Transcript and protein expression profile of PF11_0394, a Plasmodium falciparum protein expressed in salivary gland sporozoites.

abstract：:Following publication of the original article [1], one of the authors has highlighted an xml-related discrepancy concerning the author group titled 'Additional Tracking Resistance to Artemisinin Collaboration authors (TRAC Group Authorship)', listed under the Acknowledgements section. ...

journal_title：Malaria journal

authors： Srimuang K,Miotto O,Lim P,Fairhurst RM,Kwiatkowski DP,Woodrow CJ,Imwong M,Tracking Resistance to Artemisinin Collaboration.

更新日期：2018-09-10 00:00:00

abstract：BACKGROUND:Plasmodium vivax is very rarely seen in West Africa, although specific detection methods are not widely applied in the region, and it is now considered to be absent from North Africa. However, this parasite species has recently been reported to account for most malaria cases in Nouakchott, the capital of Mau...

journal_title：Malaria journal

authors： Ba H,Duffy CW,Ahouidi AD,Deh YB,Diallo MY,Tandia A,Conway DJ

更新日期：2016-02-09 00:00:00

abstract：BACKGROUND:Arthropod vectors of disease may encounter more than one infected host during the course of their lifetime. The consequences of super-infection to parasite development are rarely investigated, but may have substantial epidemiological and evolutionary consequences. METHODS:Using a rodent malaria model system...

journal_title：Malaria journal

authors： Ferguson HM,Read AF

更新日期：2004-05-19 00:00:00

abstract：BACKGROUND:Programmes of pre-elimination of malaria have been implemented in Senegal since 2010, and the burden of malaria has decreased substantially. These changes in the epidemiology should be monitored with effective tools that allow changes in patterns of transmission to be estimated. In Dielmo and Ndiop, two vill...

journal_title：Malaria journal

authors： Diop F,Richard V,Diouf B,Sokhna C,Diagne N,Trape JF,Faye MM,Tall A,Diop G,Balde AT

更新日期：2014-03-06 00:00:00

abstract：:Malaria vaccines are considered amongst the most important modalities for potential elimination of malaria disease and transmission. Research and development in this field has been an area of intense effort by many groups over the last few decades. Despite this, there is currently no licensed malaria vaccine. Research...

journal_title：Malaria journal

authors： Mwangoka G,Ogutu B,Msambichaka B,Mzee T,Salim N,Kafuruki S,Mpina M,Shekalaghe S,Tanner M,Abdulla S

更新日期：2013-03-04 00:00:00

abstract：BACKGROUND:This paper reports on the availability of diagnostic tools and recommended anti-malarials in the 12-month period immediately following the implementation of a new national malaria treatment protocol (NMTP) in Papua New Guinea (PNG). Health worker adherence to the new NMTP is also examined and comparisons mad...

journal_title：Malaria journal

authors： Pulford J,Kurumop SF,Ura Y,Siba PM,Mueller I,Hetzel MW

更新日期：2013-11-27 00:00:00

abstract：BACKGROUND:Malaria transmission in the peri-Iquitos region of Amazonian Peru has been designated as seasonal and hypo-endemic with recently described hyper-endemic hotspots. Despite relatively recent distribution of long-lasting insecticidal bed nets (LLINs), malaria in Amazonian Peru persists and increased substantial...

journal_title：Malaria journal

authors： Moreno M,Saavedra MP,Bickersmith SA,Lainhart W,Tong C,Alava F,Vinetz JM,Conn JE

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:Insecticide-treated nets (ITN) and long-lasting insecticidal treated nets (LLIN) are important means of malaria prevention. Although there is consensus regarding their importance, there is uncertainty as to which delivery strategies are optimal for dispensing these life saving interventions. A targeted mass ...

journal_title：Malaria journal

authors： Beer N,Ali AS,de Savigny D,Al-Mafazy AW,Ramsan M,Abass AK,Omari RS,Björkman A,Källander K

更新日期：2010-06-18 00:00:00

abstract：BACKGROUND:Malaria is a major public health issue in Burundi in terms of both morbidity and mortality, with around 2.5 million clinical cases and more than 15,000 deaths each year. It is still the single main cause of mortality in pregnant women and children below five years of age. Because of the severe health and eco...

journal_title：Malaria journal

authors： Nkurunziza H,Gebhardt A,Pilz J

更新日期：2011-08-11 00:00:00

abstract：BACKGROUND:Global malaria control strategies highlight the need to increase early uptake of effective antimalarials for childhood fevers in endemic settings, based on a presumptive diagnosis of malaria in this age group. Many control programmes identify private medicine sellers as important targets to promote effective...

journal_title：Malaria journal

authors： Abuya TO,Mutemi W,Karisa B,Ochola SA,Fegan G,Marsh V

更新日期：2007-05-10 00:00:00

abstract：BACKGROUND:In formerly endemic areas where malaria transmission has declined, levels of population immunity to Plasmodium falciparum provide information on continued malaria transmission and potentially susceptible populations. Traditional techniques for measuring serological responses to P. falciparum antigens use pla...

