当前位置： SCI文献检索 > MALARIA JOURNAL期刊下所有文献 > Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group.

Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group.

Abstract：

:The goal to eliminate malaria from the Asia-Pacific by 2030 will require the safe and widespread delivery of effective radical cure of malaria. In October 2017, the Asia Pacific Malaria Elimination Network Vivax Working Group met to discuss the impediments to primaquine (PQ) radical cure, how these can be overcome and the methodological difficulties in assessing clinical effectiveness of radical cure. The salient discussions of this meeting which involved 110 representatives from 18 partner countries and 21 institutional partner organizations are reported. Context specific strategies to improve adherence are needed to increase understanding and awareness of PQ within affected communities; these must include education and health promotion programs. Lessons learned from other disease programs highlight that a package of approaches has the greatest potential to change patient and prescriber habits, however optimizing the components of this approach and quantifying their effectiveness is challenging. In a trial setting, the reactivity of participants results in patients altering their behaviour and creates inherent bias. Although bias can be reduced by integrating data collection into the routine health care and surveillance systems, this comes at a cost of decreasing the detection of clinical outcomes. Measuring adherence and the factors that relate to it, also requires an in-depth understanding of the context and the underlying sociocultural logic that supports it. Reaching the elimination goal will require innovative approaches to improve radical cure for vivax malaria, as well as the methods to evaluate its effectiveness.

journal_name

Malar J

journal_title

Malaria journal

authors

Thriemer K,Bobogare A,Ley B,Gudo CS,Alam MS,Anstey NM,Ashley E,Baird JK,Gryseels C,Jambert E,Lacerda M,Laihad F,Marfurt J,Pasaribu AP,Poespoprodjo JR,Sutanto I,Taylor WR,van den Boogaard C,Battle KE,Dysoley L,Ghim

doi

10.1186/s12936-018-2380-8

subject

Has Abstract

pub_date

2018-06-20 00:00:00

pages

241

issue

1

issn

1475-2875

pii

10.1186/s12936-018-2380-8

journal_volume

17

pub_type

相关文献

MALARIA JOURNAL文献大全
  • Detection of a substantial number of sub-microscopic Plasmodium falciparum infections by polymerase chain reaction: a potential threat to malaria control and diagnosis in Ethiopia.

    abstract：BACKGROUND:Prompt and effective malaria diagnosis not only alleviates individual suffering, but also decreases malaria transmission at the community level. The commonly used diagnostic methods, microscopy and rapid diagnostic tests, are usually insensitive at very low-density parasitaemia. Molecular techniques, on the ...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-12-352

    authors： Golassa L,Enweji N,Erko B,Aseffa A,Swedberg G

    更新日期：2013-10-03 00:00:00

  • Expanding malaria diagnosis and treatment in Lao PDR: lessons learned from a public-private mix initiative.

    abstract：BACKGROUND:As in other countries of the Greater Mekong Sub-region (GMS), the private health sector constitutes a significant avenue where malaria services are provided and presents a unique opportunity for public-private collaboration. In September 2008, a public-private mix (PPM) strategy was launched initially in fou...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-017-2104-5

    authors： Simmalavong N,Phommixay S,Kongmanivong P,Sichanthongthip O,Hongvangthong B,Gopinath D,Sintasath DM

    更新日期：2017-11-13 00:00:00

  • The impact of behaviour change communication on the use of insecticide treated nets: a secondary analysis of ten post-campaign surveys from Nigeria.

    abstract：BACKGROUND:Mass distribution campaigns of insecticide-treated nets for malaria prevention are usually accompanied by intensive behaviour change communication (BCC) to encourage hanging and use of nets. However, data on the effectiveness of these communication efforts are scarce. In preparation for the next round of mas...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-016-1463-7

    authors： Kilian A,Lawford H,Ujuju CN,Abeku TA,Nwokolo E,Okoh F,Baba E

    更新日期：2016-08-19 00:00:00

  • Malaria risk factor assessment using active and passive surveillance data from Aceh Besar, Indonesia, a low endemic, malaria elimination setting with Plasmodium knowlesi, Plasmodium vivax, and Plasmodium falciparum.

