Abstract:
BACKGROUND:Malaria remains the most important public health problem in tropical and subtropical areas. Mothers' or caregivers' ability to recognize childhood malaria-related morbidity is crucial as knowledge, attitudes and health seeking behavior of caregivers towards childhood malaria could influence response to signs of the disease. METHODS:A total of 1,003 caregivers in 'at-risk' villages in close proximity to the Gilgel-Gibe hydroelectric dam in south-western Ethiopia, and 953 caregivers in 'control' villages further away from the dam were surveyed using structured questionnaires to assess their knowledge, perceptions and health seeking behaviour about childhood malaria. RESULTS:Malaria (busa) was ranked as the most serious health problem. Caregivers perceived childhood malaria as a preventable ('at-risk' 96%, 'control' 86%) and treatable ('at-risk' 98% and 'control' 96%) disease. Most caregivers correctly associated the typical clinical manifestations with malaria attacks. The use of insecticide-treated nets (ITNs) was mentioned as a personal protective measure, whereas the role of indoor residual spraying (IRS) in malaria prevention and control was under-recognized. Most of the caregivers would prefer to seek treatment in health-care services in the event of malaria and reported the use of recommended anti-malarials. CONCLUSION:Health education to improve knowledge, perceptions and health-seeking behaviour related to malaria is equally important for caregivers in 'at risk' villages and caregivers in 'control' villages as minimal differences seen between both groups. Concluding, there may be a need of more than one generation after the introduction of the dam before differences can be noticed. Secondly, differences in prevalence between 'control' and 'at-risk' villages may not be sufficient to influence knowledge and behaviour.
journal_name
Malar Jjournal_title
Malaria journalauthors
Yewhalaw D,Kassahun W,Woldemichael K,Tushune K,Sudaker M,Kaba D,Duchateau L,Van Bortel W,Speybroeck Ndoi
10.1186/1475-2875-9-47subject
Has Abstractpub_date
2010-02-11 00:00:00pages
47issn
1475-2875pii
1475-2875-9-47journal_volume
9pub_type
杂志文章相关文献
MALARIA JOURNAL文献大全abstract:BACKGROUND:Iron deficiency is the most widespread nutrient deficiency and an important cause of developmental impairment in children. However, some studies have indicated that iron deficiency can also protect against malaria, which is a leading cause of childhood morbidity and mortality in large parts of the world. Thi...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2186-8
更新日期:2018-01-16 00:00:00
abstract:BACKGROUND:The production and use of malaria rapid diagnostic tests (RDTs) has risen dramatically over the past 20 years. In view of weak or non-existing in vitro diagnostics (IVD) regulations and post-marketing surveillance (PMS) systems in malaria endemic countries, the World Health Organization, later joined by the ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-020-03324-3
更新日期:2020-07-13 00:00:00
abstract:BACKGROUND:Saglin, a 100 kDa protein composed of two 50 kDa homodimers, is present in the salivary glands of Anopheles gambiae and has been considered an essential receptor for sporozoites (SPZ) of Plasmodium berghei and Plasmodium falciparum (Pf), allowing SPZ to recognize, bind to, and infect mosquito salivary glands...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2634-5
更新日期:2019-01-03 00:00:00
abstract:BACKGROUND:Between 2007 and 2013, the Tanzanian public sector received 93.1 million doses of first-line anti-malarial artemisinin-based combination therapy (ACT) in the form of artemether-lumefantrine entirely supplied by funding partners. The introduction of a health facility ACT stock monitoring system using SMS tech...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-181
更新日期:2014-05-11 00:00:00
abstract::The Rethinking Malaria Leadership Forum, held at Harvard Business School in February 2017 with collaboration of the Barcelona Institute for Global Health and the Swiss Tropical and Public Health Institute, identified this training gap as a high priority for both analysis and action. The gap in human resource training ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2199-3
更新日期:2018-01-25 00:00:00
abstract:BACKGROUND:Policy makers, governments and donors are faced with an information gap when considering ways to improve access to artemisinin-based combination therapy (ACT) and malaria diagnostics including rapid diagnostic tests (RDTs). To help address some of these gaps, a five-year multi-country research project called...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-10-325
更新日期:2011-10-31 00:00:00
abstract::BACKGROUND: In areas of high-level, year-round malaria transmission, morbidity and mortality due to malaria decrease after the first two to three years of life. This reduction may be related to the development of cellular immunity to specific antigens expressed in the different life-cycle stages of Plasmodium falcipar...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-2-37
更新日期:2003-11-05 00:00:00
