Correction to: Analysis of anti-malarial resistance markers in pfmdr1 and pfcrt across Southeast Asia in the Tracking Resistance to Artemisinin Collaboration.

abstract：BACKGROUND:Intermittent preventive treatment in pregnancy (IPTp) delivered during antenatal care (ANC) visits has been shown to be a highly efficacious and cost-effective intervention. Given the high rates of ANC attendance in sub-Saharan Africa, the current low IPTp coverage represents considerable missed opportunitie...

journal_title：Malaria journal

authors： Maheu-Giroux M,Castro MC

更新日期：2014-11-20 00:00:00

abstract：BACKGROUND:Patterns of decreasing malaria transmission intensity make presumptive treatment of malaria an unjustifiable approach in many African settings. The controlled use of anti-malarials after laboratory confirmed diagnosis is preferable in low endemic areas. Diagnosis may be facilitated by malaria rapid diagnosti...

journal_title：Malaria journal

authors： Bastiaens GJ,Schaftenaar E,Ndaro A,Keuter M,Bousema T,Shekalaghe SA

更新日期：2011-04-02 00:00:00

abstract：BACKGROUND:Recent progress in malaria control has caused renewed interest in mass drug administration (MDA) as a potential elimination strategy but the evidence base is limited. China has extensive experience with MDA, but it is not well documented. METHODS:An ecological study was conducted to describe the use of MDA ...

journal_title：Malaria journal

authors： Hsiang MS,Hwang J,Tao AR,Liu Y,Bennett A,Shanks GD,Cao J,Kachur SP,Feachem RG,Gosling RD,Gao Q

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:This paper reports on the availability of diagnostic tools and recommended anti-malarials in the 12-month period immediately following the implementation of a new national malaria treatment protocol (NMTP) in Papua New Guinea (PNG). Health worker adherence to the new NMTP is also examined and comparisons mad...

journal_title：Malaria journal

authors： Pulford J,Kurumop SF,Ura Y,Siba PM,Mueller I,Hetzel MW

更新日期：2013-11-27 00:00:00

abstract：BACKGROUND:Environmental temperature is an important driver of malaria transmission dynamics. Both the parasite and vector are sensitive to mean ambient temperatures and daily temperature variation. To understand transmission ecology, therefore, it is important to determine the range of microclimatic temperatures exper...

journal_title：Malaria journal

authors： Cator LJ,Thomas S,Paaijmans KP,Ravishankaran S,Justin JA,Mathai MT,Read AF,Thomas MB,Eapen A

更新日期：2013-03-02 00:00:00

abstract：BACKGROUND:Deltamethrin-impregnated, long-lasting insecticidal nets (LLINs) were distributed in the study area from November 2014 to January 2015 to evaluate their impact on malaria transmission in the presence of insecticide-resistant vectors. Studies were carried out in 16 selected clusters in Keshkal sub-district, C...

journal_title：Malaria journal

authors： Kona MP,Kamaraju R,Donnelly MJ,Bhatt RM,Nanda N,Chourasia MK,Swain DK,Suman S,Uragayala S,Kleinschmidt I,Pandey V

更新日期：2018-11-08 00:00:00

abstract：BACKGROUND:Prompt and effective malaria diagnosis not only alleviates individual suffering, but also decreases malaria transmission at the community level. The commonly used diagnostic methods, microscopy and rapid diagnostic tests, are usually insensitive at very low-density parasitaemia. Molecular techniques, on the ...

journal_title：Malaria journal

authors： Golassa L,Enweji N,Erko B,Aseffa A,Swedberg G

更新日期：2013-10-03 00:00:00

abstract：BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is currently a threat to malaria elimination due to risk of primaquine-induced haemolysis in G6PD deficient individuals. The World Health Organization (WHO) recommends G6PD screening before providing primaquine as a radical treatment against vivax malaria. ...

journal_title：Malaria journal

authors： Marasini B,Lal BK,Thapa S,Awasthi KR,Bajracharya B,Khanal P,Neupane S,Jha SN,Acharya S,Iama S,Koirala M,Koirala D,Bhandari S,Mahato RK,Chaudhary A,Ghimire P,Magar RG,Bhattarai RK,Gornsawun G,Penpitchaporn P,Bancon

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Tafenoquine is an 8-aminoquinoline being developed for radical cure (blood and liver stage elimination) of Plasmodium vivax. During monotherapy treatment, the compound exhibits slow parasite and fever clearance times, and toxicity in glucose-6-phosphate dehydrogenase (G6PD) deficiency is a concern. Combinati...

journal_title：Malaria journal

authors： Dow GS,Gettayacamin M,Hansukjariya P,Imerbsin R,Komcharoen S,Sattabongkot J,Kyle D,Milhous W,Cozens S,Kenworthy D,Miller A,Veazey J,Ohrt C

更新日期：2011-07-29 00:00:00

abstract：BACKGROUND:The intermittent screening and treatment (IST) of school children for malaria is one possible intervention strategy that could help reduce the burden of malaria among school children. Future implementation of IST will not only depend on its efficacy and cost-effectiveness but also on its acceptability to par...

