Abstract:
BACKGROUND:To avoid the need, in serial apheresis donors, either to delay plateletpheresis until a predonation platelet count is completed or to obtain a postdonation count after each procedure, a statistical model has been developed to predict the postdonation platelet count from the donor predonation platelet count, weight, and hematocrit. STUDY DESIGN AND METHODS:Predonation and postdonation platelet counts were measured in two groups of approximately 100 consecutive donors (Group A to test the model and Group B to validate it), and the postdonation counts were calculated with the model. Using stepwise multiple linear regression from donor data, estimated postdonation platelet counts were found to be comparable to the postdonation platelet counts actually measured. RESULTS:Estimated postdonation platelet counts x 10(9) per L (mean +/- SD) for each group, respectively, were Group A, 195 +/- 35, versus actual platelet counts of 195 +/- 39 (p = 0.43), and Group B, 183 +/- 36, versus actual platelet counts of 189 +/- 34 (p = 0.14). Sensitivity and specificity, respectively, were Group A, 57 and 99 percent and Group B, 62 and 99 percent. CONCLUSION:For most serial apheresis donors, application of this predictor model should preclude the need to obtain an extra postdonation platelet count.
journal_name
Transfusionjournal_title
Transfusionauthors
Cabezudo I,Winegarden DK,Randels MJ,Strauss RGdoi
10.1046/j.1537-2995.1994.34194098605.xsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
54-7issue
1eissn
0041-1132issn
1537-2995journal_volume
34pub_type
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