Abstract:
BACKGROUND:Relatively little is known about the prevalence of blood parasites in shorebirds, especially those breeding in the tropics. The prevalence of blood parasites of the genera Plasmodium, Haemoproteus and Leucocytozoon was assessed in blood samples from Kentish plovers and cream-coloured coursers in Cape Verde, and samples of Kittlitz's plovers, Madagascar plovers and white-fronted plovers in Madagascar. RESULTS:Only two of these samples were positive for Plasmodium: a Kittlitz's plover was infected by a generalist lineage of Plasmodium that has already been reported in Europe and Africa, while in a white-fronted plover direct sequencing revealed a previously un-described Plasmodium lineage. CONCLUSION:Potential explanations for the low prevalence of blood parasites include the scarcity of vectors in habitats used by these bird species and their resistance to parasitic infections.
journal_name
Malar Jjournal_title
Malaria journalauthors
Martínez-de la Puente J,Eberhart-Phillips LJ,Cristina Carmona-Isunza M,Zefania S,Navarro MJ,Kruger O,Hoffman JI,Székely T,Figuerola Jdoi
10.1186/s12936-017-1892-ysubject
Has Abstractpub_date
2017-06-08 00:00:00pages
243issue
1issn
1475-2875pii
10.1186/s12936-017-1892-yjournal_volume
16pub_type
杂志文章相关文献
MALARIA JOURNAL文献大全abstract:BACKGROUND:Sulfadoxine-pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis and is considered for programmes in the Democratic Republic of Congo (DRC). However, SP efficacy is threatened by drug resistance, that is conferred by mutations in the dhfr and dhps genes. The World Health Organization has specified...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-3057-7
更新日期:2019-12-18 00:00:00
abstract:BACKGROUND:Premature death of Plasmodium-infected erythrocytes is considered to favourably influence the clinical course of malaria. Aurothiomalate has previously been shown to trigger erythrocyte death or eryptosis, which is characterized by cell membrane scrambling leading to phosphatidylserine exposure at the cell s...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-118
更新日期:2010-05-07 00:00:00
abstract::The National Vector Borne Disease Control Programme (NVBDCP) of the Ministry of Health, Government of India is reporting about 2 million parasite positive cases each year, although case incidence is 30-fold or more under-estimated. Forty five to fifty percent of Plasmodium infections are caused by Plasmodium falciparu...
journal_title:Malaria journal
pub_type: 社论
doi:10.1186/1475-2875-6-105
更新日期:2007-08-07 00:00:00
abstract:BACKGROUND:In Plasmodium, the high level of genetic diversity and the interactions established by co-infecting parasite populations within the same host may be a source of selection on pathogen virulence and drug resistance. As different patterns have already been described in humans and mosquitoes, parasite diversity ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-114
更新日期:2013-03-27 00:00:00
abstract:BACKGROUND:Donor financing for malaria has declined since 2010 and this trend is projected to continue for the foreseeable future. These reductions have a significant impact on lower burden countries actively pursuing elimination, which are usually a lesser priority for donors. While domestic spending on malaria has be...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1890-0
更新日期:2017-07-14 00:00:00
abstract:BACKGROUND:Developing thermostable vaccines is a challenge for pharmaceutical companies due to the inherent instability of biological molecules in aqueous solution. The problem is even more stringent in regions subjected to high temperatures in which protective cold chain is difficult to maintain due to a lack of infra...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-020-03253-1
更新日期:2020-06-08 00:00:00
abstract:BACKGROUND:Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens play a critical role in host immune evasion. Serologic responses to these antigens have been associated with protection from clinical malaria, suggesting that antibodies to PfEMP1 antigens may contribute to natural immunity. The first N-t...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-2905-9
更新日期:2019-08-13 00:00:00
abstract:BACKGROUND:Over the past several years, thousands of microRNAs (miRNAs) have been identified in the genomes of various insects through cloning and sequencing or even by computational prediction. However, the number of miRNAs identified in anopheline species is low and little is known about their role. The mosquito Anop...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1591-0
更新日期:2016-11-08 00:00:00
abstract:BACKGROUND:Anopheles arabiensis is a dominant vector of malaria in sub-Saharan Africa, which feeds indoors and outdoors on human and other vertebrate hosts, making it a difficult species to control with existing control methods. Novel methods that reduce human-vector interactions are, therefore, required to improve the...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1386-3
更新日期:2016-07-21 00:00:00
abstract:BACKGROUND:Convulsions is one of the key signs of severe malaria among children under five years of age, potentially leading to serious complications or death. Several studies of care-seeking behaviour have revealed that local illness concepts linked to convulsions (referred to as degedege in Tanzanian Kiswahili) calle...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-8-144
更新日期:2009-06-29 00:00:00
abstract:BACKGROUND:Artemisinin-derivative formulations are now widely used to treat falciparum malaria. However, the dry powder suspensions developed for children are few and/or are of poor quality. In addition to the active compound, the presence of a suitable preservative in these medicines is essential. In this study, an ev...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-6-12
更新日期:2007-01-26 00:00:00
abstract:BACKGROUND:The role of the liver for survival of blood-stage malaria is only poorly understood. In experimental blood-stage malaria with Plasmodium chabaudi, protective vaccination induces healing and, thus, survival of otherwise lethal infections. This model is appropriate to study the role of the liver in vaccination...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2366-6
更新日期:2018-05-29 00:00:00
abstract:BACKGROUND:Plasmodium falciparum readily develops resistance to the anti-folates pyrimethamine and proguanil via a characteristic set of mutations in the dihydrofolate reductase (PfDHFR) gene that leads to reduced competitive drug binding at the enzyme's active site. Analogous mutations can be found in the DHFR gene in...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-65
更新日期:2010-03-02 00:00:00
abstract:BACKGROUND:The effects that artemether-lumefantrine (AL) has on gametocyte dynamics in the short-term have recently been described. However there is limited long-term longitudinal data on the effect of AL on gametocyte dynamics in asymptomatic children. METHODS:An epidemiological study was conducted in Kombewa, Wester...
