrees C.

    abstract:BACKGROUND:We reported previously that the incidence of breakage was 34.2 percent when human RBCs were frozen with 40-percent wt/vol glycerol in polyolefin plastic bags stored in aluminum containers at -80 degrees C and subjected to transportation. When human RBCs were frozen with 40-percent wt/vol glycerol at -80 degr...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2003.00317.x

    authors: Valeri CR,Lane JP,Srey R,Ragno G

    更新日期:2003-03-01 00:00:00

  • Evaluation of an experimental filter designed for improving the quality of red blood cells (RBCs) during storage by simultaneously removing white blood cells and immunomodulators and improving RBC viscoelasticity and Band 3 proteins.

    abstract:BACKGROUND:Storage age of red blood cells (RBCs) has been reported to be associated with increased mortality and morbidity. During storage, RBCs undergo changes in biochemical and functional properties. Stored RBCs may also contain white blood cells (WBCs), activated platelets (PLTs), cytokines, immunoglobulin, and oth...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12330

    authors: Sowemimo-Coker SO

    更新日期:2014-03-01 00:00:00

  • A national mapping assessment of blood collection and transfusion service facilities in Afghanistan.

    abstract:BACKGROUND:The purpose of this study was to assess functionality and resources of facilities providing blood collection and transfusion services in Afghanistan. STUDY DESIGN AND METHODS:This national cross-sectional assessment included facilities collecting or transfusing blood identified through official data sources...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03674.x

    authors: Mansoor GF,Rahmani AM,Kakar MA,Hashimy P,Abrahimi P,Scott PT,Peel SA,Rentas FJ,Todd CS

    更新日期:2013-01-01 00:00:00

  • Motivation and social capital among prospective blood donors in three large blood centers in Brazil.

    abstract:BACKGROUND:Studies analyzing motivation factors that lead to blood donation have found altruism to be the primary motivation factor; however, social capital has not been analyzed in this context. Our study examines the association between motivation factors (altruism, self-interest, and response to direct appeal) and s...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03887.x

    authors: Gonçalez TT,Di Lorenzo Oliveira C,Carneiro-Proietti AB,Moreno EC,Miranda C,Larsen N,Wright D,Leão S,Loureiro P,de Almeida-Neto C,Lopes MI,Proietti FA,Custer B,Sabino E,NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), I

    更新日期:2013-06-01 00:00:00

  • Plasma treated with amotosalen and ultraviolet A light retains activity for hemostasis after 5 days post-thaw storage at 1 to 6o C.

    abstract:BACKGROUND:Plasma thawed and stored at 1 to 6° C for up to 5 days (thawed plasma [TP]) provides rapid availability in emergencies and reduces plasma waste, but it carries risks of coagulation factor loss or activation, bacterial outgrowth, and viral contamination. We characterized changes in amotosalen/ultraviolet A (U...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13973

    authors: Erickson A,Waldhaus K,David T,Huang N,Rico S,Corash L,Mufti N,Benjamin RJ

    更新日期:2017-04-01 00:00:00

  • Hematopoietic cell infusion-related adverse events in pediatric/small recipients in a prospective/multicenter study.

    abstract:BACKGROUND:Hematopoietic cell infusion-related adverse events (HCI-AEs) in hematopoietic stem cell transplantations (HSCTs) have been largely attributed to toxicity of dimethyl sulfoxide (DMSO) for cryopreservation, but HSC products also contain various cells and plasma components. Our recent prospective study of 1125 ...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/trf.15786

    authors: Ikeda K,Ohto H,Yamada-Fujiwara M,Okuyama Y,Fujiwara SI,Muroi K,Mori T,Kasama K,Kanamori H,Iseki T,Nagamura-Inoue T,Kameda K,Kanda J,Nagai K,Fujii N,Ashida T,Hirose A,Takahashi T,Minakawa K,Tanosaki R

    更新日期:2020-05-01 00:00:00

  • Improvement in appropriate autologous donations with local education: 1987 to 1989.

    abstract::Preoperative autologous blood donation for elective surgery patients at university hospitals was underused in the past. More recently, national educational efforts have been made. To test the impact of local surgeon interviews and education, in 1988 the same local educational program was instituted at three university...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1992.32692367202.x

    authors: Toy PT,McVay PA,Strauss RG,Stehling LC,Ahn DK

    更新日期:1992-07-01 00:00:00

  • Low incidence of D alloimmunization among patients with a serologic weak D phenotype after D+ transfusion.

