Transfusion-associated Chagas disease (American trypanosomiasis) in Mexico: implications for transfusion medicine in the United States.

Abstract:

BACKGROUND:Trypanosoma cruzi, the protozoan cause of Chagas disease, causes life-long infection and is easily transmitted by blood transfusion. Our goals were to determine the prevalence of Chagas disease among donors in five Mexican blood banks, to look for evidence of transmission of T. cruzi by transfusion, and to evaluate two serologic assays for Chagas disease. STUDY DESIGN AND METHODS:Blood samples from donors were tested initially with the Abbott Chagas EIA or the Meridian Chagas' IgG ELISA. Samples giving readings that were at least 50% of the cutoffs were run in a confirmatory radioimmune precipitation assay (RIPA), as were samples from recipients of blood products from RIPA-positive donors. RESULTS:The overall prevalence of Chagas disease was 1/133 (55/7,296; 0.75%). In addition, 4 of 9 surviving recipients of blood products from T. cruzi-infected donors were in turn infected. Using the manufacturers' recommended cutoffs, the sensitivity and specificity of the Abbott test were 92.0% (23/25) and 99.8% (2,865/2,872) respectively, and the corresponding values for the Meridian assay were 70.0% (21/30) and 100.0% (4,369/4,369). CONCLUSIONS:These findings indicate clearly that transfusion-associated transmission of T. cruzi is occurring in the study areas. Serologic testing of blood donors for Chagas disease should be performed there and in the rest of Mexico. The two screening assays evaluated may lack the accuracy necessary for blood donor testing when used as suggested by the manufacturers.

journal_name

Transfusion

journal_title

Transfusion

authors

Kirchhoff LV,Paredes P,Lomelí-Guerrero A,Paredes-Espinoza M,Ron-Guerrero CS,Delgado-Mejía M,Peña-Muñoz JG

doi

10.1111/j.1537-2995.2006.00715.x

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

298-304

issue

2

eissn

0041-1132

issn

1537-2995

pii

TRF00715

journal_volume

46

pub_type

杂志文章
  • Parvovirus B19 transmission by a high-purity factor VIII concentrate.

    abstract:BACKGROUND:Parvovirus B19 (B19) is known to cause a variety of human diseases in susceptible individuals by close contact via the respiratory route or by transfusion of contaminated blood or blood products. In this study, whether a case of B19 transmission was causally related to the infusion of implicated lots of a so...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.04387.x

    authors: Wu CG,Mason B,Jong J,Erdman D,McKernan L,Oakley M,Soucie M,Evatt B,Yu MY

    更新日期:2005-06-01 00:00:00

  • Transfusion reactions in pediatric compared with adult patients: a look at rate, reaction type, and associated products.

    abstract:BACKGROUND:The majority of reports on transfusion reactions address adult patients. Less is known about the types, incidence, and other clinical details of transfusion reactions in pediatric populations. Furthermore, to our knowledge, there have been no previous reports directly comparing these aspects between adults a...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12827

    authors: Oakley FD,Woods M,Arnold S,Young PP

    更新日期:2015-03-01 00:00:00

  • Primary structure of human neutrophil antigens 1a and 1b.

    abstract:BACKGROUND:Neutrophil specific Fcγ receptor IIIb (CD16b) is a low-affinity IgG receptor. Its polymorphic variants are associated with human neutrophil antigens (HNA). HNA-1a and HNA-1b differ in four amino acids. Immunization can lead to the production of alloantibodies. The exact contribution of four amino acid exchan...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15707

    authors: Sachs UJ,Radke C,Bein G,Grabowski C,Simtong P,Bux J,Bayat B,Reil A

    更新日期:2020-04-01 00:00:00

  • A review on decision support for massive transfusion: understanding human factors to support the implementation of complex interventions in trauma.

