Hyperparasitaemic human Plasmodium knowlesi infection with atypical morphology in peninsular Malaysia.

abstract：BACKGROUND:Most malaria rapid diagnostic tests (RDTs) detect Plasmodium falciparum and an antigen common to the four species. Plasmodium vivax-specific RDTs target P. vivax-specific parasite lactate dehydrogenase (Pv-pLDH). Previous observations of false positive Pv-pLDH test lines in P. falciparum samples incited to t...

journal_title：Malaria journal

authors： Maltha J,Gillet P,Cnops L,van den Ende J,van Esbroeck M,Jacobs J

更新日期：2010-07-10 00:00:00

abstract：BACKGROUND:In malaria-endemic areas, human populations are frequently exposed to immunomodulatory salivary components injected during mosquito blood feeding. The consequences on pathogen-specific immune responses are not well known. This study evaluated and compared the humoral responses specific to merozoite stage vac...

journal_title：Malaria journal

authors： Aka KG,Traoré DF,Sagna AB,Zoh DD,Assi SB,Tchiekoi BN,Adja AM,Remoue F,Poinsignon A

更新日期：2020-02-21 00:00:00

abstract：BACKGROUND:The ACT recommended by WHO is very effective and well-tolerated. However, these combinations need to be administered for three days, which may limit adherence to treatment.The combination of dihydroartemisinin-piperaquine phosphate-trimethoprim (Artecom®, Odypharm Ltd), which involves treatment over two days...

journal_title：Malaria journal

authors： Menan H,Faye O,Same-Ekobo A,Oga AS,Faye B,Kiki Barro CP,Kuete T,N'diaye JL,Vicky AM,Tine R,Yavo W,Kane D,Kassi KF,Kone M

更新日期：2011-07-08 00:00:00

abstract：BACKGROUND:Plasmodium malariae is the most neglected of the six human malaria species and it is still unknown which is the mechanism underlying the long latency of this Plasmodium. CASE PRESENTATION:A case of PCR-confirmed P. malariae recurrence in a 52-year old Italian man was observed 5 months after a primary attack...

journal_title：Malaria journal

authors： Grande R,Antinori S,Meroni L,Menegon M,Severini C

更新日期：2019-05-14 00:00:00

abstract：BACKGROUND:Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmodium vivax malaria whe...

journal_title：Malaria journal

authors： Njokah MJ,Kang'ethe JN,Kinyua J,Kariuki D,Kimani FT

更新日期：2016-07-22 00:00:00

abstract：BACKGROUND:The study of the Plasmodium falciparum heavy metal transporter gene pfmdr2 employed radioactive labelled heavy metal. As the use of radioactive isotopes shrank considerably during the last few years, resulting in the cessation of the production of some isotopes, amongst them Cadmium109 which was used for tha...

journal_title：Malaria journal

authors： Rosental B,Hadad U,Sinay R,Braiman A,Porgador A,Pollack Y

更新日期：2012-11-08 00:00:00

abstract：BACKGROUND:Environmental temperature is an important driver of malaria transmission dynamics. Both the parasite and vector are sensitive to mean ambient temperatures and daily temperature variation. To understand transmission ecology, therefore, it is important to determine the range of microclimatic temperatures exper...

journal_title：Malaria journal

authors： Cator LJ,Thomas S,Paaijmans KP,Ravishankaran S,Justin JA,Mathai MT,Read AF,Thomas MB,Eapen A

更新日期：2013-03-02 00:00:00

abstract：BACKGROUND:Malaria is a major public health problem in endemic countries including Sudan, where about 75% of populations are at risk. Due to widespread of chloroquine-resistant strains of Plasmodium falciparum, artemisinin-based combination therapy (ACT) is currently treatment of choice for malaria in the vast majority...

journal_title：Malaria journal

authors： Adam I,Ibrahim Y,Gasim GI

更新日期：2018-03-13 00:00:00

abstract：BACKGROUND:Many recent studies have examined the impact of urbanization on Plasmodium falciparum malaria endemicity and found a general trend of reduced transmission in urban areas. However, none has examined the effect of urbanization on Plasmodium vivax malaria, which is the most widely distributed malaria species an...

journal_title：Malaria journal

authors： Qi Q,Guerra CA,Moyes CL,Elyazar IR,Gething PW,Hay SI,Tatem AJ

更新日期：2012-12-05 00:00:00

abstract：BACKGROUND:The number of Plasmodium falciparum malaria cases around the world has decreased substantially over the last 15 years, but with the spread of resistance against anti-malarial drugs and insecticides, this decline may not continue. There is an urgent need to consider alternative, accelerated strategies to elim...

journal_title：Malaria journal

authors： Tun STT,von Seidlein L,Pongvongsa T,Mayxay M,Saralamba S,Kyaw SS,Chanthavilay P,Celhay O,Nguyen TD,Tran TN,Parker DM,Boni MF,Dondorp AM,White LJ