    abstract：BACKGROUND:As malaria transmission declines, it becomes more geographically focused and more likely due to asymptomatic and non-falciparum infections. To inform malaria elimination planning in the context of this changing epidemiology, local assessments on the risk factors for malaria infection are necessary, yet chall...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-016-1523-z

    authors： Herdiana H,Cotter C,Coutrier FN,Zarlinda I,Zelman BW,Tirta YK,Greenhouse B,Gosling RD,Baker P,Whittaker M,Hsiang MS

    更新日期：2016-09-13 00:00:00

  • Plasmodium vivax severe imported malaria in two migrants in France.

    abstract：BACKGROUND:With less than one severe case per year in average, Plasmodium vivax is very rarely associated with severe imported malaria in France. Two cases of P. vivax severe malaria occurred in patients with no evident co-morbidity. Interestingly, both cases did not occur at the primary infection but during relapses. ...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-019-3067-5

    authors： Izri A,Cojean S,Leblanc C,Cohen Y,Bouchaud O,Durand R

    更新日期：2019-12-16 00:00:00

  • Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers immunized with a Plasmodium falciparum adenovirus-vectored

    abstract：BACKGROUND:Malaria is responsible for up to a 600,000 deaths per year; conveying an urgent need for the development of a malaria vaccine. Studies with whole sporozoite vaccines in mice and non-human primates have shown that sporozoite-induced CD8+ T cells targeting liver stage antigens can mediate sterile protection. T...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-12-376

    authors： Schwenk R,Banania G,Epstein J,Kim Y,Peters B,Belmonte M,Ganeshan H,Huang J,Reyes S,Stryhn A,Ockenhouse CF,Buus S,Richie TL,Sedegah M

    更新日期：2013-10-29 00:00:00

  • Electrocardiographic study in Ghanaian children with uncomplicated malaria, treated with artesunate-amodiaquine or artemether-lumefantrine.

    abstract：BACKGROUND:Several anti-malarial drugs are associated with adverse cardiovascular effects. These effects may be exacerbated when different anti-malarials are used in combination. There has been no report yet on the potential cardiac effects of the combination artesunate-amodiaquine. METHODS:Electrocardiographic (ECG) ...

    journal_title：Malaria journal

    pub_type： 临床试验,杂志文章

    doi：10.1186/1475-2875-11-420

    authors： Adjei GO,Oduro-Boatey C,Rodrigues OP,Hoegberg LC,Alifrangis M,Kurtzhals JA,Goka BQ

    更新日期：2012-12-17 00:00:00

  • Prevalence of Plasmodium parasites in non-human primates and mosquitoes in areas with different degrees of fragmentation in Colombia.

    abstract：BACKGROUND:Parasites from the genus Plasmodium, the aetiological agent of malaria in humans, can also infect non-human primates (NHP), increasing the potential risk of zoonotic transmission with its associated global public health concerns. In Colombia, there are no recent studies on Plasmodium spp. infecting free-rang...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-019-2910-z

    authors： Rondón S,León C,Link A,González C

    更新日期：2019-08-19 00:00:00

  • Genetic polymorphism and natural selection of circumsporozoite surface protein in Plasmodium falciparum field isolates from Myanmar.

    abstract：BACKGROUND:Plasmodium falciparum circumsporozoite protein (PfCSP) is one of the most extensively studied malaria vaccine candidates, but the genetic polymorphism of PfCSP within and among the global P. falciparum population raises concerns regarding the efficacy of a PfCSP-based vaccine efficacy. In this study, genetic...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-018-2513-0

    authors： Lê HG,Kang JM,Moe M,Jun H,Thái TL,Lee J,Myint MK,Lin K,Sohn WM,Shin HJ,Kim TS,Na BK

    更新日期：2018-10-12 00:00:00

  • Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon.

    abstract：BACKGROUND:Transmission of malaria from man to mosquito depends on the presence of gametocytes, the sexual stage of Plasmodium parasites in the infected host. Naturally acquired antibodies against gametocytes exist and may play a role in controlling transmission by limiting the gametocyte development in the circulation...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-017-1827-7

    authors： Gebru T,Ajua A,Theisen M,Esen M,Ngoa UA,Issifou S,Adegnika AA,Kremsner PG,Mordmüller B,Held J

    更新日期：2017-04-26 00:00:00

  • The counterfeit anti-malarial is a crime against humanity: a systematic review of the scientific evidence.

    abstract：BACKGROUND:The counterfeiting of anti-malarials represents a form of attack on global public health in which fake and substandard anti-malarials serve as de facto weapons of mass destruction, particularly in resource-constrained endemic settings, where malaria causes nearly 660,000 preventable deaths and threatens mill...