    abstract:BACKGROUND:Critically bleeding trauma patients require coordinated and efficient decision-making processes to ensure optimal management of their massive transfusion (MT) requirements. Human factors (HFs) is a discipline that investigates factors influencing work processes from the organizational, group, and individual ...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2012.03648.x

    authors: Enticott JC,Jeffcott S,Ibrahim JE,Wood EM,Cole-Sinclair M,Fitzgerald M,Cameron PA,Phillips LE

    更新日期:2012-12-01 00:00:00

  • Collection and immunoselection of CD34+ cells: the impact of age, sex, and diabetes in patients with chronic heart failure.

    abstract:BACKGROUND:Mobilized peripheral blood is the most common source of CD34+ cells intended for transplantations. The collection and enrichment of CD34+ cells could be affected by various factors and there are some controversies regarding the effects of patient-related factors. The aim of this study was to assess the impac...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章

    doi:10.1111/trf.13646

    authors: Kresnik PK,Krasna M,Rozman P,Vrtovec B,Malicev E

    更新日期:2016-07-01 00:00:00

  • Filtration of methylene blue-photooxidized plasma: influence on coagulation and cellular contamination.

    abstract:BACKGROUND:Virus inactivation of plasma can be achieved by photodynamic methods in the presence of phenothiazine dyes such as methylene blue (MB). Subsequent filtration may increase the efficacy of virus inactivation and reduce adverse effects of WBC contamination and MB. STUDY DESIGN AND METHODS:This study examined t...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2001.41010082.x

    authors: Riggert J,Humpe A,Legler TJ,Wolf C,Simson G,Köhler M

    更新日期:2001-01-01 00:00:00

  • Immune hemolytic anemia associated with teicoplanin.

    abstract:BACKGROUND:Several drugs can cause immune hemolytic anemia. Here a patient who developed hemolytic anemia after treatment with teicoplanin is described. CASE REPORT:Owing to a two-vessel disease, a 68-year-old white man underwent coronary artery bypass grafting. He was readmitted for superficial sternal wound infectio...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.0041-1132.2003.00599.x

    authors: Coluccio E,Villa MA,Villa E,Morelati F,Revelli N,Paccapelo C,Garratty G,Rebulla P

    更新日期:2004-01-01 00:00:00

  • A systematic review and survey of the management of unexpected neonatal alloimmune thrombocytopenia.

    abstract:BACKGROUND:Unexpected neonatal alloimmune thrombocytopenia (NAIT) may have devastating consequences and its management is challenging. To design future trials, evidence from the literature and existing best practice need review. STUDY DESIGN AND METHODS:This study was a cross-sectional survey of neonatal units in Germ...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2007.01486.x

    authors: Bassler D,Greinacher A,Okascharoen C,Klenner A,Ditomasso J,Kiefel V,Chan A,Paes B

    更新日期:2008-01-01 00:00:00

  • Consequences and costs of noncompliance with iron chelation therapy in patients with transfusion-dependent thalassemia: a literature review.

    abstract:BACKGROUND:Patients with thalassemia major require iron chelation therapy (ICT) to prevent complications from transfusional iron overload. Deferoxamine is effective, but requires administration as a slow continuous subcutaneous or intravenous infusion five to seven times per week. Deferiprone is a three-times-daily ora...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/j.1537-2995.2007.01416.x

    authors: Delea TE,Edelsberg J,Sofrygin O,Thomas SK,Baladi JF,Phatak PD,Coates TD

    更新日期:2007-10-01 00:00:00

  • Blood group A immunodeterminants on human red cells differ in biologic activity and sensitivity to alpha-N-acetylgalactosaminidase.

    abstract:BACKGROUND:Epitopes of blood group A antigen can be enzymatically cleaved from red cells (RBCs), but the extent of cleavage required for normal survival in allogeneic blood transfusion recipients is unknown. Therefore, the cleavage rates were studied for A antigen epitope binding of 1) complement-activating anti-A, 2) ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1995.351096026361.x

    authors: Hoskins LC,Larson G,Naff GB

    更新日期:1995-10-01 00:00:00

  • A simple method for preparation of C3c fragment from trypsinized serum-reacted zymosan.

