Efficacy and safety of artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Sudan: a systematic review and meta-analysis.

abstract：BACKGROUND:Malaria is heterogeneously distributed across landscapes. Human population movement (HPM) could link sub-regions with varying levels of transmission, leading to the persistence of disease even in very low transmission settings. Malaria along the Thai-Myanmar border has been decreasing, but remains heterogene...

journal_title：Malaria journal

authors： Saita S,Pan-Ngum W,Phuanukoonnon S,Sriwichai P,Silawan T,White LJ,Parker DM

更新日期：2019-03-08 00:00:00

abstract：BACKGROUND:Parasites from the genus Plasmodium, the aetiological agent of malaria in humans, can also infect non-human primates (NHP), increasing the potential risk of zoonotic transmission with its associated global public health concerns. In Colombia, there are no recent studies on Plasmodium spp. infecting free-rang...

journal_title：Malaria journal

authors： Rondón S,León C,Link A,González C

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:Plasmodium vivax preferentially infects Duffy-positive reticulocytes and infections typically have few parasite-infected cells in the peripheral circulation. These features complicate detection and quantification by flow cytometry (FC) using standard nucleic acid-based staining methods. A simple antibody-bas...

journal_title：Malaria journal

authors： Roobsoong W,Maher SP,Rachaphaew N,Barnes SJ,Williamson KC,Sattabongkot J,Adams JH

更新日期：2014-02-14 00:00:00

abstract：BACKGROUND:The use of insecticide-treated nets (ITN) is an important tool in the Roll Back Malaria (RBM) strategy. For ITNs to be effective they need to be used correctly. Previous studies have shown that many factors, such as wealth, access to health care, education, ethnicity and gender, determine the ownership and u...

journal_title：Malaria journal

authors： Toé LP,Skovmand O,Dabiré KR,Diabaté A,Diallo Y,Guiguemdé TR,Doannio JM,Akogbeto M,Baldet T,Gruénais ME

更新日期：2009-07-29 00:00:00

abstract：:[This corrects the article DOI: 10.1186/s12936-016-1486-0.]. ...

journal_title：Malaria journal

authors： DellaValle B,Hempel C,Staalsoe T,Johansen FF,Kurtzhals JAL

更新日期：2016-09-27 00:00:00

abstract：BACKGROUND:The number of clinical cases of malaria is often recorded in resource constrained or conflict settings as a proxy for disease burden. Interpreting case count data in areas of humanitarian need is challenging due to uncertainties in population size caused by security concerns, resource constraints and populat...

journal_title：Malaria journal

authors： Hellewell J,Walker P,Ghani A,Rao B,Churcher TS

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:Determination of the genetic diversity of malaria parasites can inform the intensity of transmission and identify potential deficiencies in malaria control programmes. This study was conducted to characterize the genetic diversity and allele frequencies of Plasmodium falciparum in Northwest Ethiopia along th...

journal_title：Malaria journal

authors： Mohammed H,Kassa M,Mekete K,Assefa A,Taye G,Commons RJ

更新日期：2018-10-25 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a frequently encountered complication of imported Plasmodium falciparum infection. Markers of structural kidney damage have been found to detect AKI earlier than serum creatinine-based prediction models but have not yet been evaluated in imported malaria. This pilot study aims to...

journal_title：Malaria journal

authors： van Wolfswinkel ME,Koopmans LC,Hesselink DA,Hoorn EJ,Koelewijn R,van Hellemond JJ,van Genderen PJ

更新日期：2016-09-09 00:00:00

abstract：BACKGROUND:Herbal medicine has been a rich source of new drugs exemplified by quinine and artemisinin. In this study, a variety of Japanese traditional herbal medicine ('Kampo') were examined for their potential anti-malarial activities. METHODS:A comprehensive screening methods were designed to identify novel anti-ma...

journal_title：Malaria journal

authors： Teklemichael AA,Mizukami S,Toume K,Mosaddeque F,Kamel MG,Kaneko O,Komatsu K,Karbwang J,Huy NT,Hirayama K

更新日期：2020-06-08 00:00:00

abstract：BACKGROUND:The relationship between mosquito development and temperature is one of the keys to understanding the current and future dynamics and distribution of vector-borne diseases such as malaria. Many process-based models use mean air temperature to estimate larval development times, and hence adult vector densitie...

journal_title：Malaria journal

authors： Paaijmans KP,Imbahale SS,Thomas MB,Takken W

更新日期：2010-07-09 00:00:00

abstract：BACKGROUND:Many malaria-related studies depend on infected red blood cells (iRBCs) as fundamental material; however, infected blood samples from human or animal models include leukocytes (white blood cells or WBCs), especially difficult to separate from iRBCs in cases involving Plasmodium vivax. These host WBCs are a s...

