Histone-H1 inhibits translation by reticulocyte lysates with relative mRNA selectivity.

abstract：:The exons of the lecithin:cholesterol acyltransferase (LCAT) gene in DNA samples from two of the original Swedish Fish Eye Disease patients have been amplified by polymerase chain reactions and sequenced by the dideoxy method. The two patients apparently were unrelated. In both patients a mutation in codon 10 of the f...

journal_title：Biochemical and biophysical research communications

authors： Skretting G,Prydz H

更新日期：1992-01-31 00:00:00

abstract：:O-GlcNAcylation is a dynamic and reversible post-translational modification of cytonuclear molecules that regulates cellular signaling. Elevated O-GlcNAcylation is a general property of cancer and plays a critical role in cancer progression. We previously showed that the expression of FOXM1, a critical oncogenic trans...

journal_title：Biochemical and biophysical research communications

authors： Ueda Y,Moriwaki K,Takeuchi T,Higuchi K,Asahi M

更新日期：2020-01-15 00:00:00

abstract：:Disturbances of serotonergic pathways have been implicated in a wide variety of neuropsychiatric disorders such as depression, anxiety, migraine, and substance abuse. Genetic variation in genes coding for serotonin receptor proteins might well be involved in the genetic predisposition to these diseases and/or of pharm...

journal_title：Biochemical and biophysical research communications

authors： Nöthen MM,Erdmann J,Shimron-Abarbanell D,Propping P

更新日期：1994-12-15 00:00:00

abstract：:We provide the first demonstration for a Na+/Ca2+ exchanger, NCX-1, in the osteoclast. We speculate that by using Na+ exchange, NCX-1 couples H+ extrusion with Ca2+ fluxes during bone resorption. Microspectrofluorimetry of fura-2-loaded osteoclasts revealed a rapid and sustained, but reversible, cytosolic Ca2+ elevati...

journal_title：Biochemical and biophysical research communications

authors： Moonga BS,Davidson R,Sun L,Adebanjo OA,Moser J,Abedin M,Zaidi N,Huang CL,Zaidi M

更新日期：2001-05-18 00:00:00

abstract：:DNA mismatch repair (MMR) is critical for the maintenance of genomic stability. MMR is initiated by recognition of DNA mismatches by the protein, MutS, which subsequently recruits downstream repair factors. To better understand the mechanism by which MutS identifies and specifically binds mismatched basepairs embedded...

journal_title：Biochemical and biophysical research communications

authors： Jia Y,Bi L,Li F,Chen Y,Zhang C,Zhang X

更新日期：2008-08-08 00:00:00

abstract：:Atrial fibrillation (AF) is the most common cardiac arrhythmia in the clinic, and accounts for more than 15% of strokes. Mutations in cardiac sodium channel alpha, beta1 and beta2 subunit genes (SCN5A, SCN1B, and SCN2B) have been identified in AF patients. We hypothesize that mutations in the sodium channel beta3 subu...

journal_title：Biochemical and biophysical research communications

authors： Wang P,Yang Q,Wu X,Yang Y,Shi L,Wang C,Wu G,Xia Y,Yang B,Zhang R,Xu C,Cheng X,Li S,Zhao Y,Fu F,Liao Y,Fang F,Chen Q,Tu X,Wang QK

更新日期：2010-07-16 00:00:00

abstract：:The results presented here show that a decrease in the concentration of total polyamines, due to a decrease in putrescine and spermine, occurs during oogenesis in Xenopus laevis. The microinjection of spermine or spermidine decreases the hormonal responsiveness (maturation) of the fully-grown oocytes. This effect is s...

journal_title：Biochemical and biophysical research communications

authors： Osborne HB,Mulner-Lorillon O,Marot J,Belle R

更新日期：1989-01-31 00:00:00

abstract：:Multidrug resistance protein 2 (Mrp2) is considered the major mammalian membrane transporter of non-bile salt organic anions from liver to bile. Using Mrp2-deficient rats, we show that the protein is not essential for biliary excretion of biliverdin, its IIIalpha and XIIIalpha isomers, mesobiliverdin XIIIalpha or bili...

journal_title：Biochemical and biophysical research communications

authors： McDonagh AF,Lightner DA,Kar AK,Norona WS

更新日期：2002-05-10 00:00:00

abstract：:Cancer-induced pain (CIP) is a kind of chronic pain that occurs during cancer progression over time. However, the mechanisms are largely unknown, and clinical treatment remains challenging. LncRNAs have been reported to play critical roles in various biological processes, including chronic pain. The aim of our study w...

journal_title：Biochemical and biophysical research communications

authors： Sun RM,Wei J,Wang SS,Xu GY,Jiang GQ

更新日期：2020-04-16 00:00:00

abstract：:The cobalt(II) derivative of cucumber basic blue copper protein "plantacyanin" has been prepared. The visible absorption, circular dichroic and magnetic circular dichroic spectra of Co(II)-plantacyanin are similar to those of Co(II)-plastocyanin, indicating that the stereochemistry of Co(II) is tetrahedral and at leas...