    abstract::A simple method for preparing relatively pure C3c fragment from serum-reacted zymosan is described. Although hyperimmunization studies indicate contamination of the "C3c" product by C3d and immunoglobulin antigenic materials, these are present in such small amounts that they do not impair the effectiveness of the prod...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1980.20380214904.x

    authors: Chaplin H Jr,Hoffmann NL,Monroe MC

    更新日期:1980-05-01 00:00:00

  • Validation and assessment of a blood-donor arm disinfectant containing chlorhexidine and alcohol.

    abstract:BACKGROUND:To minimize the bacterial contamination rate in blood collected from donors, a study was designed to evaluate the suitability of a single-use chlorhexidine-alcohol antiseptic for donor arm preparation at all blood collection venues in Australia. STUDY DESIGN AND METHODS:A prospective study of bacterial load...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.03362.x

    authors: Wong PY,Colville VL,White V,Walker HM,Morris RA,Microbial Contamination and Infection Control Subcommittee, Australian Red Cross Blood Service.

    更新日期:2004-08-01 00:00:00

  • Impact of leukapheresis on early death rate in adult acute myeloid leukemia presenting with hyperleukocytosis.

    abstract:BACKGROUND:Patients with acute myeloid leukemia (AML) with hyperleukocytosis of at least 100 x 10(9) per L are at high risk of early death due to pulmonary or cerebral leukostasis. Although the efficacy of leukapheresis in terms of prompt cytoreduction is generally accepted, published data regarding the clinical value ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01406.x

    authors: Bug G,Anargyrou K,Tonn T,Bialleck H,Seifried E,Hoelzer D,Ottmann OG

    更新日期:2007-10-01 00:00:00

  • Changes in minimum hemoglobin and interdonation interval: impact on donor hemoglobin and donation frequency.

    abstract:BACKGROUND:To reduce donor iron deficiency in whole blood donors, we changed our hemoglobin (Hb) cutoff in males and interdonation interval in females. STUDY DESIGN AND METHODS:A change in messaging to females in fall 2016 was followed by changing the interdonation interval from 56 to 84 days in the appointment bookin...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15155

    authors: Goldman M,Yi QL,Steed T,O'Brien SF

    更新日期:2019-05-01 00:00:00

  • Human T-lymphotropic virus type I and type II infections and correlation with risk factors in blood donors from São Paulo, Brazil.

    abstract:BACKGROUND:Little is known about the prevalence of and risk factors for human T-lymphotropic virus type I and type II (HTLV-I, HTLV-II) infections in Brazil. STUDY DESIGN AND METHODS:Sera from 17,063 healthy Brazilian donors were screened by enzyme-linked immunosorbent assay for antibody to HTLV-I/II between August 19...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1995.35395184284.x

    authors: Ferreira Júnior OC,Vaz RS,Carvalho MB,Guerra C,Fabron AL,Rosemblit J,Hamerschlak N

    更新日期:1995-03-01 00:00:00

  • Delayed hemolytic transfusion reaction caused by anti-P1 antibody.

    abstract::A 67-year-old white woman received transfusions of a total of 87 units of whole blood and red blood cells during and within 48 hours following a pneumonectomy. Although she had previously received blood transfusions, unexpected antibodies were not detectable by routine screening. On the second postoperative day, she d...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1981.21181127489.x

    authors: Chandeysson PL,Flye MW,Simpkins SM,Holland PV

    更新日期:1981-01-01 00:00:00

  • Detection of bacterial contamination of platelet components: six years' experience with the BacT/ALERT system.

    abstract:BACKGROUND:Hemovigilance has shown that bacteria cause more fatalities than other infections together. Surveillance for detection of bacteria in platelets (PLTs) was initiated. Concomitantly, the storage period for PLTs was extended from 5 to 7 days to reduce cost. STUDY DESIGN AND METHODS:Analysis was performed of al...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.04019.x

    authors: Munksgaard L,Albjerg L,Lillevang ST,Gahrn-Hansen B,Georgsen J

    更新日期:2004-08-01 00:00:00

  • Computerized selection of donors for inclusion in red cell antibody panels.