    abstract:BACKGROUND:By consensus definition, the red blood cells (RBCs) of patients that react weak to 2+ in the serologic D test are classified as having the serologic weak D phenotype (weak D). The risk of D alloimmunization in patients with weak D is not well studied. This study retrospectively determined the incidence of D ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.13725

    authors: Yazer MH,Brunker PA,Bakdash S,Tobian AA,Triulzi DJ,Earnest V,Harris S,Delaney M

    更新日期:2016-10-01 00:00:00

  • In vivo recovery of human platelets in severe combined immunodeficient mice as a measure of platelet damage.

    abstract:BACKGROUND:Clinical performance of human platelet (PLT) products processed or stored under novel conditions is difficult to predict based on in vitro studies alone. Recovery and survival of radiolabeled PLTs in human subjects are used as surrogate markers for PLT efficacy in development of new products. Such experiment...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01295.x

    authors: Piper JT,Gelderman MP,Vostal JG

    更新日期:2007-08-01 00:00:00

  • Evaluation and improvement of blood donor educational materials: results from a multicenter randomized controlled trial.

    abstract:BACKGROUND:Blood collection centers are charged with creating donor educational materials (DnEM) that are easily understood across all prospective donor populations, while addressing mandates and recommendations from regulatory agencies and professional standard setting organizations. Donors must have sufficient inform...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15866

    authors: Wehrli G,Rossmann SN,Waxman DA,Katz LM

    更新日期:2020-08-01 00:00:00

  • The effect of hydroxyethyl starch on in vitro platelet and granulocyte function.

    abstract::The effect of hydroxyethyl starch (HES) on granulocyte and platelet functions was assessed. No alteration of granulocyte viability, morphology, phagocytic ability, or bactericidal capacity was detected after incubation with 6 per cent HES at 25 C for two hours. Platelet morphology, size distribution, aggregation, nucl...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1975.15576082223.x

    authors: Schiffer CA,Aisner J,Schmukler M,Whitaker CL,Wolff JH

    更新日期:1975-09-01 00:00:00

  • Are we underestimating reverse TRALI?

    abstract:BACKGROUND:Transfusion-related acute lung injury (TRALI) is a rare but serious adverse transfusion reaction and is known to be related to anti-human leukocyte antigen (HLA) or anti-human neutrophil antigen (HNA) antibodies in donor plasma. In 2016, four of eight reported TRALI cases could not be explained by donor anti...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15431

    authors: De Clippel D,Emonds MP,Compernolle V

    更新日期:2019-09-01 00:00:00

  • Acute nosocomial HCV infection detected by NAT of a regular blood donor.

    abstract:BACKGROUND:Routine HCV NAT of blood donors to detect persons in the preseroconversion phase of acute infection was introduced in Canada in October 1999. The source of virus exposure was investigated in the first, and to date only, blood donor found to be HCV NAT positive, anti-HCV negative in Canada. He was a regular d...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00112.x

    authors: Larke B,Hu YW,Krajden M,Scalia V,Byrne SK,Boychuk LR,Klein J

    更新日期:2002-06-01 00:00:00

  • Leukocyte depletion of red cell units at the bedside by transfusion through a new filter.

    abstract::Standard packed red cell (PRC) units can be depleted of leukocytes and platelets if they are transfused through a blood administration set in which the usual 170-mu filter has been replaced by a leukocyte removal filter (Sepacell R-500). During a 6-month period, 1550 PRC units were transfused through this filter in 61...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27587320533.x

    authors: Sirchia G,Rebulla P,Parravicini A,Carnelli V,Gianotti GA,Bertolini F

    更新日期:1987-09-01 00:00:00

  • Impact of delayed umbilical cord clamping on public cord blood donations: can we help future patients and benefit infant donors?

    abstract:BACKGROUND:Cord blood (CB) is a widely accepted stem cell source and its clinical utilization depends, to a great extent, on its cell content. Birth-to-clamping (BTC) time of umbilical cord determines placental transfusion to the newborn, and the remaining blood that can be collected and banked. The 2017 Committee Opin...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14574

    authors: Ciubotariu R,Scaradavou A,Ciubotariu I,Tarnawski M,Lloyd S,Albano M,Dobrila L,Rubinstein P,Grunebaum A

    更新日期:2018-06-01 00:00:00

  • Whole blood donors' post-donation symptoms diminish quickly but are discouraging: Results from 6-day symptom diaries.

