Abstract:
BACKGROUND:Transmission of Plasmodium vivax malaria is dependent on vector availability, biting rates and parasite development. In turn, each of these is influenced by climatic conditions. Correlations have previously been detected between seasonal rainfall, temperature and malaria incidence patterns in various settings. An understanding of seasonal patterns of malaria, and their weather drivers, can provide vital information for control and elimination activities. This research aimed to describe temporal patterns in malaria, rainfall and temperature, and to examine the relationships between these variables within four counties of Yunnan Province, China. METHODS:Plasmodium vivax malaria surveillance data (1991-2006), and average monthly temperature and rainfall were acquired. Seasonal trend decomposition was used to examine secular trends and seasonal patterns in malaria. Distributed lag non-linear models were used to estimate the weather drivers of malaria seasonality, including the lag periods between weather conditions and malaria incidence. RESULTS:There was a declining trend in malaria incidence in all four counties. Increasing temperature resulted in increased malaria risk in all four areas and increasing rainfall resulted in increased malaria risk in one area and decreased malaria risk in one area. The lag times for these associations varied between areas. CONCLUSIONS:The differences detected between the four counties highlight the need for local understanding of seasonal patterns of malaria and its climatic drivers.
journal_name
Malar Jjournal_title
Malaria journalauthors
Wardrop NA,Barnett AG,Atkinson JA,Clements ACdoi
10.1186/1475-2875-12-452subject
Has Abstractpub_date
2013-12-18 00:00:00pages
452issn
1475-2875pii
1475-2875-12-452journal_volume
12pub_type
杂志文章相关文献
MALARIA JOURNAL文献大全abstract:BACKGROUND:Drug resistance in Plasmodium falciparum is common in many endemic and other settings but there is no clear recommendation on when to change therapy when there is delay in parasite clearance after initiation of therapy in African children. METHODS:The factors contributing to delay in parasite clearance, def...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-53
更新日期:2010-02-15 00:00:00
abstract:BACKGROUND:The north coast of Guadalcanal has some of the most intense malaria transmission in the Solomon Islands. And, there is a push for intensified vector control in Guadalcanal, to improve the livelihood of residents and to minimize the number of cases, which are regularly exported to the rest of the country. The...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-56
更新日期:2014-02-15 00:00:00
abstract:BACKGROUND:As a result of the reintroduction of malaria in the Republic of Korea (ROK) in 1993 and the threat to military and civilian populations, the Korea Military National Defense (MND) increased emphasis on vector control in 2012 at ROK Army (ROKA) installations located near the DMZ, while decreasing chemoprophyla...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1301-y
更新日期:2016-05-05 00:00:00
abstract:INTRODUCTION:Malaria is the largest cause of health services attendance, hospital admissions and child deaths in Tanzania. At the Abuja Summit in April 2000 Tanzania committed itself to protect 60% of its population at high risk of malaria by 2005. The country is, therefore, determined to ensure that sustainable malari...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-4-34
更新日期:2005-07-22 00:00:00
abstract:BACKGROUND:Malaria vector control in Tanzania is based on use of long-lasting insecticide treated nets (LLINs) and indoor residual spraying (IRS), which both rely on the use of chemical insecticides. The effectiveness of these control tools is endangered by the development of insecticide resistance in the major malaria...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-2087-2
更新日期:2017-10-30 00:00:00
abstract::BACKGROUND: This study investigated causes of malaria and how cases were managed at household level, in order to improve the ability to identify malaria and ensure correct use of chloroquine. It was conducted in Nakonde District, Northern Province of Zambia, between 2000 and 2001. Nakonde district is in a hyperendemic...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-2-43
更新日期:2003-11-19 00:00:00
abstract:BACKGROUND:Although chemoprophylaxis remains an important strategy for preventing malaria in travellers, its effectiveness may be compromised by lack of adherence. Inappropriate use of chemoprophylaxis is likely to increase the risk of acquiring malaria, but may probably also worsen the severity of imported cases. The ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-265
更新日期:2013-07-31 00:00:00