journal_title：Biochemical and biophysical research communications

authors： Sakurai T

更新日期：1986-09-30 00:00:00

abstract：:Septins, a conserved family of GTPases, are heteropolymeric filament-forming proteins that associate with the cell membrane and cytoskeleton and serve essential functions in cell division and morphogenesis. Their roles in fungal cell wall chitin deposition, septation, cytokinesis, and sporulation have been well establ...

journal_title：Biochemical and biophysical research communications

authors： Juvvadi PR,Fortwendel JR,Rogg LE,Steinbach WJ

更新日期：2011-02-11 00:00:00

abstract：:Lanosterol synthase [(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol forming), EC 5.4.99.7] catalyzes the cyclization of (S)-2,3-oxidosqualene to lanosterol in the reaction that forms the sterol nucleus. We report herein the cloning and characterization of the human gene (OSC) encoding lanosterol synthase, a predi...

journal_title：Biochemical and biophysical research communications

authors： Baker CH,Matsuda SP,Liu DR,Corey EJ

更新日期：1995-08-04 00:00:00

abstract：:Uracil-DNA glycosylase (UNG) is the primary enzyme responsible for removing uracil residues from DNA. Increasing evidence suggests that UNG may be a potential target for the development of novel antiviral and/or anticancer agents. To determine whether the uracil-DNA glycosylase inhibitor protein (UGI) could be used to...

journal_title：Biochemical and biophysical research communications

authors： Studebaker AW,Ariza ME,Williams MV

更新日期：2005-08-26 00:00:00

abstract：:Efonidipine is a dual L-/T- type calcium channel blocker with a slow onset of action and a long lasting effect that exibihits antihypertensive and nephroprotective effects. differs from most other DHPs which can induce reflex tachycardia. Efonidipine reduces blood pressure without decreasing cardiac output and exerts ...

journal_title：Biochemical and biophysical research communications

authors： Xu F,Xiong W,Huang Y,Shen J,Zhou D,Tang L

更新日期：2019-06-04 00:00:00

abstract：:Phosphoglucose isomerase (PGI) is a well-characterized ubiquitous enzyme involved in the glycolytic pathway. It catalyzes the reversible isomerization of D-glucopyranose-6-phosphate and D-fructofuranose-6-phosphate and is present in all living cells. However, there is interspecies variation at the level of the primary...

journal_title：Biochemical and biophysical research communications

authors： Mathur D,Ahsan Z,Tiwari M,Garg LC

更新日期：2005-11-18 00:00:00

abstract：:Previous studies have shown that a specific inhibitor of insulin-like growth factor (IGF) action in vitro can be isolated from normal human serum and subsequently partially purified on an IGF-affinity column. The ability of the inhibitor to bind the IGFs has now been confirmed directly using covalent cross-linking tec...

journal_title：Biochemical and biophysical research communications

authors： Ooi GT,Herington AC

更新日期：1986-05-29 00:00:00

abstract：:Palmar fibromatosis is a benign fibroproliferative tumor of unknown etiology, with a high rate of recurrence after excision. The offending cells of palmar fibromatosis are myofibroblasts and the cellular origin of other myofibroblasts has previously been reported to be the bone marrow. However, further clarification o...

journal_title：Biochemical and biophysical research communications

authors： Wang JP,Hui YJ,Wang ST,Huang YC,Chiang ER,Liu CL,Chen TH,Hung SC

更新日期：2011-05-06 00:00:00

abstract：:The delta subunit of the epithelial sodium channel (δENaC) is a member of the ENaC/degenerin family of ion channels. δENaC is distinct from the related α-, β- and γENaC subunits, known for their role in sodium homeostasis and blood pressure control, as δENaC is expressed in brain neurons and activated by external prot...

journal_title：Biochemical and biophysical research communications

authors： Chang T,Ke Y,Ly K,McDonald FJ

更新日期：2011-08-05 00:00:00

abstract：:The current utility of bioluminescence imaging is constrained by a low photon yield that limits temporal sensitivity. Here, we describe an imaging method that uses a chemiluminescent/fluorescent protein, ffLuc-cp156, which consists of a yellow variant of Aequorea GFP and firefly luciferase. We report an improvement in...

journal_title：Biochemical and biophysical research communications

authors： Hara-Miyauchi C,Tsuji O,Hanyu A,Okada S,Yasuda A,Fukano T,Akazawa C,Nakamura M,Imamura T,Matsuzaki Y,Okano HJ,Miyawaki A,Okano H

更新日期：2012-03-09 00:00:00

abstract：:The human MEP1A gene encodes the meprin alpha subunit that consists of a protease domain conserved in the astacin family of metalloendopeptidases and several C-terminal interaction domains present in other proteins. Using the alpha subunit cDNA, we identified two clones from a human P1-derived artificial chromosome (P...

journal_title：Biochemical and biophysical research communications

authors： Jiang W,Beatty BG

更新日期：1999-07-22 00:00:00

abstract：:Since otoacoustic emissions were discovered, the old idea of a second (active) filter in the cochlea has been pursued with considerable dedication. In this contribution a concept explaining the action of the second filter is presented, which is derived from high-frequency resonance: The outer hair cells are excited wh...

