G6PD deficiency in malaria endemic areas of Nepal.

abstract：BACKGROUND:Several public health interventions to improve management of patients with fever are largely focused on the public sector yet a high proportion of patients seek care outside the formal healthcare sector. Few studies have provided information on the determinants of utilization of the private sector as against...

journal_title：Malaria journal

authors： Ansah EK,Gyapong M,Narh-Bana S,Bart-Plange C,Whitty CJ

更新日期：2016-05-25 00:00:00

abstract：:Recent WHO guidelines recommend a universal "test and treat" strategy for malaria, mainly by use of rapid diagnostic test (RDT) in all areas. The evidence for this approach is questioned here as there is a risk of over-reliance on parasitological diagnosis in high transmission situations, which still exist. In such ar...

journal_title：Malaria journal

authors： Graz B,Willcox M,Szeless T,Rougemont A

更新日期：2011-05-20 00:00:00

abstract：BACKGROUND:Malaria is an increasing concern in Indonesia. Socio-demographic factors were found to strongly influence malaria prevalence. This research aimed to explore the associations between socio-demographic factors and malaria prevalence in Indonesia. METHODS:The study used a cross-sectional design and analysed re...

journal_title：Malaria journal

authors： Hasyim H,Dale P,Groneberg DA,Kuch U,Müller R

更新日期：2019-04-12 00:00:00

abstract：BACKGROUND:Insecticide-treated bed nets (ITN) have been shown to be efficacious in reducing malaria morbidity and mortality in many regions. Unfortunately in some areas, malaria has persisted despite the scale up of ITNs. Recent reports indicate that human behaviour and mosquito behaviour are potential threats to the e...

journal_title：Malaria journal

authors： Mangeni JN,Menya D,Obala A,Platt A,O'Meara WP

更新日期：2016-11-08 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) signalling is reported to be primed by the infection of human malaria parasite, Plasmodium falciparum. However, little is known about the regulation of macrophages TLR signalling by the infection of lethal or non-lethal strain of rodent malaria parasites. METHODS:BALB/c mice were ...

journal_title：Malaria journal

authors： Fu Y,Ding Y,Zhou T,Fu X,Xu W

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Ensuring the quality of malaria medicines is crucial in working toward malaria control and eventual elimination. Unlike other validated tests that can assess all critical quality attributes, which is the standard for determining the quality of medicines, basic tests are significantly less expensive, faster, ...

journal_title：Malaria journal

authors： Pribluda VS,Barojas A,Añez A,López CG,Figueroa R,Herrera R,Nakao G,Nogueira FH,Pianetti GA,Povoa MM,Viana GM,Gomes MS,Escobar JP,Sierra OL,Norena SP,Veloz R,Bravo MS,Aldás MR,Hindssemple A,Collins M,Ceron N,Kris

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Malaria control largely depends on availability of highly efficacious drugs, however, over the years, has been threatened by emergence of drug resistance. It is, therefore, important to monitor the impact of recurrent anti-malarial treatment on the long-term efficacy of anti-malarial regimens, especially in ...

journal_title：Malaria journal

authors： Byakika-Kibwika P,Nyakato P,Lamorde M,Kiragga AN

更新日期：2018-10-30 00:00:00

abstract：BACKGROUND:Mice with genetic deficiencies in adaptive immunity are used for the grafting of human cells or pathogens, to study human diseases, however, the innate immune responses to xenografts in these mice has received little attention. Using the NOD/SCID Plasmodium falciparum mouse model an analysis of innate defenc...

journal_title：Malaria journal

authors： Arnold L,Tyagi RK,Mejia P,Van Rooijen N,Pérignon JL,Druilhe P

更新日期：2010-07-09 00:00:00

abstract：BACKGROUND:Sulphadoxine-pyrimethamine (SP) has been in use for the treatment of uncomplicated falciparum malaria in Malaysia since the 1970s and is still widely employed in spite of widespread clinical resistance. Resistance to SP is known to be mediated by mutations in the pfdhfr and pfdhps genes. The aim of the prese...

journal_title：Malaria journal

authors： Abdullah NR,Norahmad NA,Jelip J,Sulaiman LH,Mohd Sidek H,Ismail Z,Noedl H

更新日期：2013-06-12 00:00:00

abstract：BACKGROUND:Indonesia is home to a variety of malaria vectors whose specific bionomic traits remain largely uncharacterized. Species-specific behaviours, such as host feeding preferences, impact the dynamics of malaria transmission and the effectiveness of vector control interventions. METHODS:To examine species-specif...

journal_title：Malaria journal

authors： St Laurent B,Burton TA,Zubaidah S,Miller HC,Asih PB,Baharuddin A,Kosasih S,Shinta,Firman S,Hawley WA,Burkot TR,Syafruddin D,Sukowati S,Collins FH,Lobo NF

