The quality of anti-malarial medicines in Embu County, Kenya.

abstract：BACKGROUND:IPTi delivered through EPI has been shown to reduce the incidence of clinical malaria by 20-59%. However, new health interventions can only be effective if they are also socially and culturally acceptable. It is also crucial to ensure that attitudes to IPTi do not negatively influence attitudes to and uptake...

journal_title：Malaria journal

authors： Gysels M,Pell C,Mathanga DP,Adongo P,Odhiambo F,Gosling R,Akweongo P,Mwangi R,Okello G,Mangesho P,Slutsker L,Kremsner PG,Grobusch MP,Hamel MJ,Newman RD,Pool R

更新日期：2009-08-10 00:00:00

abstract：BACKGROUND:The impact of sulfadoxine-pyrimethamine (SP) used as intermittent preventive treatment during pregnancy (IPTp-SP) on mutant parasite selection has been poorly documented in Burkina Faso. This study sought first to explore the relationship between IPTp-SP and the presence of mutant parasites. Second, to asses...

journal_title：Malaria journal

authors： Cisse M,Awandare GA,Soulama A,Tinto H,Hayette MP,Guiguemdé RT

更新日期：2017-01-23 00:00:00

abstract：BACKGROUND:In malaria-endemic areas, human populations are frequently exposed to immunomodulatory salivary components injected during mosquito blood feeding. The consequences on pathogen-specific immune responses are not well known. This study evaluated and compared the humoral responses specific to merozoite stage vac...

journal_title：Malaria journal

authors： Aka KG,Traoré DF,Sagna AB,Zoh DD,Assi SB,Tchiekoi BN,Adja AM,Remoue F,Poinsignon A

更新日期：2020-02-21 00:00:00

abstract：BACKGROUND:Chloroquine-resistant Plasmodium falciparum was first described in the Republic of Vanuatu in the early 1980s. In 1991, the Vanuatu Ministry of Health instituted new treatment guidelines for uncomplicated P. falciparum infection consisting of chloroquine/sulphadoxine-pyrimethamine combination therapy. Chloro...

journal_title：Malaria journal

authors： Kinzer MH,Chand K,Basri H,Lederman ER,Susanti AI,Elyazar I,Taleo G,Rogers WO,Bangs MJ,Maguire JD

更新日期：2010-04-06 00:00:00

abstract：:Following publication of the original article [1], one of the authors has highlighted an xml-related discrepancy concerning the author group titled 'Additional Tracking Resistance to Artemisinin Collaboration authors (TRAC Group Authorship)', listed under the Acknowledgements section. ...

journal_title：Malaria journal

authors： Srimuang K,Miotto O,Lim P,Fairhurst RM,Kwiatkowski DP,Woodrow CJ,Imwong M,Tracking Resistance to Artemisinin Collaboration.

更新日期：2018-09-10 00:00:00

abstract：BACKGROUND:Surveillance is a core component of an effective system to support malaria elimination. Poor surveillance data will prevent countries from monitoring progress towards elimination and targeting interventions to the last remaining at-risk places. An evaluation of the performance of surveillance systems in 16 c...

journal_title：Malaria journal

authors： Lourenço C,Tatem AJ,Atkinson PM,Cohen JM,Pindolia D,Bhavnani D,Le Menach A

更新日期：2019-09-18 00:00:00

abstract：BACKGROUND:The malaria vector Anopheles gambiae is polymorphic for chromosomal inversions on the right arm of chromosome 2 that segregate nonrandomly between assortatively mating populations in West Africa. One such inversion, 2Rj, is associated with the BAMAKO chromosomal form endemic to southern Mali and northern Gui...

journal_title：Malaria journal

authors： Coulibaly MB,Pombi M,Caputo B,Nwakanma D,Jawara M,Konate L,Dia I,Fofana A,Kern M,Simard F,Conway DJ,Petrarca V,della Torre A,Traoré S,Besansky NJ