    journal_title：Malaria journal

    pub_type： 杂志文章,评审

    doi：10.1186/1475-2875-13-209

    authors： Karunamoorthi K

    更新日期：2014-06-02 00:00:00

  • Therapeutic efficacy of artemether-lumefantrine in uncomplicated falciparum malaria in India.

    abstract：BACKGROUND:Artemisinin-based combination therapy (ACT) is the treatment of choice for uncomplicated falciparum malaria. Artemether-lumefantrine (AL), a fixed dose co-formulation, has recently been approved for marketing in India, although it is not included in the National Drug Policy for treatment of malaria. Efficacy...

    journal_title：Malaria journal

    pub_type： 临床试验,杂志文章

    doi：10.1186/1475-2875-8-107

    authors： Valecha N,Srivastava P,Mohanty SS,Mittra P,Sharma SK,Tyagi PK,Pradhan K,Dev V,Singh R,Dash AP,Sharma YD

    更新日期：2009-05-19 00:00:00

  • Polymorphism patterns in Duffy-binding protein among Thai Plasmodium vivax isolates.

    abstract：BACKGROUND:The Duffy-binding protein II of Plasmodium vivax (PvDBPII) has been considered as an attractive target for vaccine-mediated immunity despite a possible highly polymorphic nature. Among seven PvDBP domains, domain II has been shown to exhibit a high rate of nonsynonymous polymorphism, which has been suggested...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-7-112

    authors： Gosi P,Khusmith S,Khalambaheti T,Lanar DE,Schaecher KE,Fukuda MM,Miller SR

    更新日期：2008-06-26 00:00:00

  • Post-malaria neurological syndrome: four cases, review of the literature and clarification of the nosological framework.

    abstract：BACKGROUND:Post-malaria neurological syndrome (PMNS) is a debated entity, defined by neurological complications following a post-malaria symptom-free period and a negative blood smear. Four cases of PMNS are hereby reported and a review the literature performed to clarify the nosological framework of this syndrome. ME...

    journal_title：Malaria journal

    pub_type： 杂志文章,评审

    doi：10.1186/s12936-018-2542-8

    authors： Tamzali Y,Demeret S,Haddad E,Guillot H,Caumes E,Jauréguiberry S

    更新日期：2018-10-26 00:00:00

  • Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro.

    abstract：BACKGROUND:Cerebral malaria (CM) is associated with morbidity and mortality despite the use of potent anti-malarial agents. Brain endothelial cell activation and dysfunction from oxidative and inflammatory host responses and products released by Plasmodium falciparum-infected erythrocytes (IE), are likely the major con...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-020-03447-7

    authors： Mita-Mendoza NK,Magallon-Tejada A,Parmar P,Furtado R,Aldrich M,Saidi A,Taylor T,Smith J,Seydel K,Daily JP

    更新日期：2020-10-21 00:00:00

  • Conceptual framework and rationale.

    abstract：:The sterile insect technique (SIT) has been shown to be an effective and sustainable genetic approach to control populations of selected major pest insects, when part of area-wide integrated pest management (AW-IPM) programmes. The technique introduces genetic sterility in females of the target population in the field...

    journal_title：Malaria journal

    pub_type： 杂志文章,评审

    doi：10.1186/1475-2875-8-S2-S1

    authors： Robinson AS,Knols BG,Voigt G,Hendrichs J

    更新日期：2009-11-16 00:00:00

  • Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP).

    abstract：BACKGROUND:Plasmodium falciparum circumsporozoite protein (CSP) is a leading malaria vaccine candidate antigen, known to elicit protective antibody responses in humans (RTS,S vaccine). Recently, a DNA prime / adenovirus (Ad) vector boost vaccine encoding CSP and a second P. falciparum antigen, apical membrane antigen-1...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-12-185

    authors： Sedegah M,Kim Y,Ganeshan H,Huang J,Belmonte M,Abot E,Banania JG,Farooq F,McGrath S,Peters B,Sette A,Soisson L,Diggs C,Doolan DL,Tamminga C,Villasante E,Hollingdale MR,Richie TL

    更新日期：2013-06-05 00:00:00

  • Mass testing and treatment for malaria in low transmission areas in Amhara Region, Ethiopia.