更新日期：2017-08-02 00:00:00

abstract：BACKGROUND:The sulphadoxine/pyrimethamine (SDX/PYR) combination had been chosen to treat uncomplicated falciparum malaria in Malaysia for more than 30 years. Non-silent mutations in dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes are responsible for the resistance to pyrimethamine and sulphadox...

journal_title：Malaria journal

authors： Lau TY,Sylvi M,William T

更新日期：2013-12-10 00:00:00

abstract：BACKGROUND:Indoor-based anti-vector interventions remain the preferred means of reducing risk of malaria transmission in malaria endemic areas around the world. Despite demonstrated success in reducing human-mosquito interactions, these methods are effective solely against endophilic vectors. It may be that outdoor loc...

journal_title：Malaria journal

authors： Reddy MR,Overgaard HJ,Abaga S,Reddy VP,Caccone A,Kiszewski AE,Slotman MA

更新日期：2011-07-07 00:00:00

abstract：BACKGROUND:There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to determine the diagnostic accuracy of the NanoRam(®), a handheld Raman spectrometer (RS), to identify anti-malarial drugs. METHODS:In total, 289 anti-malarial d...

journal_title：Malaria journal

authors： Visser BJ,de Vries SG,Bache EB,Meerveld-Gerrits J,Kroon D,Boersma J,Agnandji ST,van Vugt M,Grobusch MP

更新日期：2016-03-15 00:00:00

abstract：BACKGROUND:Falciparum malaria remains a major occupational illness that accounts for several deaths per year and numerous lost working days among the expatriate population, working or living in high-risk malarious areas. Compliance to preventive strategies is poor in travellers, especially business travellers, expatria...

journal_title：Malaria journal

authors： Roukens AH,Berg J,Barbey A,Visser LG

更新日期：2008-07-14 00:00:00

abstract：BACKGROUND:Immunization with attenuated malaria sporozoites protects humans from experimental malaria challenge by mosquito bite. Protection in humans is strongly correlated with the production of T cells targeting a heterogeneous population of pre-erythrocyte antigen proteoforms, including liver stage antigens. Curren...

journal_title：Malaria journal

authors： Winer B,Edgel KA,Zou X,Sellau J,Hadiwidjojo S,Garver LS,McDonough CE,Kelleher NL,Thomas PM,Villasante E,Ploss A,Gerbasi VR

更新日期：2020-01-07 00:00:00

abstract：BACKGROUND:DNA microarrays have been a valuable tool in malaria research for over a decade but remain in limited use in part due their relatively high cost, poor availability, and technical difficulty. With the aim of alleviating some of these factors next-generation DNA microarrays for genome-wide transcriptome analys...

journal_title：Malaria journal

authors： Kafsack BF,Painter HJ,Llinás M

更新日期：2012-06-08 00:00:00

abstract：:The incidence and mortality of COVID-19, according to the World Health Organization reports, shows a noticeable difference between North America, Western Europe, and South Asia on one hand and most African countries on the other hand, especially the malaria-endemic countries. Although this observation could be attribu...

journal_title：Malaria journal

authors： Hussein MIH,Albashir AAD,Elawad OAMA,Homeida A

更新日期：2020-12-23 00:00:00

abstract：BACKGROUND:Insecticide-treated nets (ITNs) are losing efficacy against pyrethroid-resistant malaria vector populations throughout Africa. Safeguarding bed net efficacy, vital for effective malaria control, requires greater knowledge of mosquito-ITN interactions and how this impacts on the mosquito. METHODS:A purpose-b...

journal_title：Malaria journal

authors： Hughes A,Foster GM,Guy A,Matope A,Abe M,Towers D,McCall PJ

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:In order to sustain the gains achieved by current malaria control strategies, robust surveillance systems that monitor dynamics of vectors and their roles in malaria transmission over time are essential. This longitudinal study demonstrates the trends in malaria vector dynamics and their relative contributio...

journal_title：Malaria journal

authors： Lwetoijera DW,Harris C,Kiware SS,Dongus S,Devine GJ,McCall PJ,Majambere S

更新日期：2014-08-24 00:00:00

abstract：BACKGROUND:Surveillance is a core component of an effective system to support malaria elimination. Poor surveillance data will prevent countries from monitoring progress towards elimination and targeting interventions to the last remaining at-risk places. An evaluation of the performance of surveillance systems in 16 c...

journal_title：Malaria journal

authors： Lourenço C,Tatem AJ,Atkinson PM,Cohen JM,Pindolia D,Bhavnani D,Le Menach A

更新日期：2019-09-18 00:00:00

abstract：BACKGROUND:This paper reports on the availability of diagnostic tools and recommended anti-malarials in the 12-month period immediately following the implementation of a new national malaria treatment protocol (NMTP) in Papua New Guinea (PNG). Health worker adherence to the new NMTP is also examined and comparisons mad...

