Plasma free metanephrines are superior to urine and plasma catecholamines and urine catecholamine metabolites for the investigation of phaeochromocytoma.

abstract：:A total of 52 of 238 patients (22%) with non-Hodgkin's lymphoma presented with disease in a primary extranodal site. The gastrointestinal tract was the commonest site involved (50%) and diffuse large cell was the commonest histological sub-type of the lymphoma (64%). Survivorship analysis of these patients, treated pr...

journal_title：Pathology

authors： Manoharan A,Smart RC,Pitney WR

更新日期：1986-10-01 00:00:00

abstract：INTRODUCTION:Detection of the V600E hotspot mutation in BRAF oncogene is extremely useful for the screening of hereditary non-polyposis colorectal cancer (Lynch's syndrome) and for the prediction of sensitivity to MEK inhibitors. Here we describe a method for detecting this mutation based upon pyrosequencing technology...

journal_title：Pathology

authors： Tan YH,Liu Y,Eu KW,Ang PW,Li WQ,Salto-Tellez M,Iacopetta B,Soong R

更新日期：2008-04-01 00:00:00

abstract：:Post-transplant lymphoproliferative disorders (PTLD) are a consequence of the immunosuppressive therapy following organ transplant. We describe a patient who developed PTLD seven years after liver transplant and while receiving cyclosporine and prednisone. Magnetic resonance imaging demonstrated a paraspinal mass exte...

journal_title：Pathology

authors： Grosso LE,Bee CS

更新日期：1998-11-01 00:00:00

abstract：:Examination of routinely stained haematoxylin and eosin sections may sometimes prove inadequate in differentiating partial hydatidiform moles (PHM) from complete hydatidiform moles (CHM). While cytogenetic analysis can aid in the distinction, such facilities are not always available. The possibility of using immunohis...

journal_title：Pathology

authors： Cheah PL,Looi LM

更新日期：1994-04-01 00:00:00

abstract：:Lymphoplasmacytic lymphoma (LPL) represents a distinct type of mature B-cell lymphoma with a substantial subset of cases being associated with Waldenström macroglobulinaemia (WM), defined as primarily bone marrow involvement and the presence of an IgM monoclonal paraprotein. MYD88 L265P mutation, although not specific...

journal_title：Pathology

authors： Wang W,Lin P

更新日期：2020-01-01 00:00:00

abstract：:The estimation of plasma alanine aminotransferase (ALT) has been proposed as a surrogate test to identify potential non-A, non-B hepatitis carriers in blood donor populations. This report describes an ALT screening procedure which uses wells of microtitration trays as reactant vessels. The method utilizes a rate readi...

journal_title：Pathology

authors： Hyland CA,Douglas R,Mazzocchi R,Young IF

更新日期：1988-07-01 00:00:00

abstract：AIMS:Mixed type liposarcomas are rare. Here, we analysed the characteristics of an unusual case of mixed type liposarcoma, which consisted of a well-differentiated liposarcoma (WDL) and a pleomorphic liposarcoma (PL), with a special emphasis on molecular alterations. METHODS:Microscopic and immunohistochemical approac...

journal_title：Pathology

authors： Kim JI,Choi KU,Lee IS,Moon TY,Lee CH,Kim HW,Kim JY,Park DY,Sol MY

更新日期：2006-04-01 00:00:00

abstract：:A case of solitary cervical intramedullary schwannoma with an extramedullary extension is reported. This case demonstrates the difficulty of radiologic diagnosis of these tumours and the necessity for pre-treatment biopsy. ...

journal_title：Pathology

authors： Garen PD,Collett MG,Harper CG

更新日期：1988-07-01 00:00:00

abstract：AIMS:We have identified in malignant melanoma an angio-tumoural complex in which tumour cells occupy a pericytic location along the endothelium of microvessels without evidence of intravasation. This pericytic angiotropism of melanoma cells, without any sign of intravasation, suggests that melanoma cells may migrate al...

journal_title：Pathology

authors： Barnhill RL,Lugassy C

更新日期：2004-10-01 00:00:00

abstract：:A patient initially treated for iron deficiency anemia was later found to have myelofibrosis. She developed increasing splenomegaly and then a mass in the right iliac fossa for which a right hemicolectomy was performed. Histopathology demonstrated extramedullary hemopoiesis in the spleen and cecum. The patient subsequ...

