Keep the quality high: the benefits of lot testing for the quality control of malaria rapid diagnostic tests.

abstract：BACKGROUND:Malaria is a notifiable disease in the Netherlands, a non-endemic country. Imported malaria infections occur regularly among travellers, migrants and visitors. Surveillance data were analysed from 2008 to 2015. Trends in amounts of notifications among risk groups were analysed using Poisson regression. For a...

journal_title：Malaria journal

authors： de Gier B,Suryapranata FS,Croughs M,van Genderen PJ,Keuter M,Visser LG,van Vugt M,Sonder GJ

更新日期：2017-02-02 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDTs) have become the most common diagnostic tool for detection of Plasmodium falciparum malaria, in particular in remote areas. RDT blood spots provide a source of parasite DNA for molecular analysis. In this study, the utility of RDTs for molecular analysis and the performance of di...

journal_title：Malaria journal

authors： Srisutham S,Suwannasin K,Mathema VB,Sriprawat K,Smithuis FM,Nosten F,White NJ,Dondorp AM,Imwong M

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmodium vivax malaria whe...

journal_title：Malaria journal

authors： Njokah MJ,Kang'ethe JN,Kinyua J,Kariuki D,Kimani FT

更新日期：2016-07-22 00:00:00

abstract：BACKGROUND:Five species of Plasmodium are known to infect humans. For proper treatment of malaria, accurate identification of the parasite species is crucial. The current gold standard for malaria diagnosis is microscopic examination of Giemsa-stained blood smears. Since the parasite species are identified by microscop...

journal_title：Malaria journal

authors： Hashimoto M,Sakamoto H,Ido Y,Tanaka M,Yatsushiro S,Kajimoto K,Kataoka M

更新日期：2018-06-19 00:00:00

abstract：BACKGROUND:Rapid diagnostic tests (RDT) and real-time PCR (qPCR) assays are sensitive for diagnosing malaria, but because they detect antigen and DNA, respectively, positivity may not reflect active infection. Performance characteristics of RDT and qPCR in Plasmodium falciparum positive specimens were evaluated over ti...

journal_title：Malaria journal

authors： Phuong M,Lau R,Ralevski F,Boggild AK

更新日期：2015-09-17 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether a selection of South African ethnomedicinal plants included in this study displayed insecticidal properties when screened against adult stages of the mosquito. METHODS:381 crude extracts of 80 plant taxa in 42 families were sprayed onto ceramic tiles and screened...

journal_title：Malaria journal

authors： Maharaj R,Maharaj V,Crouch NR,Bhagwandin N,Folb PI,Pillay P,Gayaram R

更新日期：2011-08-11 00:00:00

abstract：BACKGROUND:With the dramatic increase in international travel among Chinese people, the risk of malaria importation from malaria-endemic regions threatens the achievement of the malaria elimination goal of China. METHODS:Epidemiological investigations of all imported malaria cases were conducted in nine provinces of C...

journal_title：Malaria journal

authors： Li Z,Zhang Q,Zheng C,Zhou S,Sun J,Zhang Z,Geng Q,Zhang H,Wang L,Lai S,Hu W,Clements AC,Zhou XN,Yang W

更新日期：2016-03-05 00:00:00

abstract：:Plasmodium falciparum infections present novel challenges for vaccine development, including parasite replication dynamics not previously encountered for viral pathogens, and enormous diversity in target antigens. These challenges are illustrated by using a mathematical model to describe the association between the pr...

journal_title：Malaria journal

authors： White MT,Smith DL

更新日期：2013-08-08 00:00:00

abstract：:Plasmodium knowlesi is a potentially life-threatening zoonotic malaria parasite due to its relatively short erythrocytic cycle. Microscopic identification of P. knowlesi is difficult, with "compacted parasite cytoplasm" being one of the important identifying keys. This report is about a case of hyperparasitaemic human...

journal_title：Malaria journal

authors： Lee WC,Chin PW,Lau YL,Chin LC,Fong MY,Yap CJ,Supramaniam RR,Mahmud R

更新日期：2013-03-06 00:00:00

abstract：BACKGROUND:Mozambique implemented artemisinin-based combinations therapy (ACT) using artemether-lumefantrine (AL) as the first-line treatment for uncomplicated malaria in 2009. AL remains highly efficacious, but widespread use may soon facilitate emergence of artemisinin tolerance/resistance. The prevalence of pfmdr1 d...

journal_title：Malaria journal

authors： Lobo E,de Sousa B,Rosa S,Figueiredo P,Lobo L,Pateira S,Fernandes N,Nogueira F

更新日期：2014-08-06 00:00:00

abstract：BACKGROUND:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is currently a threat to malaria elimination due to risk of primaquine-induced haemolysis in G6PD deficient individuals. The World Health Organization (WHO) recommends G6PD screening before providing primaquine as a radical treatment against vivax malaria. ...