journal_title：Malaria journal

authors： Pulford J,Kurumop SF,Ura Y,Siba PM,Mueller I,Hetzel MW

更新日期：2013-11-27 00:00:00

abstract：BACKGROUND:The present study evaluated the SD Bioline Malaria Ag 05FK40 (SDFK40), a three-band RDT detecting Plasmodium falciparum-specific parasite lactate dehydrogenase (Pf-pLDH) and pan Plasmodium-specific pLDH (pan-pLDH), in a reference setting. METHODS:The SDFK40 was retrospectively and prospectively tested again...

journal_title：Malaria journal

authors： Maltha J,Gillet P,Cnops L,Bottieau E,Van Esbroeck M,Bruggeman C,Jacobs J

更新日期：2011-01-12 00:00:00

abstract：BACKGROUND:Malaria remains the most important public health problem in tropical and subtropical areas. Mothers' or caregivers' ability to recognize childhood malaria-related morbidity is crucial as knowledge, attitudes and health seeking behavior of caregivers towards childhood malaria could influence response to signs...

journal_title：Malaria journal

authors： Yewhalaw D,Kassahun W,Woldemichael K,Tushune K,Sudaker M,Kaba D,Duchateau L,Van Bortel W,Speybroeck N

更新日期：2010-02-11 00:00:00

abstract：BACKGROUND:Although it is well known that drug pressure selects for drug-resistant parasites, the role of transmission reduction by insecticide-treated bed nets (ITNs) on drug resistance remains unclear. In this study, the drug resistance profile of current and previous first-line anti-malarials in Kenya was assessed w...

journal_title：Malaria journal

authors： Shah M,Omosun Y,Lal A,Odero C,Gatei W,Otieno K,Gimnig JE,ter Kuile F,Hawley WA,Nahlen B,Kariuki S,Walker E,Slutsker L,Hamel M,Shi YP

更新日期：2015-02-14 00:00:00

abstract：BACKGROUND:Malaria is one of the most severe global public health problems worldwide, particularly in Africa, where Nigeria has the greatest number of malaria cases. This community-based study was designed to investigate the prevalence and risk factors of malaria and to evaluate the knowledge, attitudes, and practices ...

journal_title：Malaria journal

authors： Dawaki S,Al-Mekhlafi HM,Ithoi I,Ibrahim J,Atroosh WM,Abdulsalam AM,Sady H,Elyana FN,Adamu AU,Yelwa SI,Ahmed A,Al-Areeqi MA,Subramaniam LR,Nasr NA,Lau YL

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:Intravenous injection of mice with attenuated Plasmodium berghei sporozoites induces sterile immunity to challenge with viable sporozoites. Non-intravenous routes have been reported to yield poor immunity. Because intravenous immunization has been considered to be unacceptable for large scale vaccination of ...

journal_title：Malaria journal

authors： Voza T,Kebaier C,Vanderberg JP

更新日期：2010-12-15 00:00:00

abstract：BACKGROUND:Increases in the coverage of long-lasting insecticidal nets (LLINs) have significantly reduced the abundance of Anopheles gambiae sensu stricto in several African settings, leaving its more zoophagic sibling species Anopheles arabiensis as the primary vector. This study investigated the impact of livestock o...

journal_title：Malaria journal

authors： Mayagaya VS,Nkwengulila G,Lyimo IN,Kihonda J,Mtambala H,Ngonyani H,Russell TL,Ferguson HM

更新日期：2015-01-21 00:00:00

abstract：BACKGROUND:Plasmodium ovale, considered the rarest of the malaria parasites of humans, consists of two morphologically identical but genetically distinct sympatric species, Plasmodium ovale curtisi and Plasmodium ovale wallikeri. These parasites resemble morphologically to Plasmodium vivax with which they also share a ...

journal_title：Malaria journal

authors： Chavatte JM,Tan SB,Snounou G,Lin RT

更新日期：2015-11-14 00:00:00

abstract：BACKGROUND:In insects, including Anopheles mosquitoes, Dscam (Down syndrome cell adhesion molecule) appears to be involved in phagocytosis of pathogens, and shows pathogen-specific splice-form expression between divergent pathogen (or parasite) types (e.g. between bacteria and Plasmodium or between Plasmodium berghei a...

journal_title：Malaria journal

authors： Smith PH,Mwangi JM,Afrane YA,Yan G,Obbard DJ,Ranford-Cartwright LC,Little TJ

更新日期：2011-06-08 00:00:00

abstract：BACKGROUND:Community-based service delivery is vital to the effectiveness, affordability and sustainability of vector control generally, and to labour-intensive larval source management (LSM) programmes in particular. CASE DESCRIPTION:The institutional evolution of a city-level, community-based LSM programme over 14 y...

journal_title：Malaria journal

authors： Chaki PP,Kannady K,Mtasiwa D,Tanner M,Mshinda H,Kelly AH,Killeen GF

更新日期：2014-06-25 00:00:00