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be expedited. Molecular biology techniques used for monitoring rely on the detection of k13 validated mutants by using PCR and Sanger sequencing approach, usually not ava...

journal_title：Malaria journal

authors： Vachot-Ganée L,Khim N,Iannello A,Legrand E,Kim S,Eam R,Khean C,Ken M,Ashley E,Tun KM,Dhorda M,Nosten F,Souleymane IM,Blein S,Pachot A,Ariey F,Kaiser K,Ménard D

更新日期：2018-04-24 00:00:00

abstract：BACKGROUND:Control of mosquitoes requires the ability to evaluate new insecticides and to monitor resistance to existing insecticides. Monitoring tools should be flexible and low cost so that they can be deployed in remote, resource poor areas. Ideally, a bioassay should be able to simulate transient contact between mo...

journal_title：Malaria journal

authors： Sternberg ED,Waite JL,Thomas MB

更新日期：2014-12-16 00:00:00

abstract：BACKGROUND:Although it is well known that drug pressure selects for drug-resistant parasites, the role of transmission reduction by insecticide-treated bed nets (ITNs) on drug resistance remains unclear. In this study, the drug resistance profile of current and previous first-line anti-malarials in Kenya was assessed w...

journal_title：Malaria journal

authors： Shah M,Omosun Y,Lal A,Odero C,Gatei W,Otieno K,Gimnig JE,ter Kuile F,Hawley WA,Nahlen B,Kariuki S,Walker E,Slutsker L,Hamel M,Shi YP

更新日期：2015-02-14 00:00:00

abstract：BACKGROUND:Mice with genetic deficiencies in adaptive immunity are used for the grafting of human cells or pathogens, to study human diseases, however, the innate immune responses to xenografts in these mice has received little attention. Using the NOD/SCID Plasmodium falciparum mouse model an analysis of innate defenc...

journal_title：Malaria journal

authors： Arnold L,Tyagi RK,Mejia P,Van Rooijen N,Pérignon JL,Druilhe P

更新日期：2010-07-09 00:00:00

abstract：BACKGROUND:This study aimed to identify factors at individual and community level influencing insecticide-treated net (ITN) usage among groups of women of childbearing age (WOCBA) in Malawi. METHODS:Factors influencing ITN usage in Malawi were assessed through interviews with 16,130 WOCBA (15-49 years) across 850 comm...

journal_title：Malaria journal

authors： Nkoka O,Chuang TW,Chuang KY,Chen YH

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:P25 and P28 are related ookinete surface proteins highly conserved throughout the Plasmodium genus that are under consideration as candidates for inclusion in transmission-blocking vaccines. Previous research using transgenic rodent malaria parasites lacking P25 and P28 has demonstrated that these proteins h...

journal_title：Malaria journal

authors： Baton LA,Ranford-Cartwright LC

更新日期：2005-02-25 00:00:00

abstract：:The incidence and mortality of COVID-19, according to the World Health Organization reports, shows a noticeable difference between North America, Western Europe, and South Asia on one hand and most African countries on the other hand, especially the malaria-endemic countries. Although this observation could be attribu...

journal_title：Malaria journal

authors： Hussein MIH,Albashir AAD,Elawad OAMA,Homeida A

更新日期：2020-12-23 00:00:00

abstract：BACKGROUND:Mosquito transgenesis offers new promises for the genetic control of vector-borne infectious diseases such as malaria and dengue fever. Genetic control strategies require the release of large number of male mosquitoes into field populations, whether they are based on the use of sterile males (sterile insect ...

journal_title：Malaria journal

authors： Marois E,Scali C,Soichot J,Kappler C,Levashina EA,Catteruccia F

更新日期：2012-08-28 00:00:00

abstract：BACKGROUND:There is an urgent need for an effective vaccine to control and eradicate malaria, one of the most serious global infectious diseases. Plasmodium merozoite surface protein 4 (MSP4) has been listed as a blood-stage subunit vaccine candidate for malaria. Infection with Plasmodium ovale species including P. ova...

journal_title：Malaria journal

authors： Uwase J,Chu R,Kassegne K,Lei Y,Shen F,Fu H,Sun Y,Xuan Y,Cao J,Cheng Y

更新日期：2020-03-30 00:00:00

abstract：BACKGROUND:The anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic quinoline anti-malarials (e.g. chloroquine) and semi-synthetic artemisinin derivatives (e.g. artesunate) were developed based on these natural products. Mal...

journal_title：Malaria journal

authors： Lima RB,Rocha e Silva LF,Melo MR,Costa JS,Picanço NS,Lima ES,Vasconcellos MC,Boleti AP,Santos JM,Amorim RC,Chaves FC,Coutinho JP,Tadei WP,Krettli AU,Pohlit AM