更新日期：2007-10-01 00:00:00

abstract：:The sterile insect technique (SIT) has been shown to be an effective and sustainable genetic approach to control populations of selected major pest insects, when part of area-wide integrated pest management (AW-IPM) programmes. The technique introduces genetic sterility in females of the target population in the field...

journal_title：Malaria journal

authors： Robinson AS,Knols BG,Voigt G,Hendrichs J

更新日期：2009-11-16 00:00:00

abstract：BACKGROUND:Intermittent preventive (or presumptive) treatment of infants (IPTi), the administration of a curative anti-malarial dose to infants whether or not they are known to be infected, is being considered as a new strategy for malaria control. Five of the six trials using sulphadoxine-pyrimethamine (SP) for IPTi s...

journal_title：Malaria journal

authors： Gosling RD,Ghani AC,Deen JL,von Seidlein L,Greenwood BM,Chandramohan D

更新日期：2008-04-03 00:00:00

abstract：:After publication of the article [1], it has been brought to our attention that a funding acknowledgement has been omitted from the original article. The authors would like to include the following, "The study was undertaken as part of the Target Malaria consortium, which receives core funding from the Bill & Melinda ...

journal_title：Malaria journal

authors： Ogola E,Villinger J,Mabuka D,Omondi D,Orindi B,Mutunga J,Owino V,Masiga DK

更新日期：2017-09-19 00:00:00

abstract：BACKGROUND:Mass distribution campaigns of insecticide-treated nets for malaria prevention are usually accompanied by intensive behaviour change communication (BCC) to encourage hanging and use of nets. However, data on the effectiveness of these communication efforts are scarce. In preparation for the next round of mas...

journal_title：Malaria journal

authors： Kilian A,Lawford H,Ujuju CN,Abeku TA,Nwokolo E,Okoh F,Baba E

更新日期：2016-08-19 00:00:00

abstract：BACKGROUND:Recently, a real-time PCR assay known as photo-induced electron transfer (PET)-PCR which relies on self-quenching primers for the detection of Plasmodium spp. and Plasmodium falciparum was described. PET-PCR assay was found to be robust, and easier to use when compared to currently available real-time PCR me...

journal_title：Malaria journal

authors： Lucchi NW,Karell MA,Journel I,Rogier E,Goldman I,Ljolje D,Huber C,Mace KE,Jean SE,Akom EE,Oscar R,Buteau J,Boncy J,Barnwell JW,Udhayakumar V

更新日期：2014-11-26 00:00:00

abstract：BACKGROUND:When discussing the relationship between meteorological factors and malaria, previous studies mainly focus on the interaction between different climatic factors, while the possible interaction within one particular climatic predictor at different lag periods has been largely neglected. In this study, this is...

journal_title：Malaria journal

authors： Wu Y,Qiao Z,Wang N,Yu H,Feng Z,Li X,Zhao X

更新日期：2017-01-31 00:00:00

abstract：BACKGROUND:Individuals in a malaria endemic community differ from one another. Many of these differences, such as heterogeneities in transmission or treatment-seeking behaviour, affect malaria epidemiology. The different kinds of heterogeneity are likely to be correlated. Little is known about their impact on the shape...

journal_title：Malaria journal

authors： Ross A,Smith T

更新日期：2010-05-17 00:00:00

abstract：BACKGROUND:Long-lasting insecticidal nets (LLINs) are the primary malaria prevention and control intervention in many parts of sub-Saharan Africa. While LLINs are expected to last at least 3 years under normal use conditions, they can lose effectiveness because they fall out of use, are discarded, repurposed, physicall...

journal_title：Malaria journal

authors： Briet O,Koenker H,Norris L,Wiegand R,Vanden Eng J,Thackeray A,Williamson J,Gimnig JE,Fortes F,Akogbeto M,Yadouleton AW,Ombok M,Bayoh MN,Mzilahowa T,Abílio AP,Mabunda S,Cuamba N,Diouf E,Konaté L,Hamainza B,Katebe-S