    abstract::This study evaluated various algorithms for the generation of a red cell antibody identification panel by computer. The algorithms depended on schemes that optimized Fisher's exact p value for each specificity in the panel rather than using predetermined formulations of desired phenotypic combinations. Panels produced...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27187121480.x

    authors: AuBuchon JP,Roberts GC

    更新日期:1987-01-01 00:00:00

  • Evaluation of immunohematologic routine methods using the new erythrocyte-magnetized technology on the QWALYS 2 system.

    abstract:BACKGROUND:QWALYS 2 is a fully automated system for ABO/D grouping, Rh phenotyping, K typing, and antibody screening (ABS). Its new erythrocyte-magnetized technology (EMT) is based on the use of magnetic nanoparticles and avoids centrifugation and washing steps. STUDY DESIGN AND METHODS:Overall 499 blood samples were ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02136.x

    authors: Schoenfeld H,Bulling K,von Heymann C,Neuner B,Kalus U,Kiesewetter H,Pruss A

    更新日期:2009-07-01 00:00:00

  • Effect of delayed centrifugation or reading on the detection of ABO incompatibility by the immediate-spin crossmatch.

    abstract::The immediate-spin (IS) crossmatch is a method that detects ABO incompatibility. However, under certain circumstances, this test may show unwanted negative or weak results, even though the red cells (RBCs) and serum being tested are ABO incompatible with each other. The present study investigated the potential effect ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1991.31391165166.x

    authors: Shulman IA,Calderón C

    更新日期:1991-03-01 00:00:00

  • Laboratory diagnosis of heparin-associated thrombocytopenia and comparison of platelet aggregation test, heparin-induced platelet activation test, and platelet factor 4/heparin enzyme-linked immunosorbent assay.

    abstract:BACKGROUND:As clinical diagnosis of heparin-associated thrombocytopenia (HAT) is often difficult, confirmation by sensitive laboratory assays is desirable. STUDY DESIGN AND METHODS:The sensitivity of the heparin-induced platelet activation (HIPA) test and the platelet aggregation test (PAT) was prospectively compared ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1994.34594249047.x

    authors: Greinacher A,Amiral J,Dummel V,Vissac A,Kiefel V,Mueller-Eckhardt C

    更新日期:1994-05-01 00:00:00

  • Effect of blood donation on the establishment of normal ranges of lymphocyte subsets.

    abstract:BACKGROUND:Absolute counts of CD4+ T-lymphocytes are used in the management of patients with human immunodeficiency virus infection. Low absolute counts of CD3+CD4+ cells have also been observed in healthy people--a phenomenon called idiopathic CD4 lymphocytopenia. It is common practice for normal ranges for lymphocyte...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1996.36696269517.x

    authors: Bryant JA,Wylie BR,Yuan FF,Ribeiro A,Thomson AR,Cooley MA,Fletcher A

    更新日期:1996-06-01 00:00:00

  • The impact of universal leukodepletion of the blood supply on hemovigilance reports of posttransfusion purpura and transfusion-associated graft-versus-host disease.

    abstract:BACKGROUND:The pathogenesis of posttransfusion purpura (PTP) and transfusion-associated graft-versus-host disease (TA-GVHD) involves patient exposure to donor platelets (PLTs) and T lymphocytes, respectively, which are removed during blood component leukodepletion (LD). STUDY DESIGN AND METHODS:Reports of PTP and TA-G...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01281.x

    authors: Williamson LM,Stainsby D,Jones H,Love E,Chapman CE,Navarrete C,Lucas G,Beatty C,Casbard A,Cohen H

    更新日期:2007-08-01 00:00:00

  • Risk of exposure to blood products during pregnancy: guidance for Zika and other donor deferral policies.

