Metabolic impact of red blood cell exchange with rejuvenated red blood cells in sickle cell patients.

abstract：BACKGROUND:Antibodies produced against the D antigen make use of IGHV genes restricted to the IGHV3 superfamily. These findings are based on the IGHV gene analysis in anti-D-producing B cells from hyperimmunized donors, however, and therefore the restriction might be due to the hyperimmunization. In this study the IGHV...

journal_title：Transfusion

authors： Dohmen SE,Verhagen OJ,Muit J,Ligthart PC,van der Schoot CE

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Treating hemorrhage with blood transfusions in subjects previously hemodiluted with different colloidal plasma expanders, using fresh autologous blood or blood that has been stored for 2 weeks, allows identifying the interaction between type of plasma expander and differences in blood storage. STUDY DESIGN ...

journal_title：Transfusion

authors： Hightower CM,Salazar Vázquez BY,Cabrales P,Tsai AG,Acharya SA,Intaglietta M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:After multiple transfusions, the serologic typing of autologous blood group phenotypes is difficult, because of mixed RBC populations. The genotyping of ABO, Rh, Kell, Kidd, and Duffy systems could be used to determine autologous blood group antigen status. STUDY DESIGN AND METHODS:Blood samples from patien...

journal_title：Transfusion

authors： Rozman P,Dovc T,Gassner C

更新日期：2000-08-01 00:00:00

abstract：:The introduction of plerixafor as a peripheral blood stem cell mobilization agent has allowed more patients with multiple myeloma, non-Hodgkin's lymphoma, and Hodgkin's disease to mobilize sufficient hematopoietic progenitor cells (HPCs) to proceed to autologous transplantation. Because of the high cost of plerixafor,...

journal_title：Transfusion

authors： Tanhehco YC,Vogl DT,Stadtmauer EA,O'Doherty U

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Bartonella spp. are neglected fastidious Gram-negative bacilli. We isolated Bartonella henselae from 1.2% of 500 studied blood donors and demonstrated that the bacteria remain viable in red blood cell units after 35 days of experimental infection. Now, we aim to evaluate the possibility of B. henselae transm...

journal_title：Transfusion

authors： Silva MN,Vieira-Damiani G,Ericson ME,Gupta K,Gilioli R,de Almeida AR,Drummond MR,Lania BG,de Almeida Lins K,Soares TC,Velho PE

更新日期：2016-06-01 00:00:00

abstract：:The authors describe a method for freezing large amounts of peripheral blood lymphocytes (PBL) in a 20 percent glycerol solution. Between 0.6 and 4.3 X 10(9) cells in autologous plasma were frozen in polyethylene freezing bags in a final volume of 50 ml. The recovery after thawing averaged 89 +/- 14 percent with a mea...

journal_title：Transfusion

authors： Areman EM,Simonis TB,Carter CS,Read EJ,Klein HG

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Plasma is commonly used for vitamin K antagonist (VKA) reversal, but observational studies suggest that it is associated with transfusion-related adverse reactions (e.g., volume overload). However, this issue has not previously been addressed in a randomized controlled trial (RCT). STUDY DESIGN AND METHODS:...

journal_title：Transfusion

authors： Refaai MA,Goldstein JN,Lee ML,Durn BL,Milling TJ Jr,Sarode R

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Jra is a high-frequency antigen seen in all populations, but the clinical significance of Jra antibodies is incompletely understood. Two cases are reported in which patients with anti-Jra received incompatible transfusions. CASE REPORTS:A 69-year-old Japanese man had anti-K and anti-Jra. Despite multiple tr...

journal_title：Transfusion

authors： Kwon MY,Su L,Arndt PA,Garratty G,Blackall DP

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Most alloantigens on transfused red blood cells (RBCs) are weakly immunogenic, with only a 2 to 6 percent overall immunization rate even in patients receiving multiple transfusions. Although recipient genetics may contribute to responder and/or nonresponder status, in most cases HLA type does not predict hum...

journal_title：Transfusion

authors： Hendrickson JE,Desmarets M,Deshpande SS,Chadwick TE,Hillyer CD,Roback JD,Zimring JC

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Transfusion of platelet concentrates (PCs) is the basic treatment for severe platelet disorders. PCs carry the risk of pathogen transmission, especially bacteria. Pathogen reduction (PR) by addition of photochemical reagents and irradiation with visible or ultraviolet (UV) light can significantly reduce this...

