Abstract:
BACKGROUND:Long-lasting insecticidal nets are an effective tool for malaria prevention, and "universal coverage" with such nets is increasingly the goal of national malaria control programmes. However, national level campaigns in several countries have run out of nets in the course of distribution, indicating a problem in the method used to estimate the quantity needed. PRESENTATION OF HYPOTHESIS:A major reason for the shortfall in estimation is the mismatch between the quantification factor used to plan procurement and the allocation algorithm used at community level, in particular the effect of needing to add an additional net to households with an odd number of inhabitants. To solve this problem a revised quantification factor is suggested. TESTING HYPOTHESIS:Based on data from a broad range of household surveys across Africa, the effect of odd-numbered households on numbers of nets distributed is estimated via two frequently used allocation methods. The impact of these algorithms on the proportion of households reaching a person to net ratio of 2:1, a frequently used marker of universal coverage is then calculated. IMPLICATIONS:In order to avoid stock-outs of nets during national coverage campaigns, it is recommended to use a quantification factor of 1.78 people per net, with an additional allocation factor suggested to account for other common problems at the community level resulting in a final recommended ratio of 1.60 people per net. It is also recommend that community level allocation procedures be aligned with procurement estimates to reduce shortages of nets during campaign distributions. These analyses should enable programme managers to make evidence-based decisions and support a more efficient and effective use of LLIN distribution campaign resources.
journal_name
Malar Jjournal_title
Malaria journalauthors
Kilian A,Boulay M,Koenker H,Lynch Mdoi
10.1186/1475-2875-9-330subject
Has Abstractpub_date
2010-11-18 00:00:00pages
330issn
1475-2875pii
1475-2875-9-330journal_volume
9pub_type
杂志文章相关文献
MALARIA JOURNAL文献大全abstract:BACKGROUND:Deltamethrin-impregnated, long-lasting insecticidal nets (LLINs) were distributed in the study area from November 2014 to January 2015 to evaluate their impact on malaria transmission in the presence of insecticide-resistant vectors. Studies were carried out in 16 selected clusters in Keshkal sub-district, C...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2557-1
更新日期:2018-11-08 00:00:00
abstract:BACKGROUND:Malaria represents a huge burden for the health care services across Africa. Describing malaria attending health services contributes to quantify the burden and describe the epidemiology and clinical presentation. METHODS:Retrospective analysis of data collected through the Manhiça morbidity surveillance sy...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-7-36
更新日期:2008-02-26 00:00:00
abstract:BACKGROUND:Plasmodium falciparum malaria is a significant problem around the world today, thus there is still a need for new control methods to be developed. Because the sporozoite displays dual infectivity for both the mosquito salivary glands and vertebrate host tissue, it is a good target for vaccine development. M...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-80
更新日期:2012-03-23 00:00:00
abstract::Malaria is a public health problem in French Guiana. Plasmodium vivax is the most frequent parasite. The objective of this analysis was to estimate the proportion of relapses in the burden of vivax malaria using the statistical rule stating that any case of vivax malaria occurring less than 90 days following a first e...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-367
更新日期:2013-10-24 00:00:00
abstract::After publication of the article [1], it has been brought to our attention that a funding acknowledgement has been omitted from the original article. The authors would like to include the following, "The study was undertaken as part of the Target Malaria consortium, which receives core funding from the Bill & Melinda ...