journal_title:Malaria journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2875-13-265
更新日期:2014-07-09 00:00:00
abstract:BACKGROUND:Appropriate case management of suspected malaria in Cambodia is critical given anti-malarial drug resistance in the region. Improving diagnosis and the use of recommended malarial treatments is a challenge in Cambodia where self-treatment and usage of drug cocktails is widespread, a notable difference from m...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-335
更新日期:2012-10-05 00:00:00
abstract:BACKGROUND:Within the context of increasing antimalarial costs and or decreasing malaria transmission, the importance of limiting antimalarial treatment to only those confirmed as having malaria parasites becomes paramount. This motivates for this assessment of the cost-effectiveness of routine use of rapid diagnostic ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-7-176
更新日期:2008-09-15 00:00:00
abstract:BACKGROUND:Plasmodium vivax parasites are the predominant cause of malaria infections in the Brazilian Amazon. Infected individuals are treated with primaquine, which can induce haemolytic anaemia in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals and may lead to severe and fatal complications. This X-li...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1889-6
更新日期:2017-06-15 00:00:00
abstract:BACKGROUND:Pyrethroid-resistant mosquitoes are an increasing threat to malaria vector control. The Global Plan for Insecticide Resistance Management (GPIRM) recommends rotation of non-pyrethroid insecticides for indoor residual spraying (IRS). The options from other classes are limited. The carbamate bendiocarb and the...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-37
更新日期:2014-01-29 00:00:00
abstract:BACKGROUND:Cerebral malaria (CM) is associated with morbidity and mortality despite the use of potent anti-malarial agents. Brain endothelial cell activation and dysfunction from oxidative and inflammatory host responses and products released by Plasmodium falciparum-infected erythrocytes (IE), are likely the major con...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-020-03447-7
更新日期:2020-10-21 00:00:00
abstract:BACKGROUND:The standard in vitro protocol currently in use for drug testing against Plasmodium falciparum, based on the incorporation of the purine [3H]-hypoxanthine, has two serious drawbacks. Firstly it is unsuitable for the testing of drugs that directly or indirectly impact on purine salvage or metabolism. Secondly...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-5-95
更新日期:2006-10-31 00:00:00
abstract:BACKGROUND:A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium falciparum isolates, 11 years after CQ withdrawal in Southeast Nigeria. METHODS:Filter-paper blo...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-2977-6
更新日期:2019-10-07 00:00:00
abstract:BACKGROUND:Sulphadoxine-pyrimethamine (SP) has been in use for the treatment of uncomplicated falciparum malaria in Malaysia since the 1970s and is still widely employed in spite of widespread clinical resistance. Resistance to SP is known to be mediated by mutations in the pfdhfr and pfdhps genes. The aim of the prese...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-198
更新日期:2013-06-12 00:00:00
abstract:BACKGROUND:Sub-Saharan Africa (SSA) has embarked on a new era of dam building to improve food security and promote economic development. Nonetheless, the future impacts of dams on malaria transmission are poorly understood and seldom investigated in the context of climate and demographic change. METHODS:The distributi...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1498-9
更新日期:2016-09-05 00:00:00
abstract:BACKGROUND:T1BT* is a peptide construct containing the T1 and B epitopes located in the 5' minor repeat and the 3' major repeat of the central repeat region of the Plasmodium falciparum circumsporozoite protein (CSP), respectively, and the universal T* epitope located in the C-terminus of the same protein. This peptide...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-104
更新日期:2013-03-18 00:00:00
abstract:BACKGROUND:Over the last decade, the incidence of confirmed malaria has declined significantly in Nepal. The aim of this paper is to assess the spatio-temporal distribution of malaria and its association with climatic factors and vector control interventions in two high-risk districts of Nepal. METHODS:Hotspot analysi...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-457
更新日期:2014-11-25 00:00:00
abstract::Unfortunately after publication of the original article [1], it came to the author's attention that there is an error in the caption of Fig. 2. ...
journal_title:Malaria journal
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12936-018-2429-8
更新日期:2018-08-08 00:00:00
abstract:BACKGROUND:Mosquito transgenesis offers new promises for the genetic control of vector-borne infectious diseases such as malaria and dengue fever. Genetic control strategies require the release of large number of male mosquitoes into field populations, whether they are based on the use of sterile males (sterile insect ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-302
更新日期:2012-08-28 00:00:00
abstract::Plasmodium knowlesi is a potentially life-threatening zoonotic malaria parasite due to its relatively short erythrocytic cycle. Microscopic identification of P. knowlesi is difficult, with "compacted parasite cytoplasm" being one of the important identifying keys. This report is about a case of hyperparasitaemic human...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-88
更新日期:2013-03-06 00:00:00
abstract::Artemisinin, from which the artemether component of Coartem (artemether/lumefantrine, AL) is derived, is obtained from the plant sweet wormwood (Artemisia annua) which has been used for over 2,000 years as a Chinese herbal remedy. Artemisinin was first identified by Chinese researchers as the active anti-malarial cons...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/1475-2875-8-S1-S3
更新日期:2009-10-12 00:00:00
abstract:BACKGROUND:With the increase in use of point-of-care diagnostic tests for malaria and other diseases comes the necessity of storing the diagnostic kits and the drugs required for subsequent management, in remote areas, where temperatures are high and electricity supply is unreliable or unavailable. METHODS:To address ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-31
更新日期:2010-01-23 00:00:00