abstract::Malaria currently causes more harm to human beings than any other parasitic disease, and disproportionally affects low-income populations. The ethical issues raised by efforts to control or eliminate malaria have received little explicit analysis, in comparison with other major diseases of poverty. While some ethical ...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/s12936-015-1042-3
更新日期:2015-12-22 00:00:00
abstract:BACKGROUND:Data collected in clinical trials have been used to develop scoring systems that identify adults with malaria at greatest risk of death. One of these, the RCAM score, can be simply determined by measuring a patient's Glasgow Coma Score and respiratory rate on admission to hospital. However the safety of usin...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0549-y
更新日期:2015-02-07 00:00:00
abstract::An improved methodology is presented here for transgenic Plasmodium berghei lines that express the negative selectable marker yFCU (a bifunctional protein that combines yeast cytosine deaminase and uridyl phosphoribosyl transferase (UPRT)) and substitutes delivery of selection drug 5-fluorocytosine (5FC) by intraperit...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-103
更新日期:2012-03-31 00:00:00
abstract:BACKGROUND:The pro-inflammatory S100 calcium binding protein A8 (S100A8) is elevated in the serum of patients with Plasmodium falciparum malaria, but its function in Plasmodium vivax malaria is not yet clear. This function was investigated in P. vivax-infected patients in this study. METHODS:The level of S100A8 in the...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0855-4
更新日期:2015-10-05 00:00:00
abstract:BACKGROUND:Nicotinamide adenine dinucleotide (NAD+) is an essential molecule in the energy metabolism of living beings, and it has various cellular functions. The main enzyme in the biosynthesis of this nucleotide is nicotinamide/nicotinate mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1/18) because it is the con...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2307-4
更新日期:2018-04-11 00:00:00
abstract:BACKGROUND:In the Tanga District of coastal Tanzania, malaria is one of the primary causes of mortality for children under the age of five. While some children are treated with malaria medications in biomedical facilities, as the World Health Organization recommends, others receive home-care or treatment from tradition...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-8-240
更新日期:2009-10-27 00:00:00
abstract:BACKGROUND:Fixed-dose combination antimalarial drugs have played an increasingly important role in the treatment and chemoprophylaxis of falciparum malaria since the worldwide failure of monotherapy with chloroquine. Atovaquone-proguanil is one such combination drug used both for prophylaxis in travellers, and for trea...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-7-240
更新日期:2008-11-20 00:00:00
abstract:BACKGROUND:While sub-microscopic malarial infections are frequent and potentially deleterious during pregnancy, routine molecular detection is still not feasible. This study aimed to assess the performance of a Histidine Rich Protein 2 (HRP2)-based ultrasensitive rapid diagnostic test (uRDT, Alere Malaria Ag Pf) for th...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-020-03261-1
更新日期:2020-05-24 00:00:00
abstract:BACKGROUND:Due to the development of resistance to synthetic insecticides, adverse effects to human health, non-target organisms and the environment, there is an urgent need to develop new insecticides, which are effective, safe, biodegrable and target-specific. This study was undertaken to evaluate the adulticidal act...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-173
更新日期:2014-05-06 00:00:00
abstract::The Rethinking Malaria Leadership Forum, held at Harvard Business School in February 2017 with collaboration of the Barcelona Institute for Global Health and the Swiss Tropical and Public Health Institute, identified this training gap as a high priority for both analysis and action. The gap in human resource training ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2199-3
更新日期:2018-01-25 00:00:00
abstract:BACKGROUND:Insecticide-treated nets (ITNs) and house modifications are proven vector control tools, yet in most regions, full coverage has not been achieved. This study investigates household factors associated with access to ITNs and house modification in Tanzania. METHODS:Baseline cross-sectional survey data from pr...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-020-03303-8
更新日期:2020-06-23 00:00:00
abstract:BACKGROUND:Health care demand studies help to examine the behaviour of individuals and households during illnesses. Few of existing health care demand studies examine the choice of treatment services for childhood illnesses. Besides, in their analyses, many of the existing studies compare alternative treatment options ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-188