journal_title:Malaria journal
pub_type: 已发布勘误
doi:10.1186/s12936-017-2030-6
更新日期:2017-09-19 00:00:00
abstract:BACKGROUND:Reported malaria cases continue to decline globally, and this has been attributed to strategic implementation of multiple malaria control tools. Gains made would however need to be sustained through continuous monitoring to ensure malaria elimination and eradication. Entomological inoculation rate (EIR) is c...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-103
更新日期:2014-03-17 00:00:00
abstract:BACKGROUND:In the context of malaria elimination/eradication, drugs that are effective against the different developmental stages of the parasite are highly desirable. The oldest synthetic anti-malarial drug, the thiazine dye methylene blue (MB), is known for its activity against Plasmodium blood stages, including game...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2300-y
更新日期:2018-04-03 00:00:00
abstract:BACKGROUND:Mexico is in the malaria pre-elimination phase; therefore, continuous assessment and understanding of the social and behavioural risk factors related to exposure to malaria are necessary to achieve the overall goal. The aim of this research was to investigate socio-economic backgrounds, attitudes and practic...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-157
更新日期:2014-04-23 00:00:00
abstract:BACKGROUND:Malaria is a major public health burden in Southeastern Bangladesh, particularly in the Chittagong Hill Tracts region. Malaria is endemic in 13 districts of Bangladesh and the highest prevalence occurs in Khagrachari (15.47%). METHODS:A risk map was developed and geographic risk factors identified using a B...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-120
更新日期:2010-05-09 00:00:00
abstract:BACKGROUND:The impact of sulfadoxine-pyrimethamine (SP) used as intermittent preventive treatment during pregnancy (IPTp-SP) on mutant parasite selection has been poorly documented in Burkina Faso. This study sought first to explore the relationship between IPTp-SP and the presence of mutant parasites. Second, to asses...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1695-1
更新日期:2017-01-23 00:00:00
abstract:BACKGROUND:Malaria continues to be a major public health problem in remote forested areas in Cambodia. As a national strategy to strengthen community-based malaria control, the Cambodian government has been running the Village Malaria Worker (VMW) project since 2001. This study sought to examine the nature and quality ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-109
更新日期:2010-04-23 00:00:00
abstract:BACKGROUND:Artemisinin-based combination therapy (ACT) has been adopted by the World Health Organization as a first-line treatment for uncomplicated Plasmodium falciparum malaria. In endemic regions, it has proven more effective in treating the disease, and even in reducing its transmission. Nonetheless, there is a sca...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1408-1
更新日期:2016-07-02 00:00:00
abstract::India has committed to eliminate malaria by 2030. The national framework for malaria elimination released by the Government of India plans to achieve this goal through strategic planning in a phased manner. Since vector control is a major component of disease management and vector elimination, it requires a thorough u...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/s12936-019-3011-8
更新日期:2019-12-03 00:00:00
abstract:BACKGROUND:Drug and multidrug-resistant Plasmodium falciparum malaria has existed in Thailand for several decades. Furthermore, Thailand serves as a sentinel for drug-resistant malaria within the Greater Mekong sub-region. However, the drug resistance situation is highly dynamic, changing quickly over time. Here parasi...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-290
更新日期:2012-08-21 00:00:00
abstract:BACKGROUND:Malaria antibody responses measured at delivery have been associated with protection from maternal anaemia and low birth weight deliveries. Whether malarial antibodies present in the first half of pregnancy may protect from these or other poor birth outcomes is unclear. To determine whether malaria antibodie...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1597-7
更新日期:2016-11-09 00:00:00
abstract:BACKGROUND:Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials. However, Plasmodium falciparum parasites with a deletion of the hrp2 gene yield false-negative RDTs and there are concerns the sensitivity of HRP2-ba...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1768-1
更新日期:2017-03-20 00:00:00
abstract:BACKGROUND:Malaria is a major public health issue in Burundi in terms of both morbidity and mortality, with around 2.5 million clinical cases and more than 15,000 deaths each year. It is still the single main cause of mortality in pregnant women and children below five years of age. Because of the severe health and eco...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-10-234
更新日期:2011-08-11 00:00:00