journal_title：Transfusion

authors： Mohr H,Steil L,Gravemann U,Thiele T,Hammer E,Greinacher A,Müller TH,Völker U

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Coxiella burnetii, an obligate intracellular organism, is the causative agent of the zoonotic disease Q fever. The seroprevalence rate for Q fever in the United States is 3.1%, suggesting a high number of infections each year. However, fewer than 200 cases of Q fever are reported to the CDC annually. This di...

journal_title：Transfusion

authors： Kersh GJ,Priestley R,Massung RF

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The infusion of citrate during apheresis may affect the levels of ionized magnesium in the blood. Hypomagnesemia and concomitant hypocalcemia could influence the parathormone response and could be responsible for some of the symptoms observed during apheresis. STUDY DESIGN AND METHODS:The study reports meas...

journal_title：Transfusion

authors： Mercan D,Bastin G,Lambermont M,Dupont E

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Recent blood shortages and the potential clinical impact of red blood cell (RBC) age highlight the need to understand blood supply delivery. This study addresses the characteristics and mechanics of RBC unit trafficking and storage across the transfusion service, previously undescribed in the literature. ST...

journal_title：Transfusion

authors： Cheng CK,Trethewey D,Sadek I

更新日期：2010-01-01 00:00:00

abstract：:The enzyme-linked antiglobulin test was used to determine the percentage of antibody removed from sensitized red cells by five elution methods: Rubin ether, xylene, digitonin-acid, glycine, and heat. Antibodies examined in the study included anti-D, -c, -E, and -K. With two examples of anti-D, more antibody was eluted...

journal_title：Transfusion

authors： Gibble JW,Salamon JL,Ness PM

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Standard plateletpheresis techniques and effects on platelet (PLT) donors were investigated to provide an informative basis for advancement of apheresis software. STUDY DESIGN AND METHODS:Three paired groups with 33 male and 22 female blood donors were prospectively investigated by analyzing blood counts of...

journal_title：Transfusion

authors： Strasser EF,Schuster M,Egler K,Bauer J,Weisbach V,Ringwald J,Zimmermann R,Zingsem J,Eckstein R

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The Q fever outbreaks in the Netherlands in 2007 to 2009 initiated discussion on the necessity of measures to prevent transmission through blood products. Risk assessments help transfusion regulators decide when and where measures are required. This study assesses the transfusion transmission (TT) risk of Q ...

journal_title：Transfusion

authors： Oei W,Kretzschmar ME,Zaaijer HL,Coutinho R,van der Poel CL,Janssen MP

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Reported hepatitis E virus (HEV) antibody assay performance characteristics are variable. Using a subset of surplus US blood donation samples, we compared assays for detecting anti-HEV immunoglobulin M (Ig)M and IgG or total anti-HEV antibodies. STUDY DESIGN AND METHODS:Samples from 5040 random blood donati...

journal_title：Transfusion

authors： Zafrullah M,Zhang X,Tran C,Nguyen M,Kamili S,Purdy MA,Stramer SL

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Throughout history, blood has been embedded with powerful and paradoxical connotations. In the last decades, a more rational conception based on scientific knowledge has emerged, portraying blood as a "disenchanted" and utilitarian object, hence more apt for donation between strangers. This study aims to exa...

journal_title：Transfusion

authors： Charbonneau J,Tran NY

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Immunoglobulin (Ig)G replacement with intravenous or subcutaneous immunoglobulins is a lifelong substitutive therapy in patients with primary antibody deficiencies (PADs). Hemolysis after immunoglobulin therapy was described in patients receiving high immunoglobulin dosages. The issue of hemolysis after immu...

journal_title：Transfusion

authors： Quinti I,Pulvirenti F,Milito C,Granata G,Giovannetti G,La Marra F,Pesce AM,Farrugia A,Coluzzi S,Girelli G

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:High-dose therapy with autologous stem cell support after standard dose induction is a promising approach for therapy of primary central nervous system lymphoma (PCNSL). High-dose methotrexate (HD-MTX) is a standard drug for induction of PCNSL; however, data about the capacity of HD-MTX plus granulocyte-colo...

journal_title：Transfusion

authors： Kiefer T,Krüger WH,Montemurro M,Schüler F,Hirt C,Pasold R,Niederwieser D,Schwenke M,Dölken G