更新日期：2020-08-28 00:00:00

abstract：BACKGROUND:The susceptibility of anopheline mosquito species to Plasmodium infection is known to be variable with some mosquitoes more permissive to infection than others. Little work, however, has been carried out investigating the susceptibility of major malaria vectors to geographically diverse tropical isolates of ...

journal_title：Malaria journal

authors： Hume JC,Tunnicliff M,Ranford-Cartwright LC,Day KP

更新日期：2007-10-24 00:00:00

abstract：BACKGROUND:Complex malaria infections are defined as those containing more than one genetically distinct lineage of Plasmodium parasite. Complexity of infection (COI) is a useful parameter to estimate from patient blood samples because it is associated with clinical outcome, epidemiology and disease transmission rate. ...

journal_title：Malaria journal

authors： Galinsky K,Valim C,Salmier A,de Thoisy B,Musset L,Legrand E,Faust A,Baniecki ML,Ndiaye D,Daniels RF,Hartl DL,Sabeti PC,Wirth DF,Volkman SK,Neafsey DE

更新日期：2015-01-19 00:00:00

abstract：BACKGROUND:Malaria remains a major human health problem, with no licensed vaccine currently available. Malaria infections initiate when infectious Plasmodium sporozoites are transmitted by Anopheline mosquitoes during their blood meal. Investigations of the malaria sporozoite are, therefore, of clear medical importance...

journal_title：Malaria journal

authors： Kennedy M,Fishbaugher ME,Vaughan AM,Patrapuvich R,Boonhok R,Yimamnuaychok N,Rezakhani N,Metzger P,Ponpuak M,Sattabongkot J,Kappe SH,Hume JC,Lindner SE

更新日期：2012-12-17 00:00:00

abstract：BACKGROUND:As in other countries of the Greater Mekong Sub-region (GMS), the private health sector constitutes a significant avenue where malaria services are provided and presents a unique opportunity for public-private collaboration. In September 2008, a public-private mix (PPM) strategy was launched initially in fou...

journal_title：Malaria journal

authors： Simmalavong N,Phommixay S,Kongmanivong P,Sichanthongthip O,Hongvangthong B,Gopinath D,Sintasath DM

更新日期：2017-11-13 00:00:00

abstract：BACKGROUND:Intravenous injection of mice with attenuated Plasmodium berghei sporozoites induces sterile immunity to challenge with viable sporozoites. Non-intravenous routes have been reported to yield poor immunity. Because intravenous immunization has been considered to be unacceptable for large scale vaccination of ...

journal_title：Malaria journal

authors： Voza T,Kebaier C,Vanderberg JP

更新日期：2010-12-15 00:00:00

abstract：BACKGROUND:Individual malaria interventions provide only partial protection in most epidemiological situations. Thus, there is a need to investigate whether combining interventions provides added benefit in reducing mortality and morbidity from malaria. The potential benefits of combining IPT in children (IPTc) with ho...

journal_title：Malaria journal

authors： Sesay S,Milligan P,Touray E,Sowe M,Webb EL,Greenwood BM,Bojang KA

更新日期：2011-01-07 00:00:00

abstract：BACKGROUND:Global efforts to address the burden of malaria have stagnated in recent years with malaria cases beginning to rise. Substandard and falsified anti-malarial treatments contribute to this stagnation. Poor quality anti-malarials directly affect health outcomes by increasing malaria morbidity and mortality, as ...

journal_title：Malaria journal

authors： Ozawa S,Evans DR,Higgins CR,Laing SK,Awor P

更新日期：2019-01-09 00:00:00

abstract：BACKGROUND:To date, human peripheral blood mononuclear cells (PBMCs) have been used mainly in immune stimulation assays and the interpretation of data can be influenced by the previous immunological history of donors and cross reactivity with other infectious agents. Resolving these limitations requires an alternative ...

