The contribution of agricultural insecticide use to increasing insecticide resistance in African malaria vectors.

abstract：BACKGROUND:In the context of malaria elimination/eradication, drugs that are effective against the different developmental stages of the parasite are highly desirable. The oldest synthetic anti-malarial drug, the thiazine dye methylene blue (MB), is known for its activity against Plasmodium blood stages, including game...

journal_title：Malaria journal

authors： Bosson-Vanga H,Franetich JF,Soulard V,Sossau D,Tefit M,Kane B,Vaillant JC,Borrmann S,Müller O,Dereuddre-Bosquet N,Le Grand R,Silvie O,Mazier D

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:The erythrocytic stage of Plasmodium falciparum parasites in humans is clinically important, as the parasites at this growth stage causes malarial symptoms. Most of the currently available anti-malarial drugs target this stage, but the emergence and spread of parasites resistant to anti-malarial drugs are a ...

journal_title：Malaria journal

authors： Tougan T,Toya Y,Uchihashi K,Horii T

更新日期：2019-01-14 00:00:00

abstract：BACKGROUND:The use of anti-malarial drug combinations with artemisinin or with one of its derivatives is now widely recommended to overcome drug resistance in falciparum as well as vivax malaria. The fixed oral dose artemisinin-naphthoquine combination (ANQ, ARCO) is a newer artemisinin-based combination (ACT) therapy ...

journal_title：Malaria journal

authors： Hombhanje FW,Linge D,Saweri A,Kuanch C,Jones R,Toraso S,Geita J,Masta A,Kevau I,Hiawalyer G,Sapuri M

更新日期：2009-08-12 00:00:00

abstract：BACKGROUND:Effective and timely treatment is an essential aspect of malaria control, but remains a challenge in many parts of sub-Saharan Africa. The objective of this study was to describe young children's access to malaria treatment in Nouna Health District, Burkina Faso. METHODS:In February/March 2006, a survey was...

journal_title：Malaria journal

authors： Tipke M,Louis VR,Yé M,De Allegri M,Beiersmann C,Sié A,Mueller O,Jahn A

更新日期：2009-11-24 00:00:00

abstract：BACKGROUND:It is estimated that over 70% of patients with suspected malaria in sub-Saharan Africa, diagnose and manage their illness at home without referral to a formal health clinic. Of those patients who do attend a formal health clinic, malaria overdiagnosis rates are estimated to range between 30-70%. METHODS:Thi...

journal_title：Malaria journal

authors： Hume JC,Barnish G,Mangal T,Armázio L,Streat E,Bates I

更新日期：2008-02-18 00:00:00

abstract：BACKGROUND:Health care demand studies help to examine the behaviour of individuals and households during illnesses. Few of existing health care demand studies examine the choice of treatment services for childhood illnesses. Besides, in their analyses, many of the existing studies compare alternative treatment options ...

journal_title：Malaria journal

authors： Nonvignon J,Aikins MK,Chinbuah MA,Abbey M,Gyapong M,Garshong BN,Fia S,Gyapong JO

更新日期：2010-06-28 00:00:00

abstract：BACKGROUND:Ensuring the quality of malaria medicines is crucial in working toward malaria control and eventual elimination. Unlike other validated tests that can assess all critical quality attributes, which is the standard for determining the quality of medicines, basic tests are significantly less expensive, faster, ...

journal_title：Malaria journal

authors： Pribluda VS,Barojas A,Añez A,López CG,Figueroa R,Herrera R,Nakao G,Nogueira FH,Pianetti GA,Povoa MM,Viana GM,Gomes MS,Escobar JP,Sierra OL,Norena SP,Veloz R,Bravo MS,Aldás MR,Hindssemple A,Collins M,Ceron N,Kris

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Polyclonal B-cell activation is well known to occur in Plasmodium infections, but its role in pathogenesis or protection remains unclear. However, protective properties of natural antibodies have previously been demonstrated in other contexts. METHODS:Sera from asymptomatic and symptomatic Plasmodium-infect...

journal_title：Malaria journal

authors： Fesel C,Goulart LF,Silva Neto A,Coelho A,Fontes CJ,Braga EM,Vaz NM

更新日期：2005-01-20 00:00:00

abstract：BACKGROUND:Currently available diagnostic techniques of Plasmodium falciparum infection are not optimal for non-invasive, population-based screening for malaria. It was hypothesized that a mass spectrometry-based metabolomics approach could identify urinary biomarkers of falciparum malaria. METHODS:The study used a ca...

journal_title：Malaria journal

authors： Abdelrazig S,Ortori CA,Davey G,Deressa W,Mulleta D,Barrett DA,Amberbir A,Fogarty AW

更新日期：2017-05-30 00:00:00

abstract：BACKGROUND:Very few data on anti-malarial efficacy are available from the Democratic Republic of Congo (DRC). DRC changed its anti-malarial treatment policy to amodiaquine (AQ) and artesunate (AS) in 2005. METHODS:The results of two in vivo efficacy studies, which tested AQ and sulphadoxine-pyrimethamine (SP) monother...