    abstract：BACKGROUND:In areas with ongoing malaria transmission, strategies to clear parasites from populations can reduce infection and transmission. The objective of this paper was to describe a malaria mass testing and treatment (MTAT) intervention implemented in six kebeles (villages) in Amhara Region, Ethiopia, at the begin...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-016-1333-3

    authors： Scott CA,Yeshiwondim AK,Serda B,Guinovart C,Tesfay BH,Agmas A,Zeleke MT,Guesses GS,Ayenew AL,Workie WM,Steketee RW,Earle D,Bezabih B,Getachew A

    更新日期：2016-06-02 00:00:00

  • Epidemiologic features of overseas imported malaria in the People's Republic of China.

    abstract：BACKGROUND:With the dramatic increase in international travel among Chinese people, the risk of malaria importation from malaria-endemic regions threatens the achievement of the malaria elimination goal of China. METHODS:Epidemiological investigations of all imported malaria cases were conducted in nine provinces of C...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-016-1188-7

    authors： Li Z,Zhang Q,Zheng C,Zhou S,Sun J,Zhang Z,Geng Q,Zhang H,Wang L,Lai S,Hu W,Clements AC,Zhou XN,Yang W

    更新日期：2016-03-05 00:00:00

  • Extremely low Plasmodium prevalence in wild plovers and coursers from Cape Verde and Madagascar.

    abstract：BACKGROUND:Relatively little is known about the prevalence of blood parasites in shorebirds, especially those breeding in the tropics. The prevalence of blood parasites of the genera Plasmodium, Haemoproteus and Leucocytozoon was assessed in blood samples from Kentish plovers and cream-coloured coursers in Cape Verde, ...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-017-1892-y

    authors： Martínez-de la Puente J,Eberhart-Phillips LJ,Cristina Carmona-Isunza M,Zefania S,Navarro MJ,Kruger O,Hoffman JI,Székely T,Figuerola J

    更新日期：2017-06-08 00:00:00

  • Rapid identification of chloroquine and atovaquone drug resistance in Plasmodium falciparum using high-resolution melt polymerase chain reaction.

    abstract：BACKGROUND:Drug resistance determination for Plasmodium falciparum infections are important to determining the type of treatment to be given. Besides in vivo experiments, molecular methods, such as sequencing and PCR, are now increasingly being used. Here a cheaper alternative to sequencing or the use of multiplex 5'nu...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-9-134

    authors： Gan LS,Loh JP

    更新日期：2010-05-21 00:00:00

  • Evaluation of the behaviour change communication and community mobilization activities in Myanmar artemisinin resistance containment zones.

    abstract：BACKGROUND:Behaviour change communication (BCC) can improve malaria prevention and treatment behaviour. As a one of the activities under Myanmar Artemisinin Resistance Containment (MARC) programme, BCC have been conducting. This study aimed to evaluate the effectiveness of the behaviour change communication and communi...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-015-1047-y

    authors： Nyunt MH,Aye KM,Kyaw MP,Wai KT,Oo T,Than A,Oo HW,Phway HP,Han SS,Htun T,San KK

    更新日期：2015-12-23 00:00:00

  • Frequent blood feeding enables insecticide-treated nets to reduce transmission by mosquitoes that bite predominately outdoors.

    abstract：BACKGROUND:The effectiveness of vector control on malaria transmission by long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) depends on the vectors entering houses to blood feed and rest when people are inside houses. In the Solomon Islands, significant reductions in malaria have been achieved in...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-016-1195-8

    authors： Russell TL,Beebe NW,Bugoro H,Apairamo A,Chow WK,Cooper RD,Collins FH,Lobo NF,Burkot TR

    更新日期：2016-03-10 00:00:00

  • Decreased motivation in the use of insecticide-treated nets in a malaria endemic area in Burkina Faso.

    abstract：BACKGROUND:The use of insecticide-treated nets (ITN) is an important tool in the Roll Back Malaria (RBM) strategy. For ITNs to be effective they need to be used correctly. Previous studies have shown that many factors, such as wealth, access to health care, education, ethnicity and gender, determine the ownership and u...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-8-175

    authors： Toé LP,Skovmand O,Dabiré KR,Diabaté A,Diallo Y,Guiguemdé TR,Doannio JM,Akogbeto M,Baldet T,Gruénais ME