journal_title：Malaria journal

authors： Okello G,Ndegwa SN,Halliday KE,Hanson K,Brooker SJ,Jones C

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:Transmission of malaria from man to mosquito depends on the presence of gametocytes, the sexual stage of Plasmodium parasites in the infected host. Naturally acquired antibodies against gametocytes exist and may play a role in controlling transmission by limiting the gametocyte development in the circulation...

journal_title：Malaria journal

authors： Gebru T,Ajua A,Theisen M,Esen M,Ngoa UA,Issifou S,Adegnika AA,Kremsner PG,Mordmüller B,Held J

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:Plasmodium falciparum merozoite antigens elicit antibody responses in malaria-endemic populations, some of which are clinically protective, which is one of the reasons why merozoite antigens are the focus of malaria vaccine development efforts. Polymorphisms in several merozoite antigen-encoding genes are th...

journal_title：Malaria journal

authors： Ochola-Oyier LI,Okombo J,Wagatua N,Ochieng J,Tetteh KK,Fegan G,Bejon P,Marsh K

更新日期：2016-05-06 00:00:00

abstract：:This meeting report presents the key findings and discussion points of a 1-day meeting entitled 'Fake anti-malarials: start with the facts' held on 28th May 2015, in Geneva, Switzerland, to disseminate the findings of the artemisinin combination therapy consortium's drug quality programme. The teams purchased over 10,...

journal_title：Malaria journal

authors： Kaur H,Clarke S,Lalani M,Phanouvong S,Guérin P,McLoughlin A,Wilson BK,Deats M,Plançon A,Hopkins H,Miranda D,Schellenberg D

更新日期：2016-02-13 00:00:00

abstract：:The sterile insect technique (SIT) has been shown to be an effective and sustainable genetic approach to control populations of selected major pest insects, when part of area-wide integrated pest management (AW-IPM) programmes. The technique introduces genetic sterility in females of the target population in the field...

journal_title：Malaria journal

authors： Robinson AS,Knols BG,Voigt G,Hendrichs J

更新日期：2009-11-16 00:00:00

abstract：BACKGROUND:Within the context of increasing antimalarial costs and or decreasing malaria transmission, the importance of limiting antimalarial treatment to only those confirmed as having malaria parasites becomes paramount. This motivates for this assessment of the cost-effectiveness of routine use of rapid diagnostic ...

journal_title：Malaria journal

authors： Zikusooka CM,McIntyre D,Barnes KI

更新日期：2008-09-15 00:00:00

abstract：BACKGROUND:In Plasmodium, the high level of genetic diversity and the interactions established by co-infecting parasite populations within the same host may be a source of selection on pathogen virulence and drug resistance. As different patterns have already been described in humans and mosquitoes, parasite diversity ...

journal_title：Malaria journal

authors： Mendes C,Salgueiro P,Gonzalez V,Berzosa P,Benito A,do Rosário VE,de Sousa B,Cano J,Arez AP

更新日期：2013-03-27 00:00:00

abstract：BACKGROUND:The United Nation's sustainable development goal for 2030 is to eradicate the global malaria epidemic, primarily as the disease continues to be one of the major concerns for public health in sub-Saharan Africa. In 2015, the region accounted for 90% of malaria deaths. Mozambique recorded a malaria mortality r...

journal_title：Malaria journal

authors： Ferrão JL,Mendes JM,Painho M,Zacarias S

更新日期：2017-05-22 00:00:00

abstract：BACKGROUND:Very few data on anti-malarial efficacy are available from the Democratic Republic of Congo (DRC). DRC changed its anti-malarial treatment policy to amodiaquine (AQ) and artesunate (AS) in 2005. METHODS:The results of two in vivo efficacy studies, which tested AQ and sulphadoxine-pyrimethamine (SP) monother...

journal_title：Malaria journal

authors： Bonnet M,Broek Iv,van Herp M,Urrutia PP,van Overmeir C,Kyomuhendo J,Ndosimao CN,Ashley E,Guthmann JP

更新日期：2009-08-10 00:00:00

abstract：BACKGROUND:The recent reports on the decreasing susceptibility of Plasmodium falciparum to artemisinin derivatives along the Thailand and Myanmar border are worrying. Indeed it may spread to India and then Africa, repeating the same pattern observed for chloroquine resistance. Therefore, it is essential to start monito...

journal_title：Malaria journal

authors： Tinto H,Bonkian LN,Nana LA,Yerbanga I,Lingani M,Kazienga A,Valéa I,Sorgho H,Kpoda H,Guiguemdé TR,Ouédraogo JB,Mens PF,Schallig H,D'Alessandro U

更新日期：2014-05-31 00:00:00

abstract：BACKGROUND:Malaria is known as tazo or tazomoka in local terminology in Madagascar. Within the context of traditional practice, malaria (and/or malaria symptoms) is commonly treated by decoctions or infusions from bitter plants. One possible approach to the identification of new antimalarial drug candidates is to searc...

journal_title：Malaria journal

authors： Randrianarivelojosia M,Rasidimanana VT,Rabarison H,Cheplogoi PK,Ratsimbason M,Mulholland DA,Mauclère P