journal_title：Malaria journal

authors： Chitsanoor S,Somsri S,Panburana P,Mungthin M,Ubalee R,Emyeam M,Jongwutiwes S,Sattabongkot J,Udomsangpetch R

更新日期：2017-03-27 00:00:00

abstract：:Artesunate (AS) is a clinically versatile artemisinin derivative utilized for the treatment of mild to severe malaria infection. Given the therapeutic significance of AS and the necessity of appropriate AS dosing, substantial research has been performed investigating the pharmacokinetics of AS and its active metabolit...

journal_title：Malaria journal

authors： Morris CA,Duparc S,Borghini-Fuhrer I,Jung D,Shin CS,Fleckenstein L

更新日期：2011-09-13 00:00:00

abstract：BACKGROUND:In insects, including Anopheles mosquitoes, Dscam (Down syndrome cell adhesion molecule) appears to be involved in phagocytosis of pathogens, and shows pathogen-specific splice-form expression between divergent pathogen (or parasite) types (e.g. between bacteria and Plasmodium or between Plasmodium berghei a...

journal_title：Malaria journal

authors： Smith PH,Mwangi JM,Afrane YA,Yan G,Obbard DJ,Ranford-Cartwright LC,Little TJ

更新日期：2011-06-08 00:00:00

abstract：BACKGROUND:Long-lasting insecticidal nets are an effective tool for malaria prevention, and "universal coverage" with such nets is increasingly the goal of national malaria control programmes. However, national level campaigns in several countries have run out of nets in the course of distribution, indicating a problem...

journal_title：Malaria journal

authors： Kilian A,Boulay M,Koenker H,Lynch M

更新日期：2010-11-18 00:00:00

abstract：BACKGROUND:Clinical profiling of two components for a synthetic peptide-based virosomal malaria vaccine has yielded promising results, encouraging the search for additional components for inclusion in a final multi-valent vaccine formulation. This report describes the immunological characterization of linear and cycliz...

journal_title：Malaria journal

authors： Tamborrini M,Mueller MS,Stoffel SA,Westerfeld N,Vogel D,Boato F,Zurbriggen R,Robinson JA,Pluschke G

更新日期：2009-12-30 00:00:00

abstract：BACKGROUND:In areas with ongoing malaria transmission, strategies to clear parasites from populations can reduce infection and transmission. The objective of this paper was to describe a malaria mass testing and treatment (MTAT) intervention implemented in six kebeles (villages) in Amhara Region, Ethiopia, at the begin...

journal_title：Malaria journal

authors： Scott CA,Yeshiwondim AK,Serda B,Guinovart C,Tesfay BH,Agmas A,Zeleke MT,Guesses GS,Ayenew AL,Workie WM,Steketee RW,Earle D,Bezabih B,Getachew A

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:The use of rapid diagnostic tests (RDTs) to diagnose malaria is common in sub-Saharan African laboratories, remote primary health facilities and in the community. Currently, there is a lack of reliable methods to ascertain health worker competency to accurately use RDTs in the testing and diagnosis of malari...

journal_title：Malaria journal

authors： Dorkenoo AM,Kouassi KC,Koura AK,Adams ML,Gbada K,Katawa G,Yakpa K,Charlebois R,Milgotina E,Merkel MO,Aidoo M

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:Artemisinin-based combination therapy is the first-line anti-malarial treatment for uncomplicated Plasmodium falciparum infection in Angola. To date, the prevalence of polymorphisms in the pfk13 gene, associated with artemisinin resistance, and pfmdr1, associated with lumefantrine resistance, have not been s...

journal_title：Malaria journal

authors： Ljolje D,Dimbu PR,Kelley J,Goldman I,Nace D,Macaia A,Halsey ES,Ringwald P,Fortes F,Udhayakumar V,Talundzic E,Lucchi NW,Plucinski MM

更新日期：2018-02-20 00:00:00