    更新日期：2009-07-29 00:00:00

  • Prevalence of Plasmodium falciparum field isolates with deletions in histidine-rich protein 2 and 3 genes in context with sub-Saharan Africa and India: a systematic review and meta-analysis.

    abstract：BACKGROUND:In 2017, nearly 80% of malaria morbidity and mortality occurred in sub-Saharan African (SSA) countries and India. Rapid diagnostic tests (RDTs), especially those targeting histidine-rich protein 2 (PfHRP2) of Plasmodium falciparum, have become an important diagnostic tool in these malaria-endemic areas. Howe...

    journal_title：Malaria journal

    pub_type： 杂志文章,meta分析

    doi：10.1186/s12936-019-3090-6

    authors： Kojom LP,Singh V

    更新日期：2020-01-28 00:00:00

  • Analysis of polymorphisms in Plasmodium falciparum genes related to drug resistance: a survey over four decades under different treatment policies in Brazil.

    abstract：BACKGROUND:Anti-malarial resistance in Plasmodium falciparum remains an obstacle for malaria control. Resistance-associated genes were analysed in Brazilian samples over four decades to evaluate the impact of different treatment regimens on the parasite genetic profile. METHODS:Samples were collected on filter paper f...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-13-372

    authors： Inoue J,Lopes D,do Rosário V,Machado M,Hristov AD,Lima GF,Costa-Nascimento MJ,Segurado AC,Di Santi SM

    更新日期：2014-09-19 00:00:00

  • Characterization of Plasmodium falciparum and Plasmodium vivax recent exposure in an area of significantly decreased transmission intensity in Central Vietnam.

    abstract：BACKGROUND:In Vietnam, malaria transmission has been reduced to very low levels over the past 20 years, and as a consequence, the country aims to eliminate malaria by 2030. This study aimed to characterize the dynamics and extent of the parasite reservoir in Central Vietnam, in order to further target elimination strat...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-018-2326-1

    authors： Kattenberg JH,Erhart A,Truong MH,Rovira-Vallbona E,Vu KAD,Nguyen THN,Nguyen VH,Nguyen VV,Bannister-Tyrrell M,Theisen M,Bennet A,Lover AA,Tran TD,Nguyen XX,Rosanas-Urgell A

    更新日期：2018-04-27 00:00:00

  • Comparison of an assumed versus measured leucocyte count in parasite density calculations in Papua New Guinean children with uncomplicated malaria.

    abstract：BACKGROUND:The accuracy of the World Health Organization method of estimating malaria parasite density from thick blood smears by assuming a white blood cell (WBC) count of 8,000/μL has been questioned in several studies. Since epidemiological investigations, anti-malarial efficacy trials and routine laboratory reporti...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-13-145

    authors： Laman M,Moore BR,Benjamin J,Padapu N,Tarongka N,Siba P,Betuela I,Mueller I,Robinson LJ,Davis TM

    更新日期：2014-04-16 00:00:00

  • Evaluating a 24-h mobile reporting system for malaria notifications in comparison with a paper-based system in South Africa, 2015.

    abstract：BACKGROUND:As South Africa strives to achieve malaria elimination by 2018 (zero local cases) the country needs to strengthen its disease surveillance system by reducing the timeliness from case diagnosis to notification of key stakeholders in the malaria programme. This study evaluated the feasibility of a 24-h mobile ...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/s12936-018-2451-x

    authors： Baloyi RE,Shandukani MB,Graffy R,Misiani E,Mayet N,Mabunda E,Mabuza A,Qwabe B,Ngwenyama B,Reddy C,Moonasar D

    更新日期：2018-08-23 00:00:00

  • Exploiting the behaviour of wild malaria vectors to achieve high infection with fungal biocontrol agents.

    abstract：BACKGROUND:Control of mosquitoes that transmit malaria has been the mainstay in the fight against the disease, but alternative methods are required in view of emerging insecticide resistance. Entomopathogenic fungi are candidate alternatives, but to date, few trials have translated the use of these agents to field-base...

    journal_title：Malaria journal

    pub_type： 杂志文章

    doi：10.1186/1475-2875-11-87

    authors： Mnyone LL,Lyimo IN,Lwetoijera DW,Mpingwa MW,Nchimbi N,Hancock PA,Russell TL,Kirby MJ,Takken W,Koenraadt CJ

    更新日期：2012-03-26 00:00:00