Characterization and monitoring of deltamethrin-resistance in Anopheles culicifacies in the presence of a long-lasting insecticide-treated net intervention.

Abstract:

BACKGROUND:Deltamethrin-impregnated, long-lasting insecticidal nets (LLINs) were distributed in the study area from November 2014 to January 2015 to evaluate their impact on malaria transmission in the presence of insecticide-resistant vectors. Studies were carried out in 16 selected clusters in Keshkal sub-district, Chhattisgarh State, India to monitor and characterize deltamethrin resistance in Anopheles culicifacies sensu lato. RESULTS:Deltamethrin susceptibility of An. culicifacies decreased in a post-LLIN survey compared to a pre-LLIN survey and was not significant (p > 0.05) while, the knockdown values showed significant increase (p < 0.05). Pre-exposure to piperonyl butoxide, triphenyl phosphate showed synergism against deltamethrin (p < 0.001). Biochemical assays showed significantly (p < 0.05) elevated monooxygenases in 3 of 5 clusters in post-LLIN survey-I that increased to 10 of 11 clusters in post-LLIN survey-II, while esterases were found significantly elevated in all clusters and both enzymes were involved in conferring pyrethroid resistance, not discounting the involvement of kdr (L1014L/S) gene that was heterozygous and at low frequency (4-5%). CONCLUSION:This field study, in a tribal district of India, after distribution of deltamethrin-impregnated LLINs showed decrease in deltamethrin susceptibility in An. culicifacies, a major vector of malaria in this study area and in India. Results indicated development of resistance as imminent with the increase in insecticide selection pressure. There is an urgent need to develop new vector control tools, with insecticide classes having novel mechanisms of resistance, to avoid or delay the onset of resistance. Regular insecticide resistance monitoring and mechanistic studies should be the priority for the malaria control programmes to suggest strategies for insecticide resistance management. The global commitment to eliminate malaria by 2030 needs various efforts that include development of combination vector control products and interventions and few are becoming available.

journal_name

Malar J

journal_title

Malaria journal

authors

Kona MP,Kamaraju R,Donnelly MJ,Bhatt RM,Nanda N,Chourasia MK,Swain DK,Suman S,Uragayala S,Kleinschmidt I,Pandey V

doi

10.1186/s12936-018-2557-1

subject

Has Abstract

pub_date

2018-11-08 00:00:00

pages

414

issue

1

issn

1475-2875

pii

10.1186/s12936-018-2557-1

journal_volume

17

pub_type

杂志文章
  • Acceptability of insecticide-treated clothing for malaria prevention among migrant rubber tappers in Myanmar: a cluster-randomized non-inferiority crossover trial.

    abstract:BACKGROUND:Insecticide-treated clothing (ITC) has long been used for military and outdoor recreational purposes and there is substantial evidence to show that it can protect against arthropod biting. As a complementary vector control measure, ITC could be used to address outdoor transmission of malaria, particularly am...

    journal_title:Malaria journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12936-017-1737-8

    authors: Crawshaw AF,Maung TM,Shafique M,Sint N,Nicholas S,Li MS,Roca-Feltrer A,Hii J

    更新日期:2017-02-28 00:00:00

  • Five years of malaria control in the continental region, Equatorial Guinea.

    abstract:BACKGROUND:A successful malaria control programme began in 2004 on Bioko Island, Equatorial Guinea. From 2007, the same multiple malaria interventions, though reduced in scope for funding reasons, were introduced to the four mainland provinces of Equatorial Guinea (the continental region) aiming to recreate Bioko's suc...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-12-154

    authors: Rehman AM,Mann AG,Schwabe C,Reddy MR,Roncon Gomes I,Slotman MA,Yellott L,Matias A,Caccone A,Nseng Nchama G,Kleinschmidt I

    更新日期:2013-05-07 00:00:00

  • Extremely low Plasmodium prevalence in wild plovers and coursers from Cape Verde and Madagascar.