journal_title：Malaria journal

authors： Chidi AP,Chishimba S,Kobayashi T,Hamapumbu H,Mharakurwa S,Thuma PE,Moss WJ

更新日期：2011-06-10 00:00:00

abstract：BACKGROUND:Severe anaemia can develop in the aftermath of Plasmodium falciparum malaria because of protracted bone marrow suppression, possibly due to residual subpatent parasites. MATERIALS AND METHODS:Blood was collected from patients with recent malaria and negative malaria microscopy. Detection of the Plasmodium a...

journal_title：Malaria journal

authors： Helleberg M,Goka BQ,Akanmori BD,Obeng-Adjei G,Rodriques O,Kurtzhals JA

更新日期：2005-12-01 00:00:00

abstract：:Plasmodium falciparum infections present novel challenges for vaccine development, including parasite replication dynamics not previously encountered for viral pathogens, and enormous diversity in target antigens. These challenges are illustrated by using a mathematical model to describe the association between the pr...

journal_title：Malaria journal

authors： White MT,Smith DL

更新日期：2013-08-08 00:00:00

abstract：BACKGROUND:During malaria infection the Toll-like receptor 9 (TLR9) is activated through induction with plasmodium DNA or another malaria motif not yet identified. Although TLR9 activation by malaria parasites is well reported, the implication to the susceptibility to severe malaria is not clear. The aim of this study ...

journal_title：Malaria journal

authors： Campino S,Forton J,Auburn S,Fry A,Diakite M,Richardson A,Hull J,Jallow M,Sisay-Joof F,Pinder M,Molyneux ME,Taylor TE,Rockett K,Clark TG,Kwiatkowski DP

更新日期：2009-03-13 00:00:00

abstract：BACKGROUND:Recent progress in malaria control has caused renewed interest in mass drug administration (MDA) as a potential elimination strategy but the evidence base is limited. China has extensive experience with MDA, but it is not well documented. METHODS:An ecological study was conducted to describe the use of MDA ...

journal_title：Malaria journal

authors： Hsiang MS,Hwang J,Tao AR,Liu Y,Bennett A,Shanks GD,Cao J,Kachur SP,Feachem RG,Gosling RD,Gao Q

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Malaria is a leading cause of mortality and morbidity in Mozambique, with nearly three-quarters of the country's malaria-related deaths occurring in children younger than five years. A malaria vaccine is not yet available, but planning is underway for a possible introduction, as soon as one becomes available...

journal_title：Malaria journal

authors： Bingham A,Gaspar F,Lancaster K,Conjera J,Collymore Y,Ba-Nguz A

更新日期：2012-11-28 00:00:00

abstract：BACKGROUND:Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be expedited. Molecular biology techniques used for monitoring rely on the detection of k13 validated mutants by using PCR and Sanger sequencing approach, usually not ava...

journal_title：Malaria journal

authors： Vachot-Ganée L,Khim N,Iannello A,Legrand E,Kim S,Eam R,Khean C,Ken M,Ashley E,Tun KM,Dhorda M,Nosten F,Souleymane IM,Blein S,Pachot A,Ariey F,Kaiser K,Ménard D

更新日期：2018-04-24 00:00:00

abstract：:Artesunate (AS) is a clinically versatile artemisinin derivative utilized for the treatment of mild to severe malaria infection. Given the therapeutic significance of AS and the necessity of appropriate AS dosing, substantial research has been performed investigating the pharmacokinetics of AS and its active metabolit...

journal_title：Malaria journal

authors： Morris CA,Duparc S,Borghini-Fuhrer I,Jung D,Shin CS,Fleckenstein L

更新日期：2011-09-13 00:00:00

abstract：BACKGROUND:Malaria is a major health problem in sub-Saharan Africa where over 90% of the world's malaria cases occur. Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization as first-line and second-line treatments for uncomplicated falciparum malaria. However, there are a growing nu...

journal_title：Malaria journal

authors： Ndwigah S,Stergachis A,Abuga K,Mugo H,Kibwage I

更新日期：2018-09-15 00:00:00

abstract：BACKGROUND:Drug combination therapy is the frontline of malaria treatment. There is an ever-accelerating need for new, efficacious combination therapies active against drug resistant malaria. Proven drugs already in the treatment pipeline, such as the quinolines, are important components of current combination therapy ...

journal_title：Malaria journal

authors： Gorka AP,Jacobs LM,Roepe PD

更新日期：2013-09-18 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) have become the most common diagnostic tool for detection of Plasmodium falciparum malaria, in particular in remote areas. RDT blood spots provide a source of parasite DNA for molecular analysis. In this study, the utility of RDTs for molecular analysis and the performance of di...

journal_title：Malaria journal

authors： Srisutham S,Suwannasin K,Mathema VB,Sriprawat K,Smithuis FM,Nosten F,White NJ,Dondorp AM,Imwong M