journal_title：Malaria journal

authors： Bonnet M,Broek Iv,van Herp M,Urrutia PP,van Overmeir C,Kyomuhendo J,Ndosimao CN,Ashley E,Guthmann JP

更新日期：2009-08-10 00:00:00

abstract：BACKGROUND:Resistance of Plasmodium falciparum to anti-malarial drugs has hampered efforts to eradicate malaria. Recent reports of a decline in the prevalence of chloroquine-resistant P. falciparum in several countries, including Malawi and Zambia, is raising the hope of reintroducing chloroquine in the near future, id...

journal_title：Malaria journal

authors： Dagnogo O,Ako AB,Ouattara L,Dago ND,Coulibaly DN,Touré AO,Djaman JA

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:Malaria can be eradicated from islands. To assess the prospects for eradication of malaria from the island of Príncipe in the Gulf of Guinea, we fitted a mathematical model to age-prevalence curves and thus obtained estimates of the vectorial capacity and of the basic reproductive number (R0) for malaria. M...

journal_title：Malaria journal

authors： Hagmann R,Charlwood JD,Gil V,Ferreira C,do Rosário V,Smith TA

更新日期：2003-06-18 00:00:00

abstract：BACKGROUND:Mosquitoes of the Anopheles gambiae species complex are the primary vectors of human malaria in sub-Saharan Africa. Many host genes have been shown to affect Plasmodium development in the mosquito, and so are expected to engage in an evolutionary arms race with the pathogen. However, there is little conclusi...

journal_title：Malaria journal

authors： Obbard DJ,Welch JJ,Little TJ

更新日期：2009-06-04 00:00:00

abstract：BACKGROUND:Malaria is a potentially lethal illness for which preventive measures are not optimally used among all travellers. Travellers visiting friends and relatives in their country of origin (VFRs) are known to use chemoprophylaxis less consistently compared to tourist travellers. In this study, factors explaining ...

journal_title：Malaria journal

authors： Wieten RW,Harting J,Biemond PM,Grobusch MP,van Vugt M

更新日期：2013-10-10 00:00:00

abstract：BACKGROUND:In the Republic of Korea (ROK), six sibling species of the Anopheles sinensis complex are considered the vector species of malaria, but data on their susceptibilities to malaria and vector capacities have been controversial. The intensive use of insecticides has contributed to the rapid development and sprea...

journal_title：Malaria journal

authors： Kang S,Jung J,Lee S,Hwang H,Kim W

更新日期：2012-05-03 00:00:00

abstract：BACKGROUND:In the Tanga District of coastal Tanzania, malaria is one of the primary causes of mortality for children under the age of five. While some children are treated with malaria medications in biomedical facilities, as the World Health Organization recommends, others receive home-care or treatment from tradition...

journal_title：Malaria journal

authors： Foster D,Vilendrer S

更新日期：2009-10-27 00:00:00

abstract：BACKGROUND:Malaria remains highly endemic in Cameroon. The rapid emergence and spread of drug resistance was responsible for the change from monotherapies to artemisinin-based combinations. This systematic review and meta-analysis aimed to determine the prevalence and distribution of Plasmodium falciparum drug resistan...

journal_title：Malaria journal

authors： Niba PTN,Nji AM,Evehe MS,Ali IM,Netongo PM,Ngwafor R,Moyeh MN,Ngum LN,Ndum OE,Acho FA,Mbu'u CM,Fosah DA,Atogho-Tiedeu B,Achonduh-Atijegbe O,Djokam-Dadjeu R,Chedjou JPK,Bigoga JD,Moukoko CEE,Ajua A,Achidi E,Tallah

更新日期：2021-01-09 00:00:00

abstract：BACKGROUND:Glucose 6-phosphate dehydrogenase (G6PD) is an enzyme involved in prevention of cellular oxidative damage, particularly protecting erythrocytes from haemolysis. An estimated 400 million people present variable degrees of inherited G6PD deficiency (G6PDd) which puts them at risk for developing haemolysis trig...

journal_title：Malaria journal

authors： Valencia SH,Ocampo ID,Arce-Plata MI,Recht J,Arévalo-Herrera M

更新日期：2016-05-26 00:00:00

abstract：:April 25 marks World Malaria Day, an opportunity for those who work to defeat the illness, to review progress and renew commitments. After a decade of steady success, this year's commemoration of the date is also an opportunity to reconsider current approaches and assess the state of the science needed to keep pace in...

journal_title：Malaria journal

authors： Slutsker L,Kachur SP

更新日期：2013-04-24 00:00:00

abstract：BACKGROUND:Intermittent preventive treatment with sulphadoxine-pyrimethamine (IPT-SP) is currently the recommended regimen for prevention of malaria in pregnancy in endemic areas. This study sets out to evaluate the effectiveness of IPT-SP in the prevention of maternal and placental malaria in parturient mothers in Iba...