journal_title：Pathology

authors： Sunderland K,Barratt J,Pidcock M

更新日期：1994-01-01 00:00:00

abstract：:Rare tumours are a heterogeneous group of conditions that encompass benign to malignant lesions both of stromal and epithelial origin. Here some of these tumours are described, in which the authors have most familiarity. An outline of medullary carcinoma is also presented. ...

journal_title：Pathology

authors： Foschini MP,Eusebi V

更新日期：2009-01-01 00:00:00

abstract：:A 5-year-old Chinese boy had dull pain in his right knee for about one year. An intraosseous osteolytic lesion in the metaphysis of the right lower femur was curetted. The diagnosis of desmoplastic fibroma, possibly the first in a Hong Kong Chinese, was based on the clinical, radiological and histological findings. Ab...

journal_title：Pathology

authors： Chan KW,Pun WK,Choi CH

更新日期：1987-04-01 00:00:00

abstract：:Rapid rescreening was established in our laboratory in 1995, following the publication of several studies indicating improved sensitivity for the detection of abnormalities in cervical smears. During the study period, 285,841 negative smears (representing 89.09% of the total workload) were rapidly rescreened. A total ...

journal_title：Pathology

authors： Wright RG,Halford JA,Ditchmen EJ

更新日期：1999-11-01 00:00:00

abstract：AIMS:Matrix metalloproteinases (MMPs) have various functions that play roles in carcinoma development. In this study, we investigated the expression of two representative MMPs, MMP-7 and MMP-11, in papillary thyroid carcinomas. METHODS:We immunohistochemically investigated the expression of these MMPs in 196 cases of ...

journal_title：Pathology

authors： Ito Y,Yoshida H,Kakudo K,Nakamura Y,Kuma K,Miyauchi A

更新日期：2006-10-01 00:00:00

abstract：:Assessment of the risk of lymph node invasion and tumour recurrence is critical to determine whether additional surgery is required in patients with endoscopically-removed pT1 colorectal cancer (CRC). A reproducible assessment of this risk of recurrence based on histopathological parameters is crucial for relevant the...

journal_title：Pathology

authors： Barel F,Auffret A,Cariou M,Kermarrec T,Samaison L,Bourhis A,Badic B,Jézéquel J,Cholet F,Bail JP,Marcorelles P,Nousbaum JB,Robaszkiewicz M,Doucet L,Uguen A

更新日期：2019-01-01 00:00:00

abstract：:Iron tablets are widely used in the community. Severe, sometimes lethal, damage to the gastrointestinal tract following overdose is well known, but there is less appreciation of the damage that can be caused by therapeutic dosage. In this histological study of three esophageal lesions and six gastric lesions (includin...

journal_title：Pathology

authors： Eckstein RP,Symons P

更新日期：1996-05-01 00:00:00

abstract：:The early and late effects of wound healing on tumour development at a distant site were evaluated morphologically in an experimental model of colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH). Random bred male Wistar rats were given subcutaneous injections of DMH (20 mg/kg) or saline, once a week, for eight...

journal_title：Pathology

authors： Sequeira JL,Kobayasi SS,Rodrigues MA

更新日期：2000-11-01 00:00:00

abstract：AIM:Performance measures for Australian laboratories reporting cervical cytology are a set of quantifiable measures relating to the profile and accuracy of reporting. This study reviews aggregate data collected over the ten years in which participation in the performance measures has been mandatory. METHODS:Laboratori...

journal_title：Pathology

authors： Shield PW,Finnimore J,Cummings M,Wright RG

更新日期：2010-12-01 00:00:00

abstract：:A survey conducted by the Australian Association of Clinical Biochemists Porphyrin Working Party on urinary porphobilinogen screening showed good sensitivity (75-97.5%). This is contrary to reports in the literature and to our own observations. We therefore assessed a widely used screening method (Watson-Schwartz) and...

journal_title：Pathology

authors： Buttery JE,Carrera AM,Pannall PR

更新日期：1990-10-01 00:00:00

abstract：:TGF-β induces epithelial-mesenchymal transition (EMT), which is involved in tumour progression. This study aims to identify and characterise novel factors potentially related to TGF-β-mediated tumour aggression in breast cancer. We treated the human mammary epithelial cell line MCF10A with TGF-β and observed TGF-β-dep...

journal_title：Pathology

authors： Lien HC,Lee YH,Juang YL,Lu YT

更新日期：2019-06-01 00:00:00

abstract：:The causes and pathogenesis of severe childhood pneumonia in a developing country were studied in lungs removed at autopsy from 119 Bangladeshi children who presented with pneumonia and/or diarrhea. Pneumonia was observed in 93 patients. Morphologic features included acute alveolar exudate in 51% (of the 93 patients),...