abstract:BACKGROUND:Tumour necrosis factor (TNF) and interferon gamma (IFN-γ), encoded by TNF-836 C/A (rs 1800630) and IFN-γ -1616 C/T (rs2069705) genes, are key immunological mediators that are believed to both play protective and pathological roles in malaria. The aim of this study was to investigate the relationship between ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-314
更新日期:2014-08-13 00:00:00
abstract:BACKGROUND:Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmodium vivax malaria whe...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-016-1443-y
更新日期:2016-07-22 00:00:00
abstract:BACKGROUND:There is an urgent need to develop and test novel compounds against malaria infection. Carrageenans, sulphated polysaccharides derived from seaweeds, have been previously shown to inhibit Plasmodium falciparum in vitro. However, they are inflammatory and alter the permeability of the blood-brain barrier, rai...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-487
更新日期:2014-12-11 00:00:00
abstract:BACKGROUND:Malaria is heterogeneously distributed across landscapes. Human population movement (HPM) could link sub-regions with varying levels of transmission, leading to the persistence of disease even in very low transmission settings. Malaria along the Thai-Myanmar border has been decreasing, but remains heterogene...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-019-2704-3
更新日期:2019-03-08 00:00:00
abstract:BACKGROUND:Recent progress in malaria control has caused renewed interest in mass drug administration (MDA) as a potential elimination strategy but the evidence base is limited. China has extensive experience with MDA, but it is not well documented. METHODS:An ecological study was conducted to describe the use of MDA ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-12-383
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:With an Annual Parasite Incidence (API) of 132.1, in the high and moderate risks zones, the Maroni area of French Guiana has the second highest malaria incidence of South-America after Guyana (API = 183.54) and far above Brazil (API = 28.25). Malaria transmission is occurring despite strong medical assistanc...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-9-80
更新日期:2010-03-22 00:00:00
abstract:BACKGROUND:Malaria caused by Plasmodium falciparum in pregnancy can result in adverse maternal and fetal sequelae. This review evaluated the adherence of the national guidelines drawn from World Health Organization (WHO) regions, Africa, Eastern Mediterranean, Southeast Asia, and Western Pacific, to the WHO recommendat...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/s12936-020-03565-2
更新日期:2021-01-23 00:00:00
abstract:BACKGROUND:Malaria transmission is strongly determined by the environmental temperature and the environment is rarely constant. Therefore, mosquitoes and parasites are not only exposed to the mean temperature, but also to daily temperature variation. Recently, both theoretical and laboratory work has shown, in addition...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-192
更新日期:2014-05-27 00:00:00
abstract::The classic formulae in malaria epidemiology are reviewed that relate entomological parameters to malaria transmission, including mosquito survivorship and age-at-infection, the stability index (S), the human blood index (HBI), proportion of infected mosquitoes, the sporozoite rate, the entomological inoculation rate ...
journal_title:Malaria journal
pub_type: 杂志文章,评审
doi:10.1186/1475-2875-3-13
更新日期:2004-06-04 00:00:00
abstract:BACKGROUND:Despite some problems related to accuracy and applicability, malaria rapid diagnostic tests (RDTs), are currently considered the best option in areas with limited laboratory services for improving case management and reducing over-treatment. However, their performance must be established taking into the acco...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-224
更新日期:2012-07-06 00:00:00
abstract:BACKGROUND:Mosquito transgenesis offers new promises for the genetic control of vector-borne infectious diseases such as malaria and dengue fever. Genetic control strategies require the release of large number of male mosquitoes into field populations, whether they are based on the use of sterile males (sterile insect ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-11-302
更新日期:2012-08-28 00:00:00
abstract:BACKGROUND:Defining the number and location of sprayable structures (houses) is foundational to plan and monitor indoor residual spray (IRS) implementation, a primary intervention used to control the transmission of malaria. Only by mapping the location and type of all sprayable structures can IRS operations be planned...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-015-0831-z
更新日期:2015-09-17 00:00:00
abstract:BACKGROUND:There is growing concern that malaria vector resistance to pyrethroid insecticides may reduce the effectiveness of long-lasting insecticidal nets (LLINs). Combination LLINs are designed to control susceptible and pyrethroid-resistant mosquito populations through a mixture of pyrethroid with piperonyl butoxid...