    abstract:BACKGROUND:Relatively little is known about the prevalence of blood parasites in shorebirds, especially those breeding in the tropics. The prevalence of blood parasites of the genera Plasmodium, Haemoproteus and Leucocytozoon was assessed in blood samples from Kentish plovers and cream-coloured coursers in Cape Verde, ...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-017-1892-y

    authors: Martínez-de la Puente J,Eberhart-Phillips LJ,Cristina Carmona-Isunza M,Zefania S,Navarro MJ,Kruger O,Hoffman JI,Székely T,Figuerola J

    更新日期:2017-06-08 00:00:00

  • A stakeholder workshop about modelled maps of key malaria indicator survey indicators in Madagascar.

    abstract::The Demographic and Health Surveys (DHS) Program has supported three household Malaria Indicator Surveys (MIS) in Madagascar. The results of 13 key malaria indicators from these surveys have been mapped as continuous surfaces using model-based geostatistical methods. The opportunities and limitations of these mapped o...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-019-2729-7

    authors: Howes RE,Hawa K,Andriamamonjy VF,Franchard T,Miarimbola R,Mioramalala SA,Rafamatanantsoa JF,Rahantamalala MAM,Rajaobary SH,Rajaonera HDG,Rakotonindrainy AP,Rakotoson Andrianjatonavalona C,Randriamiarinjatovo DNAL,Randrianasolo

    更新日期:2019-03-22 00:00:00

  • Intradermal immunization of mice with radiation-attenuated sporozoites of Plasmodium yoelii induces effective protective immunity.

    abstract:BACKGROUND:Intravenous injection of mice with attenuated Plasmodium berghei sporozoites induces sterile immunity to challenge with viable sporozoites. Non-intravenous routes have been reported to yield poor immunity. Because intravenous immunization has been considered to be unacceptable for large scale vaccination of ...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-9-362

    authors: Voza T,Kebaier C,Vanderberg JP

    更新日期:2010-12-15 00:00:00

  • Comparing ownership and use of bed nets at two sites with differential malaria transmission in western Kenya.

    abstract:BACKGROUND:Challenges persist in ensuring access to and optimal use of long-lasting, insecticidal bed nets (LLINs). Factors associated with ownership and use may differ depending on the history of malaria and prevention control efforts in a specific region. Understanding how the cultural and social-environmental contex...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-016-1262-1

    authors: Ernst KC,Hayden MH,Olsen H,Cavanaugh JL,Ruberto I,Agawo M,Munga S

    更新日期:2016-04-14 00:00:00

  • Impact of a behaviour change communication programme on net durability in eastern Uganda.

    abstract:BACKGROUND:The importance of net durability and the average useful life of a net is increasingly recognized as one of the critical factors that determine how often nets need to be replaced. A study to assess the effect of a net care and repair behaviour change communication (BCC) programme on net durability was conduct...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-015-0899-5

    authors: Helinski MH,Namara G,Koenker H,Kilian A,Hunter G,Acosta A,Scandurra L,Selby RA,Mulondo K,Fotheringham M,Lynch M

    更新日期:2015-09-22 00:00:00

  • Plasmodium vivax malaria incidence over time and its association with temperature and rainfall in four counties of Yunnan Province, China.

    abstract:BACKGROUND:Transmission of Plasmodium vivax malaria is dependent on vector availability, biting rates and parasite development. In turn, each of these is influenced by climatic conditions. Correlations have previously been detected between seasonal rainfall, temperature and malaria incidence patterns in various setting...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-12-452

    authors: Wardrop NA,Barnett AG,Atkinson JA,Clements AC

    更新日期:2013-12-18 00:00:00

  • The contribution of agricultural insecticide use to increasing insecticide resistance in African malaria vectors.

    abstract::The fight against malaria is increasingly threatened by failures in vector control due to growing insecticide resistance. This review examines the recent primary research that addresses the putative relationship between agricultural insecticide use and trends in insecticide resistance. To do so, descriptive evidence o...

    journal_title:Malaria journal

    pub_type: 杂志文章,评审

    doi:10.1186/s12936-016-1162-4

    authors: Reid MC,McKenzie FE

    更新日期:2016-02-19 00:00:00

  • The diagnostic accuracy of the hand-held Raman spectrometer for the identification of anti-malarial drugs.