    abstract:BACKGROUND:Exposure to blood products during pregnancy carries a potential risk of transfusion transmission of infectious agents. Blood agencies have historically sought optimal deferral and testing strategies to protect blood supplies in part to ensure the protection of pregnant women and their unborn infants. The Zik...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.14001

    authors: Murphy MS,Shehata N,Colas JA,Chassé M,Fergusson DA,O'Brien SF,Goldman M,Tinmouth A,Forster AJ,Wilson K

    更新日期:2017-03-01 00:00:00

  • Evaluation of riboflavin photochemical treatment for inactivation of HCT116 tumor cells mixed in simulative intraoperative salvage blood.

    abstract:BACKGROUND:Radiation and filtration have achieved satisfactory results in inactivation or removal of tumor cells mixed in salvage blood, but some drawbacks remain. This study evaluated the inactivation on HCT116 cells mixed in simulative salvage blood by riboflavin photochemical treatment. METHODS:HCT116 cells were ad...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15499

    authors: Yu Y,Yang L,He C,Tai S,Ma C,Yang T,Wang D

    更新日期:2019-10-01 00:00:00

  • Emm. A red cell antigen of very high frequency.

    abstract::Anti-Emm, an antibody to a public red cell antigen, was found in the serums of four Emm-propositi and in the serum of the Emm-brother of one of them. Three of the propositi were men, and their antibodies, as well as that of the compatible brother, were believed to be "naturally occurring." Since there are two Emm-sibl...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1987.27487264738.x

    authors: Daniels GL,Taliano V,Klein MT,McCreary J

    更新日期:1987-07-01 00:00:00

  • Effect of plasma processing and storage on microparticle abundance, nitric oxide scavenging, and vasoactivity.

    abstract:BACKGROUND:We set out to define the impact of collection, processing, and storage on plasma product microparticle (MP) abundance, potential for nitric oxide (NO) scavenging, and vasoactivity. STUDY DESIGN AND METHODS:Three currently US licensed products were tested: liquid plasma (LP), fresh frozen plasma (FFP), and s...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15214

    authors: Rogers SC,Moynihan FT 4th,McDonough R,Timm DD,Hovmand-Warner E,Frazier E,Thomas KA,Spinella PC,Doctor A

    更新日期:2019-04-01 00:00:00

  • Photodynamic sterilization of red cells and its effect on contaminating white cells: viability and mechanism of cell death.

    abstract:BACKGROUND:Phthalocyanines are useful sensitizers for photodynamic sterilization of red cell concentrates. Various lipid-enveloped viruses can be inactivated with only limited red cell damage. Because white cells are involved in the immunomodulatory effects of blood transfusions, the study of the effect of photodynamic...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1999.39060599.x

    authors: Moor AC,van der Veen A,Dubbelman TM,VanSteveninck J,Brand A

    更新日期:1999-06-01 00:00:00

  • Sources and sequelae of bacterial contamination of hematopoietic stem cell components: implications for the safety of hematotherapy and graft engineering.

    abstract:BACKGROUND:It is important to compare the incidence of bacterial contamination of components collected from the peripheral blood or bone marrow (BM), as well as of components processed with or without cell selection or depletion, and to evaluate the sequelae of such contamination. STUDY DESIGN AND METHODS:Bacterial co...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1996.36996420753.x

    authors: Webb IJ,Coral FS,Andersen JW,Elias AD,Finberg RW,Nadler LM,Ritz J,Anderson KC

    更新日期:1996-09-01 00:00:00

  • Flow cytometric quantitation of serum anti-D in pregnancy.

    abstract:BACKGROUND:The major cause of fetal hemolytic disease is maternal immunization to D in D-incompatible pregnancies. To prevent complications, D-incompatible pregnancies are monitored for the level of maternal anti-D. At present, the monitoring of anti-D levels is performed by the indirect antiglobulin test complemented ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1996.36696269507.x

    authors: Christensson M,Bremme K,Shanwell A,Westgren M,Christensson B

    更新日期:1996-06-01 00:00:00