更新日期：2015-12-18 00:00:00

abstract：BACKGROUND:Appropriate case management of suspected malaria in Cambodia is critical given anti-malarial drug resistance in the region. Improving diagnosis and the use of recommended malarial treatments is a challenge in Cambodia where self-treatment and usage of drug cocktails is widespread, a notable difference from m...

journal_title：Malaria journal

authors： O'Connell KA,Samandari G,Phok S,Phou M,Dysoley L,Yeung S,Allen H,Littrell M

更新日期：2012-10-05 00:00:00

abstract：BACKGROUND:The emergence of parasite drug resistance, especially Plasmodium falciparum, persists as a major obstacle for malaria control and elimination. To develop effective public health containment strategies, a clear understanding of factors that govern the emergence and spread of resistant parasites in the field i...

journal_title：Malaria journal

authors： Mharakurwa S,Sialumano M,Liu K,Scott A,Thuma P

更新日期：2013-12-19 00:00:00

abstract：BACKGROUND:Members of the Anopheles punctulatus group (AP group) are the primary vectors of human malaria in Papua New Guinea. The AP group includes 13 sibling species, most of them morphologically indistinguishable. Understanding why only certain species are able to transmit malaria requires a better comprehension of ...

journal_title：Malaria journal

authors： Logue K,Chan ER,Phipps T,Small ST,Reimer L,Henry-Halldin C,Sattabongkot J,Siba PM,Zimmerman PA,Serre D

更新日期：2013-02-14 00:00:00

abstract：BACKGROUND:Resistance to multiple classes of insecticides has been detected in the malaria vector Anopheles albimanus in northwest Peru. Acetylcholinesterase (AChE) insensitivity has previously been associated with resistance to organophosphate (OP) and carbamate (CA) insecticides in arthropods. A single point mutation...

journal_title：Malaria journal

authors： Liebman KA,Pinto J,Valle J,Palomino M,Vizcaino L,Brogdon W,Lenhart A

更新日期：2015-02-14 00:00:00

abstract：BACKGROUND:Slash and burn cultivators are a significant risk group for malaria in South-East Asia. As envisaged in the National Strategic Plan for Malaria Elimination, Bangladesh aims to achieve zero indigenous malaria transmission by 2030. For the national plan to move from malaria control to malaria elimination, targ...

journal_title：Malaria journal

authors： Saha A,Sarker M,Kabir M,Lu G,Müller O

更新日期：2019-06-25 00:00:00

abstract：BACKGROUND:With an Annual Parasite Incidence (API) of 132.1, in the high and moderate risks zones, the Maroni area of French Guiana has the second highest malaria incidence of South-America after Guyana (API = 183.54) and far above Brazil (API = 28.25). Malaria transmission is occurring despite strong medical assistanc...

journal_title：Malaria journal

authors： Fouque F,Gaborit P,Carinci R,Issaly J,Girod R

更新日期：2010-03-22 00:00:00

abstract：BACKGROUND:Obtaining single parasite clones is required for many techniques in malaria research. Cloning by limiting dilution using microscopy-based assessment for parasite growth is an arduous and labor-intensive process. An alternative method for the detection of parasite growth in limiting dilution assays is using a...

journal_title：Malaria journal

authors： Butterworth AS,Robertson AJ,Ho MF,Gatton ML,McCarthy JS,Trenholme KR

更新日期：2011-04-18 00:00:00

abstract：BACKGROUND:The diversity of genotyping markers of Plasmodium falciparum depends on transmission intensity. It has been reported that the diversity of the merozoite surface protein 2 (msp2) is greater in areas of high compared to low endemicity, however, results for msp1 were inconsistent. These previous reports relied ...

journal_title：Malaria journal

authors： Schoepflin S,Valsangiacomo F,Lin E,Kiniboro B,Mueller I,Felger I

更新日期：2009-10-30 00:00:00

abstract：BACKGROUND:The malaria vector Anopheles gambiae is polymorphic for chromosomal inversions on the right arm of chromosome 2 that segregate nonrandomly between assortatively mating populations in West Africa. One such inversion, 2Rj, is associated with the BAMAKO chromosomal form endemic to southern Mali and northern Gui...

journal_title：Malaria journal

authors： Coulibaly MB,Pombi M,Caputo B,Nwakanma D,Jawara M,Konate L,Dia I,Fofana A,Kern M,Simard F,Conway DJ,Petrarca V,della Torre A,Traoré S,Besansky NJ

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Arthropod vectors of disease may encounter more than one infected host during the course of their lifetime. The consequences of super-infection to parasite development are rarely investigated, but may have substantial epidemiological and evolutionary consequences. METHODS:Using a rodent malaria model system...

journal_title：Malaria journal

authors： Ferguson HM,Read AF

更新日期：2004-05-19 00:00:00