journal_title：Biochemical and biophysical research communications

authors： Fritze W

更新日期：1996-06-14 00:00:00

abstract：:Zinc ribbon domain-containing 1 (ZNRD1), a transcription-associated gene, was recently found to be downregulated in human gastric cancer tissues as compared to the matched adjacent nonneoplastic tissues. In this study, we constructed the siRNA eukaryotic expression vectors of ZNRD1 and transfected them into normal gas...

journal_title：Biochemical and biophysical research communications

authors： Hong L,Zhang Y,Liu N,Liu C,Zhi M,Pan Y,Lan M,Sun L,Fan D

更新日期：2004-08-27 00:00:00

abstract：:Colorectal cancer is a common cancer with metachronous distant metastases still threatening overall survival. Tumor oxygen level influences tumor radiosensitivity in relation to autophagy and apoptosis. The objective of this study is to evaluate the expression and interaction between multiple key regulators in differe...

journal_title：Biochemical and biophysical research communications

authors： Tam SY,Wu VWC,Law HKW

更新日期：2019-09-17 00:00:00

abstract：:Prostate cancer (CaP) bone metastasis is an early event that remains inactive until later-stage progression. Reduced levels of circulating androgens, due to andropause or androgen deprivation therapies, alter androgen receptor (AR) coactivator expression. Coactivators shift the balance towards enhanced AR-mediated gen...

journal_title：Biochemical and biophysical research communications

authors： Villagran MA,Gutierrez-Castro FA,Pantoja DF,Alarcon JC,Fariña MA,Amigo RF,Muñoz-Godoy NA,Pinilla MG,Peña EA,Gonzalez-Chavarria I,Toledo JR,Rivas CI,Vera JC,McNerney EM,Onate SA

更新日期：2015-11-27 00:00:00

abstract：:A subclone termed as HSG-S8 was previously isolated from human salivary adenocarcinoma cell line, HSG, and proliferated in a serum-free culture. When HSG-S8 and parental HSG cells were transplanted into nude mice i.m. or s.c., both cells reproducibly induced adenocarcinoma. Furthermore, injection of HSG-S8 consistentl...

journal_title：Biochemical and biophysical research communications

authors： Hatakeyama S,Ohara-Nemoto Y,Kyakumoto S,Satoh M

更新日期：1993-02-15 00:00:00

abstract：:Ubiquitin carboxyl-terminal hydrolases (UCHs) are implicated in the proteolytic processing of polymeric ubiquitin. We have isolated a novel mouse gene for ubiquitin carboxyl-terminal hydrolase isozyme L4. The gene named Uchl4 encodes a novel member of the family of ubiquitin carboxyl-terminal hydrolases (UCHs) whose p...

journal_title：Biochemical and biophysical research communications

authors： Osawa Y,Wang YL,Osaka H,Aoki S,Wada K

更新日期：2001-05-11 00:00:00

abstract：:We have developed a multi-target cell tracking program TADOR, which we applied to a series of fluorescence images. TADOR is based on an active contour model that is modified in order to be free of the problem of locally optimal solutions, and thus is resistant to signal fluctuation and morphological changes. Due to ad...

journal_title：Biochemical and biophysical research communications

authors： Kurokawa H,Noda H,Sugiyama M,Sakaue-Sawano A,Fukami K,Miyawaki A

更新日期：2012-01-20 00:00:00

abstract：:The objective was to investigate whether a graphene coating could improve the surface bioactivity of a cobalt-chromium-molybdenum-based alloy (CoCrMo). Graphene was produced by chemical vapor deposition and transferred to the surface of the CoCrMo alloy using an improved wet transfer approach. The morphology of the sa...

journal_title：Biochemical and biophysical research communications

authors： Zhang Q,Li K,Yan J,Wang Z,Wu Q,Bi L,Yang M,Han Y

更新日期：2018-03-18 00:00:00

abstract：:We report the identification of the full-length cDNA for a novel ATP-binding cassette (ABC) transporter from human macrophages. The mRNA is of 6.8 kb size and contains an open reading frame encoding a polypeptide of 2146 amino acids with a calculated molecular weight of 220 kDa. The predicted protein product is compos...

journal_title：Biochemical and biophysical research communications

authors： Kaminski WE,Orsó E,Diederich W,Klucken J,Drobnik W,Schmitz G

更新日期：2000-07-05 00:00:00

abstract：:The (1)H NMR spectrum of the perchloric acid extract of carp seminal plasma was heavily congested. It is demonstrated that proton-detected C,H chemical shift correlation spectroscopy (HSQC, HSQC-TOCSY) allows an unequivocal identification of proline, glutamate, taurine, and methionine sulfoxide, although several key p...

journal_title：Biochemical and biophysical research communications

authors： Kalic M,Lauterwein J,Büsselmann G,Kamp G

更新日期：2000-03-05 00:00:00