    abstract:BACKGROUND:Whole blood donors may experience post-donation symptoms such as fatigue, dizziness, or headache after blood donation, which could influence donor retention. We aimed to examine post-donation symptoms during 1 week after whole blood donation, investigate donor characteristics associated with symptoms, and ev...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.16220

    authors: Sweegers MG,Twisk JWR,Quee FA,Ferguson E,van den Hurk K

    更新日期:2021-01-23 00:00:00

  • Hemotherapy bedside biovigilance involving vital sign values and characteristics of patients with suspected transfusion reactions associated with fluid challenges: can some cases of transfusion-associated circulatory overload have proinflammatory aspects?

    abstract:BACKGROUND:Monitoring of patients' vital sign values (VSVs) during hemotherapy may have an important role in the recognition and mitigation of transfusion-associated circulatory overload (TACO). Knowledge regarding VSVs and other patient characteristics in bedside-reported TACO or fluid challenge-suspected transfusion ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03595.x

    authors: Andrzejewski C Jr,Popovsky MA,Stec TC,Provencher J,O'Hearn L,Visintainer P,Steingrub J

    更新日期:2012-11-01 00:00:00

  • Neonatal alloimmune thrombocytopenia associated with maternal-fetal incompatibility for blood group B.

    abstract:BACKGROUND:Blood group A and B antigens are expressed only weakly on platelets (PLTs) of most individuals but are very strongly expressed on PLTs from approximately 1 percent of normal subjects (Type II high expressers). The implications of this trait for transfusion medicine are undefined. STUDY DESIGN AND METHODS:A ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01531.x

    authors: Curtis BR,Fick A,Lochowicz AJ,McFarland JG,Ball RH,Peterson J,Aster RH

    更新日期:2008-02-01 00:00:00

  • Exchange transfusion in sickle cell disease using a continuous-flow blood cell separator.

    abstract::An exchange transfusion was performed preoperatively on a patient with sickle cell disease using a continuous-flow blood cell separator. An exchange of 2,825 ml red blood cells achieved a hemoglobin A level of 90.8 per cent. The continuous-flow blood cell separator appears to offer a safe and effective method of excha...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1977.17377196364.x

    authors: Kernoff LM,Botha MC,Jacobs P

    更新日期:1977-05-01 00:00:00

  • Effect of delayed blood processing on the yield of factor VIII in cryoprecipitate and factor VIII concentrate.

    abstract::Current standards for the preparation of factor VIII (FVIII) concentrates from human plasma recommend separation of plasma from red cells (RBCs) within 6 hours of blood donation, thereby reducing the volume of plasma from donated whole blood available for processing to FVIII concentrate. The decay of FVIII clotting ac...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1988.28689059033.x

    authors: Hughes C,Thomas KB,Schiff P,Herrington RW,Polacsek EE,McGrath KM

    更新日期:1988-11-01 00:00:00

  • Improving platelet supply chains through collaborations between blood centers and transfusion services.

    abstract:BACKGROUND:Blood centers and hospital transfusion services are challenged with maintaining an adequate platelet (PLT) inventory to minimize the number of outdated units without risking a major shortage. A novel approach to inventory management was established at our institution through a collaboration between the Stanf...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02236.x

    authors: Fontaine MJ,Chung YT,Rogers WM,Sussmann HD,Quach P,Galel SA,Goodnough LT,Erhun F

    更新日期:2009-10-01 00:00:00

  • Bacterial screening of platelet components by National Health Service Blood and Transplant, an effective risk reduction measure.

    abstract:BACKGROUND:Bacterial contamination of blood components remains a major cause of sepsis in transfusion medicine. Between 2006 and 2010 in the 5 years before the introduction of bacterial screening of platelet (PLT) components by National Health Service Blood and Transplant (NHSBT), seven cases of PLT component-associate...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14085

    authors: McDonald C,Allen J,Brailsford S,Roy A,Ball J,Moule R,Vasconcelos M,Morrison R,Pitt T

    更新日期:2017-05-01 00:00:00

  • Bulk cryopreservation of lymphocytes in glycerol.

    abstract::The authors describe a method for freezing large amounts of peripheral blood lymphocytes (PBL) in a 20 percent glycerol solution. Between 0.6 and 4.3 X 10(9) cells in autologous plasma were frozen in polyethylene freezing bags in a final volume of 50 ml. The recovery after thawing averaged 89 +/- 14 percent with a mea...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1988.28288179020.x

    authors: Areman EM,Simonis TB,Carter CS,Read EJ,Klein HG

    更新日期:1988-03-01 00:00:00