更新日期：2003-07-24 00:00:00

abstract：BACKGROUND:Several anti-malarial drugs are associated with adverse cardiovascular effects. These effects may be exacerbated when different anti-malarials are used in combination. There has been no report yet on the potential cardiac effects of the combination artesunate-amodiaquine. METHODS:Electrocardiographic (ECG) ...

journal_title：Malaria journal

authors： Adjei GO,Oduro-Boatey C,Rodrigues OP,Hoegberg LC,Alifrangis M,Kurtzhals JA,Goka BQ

更新日期：2012-12-17 00:00:00

abstract：BACKGROUND:Malaria prevention has remained a critical area in the absence of efficacious vaccines against malaria. Drugs currently used as chemotherapeutics are also used in chemoprophylaxis increasing possible drug resistance. Asiatic acid is a natural phytochemical with oxidant, antioxidant and anti-inflammatory prop...

journal_title：Malaria journal

authors： Mavondo GA,Mkhwananzi BN,Mabandla MV

更新日期：2016-04-21 00:00:00

abstract：BACKGROUND:Rosette-formation of Plasmodium falciparum parasitized erythrocytes is of importance in the development of severe malaria. The parasite-derived molecule PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1), central to rosetting, is suggested to be included in a multimeric vaccine targeting severe di...

journal_title：Malaria journal

authors： Angeletti D,Albrecht L,Wahlgren M,Moll K

更新日期：2013-01-24 00:00:00

abstract：BACKGROUND:In 2009, Santa Isabel Province in the Solomon Islands embarked on a malaria elimination programme. However, very little is known in the Province about the anopheline fauna, which species are vectors, their bionomics and how they may respond to intensified intervention measures. The purpose of this study was ...

journal_title：Malaria journal

authors： Bugoro H,Iro'ofa C,Mackenzie DO,Apairamo A,Hevalao W,Corcoran S,Bobogare A,Beebe NW,Russell TL,Chen CC,Cooper RD

更新日期：2011-09-30 00:00:00

abstract：BACKGROUND:Most rapid diagnostic tests (RDTs) currently used for malaria diagnosis cannot distinguish the various Plasmodium infections. The development of a Plasmodium vivax specific RDTs with high sensitivity to sufficiently differentiate the two most common Plasmodium infections would be very crucial for disease tre...

journal_title：Malaria journal

authors： Dzakah EE,Kang K,Ni C,Wang H,Wu P,Tang S,Wang J,Wang J,Wang X

更新日期：2013-06-12 00:00:00

abstract：BACKGROUND:Convulsions is one of the key signs of severe malaria among children under five years of age, potentially leading to serious complications or death. Several studies of care-seeking behaviour have revealed that local illness concepts linked to convulsions (referred to as degedege in Tanzanian Kiswahili) calle...

journal_title：Malaria journal

authors： Dillip A,Hetzel MW,Gosoniu D,Kessy F,Lengeler C,Mayumana I,Mshana C,Mshinda H,Schulze A,Makemba A,Pfeiffer C,Weiss MG,Obrist B

更新日期：2009-06-29 00:00:00

abstract：BACKGROUND:Extensive genetic diversity in the Plasmodium falciparum circumsporozoite protein (PfCSP) is a major contributing factor to the moderate efficacy of the RTS,S/AS01 vaccine. The transmission intensity and rates of recombination within and between populations influence the extent of its genetic diversity. Unde...

journal_title：Malaria journal

authors： Amegashie EA,Amenga-Etego L,Adobor C,Ogoti P,Mbogo K,Amambua-Ngwa A,Ghansah A

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:The effects that artemether-lumefantrine (AL) has on gametocyte dynamics in the short-term have recently been described. However there is limited long-term longitudinal data on the effect of AL on gametocyte dynamics in asymptomatic children. METHODS:An epidemiological study was conducted in Kombewa, Wester...

journal_title：Malaria journal

authors： Andagalu B,Mativo J,Kamau E,Ogutu B

更新日期：2014-07-09 00:00:00

abstract：BACKGROUND:Congenital malaria is the direct infection of an infant with malaria parasites from their mother prior to or during birth. Neonatal malaria is due to an infective mosquito bite after birth. Neonatal and congenital malaria (NCM) are potentially life-threatening conditions that are believed to occur at relativ...

journal_title：Malaria journal

authors： Olupot-Olupot P,Eregu EIE,Naizuli K,Ikiror J,Acom L,Burgoine K

更新日期：2018-04-20 00:00:00

abstract：BACKGROUND:Sulfadoxine-pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis and is considered for programmes in the Democratic Republic of Congo (DRC). However, SP efficacy is threatened by drug resistance, that is conferred by mutations in the dhfr and dhps genes. The World Health Organization has specified...

journal_title：Malaria journal

authors： van Lenthe M,van der Meulen R,Lassovski M,Ouabo A,Bakula E,Badio C,Cibenda D,Okell L,Piriou E,Grignard L,Lanke K,Rao B,Bousema T,Roper C

更新日期：2019-12-18 00:00:00