journal_title：Malaria journal

authors： Marasini B,Lal BK,Thapa S,Awasthi KR,Bajracharya B,Khanal P,Neupane S,Jha SN,Acharya S,Iama S,Koirala M,Koirala D,Bhandari S,Mahato RK,Chaudhary A,Ghimire P,Magar RG,Bhattarai RK,Gornsawun G,Penpitchaporn P,Bancon

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Traditional medicine is readily available in Tanzania, and local terms like degedege is widely used for malaria-like illnesses, often associated with supernatural forces. Malaria prevention and intervention efforts can benefit from policy-makers' awareness of local perceptions and beliefs in the rural areas ...

journal_title：Malaria journal

authors： Spjeldnæs AO,Kitua AY,Blomberg B

更新日期：2014-05-28 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the profile of antibodies against several antigens of Plasmodium vivax and Plasmodium falciparum in Mandalay, Myanmar. METHODS:Malaria parasites were identified by microscopic examination. To test the antibodies against P. vivax and P. falciparum in sera, an indirect...

journal_title：Malaria journal

authors： Kim TS,Kim HH,Kim JY,Kong Y,Na BK,Lin K,Moon SU,Kim YJ,Kwon MH,Sohn Y,Kim H,Lee HW

更新日期：2011-08-06 00:00:00

abstract：BACKGROUND:In rural south-eastern Tanzania, Anopheles funestus is a major malaria vector, and has been implicated in nearly 90% of all infective bites. Unfortunately, little is known about the natural ecological requirements and survival strategies of this mosquito species. METHODS:Potential mosquito aquatic habitats ...

journal_title：Malaria journal

authors： Nambunga IH,Ngowo HS,Mapua SA,Hape EE,Msugupakulya BJ,Msaky DS,Mhumbira NT,Mchwembo KR,Tamayamali GZ,Mlembe SV,Njalambaha RM,Lwetoijera DW,Finda MF,Govella NJ,Matoke-Muhia D,Kaindoa EW,Okumu FO

更新日期：2020-06-23 00:00:00

abstract：BACKGROUND:Insecticide resistance is the major emerging challenge facing the malaria vector control programmes in Tanzania. Proper monitoring and detection is of paramount importance guiding the vector control programmes. This paper presents the effect of mosquito aging on insecticide resistance status in Anopheles ara...

journal_title：Malaria journal

authors： Mbepera S,Nkwengulila G,Peter R,Mausa EA,Mahande AM,Coetzee M,Kweka EJ

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:Monitoring and evaluation of malaria programmes may require a combination of approaches to detect any effects of control. This is particularly true at lower transmission levels where detecting both infection and exposure to infection will provide additional evidence of any change. This paper describes use of...

journal_title：Malaria journal

authors： Stevenson JC,Stresman GH,Baidjoe A,Okoth A,Oriango R,Owaga C,Marube E,Bousema T,Cox J,Drakeley C

更新日期：2015-10-26 00:00:00

abstract：BACKGROUND:Arthropod vectors of disease may encounter more than one infected host during the course of their lifetime. The consequences of super-infection to parasite development are rarely investigated, but may have substantial epidemiological and evolutionary consequences. METHODS:Using a rodent malaria model system...

journal_title：Malaria journal

authors： Ferguson HM,Read AF

更新日期：2004-05-19 00:00:00

abstract：BACKGROUND:Individuals in a malaria endemic community differ from one another. Many of these differences, such as heterogeneities in transmission or treatment-seeking behaviour, affect malaria epidemiology. The different kinds of heterogeneity are likely to be correlated. Little is known about their impact on the shape...

journal_title：Malaria journal

authors： Ross A,Smith T

更新日期：2010-05-17 00:00:00

abstract：BACKGROUND:There has been much debate about the appropriate statistical methodology for the evaluation of malaria field studies and the challenges in interpreting data arising from these trials. METHODS:The present paper describes, for a pivotal phase III efficacy of the RTS, S/AS01 malaria vaccine, the methods of the...

journal_title：Malaria journal

authors： Lievens M,Aponte JJ,Williamson J,Mmbando B,Mohamed A,Bejon P,Leach A

更新日期：2011-08-04 00:00:00

abstract：BACKGROUND:The use of rapid diagnostic tests (RDTs) to diagnose malaria is common in sub-Saharan African laboratories, remote primary health facilities and in the community. Currently, there is a lack of reliable methods to ascertain health worker competency to accurately use RDTs in the testing and diagnosis of malari...

journal_title：Malaria journal

authors： Dorkenoo AM,Kouassi KC,Koura AK,Adams ML,Gbada K,Katawa G,Yakpa K,Charlebois R,Milgotina E,Merkel MO,Aidoo M