    abstract:BACKGROUND:There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to determine the diagnostic accuracy of the NanoRam(®), a handheld Raman spectrometer (RS), to identify anti-malarial drugs. METHODS:In total, 289 anti-malarial d...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-016-1212-y

    authors: Visser BJ,de Vries SG,Bache EB,Meerveld-Gerrits J,Kroon D,Boersma J,Agnandji ST,van Vugt M,Grobusch MP

    更新日期:2016-03-15 00:00:00

  • Assessment of the utility of a symptom-based algorithm for identifying febrile patients for malaria diagnostic testing in Senegal.

    abstract:BACKGROUND:Malaria rapid diagnostic tests (RDTs) enable point-of-care testing to be nearly as sensitive and specific as reference microscopy. The Senegal National Malaria Control Programme introduced RDTs in 2007, along with a case management algorithm for uncomplicated febrile illness, in which the first step stipulat...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-017-1750-y

    authors: Thwing J,Ba F,Diaby A,Diedhiou Y,Sylla A,Sall G,Diouf MB,Gueye AB,Gaye S,Ndiop M,Cisse M,Ndiaye D,Ba M

    更新日期:2017-03-01 00:00:00

  • Expanding malaria diagnosis and treatment in Lao PDR: lessons learned from a public-private mix initiative.

    abstract:BACKGROUND:As in other countries of the Greater Mekong Sub-region (GMS), the private health sector constitutes a significant avenue where malaria services are provided and presents a unique opportunity for public-private collaboration. In September 2008, a public-private mix (PPM) strategy was launched initially in fou...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-017-2104-5

    authors: Simmalavong N,Phommixay S,Kongmanivong P,Sichanthongthip O,Hongvangthong B,Gopinath D,Sintasath DM

    更新日期:2017-11-13 00:00:00

  • Testing possible causes of gametocyte reduction in temporally out-of-synch malaria infections.

    abstract:BACKGROUND:The intraerythrocytic development cycle (IDC) of the rodent malaria Plasmodium chabaudi is coordinated with host circadian rhythms. When this coordination is disrupted, parasites suffer a 50% reduction in both asexual stages and sexual stage gametocytes over the acute phase of infection. Reduced gametocyte d...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-020-3107-1

    authors: Westwood ML,O'Donnell AJ,Schneider P,Albery GF,Prior KF,Reece SE

    更新日期:2020-01-14 00:00:00

  • How many mosquito nets are needed to achieve universal coverage? Recommendations for the quantification and allocation of long-lasting insecticidal nets for mass campaigns.

    abstract:BACKGROUND:Long-lasting insecticidal nets are an effective tool for malaria prevention, and "universal coverage" with such nets is increasingly the goal of national malaria control programmes. However, national level campaigns in several countries have run out of nets in the course of distribution, indicating a problem...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-9-330

    authors: Kilian A,Boulay M,Koenker H,Lynch M

    更新日期:2010-11-18 00:00:00

  • Analysis of antibody induction upon immunization with distinct NTS-DBL1α-domains of PfEMP1 from rosetting Plasmodium falciparum parasites.

    abstract:BACKGROUND:Rosette-formation of Plasmodium falciparum parasitized erythrocytes is of importance in the development of severe malaria. The parasite-derived molecule PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1), central to rosetting, is suggested to be included in a multimeric vaccine targeting severe di...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-12-32

    authors: Angeletti D,Albrecht L,Wahlgren M,Moll K

    更新日期:2013-01-24 00:00:00

  • Active case detection, treatment of falciparum malaria with combined chloroquine and sulphadoxine/pyrimethamine and vivax malaria with chloroquine and molecular markers of anti-malarial resistance in the Republic of Vanuatu.

    abstract:BACKGROUND:Chloroquine-resistant Plasmodium falciparum was first described in the Republic of Vanuatu in the early 1980s. In 1991, the Vanuatu Ministry of Health instituted new treatment guidelines for uncomplicated P. falciparum infection consisting of chloroquine/sulphadoxine-pyrimethamine combination therapy. Chloro...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-9-89

    authors: Kinzer MH,Chand K,Basri H,Lederman ER,Susanti AI,Elyazar I,Taleo G,Rogers WO,Bangs MJ,Maguire JD

    更新日期:2010-04-06 00:00:00

  • Battling the malaria iceberg with chloroquine in India.