journal_title:Malaria journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12936-017-2124-1
更新日期:2017-11-21 00:00:00
abstract:BACKGROUND:Polyclonal B-cell activation is well known to occur in Plasmodium infections, but its role in pathogenesis or protection remains unclear. However, protective properties of natural antibodies have previously been demonstrated in other contexts. METHODS:Sera from asymptomatic and symptomatic Plasmodium-infect...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-4-5
更新日期:2005-01-20 00:00:00
abstract:BACKGROUND:Malaria is a notifiable disease in the Netherlands, a non-endemic country. Imported malaria infections occur regularly among travellers, migrants and visitors. Surveillance data were analysed from 2008 to 2015. Trends in amounts of notifications among risk groups were analysed using Poisson regression. For a...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1711-5
更新日期:2017-02-02 00:00:00
abstract:BACKGROUND:The role of the liver for survival of blood-stage malaria is only poorly understood. In experimental blood-stage malaria with Plasmodium chabaudi, protective vaccination induces healing and, thus, survival of otherwise lethal infections. This model is appropriate to study the role of the liver in vaccination...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2366-6
更新日期:2018-05-29 00:00:00
abstract:BACKGROUND:Hypoglycaemia is a poor prognostic indicator in severe malaria. Intravenous infusions are rarely feasible in rural areas. The efficacy of sublingual sugar (SLS) was assessed in a pilot randomized controlled trial among hypoglycaemic children with severe malaria in Mali. METHODS:Of 151 patients with presumed...
journal_title:Malaria journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2875-7-242
更新日期:2008-11-23 00:00:00
abstract:BACKGROUND:Shandong Province experienced a declining malaria trend of local-acquired transmission, but the increasing imported malaria remains a challenge. Therefore, understanding the epidemiological characteristics of malaria and the control and elimination strategy and interventions is needed for better planning to ...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-017-1708-0
更新日期:2017-01-31 00:00:00
abstract:BACKGROUND:Resistance of Plasmodium falciparum to anti-malarial drugs has hampered efforts to eradicate malaria. Recent reports of a decline in the prevalence of chloroquine-resistant P. falciparum in several countries, including Malawi and Zambia, is raising the hope of reintroducing chloroquine in the near future, id...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/s12936-018-2551-7
更新日期:2018-11-07 00:00:00
abstract:BACKGROUND:Surveillance for drug-resistant Plasmodium falciparum should be a component of malaria control programmes. Real-time PCR methods for the detection of parasite single-nucleotide polymorphisms (SNPs) and gene amplification could be useful survellance tools. METHODS:A real-time PCR assay has been developed tha...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-3-9
更新日期:2004-05-07 00:00:00
abstract:BACKGROUND:Malaria and schistosomiasis are endemic and co-exist in the same geographic areas, even co-infecting the same host. Previous studies have reported that concomitant infection with Schistosoma japonicum could offer protection against experimental cerebral malaria (ECM) in mice. This study was performed to eval...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-116
更新日期:2014-03-26 00:00:00
abstract:BACKGROUND:Intermittent preventive treatment in pregnancy (IPTp) delivered during antenatal care (ANC) visits has been shown to be a highly efficacious and cost-effective intervention. Given the high rates of ANC attendance in sub-Saharan Africa, the current low IPTp coverage represents considerable missed opportunitie...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-440
更新日期:2014-11-20 00:00:00
abstract:BACKGROUND:Early and accurate diagnosis of Plasmodium falciparum infection is important for providing appropriate treatment to patients with malaria. However, technical limitations of currently available diagnostic tests limit their use in control programs. One possible explanation for the vulnerability of current anti...
journal_title:Malaria journal
pub_type: 杂志文章
doi:10.1186/1475-2875-13-277
更新日期:2014-07-18 00:00:00