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:The Plasmodium falciparum multidrug resistance 1 transporter, PfMDR1, contains five amino acid polymorphisms that are suggested to be involved in altered drug transport from the parasite's cytosol into the digestive vacuole (DV). Transport of a substrate into another intracellular compartment influences drug...

journal_title：Malaria journal

authors： Reiling SJ,Rohrbach P

更新日期：2015-07-15 00:00:00

abstract：BACKGROUND:The current target of universal access to long-lasting, insecticide-treated nets (LLIN) is 80% coverage to reduce malaria deaths by 75% by 2015. So far, campaigns have been the main channel for large-scale delivery of LLINs, however the World Health Organization has recommended that equal priority should be ...

journal_title：Malaria journal

authors： Okell LC,Paintain LS,Webster J,Hanson K,Lines J

更新日期：2012-09-13 00:00:00

abstract：BACKGROUND:Plasmodium vivax preferentially infects Duffy-positive reticulocytes and infections typically have few parasite-infected cells in the peripheral circulation. These features complicate detection and quantification by flow cytometry (FC) using standard nucleic acid-based staining methods. A simple antibody-bas...

journal_title：Malaria journal

authors： Roobsoong W,Maher SP,Rachaphaew N,Barnes SJ,Williamson KC,Sattabongkot J,Adams JH

更新日期：2014-02-14 00:00:00

abstract：BACKGROUND:Fixed-dose combination antimalarial drugs have played an increasingly important role in the treatment and chemoprophylaxis of falciparum malaria since the worldwide failure of monotherapy with chloroquine. Atovaquone-proguanil is one such combination drug used both for prophylaxis in travellers, and for trea...

journal_title：Malaria journal

authors： Sutherland CJ,Laundy M,Price N,Burke M,Fivelman QL,Pasvol G,Klein JL,Chiodini PL

更新日期：2008-11-20 00:00:00

abstract：BACKGROUND:Polyclonal B-cell activation is well known to occur in Plasmodium infections, but its role in pathogenesis or protection remains unclear. However, protective properties of natural antibodies have previously been demonstrated in other contexts. METHODS:Sera from asymptomatic and symptomatic Plasmodium-infect...

journal_title：Malaria journal

authors： Fesel C,Goulart LF,Silva Neto A,Coelho A,Fontes CJ,Braga EM,Vaz NM

更新日期：2005-01-20 00:00:00

abstract：BACKGROUND:Resistance to multiple classes of insecticides has been detected in the malaria vector Anopheles albimanus in northwest Peru. Acetylcholinesterase (AChE) insensitivity has previously been associated with resistance to organophosphate (OP) and carbamate (CA) insecticides in arthropods. A single point mutation...

journal_title：Malaria journal

authors： Liebman KA,Pinto J,Valle J,Palomino M,Vizcaino L,Brogdon W,Lenhart A

更新日期：2015-02-14 00:00:00

abstract：:The global health community is interested in the health impact of the billions of dollars invested to fight malaria in Africa. A recent publication used trends in malaria cases and deaths based on health facility records to evaluate the impact of malaria control efforts in Rwanda and Ethiopia. Although the authors dem...

journal_title：Malaria journal

authors： Rowe AK,Kachur SP,Yoon SS,Lynch M,Slutsker L,Steketee RW

更新日期：2009-09-03 00:00:00

abstract：BACKGROUND:Zooprophylaxis, the diversion of disease carrying insects from humans to animals, may reduce transmission of diseases such as malaria. However, as the number of animals increases, improved availability of blood meals may increase mosquito survival, thereby countering the impact of diverting feeds. METHODS:C...

journal_title：Malaria journal

authors： Saul A

更新日期：2003-09-19 00:00:00

abstract：BACKGROUND:Malaria in highland areas of Kenya affects children and adults. Local clinicians include symptoms other than fever when screening for malaria because they believe that fever alone does not capture all cases of malaria. METHODS:Individuals who presented to dispensaries in a highland Kenya site of low, unstab...

journal_title：Malaria journal

authors： Mutanda AL,Cheruiyot P,Hodges JS,Ayodo G,Odero W,John CC

更新日期：2014-04-30 00:00:00

abstract：BACKGROUND:Tafenoquine is an 8-aminoquinoline being developed for radical cure (blood and liver stage elimination) of Plasmodium vivax. During monotherapy treatment, the compound exhibits slow parasite and fever clearance times, and toxicity in glucose-6-phosphate dehydrogenase (G6PD) deficiency is a concern. Combinati...

journal_title：Malaria journal

authors： Dow GS,Gettayacamin M,Hansukjariya P,Imerbsin R,Komcharoen S,Sattabongkot J,Kyle D,Milhous W,Cozens S,Kenworthy D,Miller A,Veazey J,Ohrt C

更新日期：2011-07-29 00:00:00