更新日期:2010-06-28 00:00:00
abstract:BACKGROUND:In clinical trials of therapy for uncomplicated Plasmodium falciparum, there are usually some patients who fail treatment even in the absence of drug resistance. Treatment failures, which can be due to recrudescence or re-infection, are categorized as 'clinical' or 'parasitological' failures, the former indi...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-020-03520-1
更新日期:2020-12-09 00:00:00
abstract:BACKGROUND:Successful reduction of malaria transmission to very low levels has made Isabel Province, Solomon Islands, a target for early elimination by 2014. High malaria transmission in neighbouring provinces and the potential for local asymptomatic infections to cause malaria resurgence highlights the need for sub-na...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-101
更新日期:2012-03-30 00:00:00
abstract:BACKGROUND:Conventional diagnosis of malaria has relied upon either clinical diagnosis or microscopic examination of peripheral blood smears. These methods, if not carried out exactly, easily result in the over- or under-diagnosis of malaria. The reliability and accuracy of malaria RDTs, even in extremely challenging h...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-502
更新日期:2014-12-17 00:00:00
abstract:BACKGROUND:Between 2007 and 2013, the Tanzanian public sector received 93.1 million doses of first-line anti-malarial artemisinin-based combination therapy (ACT) in the form of artemether-lumefantrine entirely supplied by funding partners. The introduction of a health facility ACT stock monitoring system using SMS tech...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-181
更新日期:2014-05-11 00:00:00
abstract:BACKGROUND:There is growing concern that malaria vector resistance to pyrethroid insecticides may reduce the effectiveness of long-lasting insecticidal nets (LLINs). Combination LLINs are designed to control susceptible and pyrethroid-resistant mosquito populations through a mixture of pyrethroid with piperonyl butoxid...
journal_title:Malaria journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12936-017-2124-1
更新日期:2017-11-21 00:00:00
abstract:BACKGROUND:Clinical profiling of two components for a synthetic peptide-based virosomal malaria vaccine has yielded promising results, encouraging the search for additional components for inclusion in a final multi-valent vaccine formulation. This report describes the immunological characterization of linear and cycliz...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-8-314
更新日期:2009-12-30 00:00:00
abstract:BACKGROUND:Malaria is a widespread infectious disease that threatens a large proportion of the population in tropical and subtropical areas. Given the emerging resistance against the current standard anti-malaria chemotherapeutics, the development of alternative drugs is urgently needed. New anti-malarials representing...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1839-3
更新日期:2017-05-15 00:00:00
abstract:BACKGROUND:Previous efforts to eradicate malaria parasites, particularly Plasmodium falciparum, have failed in part due to the emergence of drug resistant parasites and mosquitoes resistant to insecticides. Using an artemisinin-based combination therapy (ACT) that kills parasites quickly, a strategy was designed to eli...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-57
更新日期:2010-02-23 00:00:00
abstract:BACKGROUND:There is evidence that suggests that undernutrition has a detrimental effect on malarial immunity in children. The aim of the study was to discover whether nutrient supplementation improved development of malarial antibody immunity in children up to 18 months of age. METHODS:The study was conducted with a s...
journal_title:Malaria journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12936-018-2224-6
更新日期:2018-02-07 00:00:00
abstract:BACKGROUND:The recent reports on the decreasing susceptibility of Plasmodium falciparum to artemisinin derivatives along the Thailand and Myanmar border are worrying. Indeed it may spread to India and then Africa, repeating the same pattern observed for chloroquine resistance. Therefore, it is essential to start monito...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-207
更新日期:2014-05-31 00:00:00
abstract:BACKGROUND:The emergence of Plasmodium falciparum resistance to artemisinins threatens to undermine the effectiveness of artemisinin-based combination anti-malarial therapy. Developing suitable drugs to replace artemisinins requires the identification of new compounds that display rapid parasite killing kinetics. Howev...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0962-2
更新日期:2015-11-05 00:00:00