journal_title：Malaria journal

authors： Tao ZY,Xia H,Cao J,Gao Q

更新日期：2011-08-25 00:00:00

abstract：:This article reports the changing pattern of US President's Malaria Initiative-funded IRS in sub-Saharan Africa between 2008 and 2015. IRS coverage in sub-Saharan Africa increased from <2 % of the at-risk population in 2005, to 11 % or 78 million people in 2010, mainly as a result of increased funding from PMI. The sc...

journal_title：Malaria journal

authors： Oxborough RM

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:Knowledge of the population genetics and transmission dynamics of Plasmodium vivax is crucial in predicting the emergence of drug resistance, relapse pattern and novel parasite phenotypes, all of which are relevant to the control of vivax infections. The aim of this study was to analyse changes in the geneti...

journal_title：Malaria journal

authors： Maneerattanasak S,Gosi P,Krudsood S,Tongshoob J,Lanteri CA,Snounou G,Khusmith S

更新日期：2016-02-09 00:00:00

abstract：BACKGROUND:The receptors for adhesion of Plasmodium falciparum-infected red blood cells (RBC) in the placenta have been identified as chondroitin-4-sulphate (C4S) proteoglycans, and the more sulphate-rich chondroitin oligosaccharides have been reported to inhibit adhesion. Since the anti-malarial drug chloroquine accum...

journal_title：Malaria journal

authors： Bhattacharyya S,Solakyildirim K,Zhang Z,Linhardt RJ,Tobacman JK

更新日期：2009-12-17 00:00:00

abstract：BACKGROUND:Control of the major African malaria vector species continues to rely extensively on the application of residual insecticides through indoor house spraying or bed net impregnation. Insecticide resistance is undermining the sustainability of these control strategies. Alternatives to the currently available co...

journal_title：Malaria journal

authors： Kikankie CK,Brooke BD,Knols BG,Koekemoer LL,Farenhorst M,Hunt RH,Thomas MB,Coetzee M

更新日期：2010-03-08 00:00:00

abstract：BACKGROUND:The malaria vector Anopheles gambiae is polymorphic for chromosomal inversions on the right arm of chromosome 2 that segregate nonrandomly between assortatively mating populations in West Africa. One such inversion, 2Rj, is associated with the BAMAKO chromosomal form endemic to southern Mali and northern Gui...

journal_title：Malaria journal

authors： Coulibaly MB,Pombi M,Caputo B,Nwakanma D,Jawara M,Konate L,Dia I,Fofana A,Kern M,Simard F,Conway DJ,Petrarca V,della Torre A,Traoré S,Besansky NJ

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:A reversal of chloroquine (CQ) resistance following a period of withdrawal has raised the possibility of its re-introduction. This study evaluated the current prevalence of Pfcrt and Pfmdr1 alleles in Plasmodium falciparum isolates, 11 years after CQ withdrawal in Southeast Nigeria. METHODS:Filter-paper blo...

journal_title：Malaria journal

authors： Ikegbunam MN,Nkonganyi CN,Thomas BN,Esimone CO,Velavan TP,Ojurongbe O

更新日期：2019-10-07 00:00:00

abstract：BACKGROUND:A deeper understanding of the ecology and small-scale heterogeneity of malaria transmission is essential for the design of effective prevention, control and elimination interventions. The spatial and temporal distribution of malaria vectors was investigated in five villages in close proximity to a hydro-agri...

journal_title：Malaria journal

authors： Diakité NR,Guindo-Coulibaly N,Adja AM,Ouattara M,Coulibaly JT,Utzinger J,N'Goran EK

更新日期：2015-09-05 00:00:00

abstract：BACKGROUND:Successful reduction of malaria transmission to very low levels has made Isabel Province, Solomon Islands, a target for early elimination by 2014. High malaria transmission in neighbouring provinces and the potential for local asymptomatic infections to cause malaria resurgence highlights the need for sub-na...

journal_title：Malaria journal

authors： Atkinson JA,Johnson ML,Wijesinghe R,Bobogare A,Losi L,O'Sullivan M,Yamaguchi Y,Kenilorea G,Vallely A,Cheng Q,Ebringer A,Bain L,Gray K,Harris I,Whittaker M,Reid H,Clements A,Shanks D

更新日期：2012-03-30 00:00:00

abstract：BACKGROUND:It was unknown whether the main reservoir of Plasmodium falciparum and Plasmodium vivax, which infects mosquitoes in Thailand, was (a) in people feeling sufficiently ill with malaria to come to a clinic or (b) in people who had remained in their home villages with some fever symptoms or with none. METHODS:M...