    abstract::The National Vector Borne Disease Control Programme (NVBDCP) of the Ministry of Health, Government of India is reporting about 2 million parasite positive cases each year, although case incidence is 30-fold or more under-estimated. Forty five to fifty percent of Plasmodium infections are caused by Plasmodium falciparu...

    journal_title:Malaria journal

    pub_type: 社论

    doi:10.1186/1475-2875-6-105

    authors: Sharma VP

    更新日期:2007-08-07 00:00:00

  • Assessment of molecular markers for anti-malarial drug resistance after the introduction and scale-up of malaria control interventions in western Kenya.

    abstract:BACKGROUND:Although it is well known that drug pressure selects for drug-resistant parasites, the role of transmission reduction by insecticide-treated bed nets (ITNs) on drug resistance remains unclear. In this study, the drug resistance profile of current and previous first-line anti-malarials in Kenya was assessed w...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-015-0588-4

    authors: Shah M,Omosun Y,Lal A,Odero C,Gatei W,Otieno K,Gimnig JE,ter Kuile F,Hawley WA,Nahlen B,Kariuki S,Walker E,Slutsker L,Hamel M,Shi YP

    更新日期:2015-02-14 00:00:00

  • Should countries implementing an artemisinin-based combination malaria treatment policy also introduce rapid diagnostic tests?

    abstract:BACKGROUND:Within the context of increasing antimalarial costs and or decreasing malaria transmission, the importance of limiting antimalarial treatment to only those confirmed as having malaria parasites becomes paramount. This motivates for this assessment of the cost-effectiveness of routine use of rapid diagnostic ...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-7-176

    authors: Zikusooka CM,McIntyre D,Barnes KI

    更新日期:2008-09-15 00:00:00

  • Treatment choices for fevers in children under-five years in a rural Ghanaian district.

    abstract:BACKGROUND:Health care demand studies help to examine the behaviour of individuals and households during illnesses. Few of existing health care demand studies examine the choice of treatment services for childhood illnesses. Besides, in their analyses, many of the existing studies compare alternative treatment options ...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-9-188

    authors: Nonvignon J,Aikins MK,Chinbuah MA,Abbey M,Gyapong M,Garshong BN,Fia S,Gyapong JO

    更新日期:2010-06-28 00:00:00

  • Assessment of the effectiveness of the CD3+ tool to detect counterfeit and substandard anti-malarials.

    abstract:BACKGROUND:The US FDA recently developed CD3+, a counterfeit detection tool that is based on sample illumination at specific wavelengths of light and visual comparison of suspect sample and packaging materials to an authentic sample. To test performance of the CD3+ in field conditions, a study was conducted in Ghana wh...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-016-1180-2

    authors: Batson JS,Bempong DK,Lukulay PH,Ranieri N,Satzger RD,Verbois L

    更新日期:2016-02-25 00:00:00

  • Human population movement and behavioural patterns in malaria hotspots on the Thai-Myanmar border: implications for malaria elimination.

    abstract:BACKGROUND:Malaria is heterogeneously distributed across landscapes. Human population movement (HPM) could link sub-regions with varying levels of transmission, leading to the persistence of disease even in very low transmission settings. Malaria along the Thai-Myanmar border has been decreasing, but remains heterogene...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-019-2704-3

    authors: Saita S,Pan-Ngum W,Phuanukoonnon S,Sriwichai P,Silawan T,White LJ,Parker DM

    更新日期:2019-03-08 00:00:00

  • Immunogenicity analysis of conserved fragments in Plasmodium ovale species merozoite surface protein 4.

    abstract:BACKGROUND:There is an urgent need for an effective vaccine to control and eradicate malaria, one of the most serious global infectious diseases. Plasmodium merozoite surface protein 4 (MSP4) has been listed as a blood-stage subunit vaccine candidate for malaria. Infection with Plasmodium ovale species including P. ova...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-020-03207-7

    authors: Uwase J,Chu R,Kassegne K,Lei Y,Shen F,Fu H,Sun Y,Xuan Y,Cao J,Cheng Y

    更新日期:2020-03-30 00:00:00

  • Molecular surveillance of the Pfmdr1 N86Y allele among Congolese pregnant women with asymptomatic malaria.