abstract:BACKGROUND:Malaria is an increasing concern in Indonesia. Socio-demographic factors were found to strongly influence malaria prevalence. This research aimed to explore the associations between socio-demographic factors and malaria prevalence in Indonesia. METHODS:The study used a cross-sectional design and analysed re...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-2760-8
更新日期:2019-04-12 00:00:00
abstract:BACKGROUND:Malaria transmission is complex and is believed to be associated with local climate changes. However, simple attempts to extrapolate malaria incidence rates from averaged regional meteorological conditions have proven unsuccessful. Therefore, the objective of this study was to determine if variations in spec...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-166
更新日期:2010-06-16 00:00:00
abstract:BACKGROUND:Adequate malaria diagnosis and treatment remain major difficulties in rural sub-Saharan Africa. These issues deserve renewed attention in the light of first-line treatment with expensive artemisinin-combination therapy (ACT) and changing patterns of transmission intensity. This study describes diagnostic and...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-7-232
更新日期:2008-11-05 00:00:00
abstract:BACKGROUND:Plasmodium knowlesi is the fifth Plasmodium species that can infect humans. The Plasmodium merozoite surface protein-1(42) (MSP-1(42)) is a potential candidate for malaria vaccine. However, limited studies have focused on P. knowlesi MSP-1(42). METHODS:A ~42 kDa recombinant P. knowlesi MSP-1(42) (pkMSP-1(42...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-454
更新日期:2013-12-19 00:00:00
abstract:BACKGROUND:Rosette-formation of Plasmodium falciparum parasitized erythrocytes is of importance in the development of severe malaria. The parasite-derived molecule PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1), central to rosetting, is suggested to be included in a multimeric vaccine targeting severe di...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-32
更新日期:2013-01-24 00:00:00
abstract:BACKGROUND:Diagnosis of Plasmodium falciparum is often based on detection of histidine-rich protein 2 (HRP2) in blood. Most HRP2-based assays have high sensitivity and specificity; however, authors have suggested that antibodies (Ab) to HRP2 could reduce assay sensitivity. This study sought to characterize the antibody...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1704-4
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:The erythrocytic stage of Plasmodium falciparum parasites in humans is clinically important, as the parasites at this growth stage causes malarial symptoms. Most of the currently available anti-malarial drugs target this stage, but the emergence and spread of parasites resistant to anti-malarial drugs are a ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-2642-0
更新日期:2019-01-14 00:00:00
abstract::An improved methodology is presented here for transgenic Plasmodium berghei lines that express the negative selectable marker yFCU (a bifunctional protein that combines yeast cytosine deaminase and uridyl phosphoribosyl transferase (UPRT)) and substitutes delivery of selection drug 5-fluorocytosine (5FC) by intraperit...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-103
更新日期:2012-03-31 00:00:00
abstract:BACKGROUND:The merozoite surface protein 1 (msp1) is one of the most studied vaccine candidate genes in mammalian Plasmodium spp. to have been used for investigations of epidemiology, population structures, and immunity to infections. However methodological difficulties have impeded the use of nuclear markers such as m...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-381
更新日期:2013-10-30 00:00:00
abstract:BACKGROUND:Mass distribution campaigns of insecticide-treated nets for malaria prevention are usually accompanied by intensive behaviour change communication (BCC) to encourage hanging and use of nets. However, data on the effectiveness of these communication efforts are scarce. In preparation for the next round of mas...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1463-7
更新日期:2016-08-19 00:00:00
abstract:BACKGROUND:Conventional diagnosis of malaria has relied upon either clinical diagnosis or microscopic examination of peripheral blood smears. These methods, if not carried out exactly, easily result in the over- or under-diagnosis of malaria. The reliability and accuracy of malaria RDTs, even in extremely challenging h...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-502
更新日期:2014-12-17 00:00:00
abstract:BACKGROUND:Within the context of increasing antimalarial costs and or decreasing malaria transmission, the importance of limiting antimalarial treatment to only those confirmed as having malaria parasites becomes paramount. This motivates for this assessment of the cost-effectiveness of routine use of rapid diagnostic ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-7-176
更新日期:2008-09-15 00:00:00
abstract::The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these can be overcome and...
journal_title:Malaria journal
pub_type:
doi:10.1186/s12936-018-2380-8
更新日期:2018-06-20 00:00:00