journal_title：Malaria journal

authors： Falade CO,Yusuf BO,Fadero FF,Mokuolu OA,Hamer DH,Salako LA

更新日期：2007-07-06 00:00:00

abstract：BACKGROUND:Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders' perspectives are thus critical for informed recommendation of the vaccine in Tanzania. This paper presents the views of stakeholders with regards to malaria vaccine in 12 Tanzanian ...

journal_title：Malaria journal

authors： Mtenga S,Kimweri A,Romore I,Ali A,Exavery A,Sicuri E,Tanner M,Abdulla S,Lusingu J,Kafuruki S

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:Plasmodium falciparum readily develops resistance to the anti-folates pyrimethamine and proguanil via a characteristic set of mutations in the dihydrofolate reductase (PfDHFR) gene that leads to reduced competitive drug binding at the enzyme's active site. Analogous mutations can be found in the DHFR gene in...

journal_title：Malaria journal

authors： Choowongkomon K,Theppabutr S,Songtawee N,Day NP,White NJ,Woodrow CJ,Imwong M

更新日期：2010-03-02 00:00:00

abstract：BACKGROUND:Plasmodium malariae is the most neglected of the six human malaria species and it is still unknown which is the mechanism underlying the long latency of this Plasmodium. CASE PRESENTATION:A case of PCR-confirmed P. malariae recurrence in a 52-year old Italian man was observed 5 months after a primary attack...

journal_title：Malaria journal

authors： Grande R,Antinori S,Meroni L,Menegon M,Severini C

更新日期：2019-05-14 00:00:00

abstract：BACKGROUND:Helminths and malaria are among the most prevalent infectious diseases in the world. They both occur in tropical area where they often affect the same populations. There are studies suggesting an effect of helminths on malariometric indices. For example, malaria attacks as well as disease severity has been s...

journal_title：Malaria journal

authors： Ateba-Ngoa U,Adegnika AA,Zinsou JF,Kassa Kassa RF,Smits H,Massinga-Loembe M,Mordmüller B,Kremsner PG,Yazdanbakhsh M

更新日期：2015-02-25 00:00:00

abstract：BACKGROUND:With less than one severe case per year in average, Plasmodium vivax is very rarely associated with severe imported malaria in France. Two cases of P. vivax severe malaria occurred in patients with no evident co-morbidity. Interestingly, both cases did not occur at the primary infection but during relapses. ...

journal_title：Malaria journal

authors： Izri A,Cojean S,Leblanc C,Cohen Y,Bouchaud O,Durand R

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:Monitoring and evaluation of malaria programmes may require a combination of approaches to detect any effects of control. This is particularly true at lower transmission levels where detecting both infection and exposure to infection will provide additional evidence of any change. This paper describes use of...

journal_title：Malaria journal

authors： Stevenson JC,Stresman GH,Baidjoe A,Okoth A,Oriango R,Owaga C,Marube E,Bousema T,Cox J,Drakeley C

更新日期：2015-10-26 00:00:00

abstract：BACKGROUND:Insecticide resistance in Anopheles coluzzii mosquitoes has become widespread throughout West Africa including in Burkina Faso. The insecticide resistance allele (kdr or L1014F) is a prime indicator that is highly correlated with phenotypic resistance in West Africa. Studies from Benin, Ghana and Mali have s...

journal_title：Malaria journal

authors： Hanemaaijer MJ,Higgins H,Eralp I,Yamasaki Y,Becker N,Kirstein OD,Lanzaro GC,Lee Y

更新日期：2019-04-11 00:00:00

abstract：BACKGROUND:Artemisinin-based combination therapy (ACT) has been recommended for the treatment of falciparum malaria by the World Health Organization. Though India has already switched to ACT for treating falciparum malaria, there is need to have multiple options of alternative forms of ACT. A randomized trial was condu...

journal_title：Malaria journal

authors： Anvikar AR,Sharma B,Shahi BH,Tyagi PK,Bose TK,Sharma SK,Srivastava P,Srivastava B,Kiechel JR,Dash AP,Valecha N

更新日期：2012-03-30 00:00:00

abstract：BACKGROUND:Shandong Province experienced a declining malaria trend of local-acquired transmission, but the increasing imported malaria remains a challenge. Therefore, understanding the epidemiological characteristics of malaria and the control and elimination strategy and interventions is needed for better planning to ...

journal_title：Malaria journal

authors： Kong X,Liu X,Tu H,Xu Y,Niu J,Wang Y,Zhao C,Kou J,Feng J

更新日期：2017-01-31 00:00:00

abstract：BACKGROUND:The screening of lead compounds against in vitro parasite cultures is an essential step in the development of novel anti-malarial drugs, but currently relies on laboratory parasite lines established in vitro during the last century. This study sought to establish in continuous culture a series of recent Plas...

journal_title：Malaria journal

authors： van Schalkwyk DA,Burrow R,Henriques G,Gadalla NB,Beshir KB,Hasford C,Wright SG,Ding XC,Chiodini PL,Sutherland CJ

更新日期：2013-09-13 00:00:00