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:Polymorphisms within the PfATP6 gene have been indicated as potential molecular markers for artemisinin efficacy. Since 2004, the use of artemisinin combination therapy (ACT) was introduced as first-line treatment of the uncomplicated malaria cases in Suriname. The aim of this research was to determine chang...

journal_title：Malaria journal

authors： Adhin MR,Labadie-Bracho M,Vreden SG

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) have become an essential tool in the contemporary malaria control and management programmes in the world. This study aims to evaluate the performance of two commonly used RDTs for malaria diagnosis in the China-Myanmar border area. METHODS:A total 606 febrile patients in the Ch...

journal_title：Malaria journal

authors： Yan J,Li N,Wei X,Li P,Zhao Z,Wang L,Li S,Li X,Wang Y,Li S,Yang Z,Zheng B,Zhou G,Yan G,Cui L,Cao Y,Fan Q

更新日期：2013-02-22 00:00:00

abstract：BACKGROUND:For future eradication strategies of malaria it is important to control the transmission of gametocytes from humans to the anopheline vector which causes the spread of the disease. Sensitive, non-invasive methods to detect gametocytes under field conditions can play a role in monitoring transmission potentia...

journal_title：Malaria journal

authors： Kast K,Berens-Riha N,Zeynudin A,Abduselam N,Eshetu T,Löscher T,Wieser A,Shock J,Pritsch M

更新日期：2013-12-04 00:00:00

abstract：BACKGROUND:There is an urgent need to develop and test novel compounds against malaria infection. Carrageenans, sulphated polysaccharides derived from seaweeds, have been previously shown to inhibit Plasmodium falciparum in vitro. However, they are inflammatory and alter the permeability of the blood-brain barrier, rai...

journal_title：Malaria journal

authors： Recuenco FC,Takano R,Chiba S,Sugi T,Takemae H,Murakoshi F,Ishiwa A,Inomata A,Horimoto T,Kobayashi Y,Horiuchi N,Kato K

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:Shandong Province experienced a declining malaria trend of local-acquired transmission, but the increasing imported malaria remains a challenge. Therefore, understanding the epidemiological characteristics of malaria and the control and elimination strategy and interventions is needed for better planning to ...

journal_title：Malaria journal

authors： Kong X,Liu X,Tu H,Xu Y,Niu J,Wang Y,Zhao C,Kou J,Feng J

更新日期：2017-01-31 00:00:00

abstract：BACKGROUND:Multiple red blood cell (RBC) variants appear to offer protection against the most severe forms of Plasmodium falciparum malaria. Associations between these variants and uncomplicated malaria are less clear. METHODS:Data from a longitudinal cohort study conducted in 3 sub-counties in Uganda was used to quan...

journal_title：Malaria journal

authors： Kakande E,Greenhouse B,Bajunirwe F,Drakeley C,Nankabirwa JI,Walakira A,Nsobya SL,Katureebe A,Rek J,Arinaitwe E,Rosenthal PJ,Kamya MR,Dorsey G,Rodriguez-Barraquer I

更新日期：2020-01-15 00:00:00

abstract：BACKGROUND:Community-based service delivery is vital to the effectiveness, affordability and sustainability of vector control generally, and to labour-intensive larval source management (LSM) programmes in particular. CASE DESCRIPTION:The institutional evolution of a city-level, community-based LSM programme over 14 y...

journal_title：Malaria journal

authors： Chaki PP,Kannady K,Mtasiwa D,Tanner M,Mshinda H,Kelly AH,Killeen GF

更新日期：2014-06-25 00:00:00

abstract：BACKGROUND:Anti-malarial resistance in Plasmodium falciparum remains an obstacle for malaria control. Resistance-associated genes were analysed in Brazilian samples over four decades to evaluate the impact of different treatment regimens on the parasite genetic profile. METHODS:Samples were collected on filter paper f...

journal_title：Malaria journal

authors： Inoue J,Lopes D,do Rosário V,Machado M,Hristov AD,Lima GF,Costa-Nascimento MJ,Segurado AC,Di Santi SM

更新日期：2014-09-19 00:00:00

abstract：BACKGROUND:KwaZulu-Natal, one of South Africa's three malaria endemic provinces, is nearing malaria elimination, reporting fewer than 100 locally-acquired cases annually since 2010. Despite sustained implementation of essential interventions, including annual indoor residual spraying, prompt case detection using malari...

journal_title：Malaria journal

authors： Raman J,Gast L,Balawanth R,Tessema S,Brooke B,Maharaj R,Munhenga G,Tshikae P,Lakan V,Mwamba T,Makowa H,Sangweni L,Mkhabela M,Zondo N,Mohulatsi E,Nyawo Z,Ngxongo S,Msimang S,Dagata N,Greenhouse B,Birkholtz LM,Shi

更新日期：2020-04-15 00:00:00