    abstract:BACKGROUND:Malaria in pregnancy is associated with considerable morbidity and mortality. Regular surveillance of artemisinin-based combination therapy tolerance, or molecular makers of resistance, is vital for effective malaria treatment, control and eradication programmes. Plasmodium falciparum multiple drug resistanc...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-020-03246-0

    authors: Dossou-Yovo LR,Ntoumi F,Koukouikila-Koussounda F,Vouvoungui JC,Adedoja A,Nderu D,Velavan TP,Lenga A

    更新日期:2020-05-08 00:00:00

  • Strategy to improve malaria surveillance system preventing transfusion-transmitted malaria in blood banks using molecular diagnostic.

    abstract:BACKGROUND:Malaria can be transmitted by blood transfusion through donations collected from asymptomatic or parasitic donors. The parasites are released into the bloodstream during its life cycle and will therefore be present in donated blood by infected individuals. All cases of transfusion-transmitted malaria (TTM) n...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-018-2486-z

    authors: Batista-Dos-Santos SA,Freitas DRC,Raiol M,Cabral GF,Feio AC,Póvoa MM,Cunha MG,Ribeiro-Dos-Santos Â

    更新日期:2018-10-01 00:00:00

  • Describing interaction effect between lagged rainfalls on malaria: an epidemiological study in south-west China.

    abstract:BACKGROUND:When discussing the relationship between meteorological factors and malaria, previous studies mainly focus on the interaction between different climatic factors, while the possible interaction within one particular climatic predictor at different lag periods has been largely neglected. In this study, this is...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-017-1706-2

    authors: Wu Y,Qiao Z,Wang N,Yu H,Feng Z,Li X,Zhao X

    更新日期:2017-01-31 00:00:00

  • High-resolution metabolomics to discover potential parasite-specific biomarkers in a Plasmodium falciparum erythrocytic stage culture system.

    abstract:BACKGROUND:Current available malaria diagnostic methods each have some limitations to meet the need for real-time and large-scale screening of asymptomatic and low density malaria infection at community level. It was proposed that malaria parasite-specific low molecular-weight metabolites could be used as biomarkers fo...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-015-0651-1

    authors: Park YH,Shi YP,Liang B,Medriano CA,Jeon YH,Torres E,Uppal K,Slutsker L,Jones DP

    更新日期:2015-03-24 00:00:00

  • Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children.

    abstract:BACKGROUND:Drug resistance in Plasmodium falciparum is common in many endemic and other settings but there is no clear recommendation on when to change therapy when there is delay in parasite clearance after initiation of therapy in African children. METHODS:The factors contributing to delay in parasite clearance, def...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/1475-2875-9-53

    authors: Sowunmi A,Adewoye EO,Gbotsho GO,Happi CT,Sijuade A,Folarin OA,Okuboyejo TM,Michael OS

    更新日期:2010-02-15 00:00:00

  • Evaluation of the behaviour change communication and community mobilization activities in Myanmar artemisinin resistance containment zones.

    abstract:BACKGROUND:Behaviour change communication (BCC) can improve malaria prevention and treatment behaviour. As a one of the activities under Myanmar Artemisinin Resistance Containment (MARC) programme, BCC have been conducting. This study aimed to evaluate the effectiveness of the behaviour change communication and communi...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-015-1047-y

    authors: Nyunt MH,Aye KM,Kyaw MP,Wai KT,Oo T,Than A,Oo HW,Phway HP,Han SS,Htun T,San KK

    更新日期:2015-12-23 00:00:00

  • Systematic review of analytical methods applied to longitudinal studies of malaria.

    abstract:BACKGROUND:Modelling risk of malaria in longitudinal studies is common, because individuals are at risk for repeated infections over time. Malaria infections result in acquired immunity to clinical malaria disease. Prospective cohorts are an ideal design to relate the historical exposure to infection and development of...

    journal_title:Malaria journal

    pub_type: 杂志文章

    doi:10.1186/s12936-019-2885-9

    authors: Stanley CC,Kazembe LN,Mukaka M,Otwombe KN,Buchwald AG,Hudgens MG,Mathanga DP,Laufer MK,Chirwa TF

    更新日期:2019-07-29 00:00:00