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Development of de novo alloantibodies against recipient's red blood cell (RBC) antigens by engrafted donor's lymphocytes is a known phenomenon in the setting of allogeneic hematopoietic stem cell transplantation (HSCT). This situation is usually clinically insignificant. We report a case of early clinically ...

journal_title：Transfusion

authors： Bailén R,Kwon M,Pérez-Corral AM,Pascual C,Buño I,Balsalobre P,Serrano D,Gayoso J,Díez-Martín JL,Anguita J

更新日期：2017-10-01 00:00:00

abstract：:An apparent anti-Jka, reacting only in the presence of methyl esters of hydroxybenzoic acid (HBA), was detected in an individual with Jk (a+) red blood cells. The antibody was first detected when a commercial low-ionic-strength-solution preparation containing the preservative methyl paraben (a methyl ester of hydroxyb...

journal_title：Transfusion

authors： Halima D,Garratty G,Bueno R

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:The AMICUS (Fenwal, Inc.) was cleared in the United States for platelet (PLT) and plasma collection in 1996 with subsequent clearances for the collection of other blood products. Although not previously used for therapeutic plasma exchange (TPE), new disposables, software, and hardware were developed to enab...

journal_title：Transfusion

authors： Winters JL,Burgstaler EA,Gottschall JL,Balogun RA,Houghton JR,Lee WJ,Snyder EL

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Data on red blood cell (RBC) transfusion in the United States show variation in practice and overprescribing or overdosing is considered to be prevalent. Education or restrictive interventions could modify practice. STUDY DESIGN AND METHODS:RBC transfusion and mortality rates were recorded in a single insti...

journal_title：Transfusion

authors： Tavares MM,Diquattro PJ,Sweeney JD

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Adequate administration of Rh immune globulin requires an accurate determination of the number of D-positive cells in the circulation of D-negative women. Although several tests have been described for the detection of fetomaternal hemorrhage, there is still a need for a rapid, simple, and clinically relevan...

journal_title：Transfusion

authors： Salama A,David M,Wittmann G,Stelzer A,Dudenhausen JW

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:An ongoing issue in transfusion medicine is whether newly identified or emerging pathogens can be transmitted by transfusion. One method to study this question is through the use of a contemporary linked donor-recipient repository. STUDY DESIGN AND METHODS:The Retrovirus Epidemiology Donor Study Allogeneic ...

journal_title：Transfusion

authors： Kleinman SH,Glynn SA,Higgins MJ,Triulzi DJ,Smith JW,Nass CC,Garratty G,Murphy EL,LeParc GF,Schreiber GB,King MR,Chamberland ME,Nemo GJ

更新日期：2005-07-01 00:00:00

abstract：:In the procedure for quality control of red cell concentrates, made white cell (WBC)-poor by filtration, the particle-counting technique was found to be insufficiently sensitive in detecting the remaining WBCs and platelets. Therefore, direct radioimmunoassays were developed using murine monoclonal antibodies specific...

journal_title：Transfusion

authors： Webster MR,Prins HK,Huisman JG

更新日期：1990-02-01 00:00:00

abstract：:The glycerol concentration of frozen-thawed red cells must be less than 2 percent to prevent hemolysis upon transfusion. Three methods were investigated for monitoring the glycerol concentration of frozen-thawed red cells prepared by the agglomeration technique. The supernatant osmolality and glycerol concentration we...

journal_title：Transfusion

authors： Bongiovanni MB,Hughlett MA,Wurzel HA

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Preliminary evidence of cases of acute occult hepatitis B virus (HBV) infection (OBI) has been recently reported in the literature. Furthermore, OBI definition has been the object of an international consensus conference. STUDY DESIGN AND METHODS:A case of acute primary OBI was identified and followed up in...

journal_title：Transfusion

authors： Manzini P,Abate ML,Valpreda C,Milanesi P,Curti F,Rizzetto M,Smedile A

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Serious complications of blood donation are rare. Reported here is a significant vascular event that resulted from whole-blood phlebotomy and required surgical repair. CASE REPORT:A 49-year-old woman donated whole blood without incident in November 1992, but reported ecchymosis and tenderness in the antecub...

journal_title：Transfusion

authors： Popovsky MA,McCarthy S,Hawkins RE

更新日期：1994-03-01 00:00:00