journal_title：Pathology

authors： Tomashefski JF Jr,Butler T,Islam M

更新日期：1989-04-01 00:00:00

abstract：:A sequential study has been made of the ultrastructure of local renal graft-versus-host reactions produced in cyclophosphamide-pretreated rats by injection of either allogeneic or xenogeneic (mouse) spleen cells beneath the renal capsule. Early in the reaction, immunoblasts were seen between the outer cortical tubules...

journal_title：Pathology

authors： Davies DJ,Conway MS

更新日期：1975-10-01 00:00:00

abstract：:A calcified nodule on the liver of a 62-year-old man from North Carolina, USA, contained a degenerated nymph of Linguatula serrata. The nodule was incidentally discovered at laparotomy for malignant lymphoma and cholelithiasis. The cuticle was all that remained of the parasite, but sclerotized openings and large spine...

journal_title：Pathology

authors： Baird JK,Kassebaum LJ,Ludwig GK

更新日期：1988-04-01 00:00:00

abstract：AIM:We investigated the role of renal sympathetic innervation in the deterioration of renal haemodynamic and excretory functions during the early post-ischaemic phase of renal ischaemia/reperfusion injury. METHODS:Anaesthetised male Sprague-Dawley rats were subjected to unilateral renal ischaemia by clamping the left ...

journal_title：Pathology

authors： Salman IM,Ameer OZ,Sattar MA,Abdullah NA,Yam MF,Najim HS,Khan AH,Johns EJ

更新日期：2010-04-01 00:00:00

abstract：:Various tumour markers have been evaluated in malignant pleural effusions, but not CD66c. This study evaluated the diagnostic ability of CD66c in lung adenocarcinoma-associated malignant pleural effusions (LA-MPEs) and compared it with other known tumour markers. Forty-seven cases of LA-MPE and 52 cases of benign pleu...

journal_title：Pathology

authors： Son SM,Han HS,An JY,Choe KH,Lee KM,Lee KH,Kim SS,Lee YM,Lee HC,Song HG,Lee OJ

更新日期：2015-02-01 00:00:00

abstract：:Isolation of the new pandemic virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for diagnostic and research purposes including assessment of novel therapeutics. Several primary and continuous cell lines are currently used, and new organoid and engineered cell lines are being developed for...

journal_title：Pathology

authors： Stelzer-Braid S,Walker GJ,Aggarwal A,Isaacs SR,Yeang M,Naing Z,Ospina Stella A,Turville SG,Rawlinson WD

更新日期：2020-12-01 00:00:00

abstract：:Cervical biopsies obtained by colposcopic direction from 358 women were histologically examined for squamous dysplasia (cervical intra-epithelial neoplasia; CIN) and human papillomavirus (HPV) infection. Of the 358 biopsies, 136 were stained by an immunoperoxidase method using an antiserum against genus-specific (comm...

journal_title：Pathology

authors： Sterrett GF,Alessandri LM,Pixley E,Kulski JK

更新日期：1987-01-01 00:00:00

abstract：AIMS:Mounting evidence indicates that deregulation of apoptosis is involved in the mechanisms of cancer development. Bax-interacting factor-1 (Bif-1) interacts with both Bax and Bak that are crucial for the intrinsic apoptosis signalling. Functionally, loss of Bif-1 expression has been proven to enhance tumorigenesis. ...

journal_title：Pathology

authors： Kim SY,Oh YL,Kim KM,Jeong EG,Kim MS,Yoo NJ,Lee SH

更新日期：2008-10-01 00:00:00

abstract：:Colonic mucosal biopsies from patients with melanosis coli were examined by electron microscopy. They showed apoptosis of colonic surface epithelial cells and phagocytosis of resulting apoptotic bodies by intraepithelial macrophages. The latter migrated to the lamina propria where intracellular degradation of the apop...

journal_title：Pathology

authors： Walker NI,Smith MM,Smithers BM

更新日期：1993-04-01 00:00:00

abstract：AIMS:To investigate KAI1 and survivin expression in infiltrating ductal carcinomas, and to evaluate the relationship between clinicopathological factors and KAI1 and survivin expression levels in breast cancers. METHODS AND RESULTS:KAI and survivin expression levels were measured in 62 patients, using immunohistochemi...

journal_title：Pathology

authors： Son BH,Choi JS,Lee JH

更新日期：2005-04-01 00:00:00