journal_title：Malaria journal

authors： Pethleart A,Prajakwong S,Suwonkerd W,Corthong B,Webber R,Curtis C

更新日期：2004-09-22 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether a selection of South African ethnomedicinal plants included in this study displayed insecticidal properties when screened against adult stages of the mosquito. METHODS:381 crude extracts of 80 plant taxa in 42 families were sprayed onto ceramic tiles and screened...

journal_title：Malaria journal

authors： Maharaj R,Maharaj V,Crouch NR,Bhagwandin N,Folb PI,Pillay P,Gayaram R

更新日期：2011-08-11 00:00:00

abstract：BACKGROUND:The evolution of drug resistance in malaria parasites highlights a need to identify and evaluate strategies that could extend the useful therapeutic life of anti-malarial drugs. Such strategies are deployed to best effect before resistance has emerged, under conditions of great uncertainty. METHODS:Here, th...

journal_title：Malaria journal

authors： Smith DL,Klein EY,McKenzie FE,Laxminarayan R

更新日期：2010-07-23 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) largely account for the scale-up of malaria diagnosis in endemic settings. However, diversity in labelling including the instructions for use (IFU) limits their interchangeability and user-friendliness. Uniform, easy to follow and consistent labelling, aligned with international...

journal_title：Malaria journal

authors： Jacobs J,Barbé B,Gillet P,Aidoo M,Serra-Casas E,Van Erps J,Daviaud J,Incardona S,Cunningham J,Visser T

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Sub-Saharan Africa (SSA) has embarked on a new era of dam building to improve food security and promote economic development. Nonetheless, the future impacts of dams on malaria transmission are poorly understood and seldom investigated in the context of climate and demographic change. METHODS:The distributi...

journal_title：Malaria journal

authors： Kibret S,Lautze J,McCartney M,Nhamo L,Wilson GG

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:The emergence of parasite drug resistance, especially Plasmodium falciparum, persists as a major obstacle for malaria control and elimination. To develop effective public health containment strategies, a clear understanding of factors that govern the emergence and spread of resistant parasites in the field i...

journal_title：Malaria journal

authors： Mharakurwa S,Sialumano M,Liu K,Scott A,Thuma P

更新日期：2013-12-19 00:00:00

abstract：BACKGROUND:Mice with genetic deficiencies in adaptive immunity are used for the grafting of human cells or pathogens, to study human diseases, however, the innate immune responses to xenografts in these mice has received little attention. Using the NOD/SCID Plasmodium falciparum mouse model an analysis of innate defenc...

journal_title：Malaria journal

authors： Arnold L,Tyagi RK,Mejia P,Van Rooijen N,Pérignon JL,Druilhe P

更新日期：2010-07-09 00:00:00

abstract：BACKGROUND:Very few data on anti-malarial efficacy are available from the Democratic Republic of Congo (DRC). DRC changed its anti-malarial treatment policy to amodiaquine (AQ) and artesunate (AS) in 2005. METHODS:The results of two in vivo efficacy studies, which tested AQ and sulphadoxine-pyrimethamine (SP) monother...

journal_title：Malaria journal

authors： Bonnet M,Broek Iv,van Herp M,Urrutia PP,van Overmeir C,Kyomuhendo J,Ndosimao CN,Ashley E,Guthmann JP

更新日期：2009-08-10 00:00:00

abstract：BACKGROUND:The diversity and abundance of Anopheles larvae has significant influence on the resulting adult mosquito population and hence the dynamics of malaria transmission. Studies were conducted to examine larval habitat dynamics and ecological factors affecting survivorship of aquatic stages of malaria vectors in ...

journal_title：Malaria journal

authors： Mwangangi JM,Shililu J,Muturi EJ,Muriu S,Jacob B,Kabiru EW,Mbogo CM,Githure J,Novak RJ

更新日期：2010-08-09 00:00:00

abstract：BACKGROUND:The malaria rapid diagnostic tests (RDTs) are now widely used in the world. Compared to Plasmodium falciparum, a poor sensitivity of RDTs was reported against Plasmodium vivax based on the adopted antibody against pan-Plasmodium antigen lactate dehydrogenase (pLDH) or aldolase. Levels of pLDH were measured f...

journal_title：Malaria journal

authors： Jang JW,Cho CH,Han ET,An SS,Lim CS

更新日期：2013-06-03 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a common complication of malaria. In low resource settings, a lack of diagnostic tools and delayed treatment of malaria associated AKI lead to significant morbidity and mortality. The aim of this study was to assess the diagnostic performance of salivary urea nitrogen (SUN) dipst...

journal_title：Malaria journal

authors： Calice-Silva V,Sacomboio E,Raimann JG,Evans R,Dos Santos Sebastião C,Tchivango AT,Kotanko P,Levin N,Pecoits-Filho R

更新日期：2018-12-18 00:00:00